For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTALWLVLYGAVLAWFAPPVLRRLTGGGVSPSMGVAAWLATVAAVLVAWLAAVVLVVDATSSSVLNGSV VTLCLELFGFSDHTPLAGRLGSIALIGGGLLTSAVVALRLGRCLARLRTRSHEHAHAARIVGRPTDHPHV VVVEADLPAAYCVIGRPHAIVVTSAAVRSLDRAQLKAVLAHEHAHLSGHHHHILMVLRALAATLPHLPLF AGAHQAVAELLEMCADDTAARRVGTRPLLTGLLALAGHRPPVAEGLAAAATAVITRAERLVTPTRRHVRW RHRALLSVAIATMLATPAFIQVLCHH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0897 | - | - | 100% (306) | hypothetical protein Mflv_0897 |
M. gilvum PYR-GCK | Mflv_2841 | - | e-132 | 74.51% (306) | peptidase M48, Ste24p |
M. gilvum PYR-GCK | Mflv_2815 | - | 2e-60 | 45.95% (309) | peptidase M48, Ste24p |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1876c | - | 6e-19 | 27.56% (283) | hypothetical protein Mb1876c |
M. tuberculosis H37Rv | Rv1845c | - | 6e-19 | 27.56% (283) | hypothetical protein Rv1845c |
M. leprae Br4923 | MLBr_02064 | - | 2e-18 | 26.35% (315) | integral membrane protein |
M. abscessus ATCC 19977 | MAB_4859 | - | 1e-57 | 42.90% (303) | hypothetical protein MAB_4859 |
M. marinum M | MMAR_5059 | - | 7e-65 | 44.48% (308) | peptidase M48 like- protein |
M. avium 104 | MAV_2870 | - | 4e-19 | 26.88% (279) | integral membrane protein |
M. smegmatis MC2 155 | MSMEG_3631 | - | 2e-15 | 25.18% (274) | integral membrane protein |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_4135 | - | 5e-63 | 43.83% (308) | peptidase M48 like- protein |
M. vanbaalenii PYR-1 | Mvan_3654 | - | 1e-163 | 94.12% (306) | hypothetical protein Mvan_3654 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1876c|M.bovis_AF2122/97 -MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSS Rv1845c|M.tuberculosis_H37Rv -MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSS MLBr_02064|M.leprae_Br4923 -MSALAFTILAVLLVGPTPTLVARSTWPLRAPRAAMVLWQTIALAAALST MAV_2870|M.avium_104 -MSALAFTILAVLLTGPVPAMLARARWPLRAPRAAMVLWQAVALAAVLSA MSMEG_3631|M.smegmatis_MC2_155 -MSALAFTLVALALVGPVPAMLARASWPLRAPRAAIVLWQSIALAAVLSA Mflv_0897|M.gilvum_PYR-GCK MTTALWLVLYGAVLAWFAPPVLRRLTGGGVSPSMGVAAWLATVAAVLVAW Mvan_3654|M.vanbaalenii_PYR-1 MTTALWLVLYGAVLAWLAPPVLRRLTGGGVSPSMGVAAWLATVAAVLAAW MMAR_5059|M.marinum_M MNAALLLFAYASALIWVGPVLLRRVTGTGVHPRLAVASWLSAVFAAIAAW MUL_4135|M.ulcerans_Agy99 MNAALLLFAYASALIWVGPVLLRRVTGTGVHPRLAVASWLSAVFAAIAAW MAB_4859|M.abscessus_ATCC_1997 MSIAVCLLLYSVAVLIFGPRLLRRLTRTGYAPRLAITAWLAAIVSVLGTW *: : . : * :: * * .:. * : :. : Mb1876c|M.bovis_AF2122/97 FSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLVG Rv1845c|M.tuberculosis_H37Rv FSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLVG MLBr_02064|M.leprae_Br4923 FSAGIAIASRVLMPGPDGRLTASVIGAAGRLGWPLWAAYVAAFALTVLVG MAV_2870|M.avium_104 FSAGIAIATRVLVPGPDGRPTTSILGAEGRLGWPLWTAYIGVFALTVLVG MSMEG_3631|M.smegmatis_MC2_155 FSAGIAIASRLFVPGADGRPTATITSEIDVLGWPLWLLYVVVFSLTLFIG Mflv_0897|M.gilvum_PYR-GCK LAAVVLVVDATSSSVLNGS---VVTLCLELFGFSDHTPLAGRLG---SIA Mvan_3654|M.vanbaalenii_PYR-1 LAAVVLVVNATSNSILDGS---VVTLCLELFGFSDHTPLAGRLG---SIA MMAR_5059|M.marinum_M VGALVFLGAAVLDSIWRHR---ALALCLKELGLAGELGLPRGIASALAVG MUL_4135|M.ulcerans_Agy99 VGALVSLGAAVLDSIWRHR---ALALCVKELGLAGELGLPRGIASALAVG MAB_4859|M.abscessus_ATCC_1997 ISAAALIVIDVVRHWNSPA---VVLAACAARLHAMLIGQAGAAAQVGLLA ..* : . . . :. Mb1876c|M.bovis_AF2122/97 ARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVLD Rv1845c|M.tuberculosis_H37Rv ARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVLD MLBr_02064|M.leprae_Br4923 ARLIVAIVRVAIATRRRRAHHRMVVDLVGVGHNAALAQPCARARDLRVLE MAV_2870|M.avium_104 ARLMVAVVRVAIANRRRRAHHRMVVDLVGMGHGAALSQPCSRTRDLRVLD MSMEG_3631|M.smegmatis_MC2_155 ARLCVAIVQVGVATRRRRAHHRMMVDLLSKSRDAVPAHLRTPASGLRILD Mflv_0897|M.gilvum_PYR-GCK LIGGGLLTSAVVALRLGRCLARLRTRSHEHAHAARIVGRPTDHPHVVVVE Mvan_3654|M.vanbaalenii_PYR-1 LIGGGLLTSAVVALRLGRCLAGLRTRSHEHAHAARIVGRPTDHPHVVVVE MMAR_5059|M.marinum_M VLSTGAVATVIACWRMGRQLRRQRSASRLHAATARTIGGASDWPGVVVVP MUL_4135|M.ulcerans_Agy99 VLSTGAVATVIVCWRMGRQLRGQRSASRLHAATARTIGGVSDWPGVVVVP MAB_4859|M.abscessus_ATCC_1997 LSAAGSIAAPALGVRLARTLIRLRDTAHEHAYAVHMVGRRTAEGDVMVLE :. * * . : : :: Mb1876c|M.bovis_AF2122/97 VAQPLAYCLPGVR-SRVVVSEGTLTALADAEVAAILTHERAHLRARHDLV Rv1845c|M.tuberculosis_H37Rv VAQPLAYCLPGVR-SRVVVSEGTLTALADAEVAAILTHERAHLRARHDLV MLBr_02064|M.leprae_Br4923 VAQPLAYCLPGVR-SRVVVSEGALTKLNDTEVTAILTHERAHLRARHDLV MAV_2870|M.avium_104 VPQPLAYCLPGVR-SRVVVSEGTLSTLADAEVSAILTHERAHLRARHDLV MSMEG_3631|M.smegmatis_MC2_155 VAQPLAYCLPGVR-SRVVVSEGTLDTLSPDEVDAILTHERAHLRARHDLV Mflv_0897|M.gilvum_PYR-GCK ADLPAAYCVIGRP-HAIVVTSAAVRSLDRAQLKAVLAHEHAHLSGHHHHI Mvan_3654|M.vanbaalenii_PYR-1 ADLPAAYCVIGRP-HAIVVTSAAVKSLNRAQLKAVLAHENAHLTGHHHHI MMAR_5059|M.marinum_M APQPAAYCVTGRPNSVIVVTSGALGRLDEPQLAAVLAHEYAHLASRHHDL MUL_4135|M.ulcerans_Agy99 APQPAAYCVTGRPNSVIVVTSGALGRLDEPQLAAVLAHEYAHLASRHHDL MAB_4859|M.abscessus_ATCC_1997 APEAAAYCVAGRP-SAIVLTTGALAVLDDAQVAAILAHERAHLAGHHPQL . . ***: * :*:: .:: * :: *:*:** *** .:* : Mb1876c|M.bovis_AF2122/97 LEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARALV Rv1845c|M.tuberculosis_H37Rv LEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARALV MLBr_02064|M.leprae_Br4923 LEAFTAVHAAFPRLVRSSAALSAVRLLVELLADDAAVRAAGRTPLARALV MAV_2870|M.avium_104 LEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRAPLARALV MSMEG_3631|M.smegmatis_MC2_155 LEMFTAVHAAFPRFVRSASALDAVRLLIELLADDAAVRIAGPTPLARALV Mflv_0897|M.gilvum_PYR-GCK LMVLRALAATLPHLPLFAGAHQAVAELLEMCADDTAARRVGTRPLLTGLL Mvan_3654|M.vanbaalenii_PYR-1 LMVLRALAATLPHLPLFACAHQAVAELLEMCADDTAARRVGTRPLLAGLL MMAR_5059|M.marinum_M LMALRALASSLPRLPLFAAAAKVVADLLEMCADDVAVRSHGKMALLRGLL MUL_4135|M.ulcerans_Agy99 LMALRALASSLPRLPLFAAAAKVVADLLEMCADDVAVRSHGKMALLRGLL MAB_4859|M.abscessus_ATCC_1997 VSVLRALADVFPRVRLMTDGSAQISRLLEMCADDSAARHHGRGVLLSGLM : : *: :*:. : . : *:*: *** *.* * * .*: Mb1876c|M.bovis_AF2122/97 ACASG-RAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLVV Rv1845c|M.tuberculosis_H37Rv ACASG-RAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLVV MLBr_02064|M.leprae_Br4923 ACASG-QAPSGALAAGGNTTVLRVRRLSGRSNSAVVSAAAYLAAAIVLLV MAV_2870|M.avium_104 ACASG-RAPSGALAAGGPSTVVRVRRLGGRGNSPLLSAAAYLAAAAVFVV MSMEG_3631|M.smegmatis_MC2_155 TCAAG-RTPSGALAAGGPTTVIRVRRLGGKPNSLTLSVIAYLAAVAILVV Mflv_0897|M.gilvum_PYR-GCK ALAGHRPPVAEGLAAAATAVITRAERLVTPTRRHVRWRHRALLSVAIATM Mvan_3654|M.vanbaalenii_PYR-1 ALAGHRPPVTEGLAAAAMAVITRAERLVTPTRRHVQWRHRALLVAAIATM MMAR_5059|M.marinum_M ALTEGPAMAPAALGAANTATVARAERLAISVSRRSWWQERLMLWATIGLA MUL_4135|M.ulcerans_Agy99 ALTEGPAMAPVALGAANTATVARAERLAISVSRRSWWQERLMLWATSGLA MAB_4859|M.abscessus_ATCC_1997 DLAG--TVPAAAVGAANVAVLDRAERLLTPPEPPARAWARIALTMCVAAI : . .:... :.: *..** Mb1876c|M.bovis_AF2122/97 PTVALAVPWLTQLQRLFIA-- Rv1845c|M.tuberculosis_H37Rv PTVALAVPWLTQLQRLFIA-- MLBr_02064|M.leprae_Br4923 PTVALAVPWLTELQRLFNI-- MAV_2870|M.avium_104 PTVALAVPWLTELERLLNL-- MSMEG_3631|M.smegmatis_MC2_155 PTVAVAVPWLTELHRLFSGLT Mflv_0897|M.gilvum_PYR-GCK LATPAFIQVLCHH-------- Mvan_3654|M.vanbaalenii_PYR-1 LATPAFIQVLCHH-------- MMAR_5059|M.marinum_M VVSPMILGLACRL-------- MUL_4135|M.ulcerans_Agy99 VVSSMFLGLACRL-------- MAB_4859|M.abscessus_ATCC_1997 SAGPLVTIALATSGALLCSP- . .