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TVAAALLLYVAAVLAIGPKLLVHITADGGAPRLAIAAWITAVVTVLGCSVAAVALLLIEAAGHWDSPDAL LVTCLERLRAILVGHAGWPARIVATVAVAIAVGSLIAVVIRLSRALGRMRTHTFAHADAVRLVGRSHGSD VVVIEASEPAAYCVAGRPPAIVVTSAALAALDESQLAAVVAHERAHLDGRHAYIVAAARGLTAALPTCGL FASAASHISSLLEMCADDAAARRHGRQPLLAGLLTLAGATAPAQGLAAAGIAVLARAERLSKPPRRFARI QTQVTLSGAVAAMAATPLAIVTLSLSGVLICFA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2815 | - | - | 100% (314) | peptidase M48, Ste24p |
| M. gilvum PYR-GCK | Mflv_0897 | - | 2e-60 | 45.95% (309) | hypothetical protein Mflv_0897 |
| M. gilvum PYR-GCK | Mflv_2841 | - | 7e-60 | 43.79% (306) | peptidase M48, Ste24p |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1876c | - | 1e-32 | 32.30% (322) | hypothetical protein Mb1876c |
| M. tuberculosis H37Rv | Rv1845c | - | 1e-32 | 32.30% (322) | hypothetical protein Rv1845c |
| M. leprae Br4923 | MLBr_02064 | - | 1e-33 | 33.33% (321) | integral membrane protein |
| M. abscessus ATCC 19977 | MAB_4859 | - | 5e-77 | 49.20% (313) | hypothetical protein MAB_4859 |
| M. marinum M | MMAR_5059 | - | 2e-50 | 42.26% (310) | peptidase M48 like- protein |
| M. avium 104 | MAV_2870 | - | 7e-30 | 31.47% (286) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_3631 | - | 8e-26 | 29.07% (313) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4135 | - | 2e-48 | 41.32% (317) | peptidase M48 like- protein |
| M. vanbaalenii PYR-1 | Mvan_3707 | - | 1e-164 | 95.54% (314) | peptidase M48, Ste24p |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1876c|M.bovis_AF2122/97 -MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSS
Rv1845c|M.tuberculosis_H37Rv -MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLSS
MLBr_02064|M.leprae_Br4923 -MSALAFTILAVLLVGPTPTLVARSTWPLRAPRAAMVLWQTIALAAALST
MAV_2870|M.avium_104 -MSALAFTILAVLLTGPVPAMLARARWPLRAPRAAMVLWQAVALAAVLSA
MSMEG_3631|M.smegmatis_MC2_155 -MSALAFTLVALALVGPVPAMLARASWPLRAPRAAIVLWQSIALAAVLSA
Mflv_2815|M.gilvum_PYR-GCK MTVAAALLLYVAAVLAIGPKLLVHITADGGAPRLAIAAWITAVVTVLGCS
Mvan_3707|M.vanbaalenii_PYR-1 MTVAAALLLYVAAVLAIGPKLLVHITADGGAPRLAIAAWITAVVTVLGCS
MAB_4859|M.abscessus_ATCC_1997 MSIAVCLLLYSVAVLIFGPRLLRRLTRTGYAPRLAITAWLAAIVSVLGTW
MMAR_5059|M.marinum_M MNAALLLFAYASALIWVGPVLLRRVTGTGVHPRLAVASWLSAVFAAIAAW
MUL_4135|M.ulcerans_Agy99 MNAALLLFAYASALIWVGPVLLRRVTGTGVHPRLAVASWLSAVFAAIAAW
* : : * :: : ** *:. * : .:.
Mb1876c|M.bovis_AF2122/97 FSAGIAIASRLLMPGPDGRPTTSFVGAAGRLG--WPLWAAYITVFALTVL
Rv1845c|M.tuberculosis_H37Rv FSAGIAIASRLLMPGPDGRPTTSFVGAAGRLG--WPLWAAYITVFALTVL
MLBr_02064|M.leprae_Br4923 FSAGIAIASRVLMPGPDGRLTASVIGAAGRLG--WPLWAAYVAAFALTVL
MAV_2870|M.avium_104 FSAGIAIATRVLVPGPDGRPTTSILGAEGRLG--WPLWTAYIGVFALTVL
MSMEG_3631|M.smegmatis_MC2_155 FSAGIAIASRLFVPGADGRPTATITSEIDVLG--WPLWLLYVVVFSLTLF
Mflv_2815|M.gilvum_PYR-GCK VAAVALLLIEAAG--HWDSPDALLVTCLERLRAILVGHAGWPARIVATVA
Mvan_3707|M.vanbaalenii_PYR-1 VAAVALLLVEAAG--HWDSPDALLVTCLERLGAILVGHAGWPARIVATVA
MAB_4859|M.abscessus_ATCC_1997 ISAAALIVIDVVR--HWNSPAVVLAACAARLHAMLIGQAGAAAQVGLLAL
MMAR_5059|M.marinum_M VGALVFLGAAVLDS-IWRHR--ALALCLKELG--LAGELGLPRGIASALA
MUL_4135|M.ulcerans_Agy99 VGALVSLGAAVLDS-IWRHR--ALALCVKELG--LAGELGLPRGIASALA
..* : . * .
Mb1876c|M.bovis_AF2122/97 VGARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRV
Rv1845c|M.tuberculosis_H37Rv VGARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRV
MLBr_02064|M.leprae_Br4923 VGARLIVAIVRVAIATRRRRAHHRMVVDLVGVGHNAALAQPCARARDLRV
MAV_2870|M.avium_104 VGARLMVAVVRVAIANRRRRAHHRMVVDLVGMGHGAALSQPCSRTRDLRV
MSMEG_3631|M.smegmatis_MC2_155 IGARLCVAIVQVGVATRRRRAHHRMMVDLLSKSRDAVPAHLRTPASGLRI
Mflv_2815|M.gilvum_PYR-GCK V---AIAVGSLIAVVIRLSRALGRMRTHTFAHADAVRLVG-RSHGSDVVV
Mvan_3707|M.vanbaalenii_PYR-1 V---AIAVGSLIAVVCRIGRALGRMRTHTFAHADAVRLVG-RSYGSDVVV
MAB_4859|M.abscessus_ATCC_1997 S---AAGSIAAPALGVRLARTLIRLRDTAHEHAYAVHMVGRRTAEGDVMV
MMAR_5059|M.marinum_M VGVLSTGAVATVIACWRMGRQLRRQRSASRLHAATARTIGGASDWPGVVV
MUL_4135|M.ulcerans_Agy99 VGVLSTGAVATVIVCWRMGRQLRGQRSASRLHAATARTIGGVSDWPGVVV
* * . : .: :
Mb1876c|M.bovis_AF2122/97 LDVAQPLAYCLPGVR-SRVVVSEGTLTALADAEVAAILTHERAHLRARHD
Rv1845c|M.tuberculosis_H37Rv LDVAQPLAYCLPGVR-SRVVVSEGTLTALADAEVAAILTHERAHLRARHD
MLBr_02064|M.leprae_Br4923 LEVAQPLAYCLPGVR-SRVVVSEGALTKLNDTEVTAILTHERAHLRARHD
MAV_2870|M.avium_104 LDVPQPLAYCLPGVR-SRVVVSEGTLSTLADAEVSAILTHERAHLRARHD
MSMEG_3631|M.smegmatis_MC2_155 LDVAQPLAYCLPGVR-SRVVVSEGTLDTLSPDEVDAILTHERAHLRARHD
Mflv_2815|M.gilvum_PYR-GCK IEASEPAAYCVAGRP-PAIVVTSAALAALDESQLAAVVAHERAHLDGRHA
Mvan_3707|M.vanbaalenii_PYR-1 IEASEPAAYCVAGRP-PAIVVTTAAMAALDENQLAAVVAHERAHLDGRHA
MAB_4859|M.abscessus_ATCC_1997 LEAPEAAAYCVAGRP-SAIVLTTGALAVLDDAQVAAILAHERAHLAGHHP
MMAR_5059|M.marinum_M VPAPQPAAYCVTGRPNSVIVVTSGALGRLDEPQLAAVLAHEYAHLASRHH
MUL_4135|M.ulcerans_Agy99 VPAPQPAAYCVTGRPNSVIVVTSGALGRLDEPQLAAVLAHEYAHLASRHH
: ..:. ***:.* . :*:: .:: * :: *:::** *** .:*
Mb1876c|M.bovis_AF2122/97 LVLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARA
Rv1845c|M.tuberculosis_H37Rv LVLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARA
MLBr_02064|M.leprae_Br4923 LVLEAFTAVHAAFPRLVRSSAALSAVRLLVELLADDAAVRAAGRTPLARA
MAV_2870|M.avium_104 LVLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRAPLARA
MSMEG_3631|M.smegmatis_MC2_155 LVLEMFTAVHAAFPRFVRSASALDAVRLLIELLADDAAVRIAGPTPLARA
Mflv_2815|M.gilvum_PYR-GCK YIVAAARGLTAALPTCGLFASAASHISSLLEMCADDAAARRHGRQPLLAG
Mvan_3707|M.vanbaalenii_PYR-1 YIVAAARGLTTALPTCGLFASAASHISSLLEMCADDAAARHHGRQPLLAG
MAB_4859|M.abscessus_ATCC_1997 QLVSVLRALADVFPRVRLMTDGSAQISRLLEMCADDSAARHHGRGVLLSG
MMAR_5059|M.marinum_M DLLMALRALASSLPRLPLFAAAAKVVADLLEMCADDVAVRSHGKMALLRG
MUL_4135|M.ulcerans_Agy99 DLLMALRALASSLPRLPLFAAAAKVVADLLEMCADDVAVRSHGKMALLRG
:: .: :* : . : *:*: *** *.* * * .
Mb1876c|M.bovis_AF2122/97 LVACASG-RAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVL
Rv1845c|M.tuberculosis_H37Rv LVACASG-RAPSGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVL
MLBr_02064|M.leprae_Br4923 LVACASG-QAPSGALAAGGNTTVLRVRRLSGRSNSAVVSAAAYLAAAIVL
MAV_2870|M.avium_104 LVACASG-RAPSGALAAGGPSTVVRVRRLGGRGNSPLLSAAAYLAAAAVF
MSMEG_3631|M.smegmatis_MC2_155 LVTCAAG-RTPSGALAAGGPTTVIRVRRLGGKPNSLTLSVIAYLAAVAIL
Mflv_2815|M.gilvum_PYR-GCK LLTLAGA-TAPAQGLAAAGIAVLARAERLSKPPRRFARIQTQVTLSGAVA
Mvan_3707|M.vanbaalenii_PYR-1 LLTLSGA-TTPAHGLAAAGIAVLARAERLSKPPRRFARIQTQVTLSGAVA
MAB_4859|M.abscessus_ATCC_1997 LMDLAG--TVPAAAVGAANVAVLDRAERLLTPPEPPARAWARIALTMCVA
MMAR_5059|M.marinum_M LLALTEGPAMAPAALGAANTATVARAERLAISVSRRSWWQERLMLWATIG
MUL_4135|M.ulcerans_Agy99 LLALTEGPAMAPVALGAANTATVARAERLAISVSRRSWWQERLMLWATSG
*: : .. .:.... :.: *..**
Mb1876c|M.bovis_AF2122/97 VVPTVALAVPWLTQLQRLFIA--
Rv1845c|M.tuberculosis_H37Rv VVPTVALAVPWLTQLQRLFIA--
MLBr_02064|M.leprae_Br4923 LVPTVALAVPWLTELQRLFNI--
MAV_2870|M.avium_104 VVPTVALAVPWLTELERLLNL--
MSMEG_3631|M.smegmatis_MC2_155 VVPTVAVAVPWLTELHRLFSGLT
Mflv_2815|M.gilvum_PYR-GCK AMAATPLAIVTLSLSGVLICFA-
Mvan_3707|M.vanbaalenii_PYR-1 AMAATPLAIVTLSLSGVLICFA-
MAB_4859|M.abscessus_ATCC_1997 AISAGPLVTIALATSGALLCSP-
MMAR_5059|M.marinum_M ------LAVVSPMILG-LACRL-
MUL_4135|M.ulcerans_Agy99 ------LAVVSSMFLG-LACRL-
:. *