For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTRRLTDAPRMSPSRLDVGVERRRRMRPPIHWSLVVRRGIVAGLSAVLLGAAVSGCSSGDDAVAQGGTFE FVSPGGQVDIFYDPPQSRGRPGLIRGPDLMYPNRTLSLDDFAEQVVVINVWGQWCGPCRTEMPELQRVYD ATRDEGVAFLGIDVRDNNRQAAVDFIVDRKVTFPSIYDPPMRTMIALGARYPTTVIPSTIVLDRSHRVAA VFLRALLAEDLEPVVRRLAAETTTGSGPPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2812 | - | - | 100% (240) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen |
| M. gilvum PYR-GCK | Mflv_0052 | - | 3e-83 | 76.60% (188) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal |
| M. gilvum PYR-GCK | Mflv_2869 | - | 3e-63 | 61.05% (190) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0539 | - | 9e-79 | 68.93% (206) | thioredoxin protein |
| M. tuberculosis H37Rv | Rv0526 | - | 9e-79 | 68.93% (206) | thioredoxin protein |
| M. leprae Br4923 | MLBr_02412 | - | 3e-77 | 65.60% (218) | hypothetical protein MLBr_02412 |
| M. abscessus ATCC 19977 | MAB_3976c | - | 7e-69 | 64.10% (195) | thioredoxin |
| M. marinum M | MMAR_0872 | - | 2e-81 | 72.96% (196) | thioredoxin protein (thiol-disulfide interchange protein) |
| M. avium 104 | MAV_4619 | - | 1e-78 | 70.98% (193) | hypothetical protein MAV_4619 |
| M. smegmatis MC2 155 | MSMEG_0971 | - | 5e-84 | 73.74% (198) | hypothetical protein MSMEG_0971 |
| M. thermoresistible (build 8) | TH_2251 | - | 9e-86 | 76.00% (200) | POSSIBLE THIOREDOXIN PROTEIN (THIOL-DISULFIDE INTERCHANGE |
| M. ulcerans Agy99 | MUL_0625 | - | 2e-81 | 70.87% (206) | thioredoxin protein (thiol-disulfide interchange protein) |
| M. vanbaalenii PYR-1 | Mvan_3710 | - | 1e-115 | 92.66% (218) | redoxin domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0872|M.marinum_M --------------------------------------MRRLVIAAAVLA
MUL_0625|M.ulcerans_Agy99 ------------------------------------MTMRRLVIAAAVLA
Mb0539|M.bovis_AF2122/97 -------------------------MQSRATRRSGALTMRRLVIAAAVSA
Rv0526|M.tuberculosis_H37Rv -------------------------MQSRATRRSGALTMRRLVIAAAVSA
MLBr_02412|M.leprae_Br4923 -------------------MIAPATMQSEAMRRSGATIIWRLANAGALLA
MAV_4619|M.avium_104 ------------------------------------MSARVLAMAGAVLA
MAB_3976c|M.abscessus_ATCC_199 --------------------------------------MRLLVAALAALA
Mflv_2812|M.gilvum_PYR-GCK MTRRLTDAPRMSPSRLDVGVERRRRMRPPIHWSLVVRRGIVAGLSAVLLG
Mvan_3710|M.vanbaalenii_PYR-1 -----------------MGIERWRRRRPPTRWLLVIRRGIAAGLSAVLFG
TH_2251|M.thermoresistible__bu -----------------------------------VKRLVVLLVGTAML-
MSMEG_0971|M.smegmatis_MC2_155 ----------------------------MQSWVARVVGVTLAALFAVLTG
.
MMAR_0872|M.marinum_M ALLTGCS-GRDAVVQGGTFEFVSPGGKTDIFYDPPASRGHPGPLSGPDLI
MUL_0625|M.ulcerans_Agy99 ALLTGCS-GRDAVVQGGTFEFVSPGGKTDIFYDPPASRGHPGPLSGPDLI
Mb0539|M.bovis_AF2122/97 LLLTGCS-GRDAVAQGGTFEFVSPGGKTDIFYDPPASRGRPGPLSGPELA
Rv0526|M.tuberculosis_H37Rv LLLTGCS-GRDAVAQGGTFEFVSPGGKTDIFYDPPASRGRPGPLSGPELA
MLBr_02412|M.leprae_Br4923 TLLAGCS-GRDAVVQGGTFEFVSPDGKTDIFYEPPASRGRPGPLSGLDLA
MAV_4619|M.avium_104 GLLTGCSSGHDAVAQGGTFEFVSPGGKTDIYYDPPSSRGRPGPLSGPDLA
MAB_3976c|M.abscessus_ATCC_199 LFITACSTGDDAVARGGQFQFVSPGGKTDILYDPPQSRQTPGPISGPSLL
Mflv_2812|M.gilvum_PYR-GCK AAVSGCSSGDDAVAQGGTFEFVSPGGQVDIFYDPPQSRGRPGLIRGPDLM
Mvan_3710|M.vanbaalenii_PYR-1 AAVSGCSSGDDAVAQGGTFEFISPGGQVDIFYDPPQSRGRPGPIRGPDLM
TH_2251|M.thermoresistible__bu -VLTGCSTGDDAVAQGGTFEFVAPGGQTDIFYDPPADRGRPGPISGPDLM
MSMEG_0971|M.smegmatis_MC2_155 -ALAGCSTGDDAVAQGGTFEFVAPGGKTDIFYDPPQSRGRPGTLAGPLLT
::.** * ***.:** *:*::*.*:.** *:** .* ** : * *
MMAR_0872|M.marinum_M DPDRTLSLDD--FAGRVVVVNVWGQWCGPCRAEITQLQQVYDATRAAGVS
MUL_0625|M.ulcerans_Agy99 DPDRTLSLDD--FAGRVVVVNVWGQWCGPCRAEITQLQQVYDETRAAGVS
Mb0539|M.bovis_AF2122/97 DPARSVSLDD--FPGQVVVVNVWGQWCGPCRAEVSQLQRVYDATRGAGVS
Rv0526|M.tuberculosis_H37Rv DPARSVSLDD--FPGQVVVVNVWGQWCGPCRAEVSQLQRVYDATRGAGVS
MLBr_02412|M.leprae_Br4923 DPERTVALDD--FTGNVVVINVWGQWCGPCRTEVTQLQQVYNATRDSGVS
MAV_4619|M.avium_104 DPAHTLSLDDPIFAGRVVVINIWGQWCGPCRSEVSQLQQVYDATRGAGAS
MAB_3976c|M.abscessus_ATCC_199 DPTKTLSLSD--FRGRVVVINVWGQWCGPCRSEFSALEDVYRATHAQGVE
Mflv_2812|M.gilvum_PYR-GCK YPNRTLSLDD--FAEQVVVINVWGQWCGPCRTEMPELQRVYDATRDEGVA
Mvan_3710|M.vanbaalenii_PYR-1 DPNRTLSLDD--FAEQVVVINVWGQWCGPCRTEMPELQRVYDATRNEGVA
TH_2251|M.thermoresistible__bu NPDETISLDD--FAGQVVVINIWGQWCGPCRTEILELQQVYDATRHQGVA
MSMEG_0971|M.smegmatis_MC2_155 DPSKTISLDD--FAGEVVVVNVWGQWCGPCRAEITQLQEVHNATKDKGVA
* .:::*.* * .***:*:*********:*. *: *: *: *.
MMAR_0872|M.marinum_M FLGIDVRDNSRAAAQDFVRDRHVTFPSIYDPAMRTLIAFGGKYPTTVIPS
MUL_0625|M.ulcerans_Agy99 FLGIDVRDNSRAAAQDFVRDRHVTFPSIYDPAMRTLIAFGGKYPTTVIPS
Mb0539|M.bovis_AF2122/97 FLGIDVRDNNRQAPQDFINDRHVTYPSIYDPAMRTLIAFGGKYPTSVIPS
Rv0526|M.tuberculosis_H37Rv FLGIDVRDNNRQAPQDFINDRHVTYPSIYDPAMRTLIAFGGKYPTSVIPS
MLBr_02412|M.leprae_Br4923 FLGIDVRDNNRQAAQDFVNDRQVTFPSIYDPAMRTLIAFGDKYPTTVIPF
MAV_4619|M.avium_104 FLGIDVRDNNRQAALDFVNDRHVTFPSIYDPAMRTLIAFGGKYPTTVIPS
MAB_3976c|M.abscessus_ATCC_199 FLGINVRDNEITKAQDFVTDRKVPYPSIYDPSMRTLIAFGKKFPTGAIPA
Mflv_2812|M.gilvum_PYR-GCK FLGIDVRDNNRQAAVDFIVDRKVTFPSIYDPPMRTMIALGARYPTTVIPS
Mvan_3710|M.vanbaalenii_PYR-1 FLGIDVRDNNRQAAVDFIVDRNVTFPSIYDPPMRTMIALGARYPTTVIPS
TH_2251|M.thermoresistible__bu FLGIDVRDNNIDAAQDFIADRNITFPSIYDPPMRTMIAFGGRYPTTVIPS
MSMEG_0971|M.smegmatis_MC2_155 FLGIDVRDNNRDAAVDFVKDRNVTFPSIYDPPMRTMIAFGGKYPTTVIPS
****:****. . **: **::.:******.***:**:* ::** .**
MMAR_0872|M.marinum_M TLVLDRQHRVAAVFLRELLAEDLQPVVQRLAQEPAAGSTPPGPQ----
MUL_0625|M.ulcerans_Agy99 TLVLDRQHRVAAVFLRELLAEDLQPVVQRLAQEPAAGSTPPGPQ----
Mb0539|M.bovis_AF2122/97 TLVLDRQHRVAAVFLRELLAADLQPVVERVAEEEPSGRAPVGAQ----
Rv0526|M.tuberculosis_H37Rv TLVLDRQHRVAAVFLRELLAADLQPVVERVAEEEPSGRAPVGAQ----
MLBr_02412|M.leprae_Br4923 TLVLDRQHRVAAVFLRELLAGDLQPVVARVAHETVAGQLPRGTS----
MAV_4619|M.avium_104 TLVLDRQHRVAAVFLRELLATDLQPVVQRVAQQ---------------
MAB_3976c|M.abscessus_ATCC_199 TLVLDRQHRVAAVFLRELLAQDLRPVVERLAQESAKETAGEVK-----
Mflv_2812|M.gilvum_PYR-GCK TIVLDRSHRVAAVFLRALLAEDLEPVVRRLAAETTTGSGPPR------
Mvan_3710|M.vanbaalenii_PYR-1 TIVLDRSHRVAAVFLRALLAEDLEPVVRRLAAETATG-----------
TH_2251|M.thermoresistible__bu TVVLDREHRVAAVFLRELLAEDLQPVVERLAAEDPAPDGDAS------
MSMEG_0971|M.smegmatis_MC2_155 TVVLDRQHRVAAVFLRELLAEDLEPLIERLLAEPAEPGEPAVSKEQRP
*:****.********* *** **.*:: *: :