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DEDEIGGTAAEMRALADEAEAEAAEAEAVAAAAGARARALQLRRRAERAEAAAEVDAACEATHEGAADGQ ATASRNGAEEPTGNSADVLESDDVAETEELRADDDEPVAAGSAKADESEADELADESERSRRGLLRRPKL STLTAALAVLVILAALAGSAYMVLQHRDATRQRERVAEFAAAARQGVITLTSLDFQDAKQGIGRILDNST GSFKDELLKSSDDFIQVVQQAQVVEQGTVQAVAVDRNSMTDDSAVVLVASTSEVTNAAGAKKDPRKYRLI VTITRDGDQLKMSKVEFVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0306 | - | - | 100% (300) | hypothetical protein MUL_0306 |
| M. ulcerans Agy99 | MUL_3858 | - | 7e-45 | 37.84% (296) | hypothetical protein MUL_3858 |
| M. ulcerans Agy99 | MUL_3924 | - | 1e-26 | 33.33% (222) | Mce associated membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1398c | - | 2e-53 | 43.58% (296) | hypothetical protein Mb1398c |
| M. gilvum PYR-GCK | Mflv_2526 | - | 2e-55 | 46.39% (291) | hypothetical protein Mflv_2526 |
| M. tuberculosis H37Rv | Rv1363c | - | 6e-54 | 43.92% (296) | hypothetical protein Rv1363c |
| M. leprae Br4923 | MLBr_02597 | - | 5e-09 | 30.32% (155) | hypothetical protein MLBr_02597 |
| M. abscessus ATCC 19977 | MAB_4593c | - | 3e-10 | 26.29% (251) | hypothetical protein MAB_4593c |
| M. marinum M | MMAR_4687 | - | 1e-156 | 97.33% (300) | hypothetical protein MMAR_4687 |
| M. avium 104 | MAV_0938 | - | 3e-59 | 46.62% (296) | hypothetical protein MAV_0938 |
| M. smegmatis MC2 155 | MSMEG_4771 | - | 7e-57 | 44.44% (306) | hypothetical protein MSMEG_4771 |
| M. thermoresistible (build 8) | TH_0392 | - | 1e-40 | 50.31% (163) | POSSIBLE MEMBRANE PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_4132 | - | 1e-56 | 44.85% (301) | hypothetical protein Mvan_4132 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0306|M.ulcerans_Agy99 ---------------------------MDEDEIG--------GTAAEMRA
MMAR_4687|M.marinum_M MHAALLSGGCGVSTGIGNGAADSRSAPVDEDEIG--------GTAAEMRA
Mflv_2526|M.gilvum_PYR-GCK ------------MPSFRRRDSVIEADRVEESTVD----PEGVPAGDRARA
Mvan_4132|M.vanbaalenii_PYR-1 ------------MPSFRRRDAVIDADRVEESTVE----PESVTEADQARA
TH_0392|M.thermoresistible__bu --------------------------------------------------
MSMEG_4771|M.smegmatis_MC2_155 ------------MPSRKPTLPVINGSHGDDQDADRSDSPAGELSADDALL
Mb1398c|M.bovis_AF2122/97 ------------------------MAETTEPPSD------AGTSQADAMA
Rv1363c|M.tuberculosis_H37Rv ------------------------MAETTEPPSD------AGTSQADAMA
MAV_0938|M.avium_104 ------------------------MADAKKPPHD------SATSDEDVKA
MAB_4593c|M.abscessus_ATCC_199 ----------------------MADDAADKDAKN--------ADESAVTS
MLBr_02597|M.leprae_Br4923 --------------------------------------------------
MUL_0306|M.ulcerans_Agy99 LADEAEAEAAEAEAVAAAAGARARALQLRRRAERAEAAAEVDAACEATHE
MMAR_4687|M.marinum_M LAEEAEAEAAEAEALAAAAGARARALQLRRRAERAEAAAEVDAACEATHE
Mflv_2526|M.gilvum_PYR-GCK LADVAEAEAAEAEAMAAAARARARAAKLRQEALAAAADSDGETARTDAVA
Mvan_4132|M.vanbaalenii_PYR-1 LAEEAEAEAAEAEAMAAAAKARARAARLRRQALAADVAAKPEVGEDSATV
TH_0392|M.thermoresistible__bu -------------------------VHWRPXXXAAPDSS-----------
MSMEG_4771|M.smegmatis_MC2_155 LAEQAEAEAAEAEAIAAAARARAEALRLRRQAEEAAKRSSEADAENESVD
Mb1398c|M.bovis_AF2122/97 L--AAEAEAAEAEALAAAARARARAARLKREALAMAP-------------
Rv1363c|M.tuberculosis_H37Rv L--AAEAEAAEAEALAAAARARARAARLKREALAMAP-------------
MAV_0938|M.avium_104 LLEEAEAEAAEAEALAAAARARARAARLRREAQAQAAKAAAETSEADEHA
MAB_4593c|M.abscessus_ATCC_199 DAEKAESSAPSSAAVESTAEGTTEAATAEVADFDAED-------------
MLBr_02597|M.leprae_Br4923 MSPRRKFQAGEGLLLVSHTVASQRRWGLP---------------------
MUL_0306|M.ulcerans_Agy99 GAADGQATASRNGAEEPTGNSADVLESDDVAETEELRADDDEPVAAGSAK
MMAR_4687|M.marinum_M GAADGQATASHNGAEEPSANSADVLESDDVAETEELSADDDEPAAAGSAE
Mflv_2526|M.gilvum_PYR-GCK STTEATDDAD----------DAELLDID-DDRDDDLDGDETDAVGEAES-
Mvan_4132|M.vanbaalenii_PYR-1 GDADVDGDDDAVTGS--ADAEPEVVDIETAETDETAETDDSAPADGGAA-
TH_0392|M.thermoresistible__bu --------------------------------------DTTPAAG-----
MSMEG_4771|M.smegmatis_MC2_155 ESETGEPEDAENAED--TEDTEAAEDTEAAEKDSAGKPEAQEAQELPEA-
Mb1398c|M.bovis_AF2122/97 AEDE--NVPEEYA------DWEDAEDYDDYDDYEAADQEAARSAS-----
Rv1363c|M.tuberculosis_H37Rv AEDE--NVPEEYA------DWEDAEDYDDYDDYEAADQEAARSAS-----
MAV_0938|M.avium_104 ADDEPAETDDEVS------DSVEATDADDTETTQAQTKEAAKEAEPNEEA
MAB_4593c|M.abscessus_ATCC_199 --------------------SEKTKDSGAVEDSDDEDISLEPDEE-----
MLBr_02597|M.leprae_Br4923 --------------------------------------------------
MUL_0306|M.ulcerans_Agy99 ADESEADELADESERSRRGLLRRPKLS----TLTAALAVLVILAALAGSA
MMAR_4687|M.marinum_M ADESEADELADESERSRRGLLRRPKLS----TLTAALAVLVILAALAGSA
Mflv_2526|M.gilvum_PYR-GCK --------------PTRKRLLRRPGWASVGVALVLVIAVLGTAALLAVSG
Mvan_4132|M.vanbaalenii_PYR-1 --------------PSRRRRIPRPGWK----AAVATVVALATVALLGASG
TH_0392|M.thermoresistible__bu ---------------ARRRFRLR--WG----IVARAAAIVAICLLLAASG
MSMEG_4771|M.smegmatis_MC2_155 --------------KLTTR-TNAPVWK----WIAAGVTVVIILGLLTVSG
Mb1398c|M.bovis_AF2122/97 --------------WRRRLRVRLPRLS----TIAMAAAVVIICGFTGLSG
Rv1363c|M.tuberculosis_H37Rv --------------WRRRLRVRLPRLS----TIAMAAAVVIICGFTGLSG
MAV_0938|M.avium_104 AEET-AEDAESESKARSRRRLRLPSWS----VAWKAAVIALICAFVAASG
MAB_4593c|M.abscessus_ATCC_199 ---------------ENPKRIRGRHWA-------LTAAAIVAIAIVALAA
MLBr_02597|M.leprae_Br4923 --------------------------------LAATFAALVMVAAITAST
. :
MUL_0306|M.ulcerans_Agy99 YMVLQHRDATRQRERVAEFAAAARQGVITLTSLDFQDAKQGIGRILDNST
MMAR_4687|M.marinum_M YMVLQHRDATRQRERVAEFAAAARQGVITLTSLDFQDAKQGIGRILDNST
Mflv_2526|M.gilvum_PYR-GCK YMRLEHRDAENLRQQNAEYAAAARQSVVTLMSLDFNKAEEDVQRIIDNST
Mvan_4132|M.vanbaalenii_PYR-1 YMVWTHRGAEKLRQQNAEYAAAARQSVVTLMSLDFNKAEEDVQRIIDNST
TH_0392|M.thermoresistible__bu YMVWYHQQVEAEKQRAAEFAAAARQGIVSLMSLDFNRAEEDVQRIIDNST
MSMEG_4771|M.smegmatis_MC2_155 LMMYHHKQMQDDQRRAAEFAAAARQGVVTLMSLDHTHAKEDVQRIIDMST
Mb1398c|M.bovis_AF2122/97 YIVWQHHEATERQQRAAAFAAGAKQGVINMNSLDFNKAKEDVARVIDSST
Rv1363c|M.tuberculosis_H37Rv YIVWQHHEATERQQRAAAFAAGAKQGVINMTSLDFNKAKEDVARVIDSST
MAV_0938|M.avium_104 YMMWERHQTSERNQRIANFLAAARQGVVNMTSLDFNKAKEDVQRVIDSST
MAB_4593c|M.abscessus_ATCC_199 IIGRLYEEQRIEEQSSREALAAAQEFANVMINVDSAKLDESSNKTLERST
MLBr_02597|M.leprae_Br4923 LMSISHASRELAVAKDQQVLSYVKWFMTQFTTLDPYHANDYVARILAQAT
: : .: : .:* .: : : :*
MUL_0306|M.ulcerans_Agy99 GSFKDELLKSSDDFIQVVQQAQVVEQGTVQAVAVDRNSMTDDSAVVLVAS
MMAR_4687|M.marinum_M GSFKDELLKSSDDFIQVVQQAQVVEQGTVQAVAVDRNSMTDDSAVVLVAS
Mflv_2526|M.gilvum_PYR-GCK GQFKDDFESQAAEFVKVAQDSKVVTEVTVNSTAVER--MTGDGAEVLVAA
Mvan_4132|M.vanbaalenii_PYR-1 GQFKTDFESQAADFVKVAQDSKVVTEVSVNSTAVES--MSDDSAEVLVAA
TH_0392|M.thermoresistible__bu GEFREEFESAAEDFATVAKESKVITDVSVNATAVQS--MTEDSAEVLVAA
MSMEG_4771|M.smegmatis_MC2_155 GDFRADFEATAEDFAKVAEQAKVTTEAQVNATAVDS--MTDDSAVVLVAA
Mb1398c|M.bovis_AF2122/97 GEFRDDFQQRAADFTKVVEQSKVVTEGTVNATAVES--MNEHSAVVLVAA
Rv1363c|M.tuberculosis_H37Rv GEFRDDFQQRAADFTKVVEQSKVVTEGTVNATAVES--MNEHSAVVLVAA
MAV_0938|M.avium_104 GQFRDDFQQRAKDFTTVVEQSKVVTQGTVNAAAVQS--IDGNSALVLVAA
MAB_4593c|M.abscessus_ATCC_199 GDFKQKYSESSTTLRQVMIENKAKATGVVVDSAVKS--AAPDKVEVLLFI
MLBr_02597|M.leprae_Br4923 GDFAKQYNEKVNEILLQVAQAEPATG-TVLDAGVER-WNDDGSANVLVAT
*.* . : : : * .*. . **:
MUL_0306|M.ulcerans_Agy99 TSEVTNAAGAKKDPRKYRLIVTITRDGDQLKMSKVEFVP
MMAR_4687|M.marinum_M TSEVTNAAGAKKDPRKYRLIVTITRDGDQLKMSKVEFVP
Mflv_2526|M.gilvum_PYR-GCK SSRVTNTAGADQEPRTWRLSVSLVREDGQIKMSKVEFVP
Mvan_4132|M.vanbaalenii_PYR-1 SSRVTNTAGANQEPRTWRLSVSLKREDGQIKMAKVEFVP
TH_0392|M.thermoresistible__bu TSSITNEAGANQDPRSWRLFVSVTRDDGQLKMSKVEFVP
MSMEG_4771|M.smegmatis_MC2_155 TSRISNSAGADQDPRNWRLSVTVKQDGDQIKLAKVEFVP
Mb1398c|M.bovis_AF2122/97 TSRVTNSAGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP
Rv1363c|M.tuberculosis_H37Rv TSRVTNSAGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP
MAV_0938|M.avium_104 TSRITNAAGAKDEPRNWRLKVTVTDEGGQYKMSKLEFVP
MAB_4593c|M.abscessus_ATCC_199 DQAVSNVAIPDARMDRSRVQITMQKVDGRWLASDVELT-
MLBr_02597|M.leprae_Br4923 EVTSKSPDEKQVLENTNRWTATATREGNQWKISNLLQVI
.. . * : ..: :.: .