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VGSCSDSRVPDGSRLGLYSGIVLAGIGMGMVVGQGVAVASPGDSTGAAASASPSSSDAADKPAADKPDTD TDAETDADAAEEVADDDESQEADEAADERTSRKPSSRIAEDQSEDTASEDTASEDAASEDAASEDAASED AASDEDVAVASTVAEPANAAITQNAAITDREVARTVRSIVSARPVTAEAIVTDVLTWIGLRPSVDDSPAP QTPVSTLVEGLWLAVRQNQYTWNNQRPVADVSIDGPGPDGAVTGSLNAVDFDDTALTYRLTAGPVYGRVR IDADGRFTYTPGAAAAGRADTFTIRVDDTSGNPFRVHGLLGLLGITRPTEVTIAIPANPSAPQSVSPITV ASDSGTPGRVIDGRVTDHIVVNTADAAAVLNALSSALGAPAGFADEAMVIRTTAGTGDSAEHFYRFAETV GGVPVVGSEVILVTNADGDVTSVVNYYRGLGDGFDVTPDTSVDDDDELRWIAGTAYVGSGADPAAIESFI AASRFSKELLVHSSTDDASPRLAWRVVVHVPDTGEMAPSGMTYLIDADGEQAGEVIIAVSNAQAAAATTT AKDWLGATRAITVETRRIWFFTTNEMADSSRMIATYTTSYGFFGLGAPVLPGKVVKKGWFSWDKAAVSAH ANHAVAYDYFYDVLGRRSYDNAGAPVIVSIKYRPDSYPLGYANAMWDPTIRQFAYGDKGYFQAALDIVAH EYAHAVVTSMVGNGDPVWESGESGALNEAYADVFGLLIEGKSGADRWLIAEDSDNGTIRDLANPRSITTS YGPHRDRYSTRYTGKGDDGGEHVNSTIFSHAAYLMMTDPATADVSDDTWAKVFYHSLERLGATAMFSDGR AALLDAALSQGLTYAQRLAIAEAFDTVEIYGAAPSQTIAV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_2748 | - | - | 100% (880) | Zinc metalloprotease (elastase)-like protein |
M. gilvum PYR-GCK | Mflv_0863 | - | 7e-25 | 31.93% (332) | hypothetical protein Mflv_0863 |
M. gilvum PYR-GCK | Mflv_1722 | - | 3e-23 | 30.08% (379) | glycoside hydrolase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2471c | rne | 4e-06 | 34.91% (106) | ribonuclease E |
M. tuberculosis H37Rv | Rv2444c | rne | 4e-06 | 34.91% (106) | ribonuclease E |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1849 | - | 1e-15 | 30.22% (278) | putative metalloprotease |
M. marinum M | MMAR_3768 | rne | 8e-07 | 28.45% (116) | ribonuclease E Rne |
M. avium 104 | MAV_3172 | - | 6e-06 | 30.36% (112) | prolipoprotein diacylglyceryl transferase |
M. smegmatis MC2 155 | MSMEG_0055 | - | 3e-07 | 27.59% (174) | hypothetical protein MSMEG_0055 |
M. thermoresistible (build 8) | TH_2316 | - | 4e-06 | 22.96% (196) | conserved hypothetical protein |
M. ulcerans Agy99 | MUL_3715 | rne | 1e-06 | 26.32% (114) | ribonuclease E Rne |
M. vanbaalenii PYR-1 | Mvan_3789 | - | 0.0 | 58.44% (912) | peptidase M4, thermolysin |
CLUSTAL 2.0.9 multiple sequence alignment Mb2471c|M.bovis_AF2122/97 MIDGAPPSDPP-EPSQHEELPDRLRVHSLARTLGTTSRRVLDALTALDGR Rv2444c|M.tuberculosis_H37Rv MIDGAPPSDPP-EPSQHEELPDRLRVHSLARTLGTTSRRVLDALTALDGR MMAR_3768|M.marinum_M MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR MUL_3715|M.ulcerans_Agy99 MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR Mflv_2748|M.gilvum_PYR-GCK -MGSCSDSRVP--------DGSRLGLYSGIVLAGIGMGMVVGQGVAVASP Mvan_3789|M.vanbaalenii_PYR-1 -MDQCPRSRTP--------NGSWRGLYSGVVLAGIGVGMVVGQGVAVASP MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- Mb2471c|M.bovis_AF2122/97 VRSAHSTVDRVDAVRVRDLLATHLETAG-----------VLAASVHAPEA Rv2444c|M.tuberculosis_H37Rv VRSAHSTVDRVDAVRVRDLLATHLETAG-----------VLAASVHAPEA MMAR_3768|M.marinum_M IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEGQQAPDAVAAEVPDAPGE MUL_3715|M.ulcerans_Agy99 IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE Mflv_2748|M.gilvum_PYR-GCK GDS--------TGAAASASPSSSDAADK------------PAADKPDTDT Mvan_3789|M.vanbaalenii_PYR-1 SEASEPSSSSQSGDTADAGPSTASQTPT------------TADADPEAEA MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- Mb2471c|M.bovis_AF2122/97 SEEP---ESRLMLETQETR---NADVERPHYMPLFVAPQPIPEPLADDED Rv2444c|M.tuberculosis_H37Rv SEEP---ESRLMLETQETR---NADVERPHYMPLFVAPQPIPEPLADDED MMAR_3768|M.marinum_M PAEPDEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDA MUL_3715|M.ulcerans_Agy99 PAEP---ESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDA Mflv_2748|M.gilvum_PYR-GCK DAET---DADAAEEVADD-----DESQEADEAADERTSRKPSSRIAEDQS Mvan_3789|M.vanbaalenii_PYR-1 EAEP---DPDPGPDAEPDLADVADEAEEADDIEVAASTDEDPTRQSRTRT MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu ---------------------VGRVGALAVALGVGVAVATGGTAVAWADS Mb2471c|M.bovis_AF2122/97 VDDGPDYVADDSDADDEGQLDRPANRRRRRGRRGRGRGRGEQGGSDGDPV Rv2444c|M.tuberculosis_H37Rv VDDGPDYVADDSDADDEGQLDRPANRRRRRGRRGRGRGRGEQGGSDGDPV MMAR_3768|M.marinum_M DDE-----SGDEGDDDEEQADRPANRRRRRGRRGRGRGRGEQGANDGQDQ MUL_3715|M.ulcerans_Agy99 DDE-----SGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQ Mflv_2748|M.gilvum_PYR-GCK EDTA----SEDTASEDAASEDAASEDAASEDAASDEDVAVASTVAEPAN- Mvan_3789|M.vanbaalenii_PYR-1 EEAP----SADADDADAADAAAAADGEADADAAEDGEAALATSVADTPDP MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu GSTASSSSSQDSSSKSNPAQTRSSAKSGIGSGAGSGPGSRLDRPASRAPL Mb2471c|M.bovis_AF2122/97 DQQSEPRAQQFTSADAAETDDGDDRDSEDTEAGDNGEDENGSLEAGNRRR Rv2444c|M.tuberculosis_H37Rv DQQSEPRAQQFTSADAAETDDGDDRDSEDTEAGDNGEDENGSLEAGNRRR MMAR_3768|M.marinum_M PGDDGDEAPQKTGGNSTSSDDTEAQDGADSEESDNGDDDNGSADGANRRR MUL_3715|M.ulcerans_Agy99 PGDDGDEAPQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASRRR Mflv_2748|M.gilvum_PYR-GCK ----AAITQNAAITDREVA--RTVRSIVSARPVTAEAIVTDVLTWIGLRP Mvan_3789|M.vanbaalenii_PYR-1 AAAVAVVSAGPALPDVATAPAAALRTLVSARPVTVQNMVTDVLTWVGLRP MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu GGSGADSSATEQTGAVSSGTSAWRSAGMPAGTSLTGRLADSVRDAVKPWR Mb2471c|M.bovis_AF2122/97 RRRRRRKSASGDDNDAALEGPLPDDPPNTVVHERVPRAGDKAGNSQDGG- Rv2444c|M.tuberculosis_H37Rv RRRRRRKSASGDDNDAALEGPLPDDPPNTVVHERVPRAGDKAGNSQDGG- MMAR_3768|M.marinum_M RRRRRRKSGAGDDGD---EGPAPDDPPNTVVHERAPRSGGKSGNSDSGDD MUL_3715|M.ulcerans_Agy99 RRRRRRKSGAGDDGD---EGPAPDDPPNTVVHERAPRSGDKSGNSDSGDD Mflv_2748|M.gilvum_PYR-GCK SVDDSPAPQTPVSTLVEGLWLAVRQNQYTWNNQRPVADVSIDGPGPDGAV Mvan_3789|M.vanbaalenii_PYR-1 QADDGPTPPTPVSALVQSLWLAVRQTQYTWNNQRPTADATTSGPGLDGVV MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu PATTRSTDPTPVETPAEANPEAQPDAHAGSPGE-STAPETQPAPSSRGIR Mb2471c|M.bovis_AF2122/97 SGSTEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVER Rv2444c|M.tuberculosis_H37Rv SGSTEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVER MMAR_3768|M.marinum_M SGGNEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVER MUL_3715|M.ulcerans_Agy99 SGGNEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVER Mflv_2748|M.gilvum_PYR-GCK TGSLNAVDFDDT----ALTYRLTAGPVYGRVRIDADGRFTYTPGAAAAGR Mvan_3789|M.vanbaalenii_PYR-1 TGNLNAVDYDDS----ALTFTLTGGPAYGRVTIDASGGFTYTPGAAAAGR MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 -------------------------------------------MGVLSDV MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu SMTAVLPDTESTNTESTNTESTVQHDDSERRSSLRSTAASVPELSTPVRL Mb2471c|M.bovis_AF2122/97 VMVVRDRVRTEPPLPGTRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLG Rv2444c|M.tuberculosis_H37Rv VMVVRDRVRTEPPLPGTRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLG MMAR_3768|M.marinum_M VMVVRDRVRTEPPHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLG MUL_3715|M.ulcerans_Agy99 VMVVRDRVRTEPPHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLG Mflv_2748|M.gilvum_PYR-GCK ADTFTIRVDDTSGNPFRVHGLLGLLGITRPTEVTIAIPANPSAPQSVSP- Mvan_3789|M.vanbaalenii_PYR-1 ADKFTVRIDDTSGNPFHVHGLLGLLGITRPTEVTVVIAASSPVLQSVPSG MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 ADFGKDVIDDRDKWADRFKKVGHFIERNAKGDRLERVAKFGRALGDFSGK MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu ADATAVRALAERLTERRSVTLESVRAFTDVAATTALTSAASVAAATVEPV Mb2471c|M.bovis_AF2122/97 IVQNVLPSMEAAFVDIGR-GRNGVLYAGEVNWDAAGLGGADRKIEQALKP Rv2444c|M.tuberculosis_H37Rv IVQNVLPSMEAAFVDIGR-GRNGVLYAGEVNWDAAGLGGADRKIEQALKP MMAR_3768|M.marinum_M IVQNVLPSMEAAFVDIGR-GRNGVLYAGEVNWDAAGLGGADRKIEQALKP MUL_3715|M.ulcerans_Agy99 IVQNVLPSMEAAFVDIGR-GRNGVLYAGEVNWDAAGLGGADRKIEQALKP Mflv_2748|M.gilvum_PYR-GCK ITVASDSG------TPGR-----VIDGRVTDHIVVNTADAAAVLNALSSA Mvan_3789|M.vanbaalenii_PYR-1 LTMSELTSRDGVEVTPGRNGAVGVIDGRLTDQLVVNADDAAAVLNSLAFA MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 FTDFFESNLGKRMVKAAR-------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- TH_2316|M.thermoresistible__bu ALITAAPEATPAVDAEQP-------------------------------- Mb2471c|M.bovis_AF2122/97 GDYVVVQVSKDPVGHKGARLTTQVSLAGRFLVYVPGASSTGISRKLPDTE Rv2444c|M.tuberculosis_H37Rv GDYVVVQVSKDPVGHKGARLTTQVSLAGRFLVYVPGASSTGISRKLPDTE MMAR_3768|M.marinum_M GDYIVVQVSKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTE MUL_3715|M.ulcerans_Agy99 GDYIVVQVSKDPVGHKGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTE Mflv_2748|M.gilvum_PYR-GCK LGAPAGFADEAMVIRTTAGTGDSAEHFYRFAETVGGVPVVGSEVILVTNA Mvan_3789|M.vanbaalenii_PYR-1 LGAVTGFAEPSAITATSVGKGADAEHFYRYTEKIAGVPVLGSEVILVTNA MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 -SPILAAGQHVITGMKLTTGVGDPENGRRFGEGADHMSAAGRTLDSAYPT MAV_3172|M.avium_104 ---MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAGIVAALLIGDRRWEA TH_2316|M.thermoresistible__bu --AAPRLVTGLLAAVGLAPFTANSPLAPTQSTPLLALLGWARRETDRAYT Mb2471c|M.bovis_AF2122/97 RQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVARLRERWEQIEAKA Rv2444c|M.tuberculosis_H37Rv RQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVARLRERWEQIEAKA MMAR_3768|M.marinum_M RQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKA MUL_3715|M.ulcerans_Agy99 RQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKA Mflv_2748|M.gilvum_PYR-GCK DGDVTSVVNYYRGLGDGFDVTPDTSVDDDDELRWIAG------TAYVGSG Mvan_3789|M.vanbaalenii_PYR-1 AGEVTSVFNYYRGLGEGFGITPDAAVDEDSEVWSIAG------TAYLGPD MAB_1849|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 SDWDSAASDAYLSQNNGQVTR----------------------------- MAV_3172|M.avium_104 RGGERGVIYDIALWT----------------------------------- TH_2316|M.thermoresistible__bu QQARSLVTARPAVVSTAAVVDP---------------------------- Mb2471c|M.bovis_AF2122/97 QETKEKAAGAAVALYEEPDVLVKVIRDLFNEDFVGLIVSGDEAWNTINEY Rv2444c|M.tuberculosis_H37Rv QETKEKAAGAAVALYEEPDVLVKVIRDLFNEDFVGLIVSGDEAWNTINEY MMAR_3768|M.marinum_M VEIKQKAAGAAVALYEEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEY MUL_3715|M.ulcerans_Agy99 VEIKQKAAGAAVALYEEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEY Mflv_2748|M.gilvum_PYR-GCK ADPAAIESFIAASRFSKELLVHSSTDDASPRLAWRVVVHVPDTGEMAPSG Mvan_3789|M.vanbaalenii_PYR-1 VDPRVLESFLSTTTFTRELVVYT-HDDTTSDLAWRVVVVVPDTGEMSPSG MAB_1849|M.abscessus_ATCC_1997 -------------------------------MCQRFIIP--------PAV MSMEG_0055|M.smegmatis_MC2_155 ----------AEALVHADQVVAAVLSREAEQIATTREVLDSEADWLGDMS MAV_3172|M.avium_104 -------------------VPFGLVGGRLYHLATDWRTYWGPGGAGFGAA TH_2316|M.thermoresistible__bu ---------LPADLIGETERIGRITGPGITDGPNRLNIYGTDLGIMWDMG Mb2471c|M.bovis_AF2122/97 VNSVAPELVSKLTKYESADGPDGQSAPDVFTVHRIDEQLAKAMDRKVWLP Rv2444c|M.tuberculosis_H37Rv VNSVAPELVSKLTKYESADGPDGQSAPDVFTVHRIDEQLAKAMDRKVWLP MMAR_3768|M.marinum_M VSSVAPDLVSKLSKYEPAVGSEGQVGPDVFAVHRIDEQLAKAMDRKVWLP MUL_3715|M.ulcerans_Agy99 VSSVAPDLVSKLSKYEPAVGSEGQVGPDVFAVHRIDEHLAKAMDRKVWLP Mflv_2748|M.gilvum_PYR-GCK MTYLIDADGEQAGEVIIAVSNAQAAAATTTAKDWLGATRAITVETRRIWF Mvan_3789|M.vanbaalenii_PYR-1 ATYVIDADGASAGDVILGTSNAQAATSISIAKDWLGESRVMTIETRTVLW MAB_1849|M.abscessus_ATCC_1997 LSRLAED-----GDIAEDSRAALSATAACELSWRTLRNAHTRATQASLLT MSMEG_0055|M.smegmatis_MC2_155 LVTMATGLIPYVGRAAQTAAEIAMVTKAVGASTDQFMMMRDKADENAAEV MAV_3172|M.avium_104 VRIWDGGLGIWGAVALGAVGAWIGCRRHGIPLPAFADALAPGIILAQAIG TH_2316|M.thermoresistible__bu EWRGQRAVHVVFGDTFSGPNMSGDWISNAIMISTSRTLYENPAGFLEQTG Mb2471c|M.bovis_AF2122/97 SGGTLVIDRTEAMTVIDVNTGKFTGAGGNLEQTVTKNNLEAAEEIVRQLR Rv2444c|M.tuberculosis_H37Rv SGGTLVIDRTEAMTVIDVNTGKFTGAGGNLEQTVTKNNLEAAEEIVRQLR MMAR_3768|M.marinum_M SGGTLVIDRTEAMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLR MUL_3715|M.ulcerans_Agy99 SGGTLVIDRTEAMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLR Mflv_2748|M.gilvum_PYR-GCK FTTNEMADSSRMIATYTTSYGFFGLGAPVLPGKVVKKGWFSWDKAAVSAH Mvan_3789|M.vanbaalenii_PYR-1 FRTYQLIDAPRNITTYRTSYSFFGLGSPSLPGTVVKRGFFGWDAAAVSAH MAB_1849|M.abscessus_ATCC_1997 SRAAALGAAATGLAKVPETPVFDCRQTTSLPGVAVADPATSKDATAQRAF MSMEG_0055|M.smegmatis_MC2_155 RDAIGKYEAVAG-DADDTTADDTAGDAPESEPTAAEDSSETSKEDGQSRH MAV_3172|M.avium_104 RLGNYFNQELYG-RETTLPWGLEIFYRRDPSGYIDPHSLDGVSTGQVALV TH_2316|M.thermoresistible__bu PAFQFIPGGQLLSWFFPAEVTVIPTAGVHANGTQYVNYMSVRQWGVPGSW . Mb2471c|M.bovis_AF2122/97 LRDIGGIVVIDFIDMVLESNRDLVLRRLTESLARDRTRHQVSEVTSLGLV Rv2444c|M.tuberculosis_H37Rv LRDIGGIVVIDFIDMVLESNRDLVLRRLTESLARDRTRHQVSEVTSLGLV MMAR_3768|M.marinum_M LRDIGGIVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLV MUL_3715|M.ulcerans_Agy99 LRDIGGIVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLV Mflv_2748|M.gilvum_PYR-GCK AN--HAVAYDYFYDVLGRRSYDNAGAPVIVSIKYRPDSYPLGYAN--AMW Mvan_3789|M.vanbaalenii_PYR-1 AN--MAVVYDYFQDVLGRTSFDDEGALVSVSIRYNPRTSTVGYAN--AFW MAB_1849|M.abscessus_ATCC_1997 DET--VAVAEFYRNCFGRNSVDNAGMTLVSSIHYG-----VKYSN--AFW MSMEG_0055|M.smegmatis_MC2_155 EN----PVAAPSGGGGGATSGGGGGAPSSASSAGPAGTPQVPSPPGFGAA MAV_3172|M.avium_104 VQP--TFLYELLWNLLIFVALLYADRRLTLGHGRLFALYVAGYCVGRFCV TH_2316|M.thermoresistible__bu TTNFSAISRYDQATDTWVTVPSSVRSAGWLRSSTPYRAGDQNFQQMAYVL Mb2471c|M.bovis_AF2122/97 QLTRKRLGTGLI---EAFSTSCPNCSGRGILLHADPVDSAAATGRKSEPG Rv2444c|M.tuberculosis_H37Rv QLTRKRLGTGLI---EAFSTSCPNCSGRGILLHADPVDSAAATGRKSEPG MMAR_3768|M.marinum_M QLTRKRLGTGLV---EAFSTSCPHCSGRGILLHADPVDSAPTTGRKADSG MUL_3715|M.ulcerans_Agy99 QLTRKRLGTGLI---EAFSTSCPHCSGRGILLHADPVDSAPTTGRKADSG Mflv_2748|M.gilvum_PYR-GCK DPTIRQFAYGDK---GYFQAALDIVAHEYAHAVVTSMVGNGDPVWESGES Mvan_3789|M.vanbaalenii_PYR-1 DPSRQLFAFGDA---GYFQASVDVVAHEFTHAVVSYVVGDGGSVLDNGES MAB_1849|M.abscessus_ATCC_1997 NGSQMAYGDGDGQIFLDFTKSNDVIGHELTHGVTQFTAG----LDYENEA MSMEG_0055|M.smegmatis_MC2_155 NTPTDAQPGAAA------ASDAAGMLGSVMGAMLGPLGGIVGGVVQAAGQ MAV_3172|M.avium_104 ELLRDDTATHIAGIRINSFTSTFVFIGAVVYLMAAPKGREDPESLRGNQY TH_2316|M.thermoresistible__bu QPVDQVGEDGVRYVYAFGTPSGRQGSVHLSRVPEEHITDVSKYEYWDGNA : Mb2471c|M.bovis_AF2122/97 ARRGKRSKKSRSEESSDRSMVAKVPVHAPGEHPMFKAMAAGLSSLAGRGD Rv2444c|M.tuberculosis_H37Rv ARRGKRSKKSRSEESSDRSMVAKVPVHAPGEHPMFKAMAAGLSSLAGRGD MMAR_3768|M.marinum_M GRRNRRSKKNRAEEPSEKEAVAKVPTHAPGEHPMFKAMAASSSSEAEHGD MUL_3715|M.ulcerans_Agy99 GRRNRRSKKNRAEEPSEKEAVAKVPTYAPGEHPMFKAMAASSSSEAEHGD Mflv_2748|M.gilvum_PYR-GCK GALNEAYADVFGLLIEGKSGADRWLIAEDSDNGTIRDLANPRSITTSYGP Mvan_3789|M.vanbaalenii_PYR-1 GALNEAYSDIFGVLVEGKTGDGRWLIGEDSDHGVIRNLADPESIRTAYGP MAB_1849|M.abscessus_ATCC_1997 GALNESVSDVFGSMFRQWQGQQ---SADKADWLIGKDILGPRALDKGYTC MSMEG_0055|M.smegmatis_MC2_155 ALQAATQAGAQAAQLAGQAAAAPDVDRADTDEDTDKDPDAEGDKDSDKRD MAV_3172|M.avium_104 VEEEPAEPEPATVAATTEAATEGVAAPADGAEAAGADATAQRPEESAEPD TH_2316|M.thermoresistible__bu WVSSAAHAAPIIGESTRSAGLFGFIIDWANDPNVFGGYLGGLFGAKTGGN Mb2471c|M.bovis_AF2122/97 EESGEPAAELAEQAGDQ---------------------PPTDLDDTAQAD Rv2444c|M.tuberculosis_H37Rv EESGEPAAELAEQAGDQ---------------------PPTDLDDTAQAD MMAR_3768|M.marinum_M GEVEESGEELTAAVDDQTAVQVALDLGQTDETEETDETDETDETDDFDDD MUL_3715|M.ulcerans_Agy99 GEVEESGEELTAAVDDQTAVQVALDLG---ETEESEETDGTDETDDFDDD Mflv_2748|M.gilvum_PYR-GCK HRDRYSTRYTGKGDDGG------------------EHVNSTIFSHAAYLM Mvan_3789|M.vanbaalenii_PYR-1 YRARVSDMYSGEGDDRG------------------EHVNSTVFSHAAYLM MAB_1849|M.abscessus_ATCC_1997 LRDMADPAAAHCLSPQP-------------------------SHYRDYVP MSMEG_0055|M.smegmatis_MC2_155 GEGKEDGTAPRDRESTD-------------------AMGADDDDRNAHPQ MAV_3172|M.avium_104 VEKPESEETEAEAAEEP----------------------ESEETEAAEEP TH_2316|M.thermoresistible__bu VGEMSVQYNEYLGKYVILYG--------------------NGRTNNIEMR Mb2471c|M.bovis_AF2122/97 FEDTEDTDEDED-------ELDADEDLEDLDDED------LDEDLDVEDS Rv2444c|M.tuberculosis_H37Rv FEDTEDTDEDED-------ELDADEDLEDLDDED------LDEDLDVEDS MMAR_3768|M.marinum_M SDDSDDSDEDDDSDETNDTDVDAGEDEDTDDDSDEDSDDDSDEDEDTEDD MUL_3715|M.ulcerans_Agy99 SDDSDDSDEDDDTDETNDTDVDADEDEDTDDDS--------DEDEDTEDD Mflv_2748|M.gilvum_PYR-GCK MTDPATADVSDD-------------------------------------- Mvan_3789|M.vanbaalenii_PYR-1 MTDADTAGVSDE-------------------------------------- MAB_1849|M.abscessus_ATCC_1997 GSDPHEGSGIPN-------------------------------------- MSMEG_0055|M.smegmatis_MC2_155 AGSGTDSAGEDD-------------------------------------- MAV_3172|M.avium_104 GEPEAEEPEEPE-------------------------------------- TH_2316|M.thermoresistible__bu IADSPEGPWSDP-------------------------------------- Mb2471c|M.bovis_AF2122/97 ---------------DSDDEDSDEDAADADVDEEDAAG-------LDGSP Rv2444c|M.tuberculosis_H37Rv ---------------DSDDEDSDEDAADADVDEEDAAG-------LDGSP MMAR_3768|M.marinum_M ELDDDLDEDDLDDDLDEDDDDLDDELDDDDSDSDDEDGES---ELTEPAA MUL_3715|M.ulcerans_Agy99 ---------------DELDDDLDDELDDDDSDSDDEDSES---ELTEPAA Mflv_2748|M.gilvum_PYR-GCK ----------------TWAKVFYHSLERLGATAMFSDGRA---ALLDAAL Mvan_3789|M.vanbaalenii_PYR-1 ----------------TWAKVFYHSLG-LGTSARFVDGRA---AVLSSAG MAB_1849|M.abscessus_ATCC_1997 -------------------HAFYLAATKYGSHSWEAVGTVWYQALTSPKA MSMEG_0055|M.smegmatis_MC2_155 ------------------KKPAMTLPPDLQAASALDTGAG----SAPVHV MAV_3172|M.avium_104 -----------------AEEPEEPETEEPEADSDEEPEEE------SGEA TH_2316|M.thermoresistible__bu ----------------IILATPQQYPGLYAPMIHPWSGTG---YLLDENG Mb2471c|M.bovis_AF2122/97 GE-VDVPGVTELAPTRPRRRVAGRPAGPPIRLD------ Rv2444c|M.tuberculosis_H37Rv GE-VDVPGVTELAPTRPRRRVAGRPAGPPIRLD------ MMAR_3768|M.marinum_M GR-PAALEVTTIAERPRRRRAAGRPAGPPIHLG------ MUL_3715|M.ulcerans_Agy99 GR-PAALEVTTIAERPRRRRAAGRPAGPPIHLG------ Mflv_2748|M.gilvum_PYR-GCK SQGLTYAQRLAIAEAFDTVEIYGAAPSQTIAV------- Mvan_3789|M.vanbaalenii_PYR-1 AQGLTATQLAAIARAFDTVEIYGAAPSSVIAV------- MAB_1849|M.abscessus_ATCC_1997 TKNMTFKAFAKLTRQIAAGRTGADSPQAAIDEAWTEVGL MSMEG_0055|M.smegmatis_MC2_155 GADFEHSQLRTVAAATLDHGIPGSAAARGA--------- MAV_3172|M.avium_104 PEQPVAEEPEPAPQQPETKRRWGARLRDRLSGR------ TH_2316|M.thermoresistible__bu DPDPESLYWNMSMWGPYNVYLMQTDLSSLVEV-------