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GTVIERIDLARGGWRSRHSALHLAVAAARTCLQQARRDADDVDLLINAGIYRDRNLAEPALAALIQQDVG ANPENPHSEGHGTFSFDVANGACGVLTALQIVDGFLRSRTIACALVVASDADPGRRHRESFPFAPAGAAL LCKWTDDVGGLGPVSWLNTTDGGETFCATVGLEDSRNVLRFQVSAGLDEHFATAGAEAAGRCLEASGVAL SAVDVIVAAPARAGFRAALAAKLGTAAERITVADDERMHTAALPTALHRVSDEIPPGGRILLVAVGAGIT AGAALYRKPLPAT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2539 | - | - | 100% (294) | 3-oxoacyl-(ACP) synthase III |
| M. gilvum PYR-GCK | Mflv_2540 | - | 2e-13 | 25.51% (294) | Beta-ketoacyl-acyl-carrier-protein synthase I |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0547c | fabH | 2e-06 | 24.07% (295) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. tuberculosis H37Rv | Rv0533c | fabH | 2e-06 | 24.07% (295) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1141c | - | 2e-08 | 24.07% (295) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. marinum M | MMAR_3473 | - | 1e-107 | 66.44% (292) | ketoacyl-acyl carrier protein synthase III |
| M. avium 104 | MAV_4612 | - | 2e-07 | 23.79% (290) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. smegmatis MC2 155 | MSMEG_3951 | - | 4e-90 | 60.81% (296) | hypothetical protein MSMEG_3951 |
| M. thermoresistible (build 8) | TH_1180 | - | 7e-99 | 65.07% (292) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0632 | fabH | 2e-07 | 22.22% (288) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0547c|M.bovis_AF2122/97 MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDEWIYTRTGIK
Rv0533c|M.tuberculosis_H37Rv MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDEWIYTRTGIK
MUL_0632|M.ulcerans_Agy99 MTEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSSDEWIYSRTGIK
MAV_4612|M.avium_104 MKQISATSGPTNIGLLSVGSYRPQRAVTNDELCQNIDSSDEWIYSRTGIK
MAB_1141c|M.abscessus_ATCC_199 MTDIAEITGINKIGLLSLGAYRPERVVTNDEICERIESSDEWIYTRTGIK
MMAR_3473|M.marinum_M ----------------------------MGTVIDRVDVAHSGWRNRHSAL
MSMEG_3951|M.smegmatis_MC2_155 ----------------------------MGTIIERVEISEAGWRNRHSAL
Mflv_2539|M.gilvum_PYR-GCK ----------------------------MGTVIERIDLARGGWRSRHSAL
TH_1180|M.thermoresistible__bu ----------------------------MGTVVERVHVTHARLRGRRSAL
. : :.:. : * .
Mb0547c|M.bovis_AF2122/97 TRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPA
Rv0533c|M.tuberculosis_H37Rv TRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPA
MUL_0632|M.ulcerans_Agy99 TRRFAAPEESAASMAIEASREAIAKAALTGSDIDGVIVATSTHFLQTPAC
MAV_4612|M.avium_104 TRRFAARDESTASMATEAGREAIAKAGLEASDIDCVVVATSTHFLQTPAC
MAB_1141c|M.abscessus_ATCC_199 TRRFAADEETAQTLAIEAGRKAIANALLTGAEIDAVIVATSTHYLQTPAS
MMAR_3473|M.marinum_M HLAVAAAKDCLQGAGCDPDELDLVVNAGIYRDRN-LGEPALAALIQDDIG
MSMEG_3951|M.smegmatis_MC2_155 RLAVAAAKRCLHRAGCDPDSIDLLINAGIYRDRN-LGEPALAALIQEMIG
Mflv_2539|M.gilvum_PYR-GCK HLAVAAARTCLQQARRDADDVDLLINAGIYRDRN-LAEPALAALIQQDVG
TH_1180|M.thermoresistible__bu QLAVAASRACLRAAHRSARDVDLLVNAGIYRDRN-LGEPALAALIQEDIG
.** .. : : : : .: : :*
Mb0547c|M.bovis_AF2122/97 APMVAASLGAKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTE
Rv0533c|M.tuberculosis_H37Rv APMVAASLGAKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTE
MUL_0632|M.ulcerans_Agy99 APIVAAALGCQNVPAFDISAGCSGFGHALGIAADMIRGGSAATILVIGTE
MAV_4612|M.avium_104 GPAVAAALGATGVPAFDISAGCAGFGYALGVAADMVRGGTAGKVLVLGSE
MAB_1141c|M.abscessus_ATCC_199 APAVATALGAQGVPAFDLSAGCAGFGYAVGVAGDMIRGGSASKVLVIGSE
MMAR_3473|M.marinum_M ANPEDPHAGAHGTFSFDIANGACGVLTALQIVDGFLRTHSISRALIVAS-
MSMEG_3951|M.smegmatis_MC2_155 ANLHDPHTGEHGTFSFDVANGECGVLTALQIVDGFLRAGIIKAALIVAS-
Mflv_2539|M.gilvum_PYR-GCK ANPENPHSEGHGTFSFDVANGACGVLTALQIVDGFLRSRTIACALVVAS-
TH_1180|M.thermoresistible__bu ANPEHPHAGGHGTFSFDVANGTCGVLTALQIVDGYLTSRTVDCALVVAG-
. . . .**:: * .*. *: . . : *::.
Mb0547c|M.bovis_AF2122/97 KLSPTIDMYDRGNCFIFADGAAAVVVGETP-FQGIGPTVAGSDGEQADAI
Rv0533c|M.tuberculosis_H37Rv KLSPTIDMYDRGNCFIFADGAAAVVVGETP-FQGIGPTVAGSDGEQADAI
MUL_0632|M.ulcerans_Agy99 KLSPTVDMTDRSNCFIFVDGAASVLVGHSP-IQGIGPTVWGSDGEQAAAI
MAV_4612|M.avium_104 KLSPTVDMTDRSNCFIFADGAAGVVVGETP-TQGIGPTVWGSDGTQATAI
MAB_1141c|M.abscessus_ATCC_199 KLSPALDMTDRGNCFIFGDGAGAVVVGETA-EQGIGPTVWGSDGSQSNAI
MMAR_3473|M.marinum_M DADPGHGMSEH---FPFSATGAALLCGWSDDTYGLSRVQWANAVNGK---
MSMEG_3951|M.smegmatis_MC2_155 DANPGFGMSKH---FPYSPVGSALLCRWNDGDDGLGPVRWSARTDG----
Mflv_2539|M.gilvum_PYR-GCK DADPGRRHRES---FPFAPAGAALLCKWTDDVGGLGPVSWLNTTDG----
TH_1180|M.thermoresistible__bu DADPGRGLSED---FPFAPVGAALLCGWTDDEYGLGPVHWACRPDD----
. .* . * : ...:: . *:. .
Mb0547c|M.bovis_AF2122/97 RQDIDWITFAQNP--SGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAG-
Rv0533c|M.tuberculosis_H37Rv RQDIDWITFAQNP--SGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAG-
MUL_0632|M.ulcerans_Agy99 RQDIDWISHAENP--AGPRPFLRMEGTAVFRWAAFEMGKVGQQAMDAAG-
MAV_4612|M.avium_104 RQDIDWMDYLDRP--TGPRPFLRLEGSAVFRWAAFEMGKVGQQAMDAAG-
MAB_1141c|M.abscessus_ATCC_199 RQDIDWMDFAAAPDPEGPRPYLRIEGTSVFRWAAFEMGKVGQRAMEAAK-
MMAR_3473|M.marinum_M ----ADESFSATVGFADARNVLRFAESAEADEEFAAVAAHAVRECLAAN-
MSMEG_3951|M.smegmatis_MC2_155 ------EGFCARVGFRDGRNVLRFQESAAFDVDLAGVCALAASSCLAES-
Mflv_2539|M.gilvum_PYR-GCK -----GETFCATVGLEDSRNVLRFQVSAGLDEHFATAGAEAAGRCLEAS-
TH_1180|M.thermoresistible__bu -----GRNFRATVSQVDRRNLLRFGWSDHLDEVYAATAAEAVARCLAAEG
. . * :*: . .
Mb0547c|M.bovis_AF2122/97 --VRPDQIDVFVPHQANSRINELLVKNLQLRPDAVVANDIEHTGNTSAAS
Rv0533c|M.tuberculosis_H37Rv --VRPDQIDVFVPHQANSRINELLVKNLQLRPDAVVANDIEHTGNTSAAS
MUL_0632|M.ulcerans_Agy99 --VKPDEIDVFIPHQANSRINELLTKNLQLRPDAVIANDIEHTGNTSAAS
MAV_4612|M.avium_104 --VRPDEIDVFLPHQANSRINEILAKSLELRPDAVIANDIEHTGNTSAAS
MAB_1141c|M.abscessus_ATCC_199 --VGPEQIDVFVPHQANTRINELLAKNLHLRADAVIANDIEHTGNTSAAS
MMAR_3473|M.marinum_M -CVALSSVDMIVAAPPRPGFRAALSARLGVAAELIGVADDRRMHTAALPA
MSMEG_3951|M.smegmatis_MC2_155 -SLTLSDV-AICVAPARQRFRAALAAKLGVPPAHLVVAADPRTHTAALPA
Mflv_2539|M.gilvum_PYR-GCK -GVALSAVDVIVAAPARAGFRAALAAKLGTAAERITVADDERMHTAALPT
TH_1180|M.thermoresistible__bu PGSDSSDVDVIVAAPARARFRAALAELLRVPVERIAVAPGESIHTAALAA
. : : .. :. * * : . .:: .:
Mb0547c|M.bovis_AF2122/97 IPLAMAELLTTGAAKPGDLALLIGYGAGLSYAAQVVRMPKG---------
Rv0533c|M.tuberculosis_H37Rv IPLAMAELLTTGAAKPGDLALLIGYGAGLSYAAQVVRMPKG---------
MUL_0632|M.ulcerans_Agy99 IPLAMAELLATGAAKPGDLALLIGYGAGLSYAAQVVRMPNS---------
MAV_4612|M.avium_104 IPLAMAEVLATGAAKAGDLALLIGYGAGLSYAAQVVRLPPG---------
MAB_1141c|M.abscessus_ATCC_199 VPLAMETLLSTGAAKPGDLALLIGYGAGLSYAAQVVRMPPVPFE------
MMAR_3473|M.marinum_M AFEQQIAR----VPVGAQ-ILFVAAGAGVTAGAALYRRPPGRAA------
MSMEG_3951|M.smegmatis_MC2_155 ALRRRDSGGGDSGPVDTRPVLLVAGAAGPVAGAALYRSPVAVRADGSQHS
Mflv_2539|M.gilvum_PYR-GCK ALHRVSDE----IPPGGR-ILLVAVGAGITAGAALYRKPLPAT-------
TH_1180|M.thermoresistible__bu ALPQ--------IPVGSR-ALIVAAGAGVTAGAAMYHRPDCRGR------
. *::. .** .* : : *
Mb0547c|M.bovis_AF2122/97 ---------
Rv0533c|M.tuberculosis_H37Rv ---------
MUL_0632|M.ulcerans_Agy99 ---------
MAV_4612|M.avium_104 ---------
MAB_1141c|M.abscessus_ATCC_199 ---------
MMAR_3473|M.marinum_M ---------
MSMEG_3951|M.smegmatis_MC2_155 AIDFQDLGQ
Mflv_2539|M.gilvum_PYR-GCK ---------
TH_1180|M.thermoresistible__bu ---------