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M. gilvum PYR-GCK Mflv_2748 (-)

annotation: Zinc metalloprotease (elastase)-like protein
coordinates: 2892310 - 2894952
length: 880

VGSCSDSRVPDGSRLGLYSGIVLAGIGMGMVVGQGVAVASPGDSTGAAASASPSSSDAADKPAADKPDTD
TDAETDADAAEEVADDDESQEADEAADERTSRKPSSRIAEDQSEDTASEDTASEDAASEDAASEDAASED
AASDEDVAVASTVAEPANAAITQNAAITDREVARTVRSIVSARPVTAEAIVTDVLTWIGLRPSVDDSPAP
QTPVSTLVEGLWLAVRQNQYTWNNQRPVADVSIDGPGPDGAVTGSLNAVDFDDTALTYRLTAGPVYGRVR
IDADGRFTYTPGAAAAGRADTFTIRVDDTSGNPFRVHGLLGLLGITRPTEVTIAIPANPSAPQSVSPITV
ASDSGTPGRVIDGRVTDHIVVNTADAAAVLNALSSALGAPAGFADEAMVIRTTAGTGDSAEHFYRFAETV
GGVPVVGSEVILVTNADGDVTSVVNYYRGLGDGFDVTPDTSVDDDDELRWIAGTAYVGSGADPAAIESFI
AASRFSKELLVHSSTDDASPRLAWRVVVHVPDTGEMAPSGMTYLIDADGEQAGEVIIAVSNAQAAAATTT
AKDWLGATRAITVETRRIWFFTTNEMADSSRMIATYTTSYGFFGLGAPVLPGKVVKKGWFSWDKAAVSAH
ANHAVAYDYFYDVLGRRSYDNAGAPVIVSIKYRPDSYPLGYANAMWDPTIRQFAYGDKGYFQAALDIVAH
EYAHAVVTSMVGNGDPVWESGESGALNEAYADVFGLLIEGKSGADRWLIAEDSDNGTIRDLANPRSITTS
YGPHRDRYSTRYTGKGDDGGEHVNSTIFSHAAYLMMTDPATADVSDDTWAKVFYHSLERLGATAMFSDGR
AALLDAALSQGLTYAQRLAIAEAFDTVEIYGAAPSQTIAV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2748--100% (880)Zinc metalloprotease (elastase)-like protein
M. gilvum PYR-GCKMflv_0863-7e-2531.93% (332) hypothetical protein Mflv_0863
M. gilvum PYR-GCKMflv_1722-3e-2330.08% (379) glycoside hydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2471crne4e-0634.91% (106) ribonuclease E
M. tuberculosis H37RvRv2444crne4e-0634.91% (106) ribonuclease E
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1849-1e-1530.22% (278) putative metalloprotease
M. marinum MMMAR_3768rne8e-0728.45% (116) ribonuclease E Rne
M. avium 104MAV_3172-6e-0630.36% (112) prolipoprotein diacylglyceryl transferase
M. smegmatis MC2 155MSMEG_0055-3e-0727.59% (174) hypothetical protein MSMEG_0055
M. thermoresistible (build 8)TH_2316-4e-0622.96% (196) conserved hypothetical protein
M. ulcerans Agy99MUL_3715rne1e-0626.32% (114) ribonuclease E Rne
M. vanbaalenii PYR-1Mvan_3789-0.058.44% (912) peptidase M4, thermolysin

CLUSTAL 2.0.9 multiple sequence alignment


Mb2471c|M.bovis_AF2122/97           MIDGAPPSDPP-EPSQHEELPDRLRVHSLARTLGTTSRRVLDALTALDGR
Rv2444c|M.tuberculosis_H37Rv        MIDGAPPSDPP-EPSQHEELPDRLRVHSLARTLGTTSRRVLDALTALDGR
MMAR_3768|M.marinum_M               MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR
MUL_3715|M.ulcerans_Agy99           MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR
Mflv_2748|M.gilvum_PYR-GCK          -MGSCSDSRVP--------DGSRLGLYSGIVLAGIGMGMVVGQGVAVASP
Mvan_3789|M.vanbaalenii_PYR-1       -MDQCPRSRTP--------NGSWRGLYSGVVLAGIGVGMVVGQGVAVASP
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2471c|M.bovis_AF2122/97           VRSAHSTVDRVDAVRVRDLLATHLETAG-----------VLAASVHAPEA
Rv2444c|M.tuberculosis_H37Rv        VRSAHSTVDRVDAVRVRDLLATHLETAG-----------VLAASVHAPEA
MMAR_3768|M.marinum_M               IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEGQQAPDAVAAEVPDAPGE
MUL_3715|M.ulcerans_Agy99           IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE
Mflv_2748|M.gilvum_PYR-GCK          GDS--------TGAAASASPSSSDAADK------------PAADKPDTDT
Mvan_3789|M.vanbaalenii_PYR-1       SEASEPSSSSQSGDTADAGPSTASQTPT------------TADADPEAEA
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2471c|M.bovis_AF2122/97           SEEP---ESRLMLETQETR---NADVERPHYMPLFVAPQPIPEPLADDED
Rv2444c|M.tuberculosis_H37Rv        SEEP---ESRLMLETQETR---NADVERPHYMPLFVAPQPIPEPLADDED
MMAR_3768|M.marinum_M               PAEPDEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDA
MUL_3715|M.ulcerans_Agy99           PAEP---ESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDA
Mflv_2748|M.gilvum_PYR-GCK          DAET---DADAAEEVADD-----DESQEADEAADERTSRKPSSRIAEDQS
Mvan_3789|M.vanbaalenii_PYR-1       EAEP---DPDPGPDAEPDLADVADEAEEADDIEVAASTDEDPTRQSRTRT
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      ---------------------VGRVGALAVALGVGVAVATGGTAVAWADS
                                                                                      

Mb2471c|M.bovis_AF2122/97           VDDGPDYVADDSDADDEGQLDRPANRRRRRGRRGRGRGRGEQGGSDGDPV
Rv2444c|M.tuberculosis_H37Rv        VDDGPDYVADDSDADDEGQLDRPANRRRRRGRRGRGRGRGEQGGSDGDPV
MMAR_3768|M.marinum_M               DDE-----SGDEGDDDEEQADRPANRRRRRGRRGRGRGRGEQGANDGQDQ
MUL_3715|M.ulcerans_Agy99           DDE-----SGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQ
Mflv_2748|M.gilvum_PYR-GCK          EDTA----SEDTASEDAASEDAASEDAASEDAASDEDVAVASTVAEPAN-
Mvan_3789|M.vanbaalenii_PYR-1       EEAP----SADADDADAADAAAAADGEADADAAEDGEAALATSVADTPDP
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      GSTASSSSSQDSSSKSNPAQTRSSAKSGIGSGAGSGPGSRLDRPASRAPL
                                                                                      

Mb2471c|M.bovis_AF2122/97           DQQSEPRAQQFTSADAAETDDGDDRDSEDTEAGDNGEDENGSLEAGNRRR
Rv2444c|M.tuberculosis_H37Rv        DQQSEPRAQQFTSADAAETDDGDDRDSEDTEAGDNGEDENGSLEAGNRRR
MMAR_3768|M.marinum_M               PGDDGDEAPQKTGGNSTSSDDTEAQDGADSEESDNGDDDNGSADGANRRR
MUL_3715|M.ulcerans_Agy99           PGDDGDEAPQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASRRR
Mflv_2748|M.gilvum_PYR-GCK          ----AAITQNAAITDREVA--RTVRSIVSARPVTAEAIVTDVLTWIGLRP
Mvan_3789|M.vanbaalenii_PYR-1       AAAVAVVSAGPALPDVATAPAAALRTLVSARPVTVQNMVTDVLTWVGLRP
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      GGSGADSSATEQTGAVSSGTSAWRSAGMPAGTSLTGRLADSVRDAVKPWR
                                                                                      

Mb2471c|M.bovis_AF2122/97           RRRRRRKSASGDDNDAALEGPLPDDPPNTVVHERVPRAGDKAGNSQDGG-
Rv2444c|M.tuberculosis_H37Rv        RRRRRRKSASGDDNDAALEGPLPDDPPNTVVHERVPRAGDKAGNSQDGG-
MMAR_3768|M.marinum_M               RRRRRRKSGAGDDGD---EGPAPDDPPNTVVHERAPRSGGKSGNSDSGDD
MUL_3715|M.ulcerans_Agy99           RRRRRRKSGAGDDGD---EGPAPDDPPNTVVHERAPRSGDKSGNSDSGDD
Mflv_2748|M.gilvum_PYR-GCK          SVDDSPAPQTPVSTLVEGLWLAVRQNQYTWNNQRPVADVSIDGPGPDGAV
Mvan_3789|M.vanbaalenii_PYR-1       QADDGPTPPTPVSALVQSLWLAVRQTQYTWNNQRPTADATTSGPGLDGVV
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      --------------------------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      PATTRSTDPTPVETPAEANPEAQPDAHAGSPGE-STAPETQPAPSSRGIR
                                                                                      

Mb2471c|M.bovis_AF2122/97           SGSTEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVER
Rv2444c|M.tuberculosis_H37Rv        SGSTEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVER
MMAR_3768|M.marinum_M               SGGNEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVER
MUL_3715|M.ulcerans_Agy99           SGGNEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVER
Mflv_2748|M.gilvum_PYR-GCK          TGSLNAVDFDDT----ALTYRLTAGPVYGRVRIDADGRFTYTPGAAAAGR
Mvan_3789|M.vanbaalenii_PYR-1       TGNLNAVDYDDS----ALTFTLTGGPAYGRVTIDASGGFTYTPGAAAAGR
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      -------------------------------------------MGVLSDV
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      SMTAVLPDTESTNTESTNTESTVQHDDSERRSSLRSTAASVPELSTPVRL
                                                                                      

Mb2471c|M.bovis_AF2122/97           VMVVRDRVRTEPPLPGTRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLG
Rv2444c|M.tuberculosis_H37Rv        VMVVRDRVRTEPPLPGTRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLG
MMAR_3768|M.marinum_M               VMVVRDRVRTEPPHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLG
MUL_3715|M.ulcerans_Agy99           VMVVRDRVRTEPPHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLG
Mflv_2748|M.gilvum_PYR-GCK          ADTFTIRVDDTSGNPFRVHGLLGLLGITRPTEVTIAIPANPSAPQSVSP-
Mvan_3789|M.vanbaalenii_PYR-1       ADKFTVRIDDTSGNPFHVHGLLGLLGITRPTEVTVVIAASSPVLQSVPSG
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      ADFGKDVIDDRDKWADRFKKVGHFIERNAKGDRLERVAKFGRALGDFSGK
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      ADATAVRALAERLTERRSVTLESVRAFTDVAATTALTSAASVAAATVEPV
                                                                                      

Mb2471c|M.bovis_AF2122/97           IVQNVLPSMEAAFVDIGR-GRNGVLYAGEVNWDAAGLGGADRKIEQALKP
Rv2444c|M.tuberculosis_H37Rv        IVQNVLPSMEAAFVDIGR-GRNGVLYAGEVNWDAAGLGGADRKIEQALKP
MMAR_3768|M.marinum_M               IVQNVLPSMEAAFVDIGR-GRNGVLYAGEVNWDAAGLGGADRKIEQALKP
MUL_3715|M.ulcerans_Agy99           IVQNVLPSMEAAFVDIGR-GRNGVLYAGEVNWDAAGLGGADRKIEQALKP
Mflv_2748|M.gilvum_PYR-GCK          ITVASDSG------TPGR-----VIDGRVTDHIVVNTADAAAVLNALSSA
Mvan_3789|M.vanbaalenii_PYR-1       LTMSELTSRDGVEVTPGRNGAVGVIDGRLTDQLVVNADDAAAVLNSLAFA
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      FTDFFESNLGKRMVKAAR--------------------------------
MAV_3172|M.avium_104                --------------------------------------------------
TH_2316|M.thermoresistible__bu      ALITAAPEATPAVDAEQP--------------------------------
                                                                                      

Mb2471c|M.bovis_AF2122/97           GDYVVVQVSKDPVGHKGARLTTQVSLAGRFLVYVPGASSTGISRKLPDTE
Rv2444c|M.tuberculosis_H37Rv        GDYVVVQVSKDPVGHKGARLTTQVSLAGRFLVYVPGASSTGISRKLPDTE
MMAR_3768|M.marinum_M               GDYIVVQVSKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTE
MUL_3715|M.ulcerans_Agy99           GDYIVVQVSKDPVGHKGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTE
Mflv_2748|M.gilvum_PYR-GCK          LGAPAGFADEAMVIRTTAGTGDSAEHFYRFAETVGGVPVVGSEVILVTNA
Mvan_3789|M.vanbaalenii_PYR-1       LGAVTGFAEPSAITATSVGKGADAEHFYRYTEKIAGVPVLGSEVILVTNA
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      -SPILAAGQHVITGMKLTTGVGDPENGRRFGEGADHMSAAGRTLDSAYPT
MAV_3172|M.avium_104                ---MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAGIVAALLIGDRRWEA
TH_2316|M.thermoresistible__bu      --AAPRLVTGLLAAVGLAPFTANSPLAPTQSTPLLALLGWARRETDRAYT
                                                                                      

Mb2471c|M.bovis_AF2122/97           RQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVARLRERWEQIEAKA
Rv2444c|M.tuberculosis_H37Rv        RQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVARLRERWEQIEAKA
MMAR_3768|M.marinum_M               RQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKA
MUL_3715|M.ulcerans_Agy99           RQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKA
Mflv_2748|M.gilvum_PYR-GCK          DGDVTSVVNYYRGLGDGFDVTPDTSVDDDDELRWIAG------TAYVGSG
Mvan_3789|M.vanbaalenii_PYR-1       AGEVTSVFNYYRGLGEGFGITPDAAVDEDSEVWSIAG------TAYLGPD
MAB_1849|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      SDWDSAASDAYLSQNNGQVTR-----------------------------
MAV_3172|M.avium_104                RGGERGVIYDIALWT-----------------------------------
TH_2316|M.thermoresistible__bu      QQARSLVTARPAVVSTAAVVDP----------------------------
                                                                                      

Mb2471c|M.bovis_AF2122/97           QETKEKAAGAAVALYEEPDVLVKVIRDLFNEDFVGLIVSGDEAWNTINEY
Rv2444c|M.tuberculosis_H37Rv        QETKEKAAGAAVALYEEPDVLVKVIRDLFNEDFVGLIVSGDEAWNTINEY
MMAR_3768|M.marinum_M               VEIKQKAAGAAVALYEEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEY
MUL_3715|M.ulcerans_Agy99           VEIKQKAAGAAVALYEEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEY
Mflv_2748|M.gilvum_PYR-GCK          ADPAAIESFIAASRFSKELLVHSSTDDASPRLAWRVVVHVPDTGEMAPSG
Mvan_3789|M.vanbaalenii_PYR-1       VDPRVLESFLSTTTFTRELVVYT-HDDTTSDLAWRVVVVVPDTGEMSPSG
MAB_1849|M.abscessus_ATCC_1997      -------------------------------MCQRFIIP--------PAV
MSMEG_0055|M.smegmatis_MC2_155      ----------AEALVHADQVVAAVLSREAEQIATTREVLDSEADWLGDMS
MAV_3172|M.avium_104                -------------------VPFGLVGGRLYHLATDWRTYWGPGGAGFGAA
TH_2316|M.thermoresistible__bu      ---------LPADLIGETERIGRITGPGITDGPNRLNIYGTDLGIMWDMG
                                                                                      

Mb2471c|M.bovis_AF2122/97           VNSVAPELVSKLTKYESADGPDGQSAPDVFTVHRIDEQLAKAMDRKVWLP
Rv2444c|M.tuberculosis_H37Rv        VNSVAPELVSKLTKYESADGPDGQSAPDVFTVHRIDEQLAKAMDRKVWLP
MMAR_3768|M.marinum_M               VSSVAPDLVSKLSKYEPAVGSEGQVGPDVFAVHRIDEQLAKAMDRKVWLP
MUL_3715|M.ulcerans_Agy99           VSSVAPDLVSKLSKYEPAVGSEGQVGPDVFAVHRIDEHLAKAMDRKVWLP
Mflv_2748|M.gilvum_PYR-GCK          MTYLIDADGEQAGEVIIAVSNAQAAAATTTAKDWLGATRAITVETRRIWF
Mvan_3789|M.vanbaalenii_PYR-1       ATYVIDADGASAGDVILGTSNAQAATSISIAKDWLGESRVMTIETRTVLW
MAB_1849|M.abscessus_ATCC_1997      LSRLAED-----GDIAEDSRAALSATAACELSWRTLRNAHTRATQASLLT
MSMEG_0055|M.smegmatis_MC2_155      LVTMATGLIPYVGRAAQTAAEIAMVTKAVGASTDQFMMMRDKADENAAEV
MAV_3172|M.avium_104                VRIWDGGLGIWGAVALGAVGAWIGCRRHGIPLPAFADALAPGIILAQAIG
TH_2316|M.thermoresistible__bu      EWRGQRAVHVVFGDTFSGPNMSGDWISNAIMISTSRTLYENPAGFLEQTG
                                                                                      

Mb2471c|M.bovis_AF2122/97           SGGTLVIDRTEAMTVIDVNTGKFTGAGGNLEQTVTKNNLEAAEEIVRQLR
Rv2444c|M.tuberculosis_H37Rv        SGGTLVIDRTEAMTVIDVNTGKFTGAGGNLEQTVTKNNLEAAEEIVRQLR
MMAR_3768|M.marinum_M               SGGTLVIDRTEAMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLR
MUL_3715|M.ulcerans_Agy99           SGGTLVIDRTEAMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLR
Mflv_2748|M.gilvum_PYR-GCK          FTTNEMADSSRMIATYTTSYGFFGLGAPVLPGKVVKKGWFSWDKAAVSAH
Mvan_3789|M.vanbaalenii_PYR-1       FRTYQLIDAPRNITTYRTSYSFFGLGSPSLPGTVVKRGFFGWDAAAVSAH
MAB_1849|M.abscessus_ATCC_1997      SRAAALGAAATGLAKVPETPVFDCRQTTSLPGVAVADPATSKDATAQRAF
MSMEG_0055|M.smegmatis_MC2_155      RDAIGKYEAVAG-DADDTTADDTAGDAPESEPTAAEDSSETSKEDGQSRH
MAV_3172|M.avium_104                RLGNYFNQELYG-RETTLPWGLEIFYRRDPSGYIDPHSLDGVSTGQVALV
TH_2316|M.thermoresistible__bu      PAFQFIPGGQLLSWFFPAEVTVIPTAGVHANGTQYVNYMSVRQWGVPGSW
                                                                              .       

Mb2471c|M.bovis_AF2122/97           LRDIGGIVVIDFIDMVLESNRDLVLRRLTESLARDRTRHQVSEVTSLGLV
Rv2444c|M.tuberculosis_H37Rv        LRDIGGIVVIDFIDMVLESNRDLVLRRLTESLARDRTRHQVSEVTSLGLV
MMAR_3768|M.marinum_M               LRDIGGIVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLV
MUL_3715|M.ulcerans_Agy99           LRDIGGIVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLGLV
Mflv_2748|M.gilvum_PYR-GCK          AN--HAVAYDYFYDVLGRRSYDNAGAPVIVSIKYRPDSYPLGYAN--AMW
Mvan_3789|M.vanbaalenii_PYR-1       AN--MAVVYDYFQDVLGRTSFDDEGALVSVSIRYNPRTSTVGYAN--AFW
MAB_1849|M.abscessus_ATCC_1997      DET--VAVAEFYRNCFGRNSVDNAGMTLVSSIHYG-----VKYSN--AFW
MSMEG_0055|M.smegmatis_MC2_155      EN----PVAAPSGGGGGATSGGGGGAPSSASSAGPAGTPQVPSPPGFGAA
MAV_3172|M.avium_104                VQP--TFLYELLWNLLIFVALLYADRRLTLGHGRLFALYVAGYCVGRFCV
TH_2316|M.thermoresistible__bu      TTNFSAISRYDQATDTWVTVPSSVRSAGWLRSSTPYRAGDQNFQQMAYVL
                                                                                      

Mb2471c|M.bovis_AF2122/97           QLTRKRLGTGLI---EAFSTSCPNCSGRGILLHADPVDSAAATGRKSEPG
Rv2444c|M.tuberculosis_H37Rv        QLTRKRLGTGLI---EAFSTSCPNCSGRGILLHADPVDSAAATGRKSEPG
MMAR_3768|M.marinum_M               QLTRKRLGTGLV---EAFSTSCPHCSGRGILLHADPVDSAPTTGRKADSG
MUL_3715|M.ulcerans_Agy99           QLTRKRLGTGLI---EAFSTSCPHCSGRGILLHADPVDSAPTTGRKADSG
Mflv_2748|M.gilvum_PYR-GCK          DPTIRQFAYGDK---GYFQAALDIVAHEYAHAVVTSMVGNGDPVWESGES
Mvan_3789|M.vanbaalenii_PYR-1       DPSRQLFAFGDA---GYFQASVDVVAHEFTHAVVSYVVGDGGSVLDNGES
MAB_1849|M.abscessus_ATCC_1997      NGSQMAYGDGDGQIFLDFTKSNDVIGHELTHGVTQFTAG----LDYENEA
MSMEG_0055|M.smegmatis_MC2_155      NTPTDAQPGAAA------ASDAAGMLGSVMGAMLGPLGGIVGGVVQAAGQ
MAV_3172|M.avium_104                ELLRDDTATHIAGIRINSFTSTFVFIGAVVYLMAAPKGREDPESLRGNQY
TH_2316|M.thermoresistible__bu      QPVDQVGEDGVRYVYAFGTPSGRQGSVHLSRVPEEHITDVSKYEYWDGNA
                                    :                                                 

Mb2471c|M.bovis_AF2122/97           ARRGKRSKKSRSEESSDRSMVAKVPVHAPGEHPMFKAMAAGLSSLAGRGD
Rv2444c|M.tuberculosis_H37Rv        ARRGKRSKKSRSEESSDRSMVAKVPVHAPGEHPMFKAMAAGLSSLAGRGD
MMAR_3768|M.marinum_M               GRRNRRSKKNRAEEPSEKEAVAKVPTHAPGEHPMFKAMAASSSSEAEHGD
MUL_3715|M.ulcerans_Agy99           GRRNRRSKKNRAEEPSEKEAVAKVPTYAPGEHPMFKAMAASSSSEAEHGD
Mflv_2748|M.gilvum_PYR-GCK          GALNEAYADVFGLLIEGKSGADRWLIAEDSDNGTIRDLANPRSITTSYGP
Mvan_3789|M.vanbaalenii_PYR-1       GALNEAYSDIFGVLVEGKTGDGRWLIGEDSDHGVIRNLADPESIRTAYGP
MAB_1849|M.abscessus_ATCC_1997      GALNESVSDVFGSMFRQWQGQQ---SADKADWLIGKDILGPRALDKGYTC
MSMEG_0055|M.smegmatis_MC2_155      ALQAATQAGAQAAQLAGQAAAAPDVDRADTDEDTDKDPDAEGDKDSDKRD
MAV_3172|M.avium_104                VEEEPAEPEPATVAATTEAATEGVAAPADGAEAAGADATAQRPEESAEPD
TH_2316|M.thermoresistible__bu      WVSSAAHAAPIIGESTRSAGLFGFIIDWANDPNVFGGYLGGLFGAKTGGN
                                                                                      

Mb2471c|M.bovis_AF2122/97           EESGEPAAELAEQAGDQ---------------------PPTDLDDTAQAD
Rv2444c|M.tuberculosis_H37Rv        EESGEPAAELAEQAGDQ---------------------PPTDLDDTAQAD
MMAR_3768|M.marinum_M               GEVEESGEELTAAVDDQTAVQVALDLGQTDETEETDETDETDETDDFDDD
MUL_3715|M.ulcerans_Agy99           GEVEESGEELTAAVDDQTAVQVALDLG---ETEESEETDGTDETDDFDDD
Mflv_2748|M.gilvum_PYR-GCK          HRDRYSTRYTGKGDDGG------------------EHVNSTIFSHAAYLM
Mvan_3789|M.vanbaalenii_PYR-1       YRARVSDMYSGEGDDRG------------------EHVNSTVFSHAAYLM
MAB_1849|M.abscessus_ATCC_1997      LRDMADPAAAHCLSPQP-------------------------SHYRDYVP
MSMEG_0055|M.smegmatis_MC2_155      GEGKEDGTAPRDRESTD-------------------AMGADDDDRNAHPQ
MAV_3172|M.avium_104                VEKPESEETEAEAAEEP----------------------ESEETEAAEEP
TH_2316|M.thermoresistible__bu      VGEMSVQYNEYLGKYVILYG--------------------NGRTNNIEMR
                                                                                      

Mb2471c|M.bovis_AF2122/97           FEDTEDTDEDED-------ELDADEDLEDLDDED------LDEDLDVEDS
Rv2444c|M.tuberculosis_H37Rv        FEDTEDTDEDED-------ELDADEDLEDLDDED------LDEDLDVEDS
MMAR_3768|M.marinum_M               SDDSDDSDEDDDSDETNDTDVDAGEDEDTDDDSDEDSDDDSDEDEDTEDD
MUL_3715|M.ulcerans_Agy99           SDDSDDSDEDDDTDETNDTDVDADEDEDTDDDS--------DEDEDTEDD
Mflv_2748|M.gilvum_PYR-GCK          MTDPATADVSDD--------------------------------------
Mvan_3789|M.vanbaalenii_PYR-1       MTDADTAGVSDE--------------------------------------
MAB_1849|M.abscessus_ATCC_1997      GSDPHEGSGIPN--------------------------------------
MSMEG_0055|M.smegmatis_MC2_155      AGSGTDSAGEDD--------------------------------------
MAV_3172|M.avium_104                GEPEAEEPEEPE--------------------------------------
TH_2316|M.thermoresistible__bu      IADSPEGPWSDP--------------------------------------
                                                                                      

Mb2471c|M.bovis_AF2122/97           ---------------DSDDEDSDEDAADADVDEEDAAG-------LDGSP
Rv2444c|M.tuberculosis_H37Rv        ---------------DSDDEDSDEDAADADVDEEDAAG-------LDGSP
MMAR_3768|M.marinum_M               ELDDDLDEDDLDDDLDEDDDDLDDELDDDDSDSDDEDGES---ELTEPAA
MUL_3715|M.ulcerans_Agy99           ---------------DELDDDLDDELDDDDSDSDDEDSES---ELTEPAA
Mflv_2748|M.gilvum_PYR-GCK          ----------------TWAKVFYHSLERLGATAMFSDGRA---ALLDAAL
Mvan_3789|M.vanbaalenii_PYR-1       ----------------TWAKVFYHSLG-LGTSARFVDGRA---AVLSSAG
MAB_1849|M.abscessus_ATCC_1997      -------------------HAFYLAATKYGSHSWEAVGTVWYQALTSPKA
MSMEG_0055|M.smegmatis_MC2_155      ------------------KKPAMTLPPDLQAASALDTGAG----SAPVHV
MAV_3172|M.avium_104                -----------------AEEPEEPETEEPEADSDEEPEEE------SGEA
TH_2316|M.thermoresistible__bu      ----------------IILATPQQYPGLYAPMIHPWSGTG---YLLDENG
                                                                                      

Mb2471c|M.bovis_AF2122/97           GE-VDVPGVTELAPTRPRRRVAGRPAGPPIRLD------
Rv2444c|M.tuberculosis_H37Rv        GE-VDVPGVTELAPTRPRRRVAGRPAGPPIRLD------
MMAR_3768|M.marinum_M               GR-PAALEVTTIAERPRRRRAAGRPAGPPIHLG------
MUL_3715|M.ulcerans_Agy99           GR-PAALEVTTIAERPRRRRAAGRPAGPPIHLG------
Mflv_2748|M.gilvum_PYR-GCK          SQGLTYAQRLAIAEAFDTVEIYGAAPSQTIAV-------
Mvan_3789|M.vanbaalenii_PYR-1       AQGLTATQLAAIARAFDTVEIYGAAPSSVIAV-------
MAB_1849|M.abscessus_ATCC_1997      TKNMTFKAFAKLTRQIAAGRTGADSPQAAIDEAWTEVGL
MSMEG_0055|M.smegmatis_MC2_155      GADFEHSQLRTVAAATLDHGIPGSAAARGA---------
MAV_3172|M.avium_104                PEQPVAEEPEPAPQQPETKRRWGARLRDRLSGR------
TH_2316|M.thermoresistible__bu      DPDPESLYWNMSMWGPYNVYLMQTDLSSLVEV-------