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GIERWRRRRPPTRWLLVIRRGIAAGLSAVLFGAAVSGCSSGDDAVAQGGTFEFISPGGQVDIFYDPPQSR GRPGPIRGPDLMDPNRTLSLDDFAEQVVVINVWGQWCGPCRTEMPELQRVYDATRNEGVAFLGIDVRDNN RQAAVDFIVDRNVTFPSIYDPPMRTMIALGARYPTTVIPSTIVLDRSHRVAAVFLRALLAEDLEPVVRRL AAETATG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3710 | - | - | 100% (218) | redoxin domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_0866 | - | 5e-84 | 72.36% (199) | redoxin domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_3240 | - | 3e-65 | 59.18% (196) | redoxin domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0539 | - | 2e-80 | 70.94% (203) | thioredoxin protein |
M. gilvum PYR-GCK | Mflv_2812 | - | 1e-116 | 92.66% (218) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal |
M. tuberculosis H37Rv | Rv0526 | - | 2e-80 | 70.94% (203) | thioredoxin protein |
M. leprae Br4923 | MLBr_02412 | - | 1e-77 | 70.68% (191) | hypothetical protein MLBr_02412 |
M. abscessus ATCC 19977 | MAB_3976c | - | 3e-70 | 63.13% (198) | thioredoxin |
M. marinum M | MMAR_0872 | - | 6e-82 | 73.44% (192) | thioredoxin protein (thiol-disulfide interchange protein) |
M. avium 104 | MAV_4619 | - | 2e-80 | 72.68% (194) | hypothetical protein MAV_4619 |
M. smegmatis MC2 155 | MSMEG_0971 | - | 3e-85 | 72.77% (202) | hypothetical protein MSMEG_0971 |
M. thermoresistible (build 8) | TH_2251 | - | 1e-87 | 79.06% (191) | POSSIBLE THIOREDOXIN PROTEIN (THIOL-DISULFIDE INTERCHANGE |
M. ulcerans Agy99 | MUL_0625 | - | 2e-81 | 72.92% (192) | thioredoxin protein (thiol-disulfide interchange protein) |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0872|M.marinum_M --------------------------------------MRRLVIAAAVLA MUL_0625|M.ulcerans_Agy99 ------------------------------------MTMRRLVIAAAVLA Mb0539|M.bovis_AF2122/97 -------------------------MQSRATRRSGALTMRRLVIAAAVSA Rv0526|M.tuberculosis_H37Rv -------------------------MQSRATRRSGALTMRRLVIAAAVSA MLBr_02412|M.leprae_Br4923 -------------------MIAPATMQSEAMRRSGATIIWRLANAGALLA MAV_4619|M.avium_104 ------------------------------------MSARVLAMAGAVLA MAB_3976c|M.abscessus_ATCC_199 --------------------------------------MRLLVAALAALA Mvan_3710|M.vanbaalenii_PYR-1 -----------------MGIERWRRRRPPTRWLLVIRRGIAAGLSAVLFG Mflv_2812|M.gilvum_PYR-GCK MTRRLTDAPRMSPSRLDVGVERRRRMRPPIHWSLVVRRGIVAGLSAVLLG TH_2251|M.thermoresistible__bu -----------------------------------VKRLVVLLVGTAML- MSMEG_0971|M.smegmatis_MC2_155 ----------------------------MQSWVARVVGVTLAALFAVLTG . MMAR_0872|M.marinum_M ALLTGCS-GRDAVVQGGTFEFVSPGGKTDIFYDPPASRGHPGPLSGPDLI MUL_0625|M.ulcerans_Agy99 ALLTGCS-GRDAVVQGGTFEFVSPGGKTDIFYDPPASRGHPGPLSGPDLI Mb0539|M.bovis_AF2122/97 LLLTGCS-GRDAVAQGGTFEFVSPGGKTDIFYDPPASRGRPGPLSGPELA Rv0526|M.tuberculosis_H37Rv LLLTGCS-GRDAVAQGGTFEFVSPGGKTDIFYDPPASRGRPGPLSGPELA MLBr_02412|M.leprae_Br4923 TLLAGCS-GRDAVVQGGTFEFVSPDGKTDIFYEPPASRGRPGPLSGLDLA MAV_4619|M.avium_104 GLLTGCSSGHDAVAQGGTFEFVSPGGKTDIYYDPPSSRGRPGPLSGPDLA MAB_3976c|M.abscessus_ATCC_199 LFITACSTGDDAVARGGQFQFVSPGGKTDILYDPPQSRQTPGPISGPSLL Mvan_3710|M.vanbaalenii_PYR-1 AAVSGCSSGDDAVAQGGTFEFISPGGQVDIFYDPPQSRGRPGPIRGPDLM Mflv_2812|M.gilvum_PYR-GCK AAVSGCSSGDDAVAQGGTFEFVSPGGQVDIFYDPPQSRGRPGLIRGPDLM TH_2251|M.thermoresistible__bu -VLTGCSTGDDAVAQGGTFEFVAPGGQTDIFYDPPADRGRPGPISGPDLM MSMEG_0971|M.smegmatis_MC2_155 -ALAGCSTGDDAVAQGGTFEFVAPGGKTDIFYDPPQSRGRPGTLAGPLLT ::.** * ***.:** *:*::*.*:.** *:** .* ** : * * MMAR_0872|M.marinum_M DPDRTLSLDD--FAGRVVVVNVWGQWCGPCRAEITQLQQVYDATRAAGVS MUL_0625|M.ulcerans_Agy99 DPDRTLSLDD--FAGRVVVVNVWGQWCGPCRAEITQLQQVYDETRAAGVS Mb0539|M.bovis_AF2122/97 DPARSVSLDD--FPGQVVVVNVWGQWCGPCRAEVSQLQRVYDATRGAGVS Rv0526|M.tuberculosis_H37Rv DPARSVSLDD--FPGQVVVVNVWGQWCGPCRAEVSQLQRVYDATRGAGVS MLBr_02412|M.leprae_Br4923 DPERTVALDD--FTGNVVVINVWGQWCGPCRTEVTQLQQVYNATRDSGVS MAV_4619|M.avium_104 DPAHTLSLDDPIFAGRVVVINIWGQWCGPCRSEVSQLQQVYDATRGAGAS MAB_3976c|M.abscessus_ATCC_199 DPTKTLSLSD--FRGRVVVINVWGQWCGPCRSEFSALEDVYRATHAQGVE Mvan_3710|M.vanbaalenii_PYR-1 DPNRTLSLDD--FAEQVVVINVWGQWCGPCRTEMPELQRVYDATRNEGVA Mflv_2812|M.gilvum_PYR-GCK YPNRTLSLDD--FAEQVVVINVWGQWCGPCRTEMPELQRVYDATRDEGVA TH_2251|M.thermoresistible__bu NPDETISLDD--FAGQVVVINIWGQWCGPCRTEILELQQVYDATRHQGVA MSMEG_0971|M.smegmatis_MC2_155 DPSKTISLDD--FAGEVVVVNVWGQWCGPCRAEITQLQEVHNATKDKGVA * .:::*.* * .***:*:*********:*. *: *: *: *. MMAR_0872|M.marinum_M FLGIDVRDNSRAAAQDFVRDRHVTFPSIYDPAMRTLIAFGGKYPTTVIPS MUL_0625|M.ulcerans_Agy99 FLGIDVRDNSRAAAQDFVRDRHVTFPSIYDPAMRTLIAFGGKYPTTVIPS Mb0539|M.bovis_AF2122/97 FLGIDVRDNNRQAPQDFINDRHVTYPSIYDPAMRTLIAFGGKYPTSVIPS Rv0526|M.tuberculosis_H37Rv FLGIDVRDNNRQAPQDFINDRHVTYPSIYDPAMRTLIAFGGKYPTSVIPS MLBr_02412|M.leprae_Br4923 FLGIDVRDNNRQAAQDFVNDRQVTFPSIYDPAMRTLIAFGDKYPTTVIPF MAV_4619|M.avium_104 FLGIDVRDNNRQAALDFVNDRHVTFPSIYDPAMRTLIAFGGKYPTTVIPS MAB_3976c|M.abscessus_ATCC_199 FLGINVRDNEITKAQDFVTDRKVPYPSIYDPSMRTLIAFGKKFPTGAIPA Mvan_3710|M.vanbaalenii_PYR-1 FLGIDVRDNNRQAAVDFIVDRNVTFPSIYDPPMRTMIALGARYPTTVIPS Mflv_2812|M.gilvum_PYR-GCK FLGIDVRDNNRQAAVDFIVDRKVTFPSIYDPPMRTMIALGARYPTTVIPS TH_2251|M.thermoresistible__bu FLGIDVRDNNIDAAQDFIADRNITFPSIYDPPMRTMIAFGGRYPTTVIPS MSMEG_0971|M.smegmatis_MC2_155 FLGIDVRDNNRDAAVDFVKDRNVTFPSIYDPPMRTMIAFGGKYPTTVIPS ****:****. . **: **::.:******.***:**:* ::** .** MMAR_0872|M.marinum_M TLVLDRQHRVAAVFLRELLAEDLQPVVQRLAQEPAAGSTPPGPQ---- MUL_0625|M.ulcerans_Agy99 TLVLDRQHRVAAVFLRELLAEDLQPVVQRLAQEPAAGSTPPGPQ---- Mb0539|M.bovis_AF2122/97 TLVLDRQHRVAAVFLRELLAADLQPVVERVAEEEPSGRAPVGAQ---- Rv0526|M.tuberculosis_H37Rv TLVLDRQHRVAAVFLRELLAADLQPVVERVAEEEPSGRAPVGAQ---- MLBr_02412|M.leprae_Br4923 TLVLDRQHRVAAVFLRELLAGDLQPVVARVAHETVAGQLPRGTS---- MAV_4619|M.avium_104 TLVLDRQHRVAAVFLRELLATDLQPVVQRVAQQ--------------- MAB_3976c|M.abscessus_ATCC_199 TLVLDRQHRVAAVFLRELLAQDLRPVVERLAQESAKETAGEVK----- Mvan_3710|M.vanbaalenii_PYR-1 TIVLDRSHRVAAVFLRALLAEDLEPVVRRLAAETATG----------- Mflv_2812|M.gilvum_PYR-GCK TIVLDRSHRVAAVFLRALLAEDLEPVVRRLAAETTTGSGPPR------ TH_2251|M.thermoresistible__bu TVVLDREHRVAAVFLRELLAEDLQPVVERLAAEDPAPDGDAS------ MSMEG_0971|M.smegmatis_MC2_155 TVVLDRQHRVAAVFLRELLAEDLEPLIERLLAEPAEPGEPAVSKEQRP *:****.********* *** **.*:: *: :