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TTALWLVLYGAVLAWLAPPVLRRLTGGGVSPSMGVAAWLATVAAVLAAWLAAVVLVVNATSNSILDGSVV TLCLELFGFSDHTPLAGRLGSIALIGGGLLTSAVVALRLGRCLAGLRTRSHEHAHAARIVGRPTDHPHVV VVEADLPAAYCVIGRPHAIVVTSAAVKSLNRAQLKAVLAHENAHLTGHHHHILMVLRALAATLPHLPLFA CAHQAVAELLEMCADDTAARRVGTRPLLAGLLALAGHRPPVTEGLAAAAMAVITRAERLVTPTRRHVQWR HRALLVAAIATMLATPAFIQVLCHH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3654 | - | - | 100% (306) | hypothetical protein Mvan_3654 |
| M. vanbaalenii PYR-1 | Mvan_3707 | - | 2e-57 | 43.46% (306) | peptidase M48, Ste24p |
| M. vanbaalenii PYR-1 | Mvan_5555 | - | 6e-52 | 40.00% (310) | peptidase M56, BlaR1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1876c | - | 5e-19 | 28.87% (284) | hypothetical protein Mb1876c |
| M. gilvum PYR-GCK | Mflv_0897 | - | 1e-163 | 94.12% (306) | hypothetical protein Mflv_0897 |
| M. tuberculosis H37Rv | Rv1845c | - | 5e-19 | 28.87% (284) | hypothetical protein Rv1845c |
| M. leprae Br4923 | MLBr_02064 | - | 7e-20 | 27.88% (312) | integral membrane protein |
| M. abscessus ATCC 19977 | MAB_4859 | - | 5e-54 | 40.46% (304) | hypothetical protein MAB_4859 |
| M. marinum M | MMAR_5059 | - | 2e-63 | 44.48% (308) | peptidase M48 like- protein |
| M. avium 104 | MAV_2870 | - | 9e-20 | 27.74% (310) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_3631 | - | 1e-15 | 27.05% (281) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4135 | - | 2e-63 | 44.48% (308) | peptidase M48 like- protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1876c|M.bovis_AF2122/97 -MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSS
Rv1845c|M.tuberculosis_H37Rv -MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSS
MLBr_02064|M.leprae_Br4923 -MSALAFTILAVLLVGPTPTLVARSTWPLRAPRAAMVLWQTIALAAALST
MAV_2870|M.avium_104 -MSALAFTILAVLLTGPVPAMLARARWPLRAPRAAMVLWQAVALAAVLSA
MSMEG_3631|M.smegmatis_MC2_155 -MSALAFTLVALALVGPVPAMLARASWPLRAPRAAIVLWQSIALAAVLSA
Mvan_3654|M.vanbaalenii_PYR-1 MTTALWLVLYGAVLAWLAPPVLRRLTGGGVSPSMGVAAWLATVAAVLAAW
Mflv_0897|M.gilvum_PYR-GCK MTTALWLVLYGAVLAWFAPPVLRRLTGGGVSPSMGVAAWLATVAAVLVAW
MMAR_5059|M.marinum_M MNAALLLFAYASALIWVGPVLLRRVTGTGVHPRLAVASWLSAVFAAIAAW
MUL_4135|M.ulcerans_Agy99 MNAALLLFAYASALIWVGPVLLRRVTGTGVHPRLAVASWLSAVFAAIAAW
MAB_4859|M.abscessus_ATCC_1997 MSIAVCLLLYSVAVLIFGPRLLRRLTRTGYAPRLAITAWLAAIVSVLGTW
*: : . : * :: * * .:. * : :. :
Mb1876c|M.bovis_AF2122/97 FSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLVG
Rv1845c|M.tuberculosis_H37Rv FSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLVG
MLBr_02064|M.leprae_Br4923 FSAGIAIASRVLMPGPDGRLTASVIGAAGRLGWPLWAAYVAAFALTVLVG
MAV_2870|M.avium_104 FSAGIAIATRVLVPGPDGRPTTSILGAEGRLGWPLWTAYIGVFALTVLVG
MSMEG_3631|M.smegmatis_MC2_155 FSAGIAIASRLFVPGADGRPTATITSEIDVLGWPLWLLYVVVFSLTLFIG
Mvan_3654|M.vanbaalenii_PYR-1 LAAVVLVVNATSNSILDGS---VVTLCLELFGFSDHTPLAGRLG---SIA
Mflv_0897|M.gilvum_PYR-GCK LAAVVLVVDATSSSVLNGS---VVTLCLELFGFSDHTPLAGRLG---SIA
MMAR_5059|M.marinum_M VGALVFLGAAVLDSIWRHR---ALALCLKELGLAGELGLPRGIASALAVG
MUL_4135|M.ulcerans_Agy99 VGALVSLGAAVLDSIWRHR---ALALCVKELGLAGELGLPRGIASALAVG
MAB_4859|M.abscessus_ATCC_1997 ISAAALIVIDVVRHWNSPA---VVLAACAARLHAMLIGQAGAAAQVGLLA
..* : . . . :.
Mb1876c|M.bovis_AF2122/97 ARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVLD
Rv1845c|M.tuberculosis_H37Rv ARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVLD
MLBr_02064|M.leprae_Br4923 ARLIVAIVRVAIATRRRRAHHRMVVDLVGVGHNAALAQPCARARDLRVLE
MAV_2870|M.avium_104 ARLMVAVVRVAIANRRRRAHHRMVVDLVGMGHGAALSQPCSRTRDLRVLD
MSMEG_3631|M.smegmatis_MC2_155 ARLCVAIVQVGVATRRRRAHHRMMVDLLSKSRDAVPAHLRTPASGLRILD
Mvan_3654|M.vanbaalenii_PYR-1 LIGGGLLTSAVVALRLGRCLAGLRTRSHEHAHAARIVGRPTDHPHVVVVE
Mflv_0897|M.gilvum_PYR-GCK LIGGGLLTSAVVALRLGRCLARLRTRSHEHAHAARIVGRPTDHPHVVVVE
MMAR_5059|M.marinum_M VLSTGAVATVIACWRMGRQLRRQRSASRLHAATARTIGGASDWPGVVVVP
MUL_4135|M.ulcerans_Agy99 VLSTGAVATVIVCWRMGRQLRGQRSASRLHAATARTIGGVSDWPGVVVVP
MAB_4859|M.abscessus_ATCC_1997 LSAAGSIAAPALGVRLARTLIRLRDTAHEHAYAVHMVGRRTAEGDVMVLE
:. * * . : : ::
Mb1876c|M.bovis_AF2122/97 VAQPLAYCLPGVR-SRVVVSEGTLTALADAEVAAILTHERAHLRARHDLV
Rv1845c|M.tuberculosis_H37Rv VAQPLAYCLPGVR-SRVVVSEGTLTALADAEVAAILTHERAHLRARHDLV
MLBr_02064|M.leprae_Br4923 VAQPLAYCLPGVR-SRVVVSEGALTKLNDTEVTAILTHERAHLRARHDLV
MAV_2870|M.avium_104 VPQPLAYCLPGVR-SRVVVSEGTLSTLADAEVSAILTHERAHLRARHDLV
MSMEG_3631|M.smegmatis_MC2_155 VAQPLAYCLPGVR-SRVVVSEGTLDTLSPDEVDAILTHERAHLRARHDLV
Mvan_3654|M.vanbaalenii_PYR-1 ADLPAAYCVIGRP-HAIVVTSAAVKSLNRAQLKAVLAHENAHLTGHHHHI
Mflv_0897|M.gilvum_PYR-GCK ADLPAAYCVIGRP-HAIVVTSAAVRSLDRAQLKAVLAHEHAHLSGHHHHI
MMAR_5059|M.marinum_M APQPAAYCVTGRPNSVIVVTSGALGRLDEPQLAAVLAHEYAHLASRHHDL
MUL_4135|M.ulcerans_Agy99 APQPAAYCVTGRPNSVIVVTSGALGRLDEPQLAAVLAHEYAHLASRHHDL
MAB_4859|M.abscessus_ATCC_1997 APEAAAYCVAGRP-SAIVLTTGALAVLDDAQVAAILAHERAHLAGHHPQL
. . ***: * :*:: .:: * :: *:*:** *** .:* :
Mb1876c|M.bovis_AF2122/97 LEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARALV
Rv1845c|M.tuberculosis_H37Rv LEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARALV
MLBr_02064|M.leprae_Br4923 LEAFTAVHAAFPRLVRSSAALSAVRLLVELLADDAAVRAAGRTPLARALV
MAV_2870|M.avium_104 LEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRAPLARALV
MSMEG_3631|M.smegmatis_MC2_155 LEMFTAVHAAFPRFVRSASALDAVRLLIELLADDAAVRIAGPTPLARALV
Mvan_3654|M.vanbaalenii_PYR-1 LMVLRALAATLPHLPLFACAHQAVAELLEMCADDTAARRVGTRPLLAGLL
Mflv_0897|M.gilvum_PYR-GCK LMVLRALAATLPHLPLFAGAHQAVAELLEMCADDTAARRVGTRPLLTGLL
MMAR_5059|M.marinum_M LMALRALASSLPRLPLFAAAAKVVADLLEMCADDVAVRSHGKMALLRGLL
MUL_4135|M.ulcerans_Agy99 LMALRALASSLPRLPLFAAAAKVVADLLEMCADDVAVRSHGKMALLRGLL
MAB_4859|M.abscessus_ATCC_1997 VSVLRALADVFPRVRLMTDGSAQISRLLEMCADDSAARHHGRGVLLSGLM
: : *: :*:. : . : *:*: *** *.* * * .*:
Mb1876c|M.bovis_AF2122/97 ACASG-RAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLVV
Rv1845c|M.tuberculosis_H37Rv ACASG-RAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLVV
MLBr_02064|M.leprae_Br4923 ACASG-QAPSGALAAGGNTTVLRVRRLSGRSNSAVVSAAAYLAAAIVLLV
MAV_2870|M.avium_104 ACASG-RAPSGALAAGGPSTVVRVRRLGGRGNSPLLSAAAYLAAAAVFVV
MSMEG_3631|M.smegmatis_MC2_155 TCAAG-RTPSGALAAGGPTTVIRVRRLGGKPNSLTLSVIAYLAAVAILVV
Mvan_3654|M.vanbaalenii_PYR-1 ALAGHRPPVTEGLAAAAMAVITRAERLVTPTRRHVQWRHRALLVAAIATM
Mflv_0897|M.gilvum_PYR-GCK ALAGHRPPVAEGLAAAATAVITRAERLVTPTRRHVRWRHRALLSVAIATM
MMAR_5059|M.marinum_M ALTEGPAMAPAALGAANTATVARAERLAISVSRRSWWQERLMLWATIGLA
MUL_4135|M.ulcerans_Agy99 ALTEGPAMAPVALGAANTATVARAERLAISVSRRSWWQERLMLWATSGLA
MAB_4859|M.abscessus_ATCC_1997 DLAG--TVPAAAVGAANVAVLDRAERLLTPPEPPARAWARIALTMCVAAI
: . .:... :.: *..**
Mb1876c|M.bovis_AF2122/97 PTVALAVPWLTQLQRLFIA--
Rv1845c|M.tuberculosis_H37Rv PTVALAVPWLTQLQRLFIA--
MLBr_02064|M.leprae_Br4923 PTVALAVPWLTELQRLFNI--
MAV_2870|M.avium_104 PTVALAVPWLTELERLLNL--
MSMEG_3631|M.smegmatis_MC2_155 PTVAVAVPWLTELHRLFSGLT
Mvan_3654|M.vanbaalenii_PYR-1 LATPAFIQVLCHH--------
Mflv_0897|M.gilvum_PYR-GCK LATPAFIQVLCHH--------
MMAR_5059|M.marinum_M VVSPMILGLACRL--------
MUL_4135|M.ulcerans_Agy99 VVSSMFLGLACRL--------
MAB_4859|M.abscessus_ATCC_1997 SAGPLVTIALATSGALLCSP-
. .