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MRMTISTLKTEDAGPKTVSRSVQVSAPVATLFDLIADPHRHPEIDGSGTVRDIDVSGPHRLSPGDKFTVG MTQYGVPYKITSKATKVEENRVVEWEHPLGHRWRWELAEVGPGATKVTETFDYSTAKLPIVIELLGMQKK NADGIESTLLALANRYDVH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2610 | - | - | 100% (159) | hypothetical protein Mflv_2610 |
| M. gilvum PYR-GCK | Mflv_3232 | - | 2e-16 | 33.10% (145) | hypothetical protein Mflv_3232 |
| M. gilvum PYR-GCK | Mflv_0146 | - | 5e-12 | 29.63% (135) | hypothetical protein Mflv_0146 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0091 | - | 1e-39 | 50.65% (154) | hypothetical protein Mb0091 |
| M. tuberculosis H37Rv | Rv0088 | - | 1e-39 | 50.65% (154) | hypothetical protein Rv0088 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4338c | - | 3e-38 | 50.00% (148) | hypothetical protein MAB_4338c |
| M. marinum M | MMAR_0234 | - | 7e-41 | 51.88% (160) | hypothetical protein MMAR_0234 |
| M. avium 104 | MAV_5243 | - | 2e-40 | 51.95% (154) | hypothetical protein MAV_5243 |
| M. smegmatis MC2 155 | MSMEG_0859 | - | 3e-14 | 37.39% (115) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4053 | - | 4e-09 | 31.50% (127) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4879 | - | 1e-38 | 51.61% (155) | hypothetical protein MUL_4879 |
| M. vanbaalenii PYR-1 | Mvan_0758 | - | 7e-12 | 34.19% (117) | hypothetical protein Mvan_0758 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0091|M.bovis_AF2122/97 --------------------------------------------------
Rv0088|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0234|M.marinum_M --------------------------------------------------
MUL_4879|M.ulcerans_Agy99 --------------------------------------------------
MAV_5243|M.avium_104 --------------------------------------------------
MAB_4338c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2610|M.gilvum_PYR-GCK --------------------------------------------------
TH_4053|M.thermoresistible__bu --------------------------------------------------
Mvan_0758|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 MAPPRKHETDAILDAARALVLTEGPRAAGVAAIAKASGAPVGTLYHRFGN
Mb0091|M.bovis_AF2122/97 --------------------------------------------------
Rv0088|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0234|M.marinum_M --------------------------------------------------
MUL_4879|M.ulcerans_Agy99 --------------------------------------------------
MAV_5243|M.avium_104 --------------------------------------------------
MAB_4338c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2610|M.gilvum_PYR-GCK --------------------------------------------------
TH_4053|M.thermoresistible__bu --------------------------------------------------
Mvan_0758|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 RDGILKATWLRGIERFQRRAMAADGATPVDVAVAMAGAVLQFARDEPEDA
Mb0091|M.bovis_AF2122/97 -------------------MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWR
Rv0088|M.tuberculosis_H37Rv -------------------MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWR
MMAR_0234|M.marinum_M --------------------------------------------------
MUL_4879|M.ulcerans_Agy99 --------------------------------------------------
MAV_5243|M.avium_104 --------------------------------------------------
MAB_4338c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2610|M.gilvum_PYR-GCK --------------------------------------------------
TH_4053|M.thermoresistible__bu --------------------------------------------------
Mvan_0758|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 RLLLSIRRADLLDGGPDADFDATLADMNAPVFERLHELARGIFGRDDDRA
Mb0091|M.bovis_AF2122/97 RVRTGDLGLAVWGGREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVSRS
Rv0088|M.tuberculosis_H37Rv RVRTGDLGLAVWGGREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVSRS
MMAR_0234|M.marinum_M ----------------------------MTRGELMTVVVVDAGPRRVSRS
MUL_4879|M.ulcerans_Agy99 ----------------------------------MTVVVVDAGPRRVSRS
MAV_5243|M.avium_104 ----------------------------------MTVTVVDRGPRQVSRR
MAB_4338c|M.abscessus_ATCC_199 ----------------------------------MSVSVVDPGPQQISRS
Mflv_2610|M.gilvum_PYR-GCK -----------------------------MRMTISTLKTEDAGPKTVSRS
TH_4053|M.thermoresistible__bu -------------------------------MS-----DIQTTGTSLAVH
Mvan_0758|M.vanbaalenii_PYR-1 -------------------------------MSPACDRGLTRMTETLIVD
MSMEG_0859|M.smegmatis_MC2_155 MDAVMRAVADLPYATVRRHIDDGKWPVWLSEDLATSVRRLLSVDKIVSAS
:
Mb0091|M.bovis_AF2122/97 VEVAAPAAELFAIVADPRRHRELDGSGTVRG-NIKVPAKLVVGSKFSTKM
Rv0088|M.tuberculosis_H37Rv VEVAAPAAELFAIVADPRRHRELDGSGTVRG-NIKVPAKLVVGSKFSTKM
MMAR_0234|M.marinum_M VEVAAPAAELFAIVADPRRHSELDGSGTVRD-NIKAPVTLVAGTKFSTNM
MUL_4879|M.ulcerans_Agy99 VEVAALAAELFAIVADPRCHSELDGSGTVRD-NIKAPVTLVAGTKFSTNM
MAV_5243|M.avium_104 VDVAAPAAQLYALVADPRRHHELDGSGTVRD-NISVPAKLVEGSKFSTHM
MAB_4338c|M.abscessus_ATCC_199 VEVSAPATELFAIAADPRRHHELDGSGTVGQ-NIRTPDHLQVGSRFSTGM
Mflv_2610|M.gilvum_PYR-GCK VQVSAPVATLFDLIADPHRHPEIDGSGTVRDIDVSGPHRLSPGDKFTVGM
TH_4053|M.thermoresistible__bu TTVNAPARTVFDVLADPTTHARIDGTGWVRE-PVDGARLTGAGQIFRMGM
Mvan_0758|M.vanbaalenii_PYR-1 TIVDAPASTVFAVLADPATHAAIDGTGWVRE-SLDGEPITRSGQMFRMAM
MSMEG_0859|M.smegmatis_MC2_155 REIAAPSDVIFELIADPAQQPRWDGNENLLR-MASGGRVRGVGEVFTMEI
: * :: : *** : **. : * * :
Mb0091|M.bovis_AF2122/97 KLFG-----LPYRITSRVTALKPNELVEWSHP------------------
Rv0088|M.tuberculosis_H37Rv KLFG-----LPYRITSRVTALKPNELVEWSHP------------------
MMAR_0234|M.marinum_M RMFG-----VPYRITSTVTALKPNELVEWRHP------------------
MUL_4879|M.ulcerans_Agy99 RMFG-----VPYRITSTVTALKPNELVEWRHP------------------
MAV_5243|M.avium_104 RMFG-----LPYRITSTITELKPNEVVEWRHP------------------
MAB_4338c|M.abscessus_ATCC_199 RMFG-----LPYRITSTVTELDPDKVVEWRHP------------------
Mflv_2610|M.gilvum_PYR-GCK TQYG-----VPYKITSKATKVEENRVVEWEHP------------------
TH_4053|M.thermoresistible__bu YHEN--HPHRHYEIANRVEVFDPPHAIAWQPGAEPRHIPGRGADATGPVE
Mvan_0758|M.vanbaalenii_PYR-1 YFANPAFADGHYEVANKVIAFEPDRAIGWEPG---------QAREDGTVE
MSMEG_0859|M.smegmatis_MC2_155 KQGG--------FRDNHVIEFEEGRRIAWRPAVAG-------------EQ
. . .. . : *
Mb0091|M.bovis_AF2122/97 -LGHRWRWEFESLS----PTLTRVTETFDYHAAGAIKNGLKFYEMTGFAK
Rv0088|M.tuberculosis_H37Rv -LGHRWRWEFESLS----PTLTRVTETFDYHAAGAIKNGLKFYEMTGFAK
MMAR_0234|M.marinum_M -AGHRWRWEFESLS----PTLTRVTETFDYHAAGELKNKLKYYERIGACK
MUL_4879|M.ulcerans_Agy99 -AGHRWRWEFESLS----PTLTRVTETFDYHAAGELKNKLKYYERIGACK
MAV_5243|M.avium_104 -LGHRWRWEFESLS----PTRTRVTETFDYRDAGALKNRLKYYERMGFAK
MAB_4338c|M.abscessus_ATCC_199 -LGHRWRWEFVALS----PTSTRVTETFDFRNAGPIQSLLN-YKLPGFVK
Mflv_2610|M.gilvum_PYR-GCK -LGHRWRWELAEVG----PGATKVTETFDYSTA----KLPIVIELLGMQK
TH_4053|M.thermoresistible__bu FGGWIWRYDLAPQHAPGAPAGTRVTLTYDWSQVP--AADRRAMRFPPFPP
Mvan_0758|M.vanbaalenii_PYR-1 HGGWTWRYDLEAVG----PGLTRVTLTYDWSAVP--ATLREHIAFPPFPV
MSMEG_0859|M.smegmatis_MC2_155 PLGHLWRWELQPAG----EGRTLVTHTYDWTQLT---DEKRFPKASATTA
* **::: * ** *:*:
Mb0091|M.bovis_AF2122/97 SNAAGIEATLAKLSDQYARGRA
Rv0088|M.tuberculosis_H37Rv SNAAGIEATLAKLSDQYARGRA
MMAR_0234|M.marinum_M ANAAGIEATLAKLRDRYAAR--
MUL_4879|M.ulcerans_Agy99 ANAAGIEATLAKLRDRYAAR--
MAV_5243|M.avium_104 ANASGIEATLAKLRDRYPG---
MAB_4338c|M.abscessus_ATCC_199 ANAKGIEATLRRLQARYS----
Mflv_2610|M.gilvum_PYR-GCK KNADGIESTLLALANRYDVH--
TH_4053|M.thermoresistible__bu EHLVNSLRHLKELAERDVPR--
Mvan_0758|M.vanbaalenii_PYR-1 DHLHNSLANLAKLAAG------
MSMEG_0859|M.smegmatis_MC2_155 DKLQESVDRLAAIVEG------
: * :