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SVTNSSSGVRSSSRAPFYRAVGDEVEVFRAAARRGLPVLLKGPTGCGKTRFVEAVAHELGRDLITVAGHE DMTSADLVGRFLLKGGETVWVDGPLTRAVRTGALCYLDEIVEARQDTTVVIHPLADHRRELPVDRLGVTV PAAPGFQLVISYNPGYQSVLKNIKESTRQRFIAIELDFPPPDAETEIVAHEAGIDPDTARVLVRIGNAIR NIDGSPLREVSSTRMLILAGGLVAEGLGLRRAVQAAIVETLSDDGDVIRALGELVDALLPAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2458 | - | - | 100% (273) | ATPase |
| M. gilvum PYR-GCK | Mflv_4155 | - | 2e-97 | 65.28% (265) | ATPase |
| M. gilvum PYR-GCK | Mflv_1772 | - | 6e-66 | 49.21% (254) | ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2450c | - | 4e-09 | 26.34% (262) | hypothetical protein Mb2450c |
| M. tuberculosis H37Rv | Rv2426c | - | 4e-09 | 26.34% (262) | hypothetical protein Rv2426c |
| M. leprae Br4923 | MLBr_01810 | moxR | 5e-08 | 26.32% (190) | MoxR homolog |
| M. abscessus ATCC 19977 | MAB_1619 | - | 9e-10 | 25.19% (262) | hypothetical protein MAB_1619 |
| M. marinum M | MMAR_3752 | - | 1e-09 | 25.19% (262) | hypothetical protein MMAR_3752 |
| M. avium 104 | MAV_1270 | - | 6e-99 | 67.70% (257) | putative denitrification regulatory protein nirQ |
| M. smegmatis MC2 155 | MSMEG_6809 | cbbQ | 1e-128 | 85.71% (266) | CbbQ protein |
| M. thermoresistible (build 8) | TH_4050 | - | 1e-67 | 50.59% (255) | PUTATIVE ATPase associated with various cellular activities, |
| M. ulcerans Agy99 | MUL_3695 | - | 2e-09 | 24.81% (262) | hypothetical protein MUL_3695 |
| M. vanbaalenii PYR-1 | Mvan_4196 | - | 1e-120 | 78.97% (271) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3752|M.marinum_M ------------------MSVPARS----------VPLFADIADVSRRLA
MUL_3695|M.ulcerans_Agy99 ------------------MSVPARS----------VPLFADIADVSRRLA
Mb2450c|M.bovis_AF2122/97 ------------------MTVPARP----------TPLFADIADVSRRLA
Rv2426c|M.tuberculosis_H37Rv ------------------MTVPARP----------TPLFADIADVSRRLA
MAB_1619|M.abscessus_ATCC_1997 ------------------MSDPLRPSGSSQSRTQTAPLFTSIDDVTTRLA
Mflv_2458|M.gilvum_PYR-GCK -----------------------------------MSVTNSSSGVRSSSR
MSMEG_6809|M.smegmatis_MC2_155 ---------------------------------------MSDAAVVLENR
Mvan_4196|M.vanbaalenii_PYR-1 -----------------------------------MTVNNFRLTTEAGSP
MAV_1270|M.avium_104 -----------------------------------MVDQSGLAYVHAAEA
TH_4050|M.thermoresistible__bu ------------------------------------------------LT
MLBr_01810|M.leprae_Br4923 MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADGLVAEVHTLERAIFEV
MMAR_3752|M.marinum_M QTGYLPDTATATAVFLADRLGKPLLVEGPAGVGKTELARAVAQATGSGLV
MUL_3695|M.ulcerans_Agy99 QTGYLPDTATATAVFLADRLGKPLLVEGPAGVGKTELARAVAQATGSGLV
Mb2450c|M.bovis_AF2122/97 ETGYLPDTATATAVFLADRLGKPLLVEGPAGVGKTELARAVAQATGSGLV
Rv2426c|M.tuberculosis_H37Rv ETGYLPDTATATAVFLADRLGKPLLVEGPAGVGKTELARAVAQATGSGLV
MAB_1619|M.abscessus_ATCC_1997 ETGYLADTATATAVFLADRLGKPLLVEGPAGVGKTELARAVAHTTGSGLV
Mflv_2458|M.gilvum_PYR-GCK APFYRAVGDEVEVFRAAARRGLPVLLKGPTGCGKTRFVEAVAHELGRDLI
MSMEG_6809|M.smegmatis_MC2_155 SPFYVPVADEAEVFRAAARRGTPVLLKGPTGCGKTRFVESMAHELGRDLI
Mvan_4196|M.vanbaalenii_PYR-1 APFYRAAGPEVEIFRAAARRGSPVLLKGPTGCGKTRFVEAMAHDLGRELI
MAV_1270|M.avium_104 RPYYRAVGSEEAVFKAAYRQGLALVLKGPTGCGKTRFVEAMAYDLGRPLI
TH_4050|M.thermoresistible__bu AKTYFSNGDEVRLFEQAYRQRLPVMLTGPTGCGKTRLIEHMGALLGRPVV
MLBr_01810|M.leprae_Br4923 KRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTFA
. . ::: * .* .** . .. * .
MMAR_3752|M.marinum_M RLQCYEGVDEARALYEWN-HAKQ-----------ILRIQSGSGDWEATKD
MUL_3695|M.ulcerans_Agy99 RLQCYEGVDEARALYEWN-HAKQ-----------ILRIQSGSGDWEATKD
Mb2450c|M.bovis_AF2122/97 RLQCYEGVDEARALYEWN-HAKQ-----------ILRIQAGSGDWEATKT
Rv2426c|M.tuberculosis_H37Rv RLQCYEGVDEARALYEWN-HAKQ-----------ILRIQAGSGDWEATKT
MAB_1619|M.abscessus_ATCC_1997 RLQCYEGVDEARALYEWN-HAKQ-----------ILRIQAGSGDWDETKT
Mflv_2458|M.gilvum_PYR-GCK TVAGHEDMTSADLVGRFLLKGGE-----------TVWVDGPLTRAVRTGA
MSMEG_6809|M.smegmatis_MC2_155 TVAGHEDMTSADLVGRFLLKGGE-----------TIWVDGPLTRAVRTGA
Mvan_4196|M.vanbaalenii_PYR-1 TVAGHEDMTSADLVGRFLLKGGE-----------TVWVDGPLTRAVREGA
MAV_1270|M.avium_104 TVACHDDLTTADLVGRYLLRGDE-----------TVWVDGPLTRAVREGA
TH_4050|M.thermoresistible__bu TISCHDDLTSADLVGRFMVTGGD-----------VVWTDGPLTRAVKEGA
MLBr_01810|M.leprae_Br4923 RIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLADEINRAPAKV
: .: : : . .
MMAR_3752|M.marinum_M DVFSEEFLLQRPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSD---
MUL_3695|M.ulcerans_Agy99 DVFSEEFLLQRPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSD---
Mb2450c|M.bovis_AF2122/97 DVLSEEFLLQRPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSD---
Rv2426c|M.tuberculosis_H37Rv DVFSEEFLLQRPLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLSD---
MAB_1619|M.abscessus_ATCC_1997 DVFAEEFLLSRPLLTAIRREDPTVLLIDETDKADIEIEGLLLEVLSD---
Mflv_2458|M.gilvum_PYR-GCK LCYLDEIVEARQDTTVVIHP-----LADHRRELPVDRLGVTVPAAPG---
MSMEG_6809|M.smegmatis_MC2_155 ICYLDEIVEARQDTTVVIHP-----LADHRRELPIDRLGTTLSAVPG---
Mvan_4196|M.vanbaalenii_PYR-1 ICYLDEIVEARQDTTVVIHP-----LADHRRELPIDRLGTTLSAAPG---
MAV_1270|M.avium_104 ICYLDEVVEARQDTTVVLHP-----LADHRRQLPIERLGITLDAAPG---
TH_4050|M.thermoresistible__bu ICYLDEVVEARHDSLAVLHS-----LTDHRRTLYLDRAGEVVAAPEN---
MLBr_01810|M.leprae_Br4923 QSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQRDR
*.: * : :: * :
MMAR_3752|M.marinum_M --FAVTVPELG-----------TLTAARAPFVLLTSNATRELSEALKRRC
MUL_3695|M.ulcerans_Agy99 --FAVTVPELG-----------TLTATRAPFVLLTSNATRELSEALKRRC
Mb2450c|M.bovis_AF2122/97 --FAVTVPELG-----------TLTATRAPFVLLTSNATRELSEALKRRC
Rv2426c|M.tuberculosis_H37Rv --FAVTVPELG-----------TLTATRAPFVLLTSNATRELSEALKRRC
MAB_1619|M.abscessus_ATCC_1997 --FAVTIPELG-----------TIAASRKPFVLLTSNATRELSEALKRRC
Mflv_2458|M.gilvum_PYR-GCK --FQLVISYNP-----------GYQS-----------VLKNIKESTRQRF
MSMEG_6809|M.smegmatis_MC2_155 --FQLVISYNP-----------GYQS-----------VLKSIKESTRQRF
Mvan_4196|M.vanbaalenii_PYR-1 --FQLVISYNP-----------GYQS-----------ILKSLKDSTRQRF
MAV_1270|M.avium_104 --FGLVVSYNP-----------GYQS-----------VLKDLKDSTRQRM
TH_4050|M.thermoresistible__bu --FMLVCSYNP-----------AYRS-----------SLKDLKPSFRQRF
MLBr_01810|M.leprae_Br4923 FLFKINVGYPSPEEEREIIYRMGVTPPVPKQILNAGDLLRLQEISANNFV
* : . : . : ..
MMAR_3752|M.marinum_M LFLHIDFPT--------------PEMERRILLSRVP-----ELPEHIAEE
MUL_3695|M.ulcerans_Agy99 LFLHIDFPT--------------PEMERRILLSRVP-----ELPEHIAEE
Mb2450c|M.bovis_AF2122/97 LYLHIDFPT--------------PELERRILLSRVP-----ELPEHFAEE
Rv2426c|M.tuberculosis_H37Rv LYLHIDFPT--------------PELERRILLSRVP-----ELPEHFAEE
MAB_1619|M.abscessus_ATCC_1997 LFLHIDFPD--------------AELERRILLKRVP-----ELPASLAEE
Mflv_2458|M.gilvum_PYR-GCK IAIELDFPP--------------PDAETEIVAHEA------GIDPDTARV
MSMEG_6809|M.smegmatis_MC2_155 IAIELDFPP--------------PHVETEIVAHEA------GVDADTARA
Mvan_4196|M.vanbaalenii_PYR-1 VAISLDFPA--------------AEIETEVVAQEA------GIDESTAGS
MAV_1270|M.avium_104 VAIEFDFPA--------------ADVEEGIVAHEA------GVDAATAAE
TH_4050|M.thermoresistible__bu VTLPMSYLP--------------PEREAEVIVAET------GVPLAVARR
MLBr_01810|M.leprae_Br4923 HHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLGIIKASRSLA
..: . : : : :
MMAR_3752|M.marinum_M LVRIIGVLRGMQLKKLPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVL
MUL_3695|M.ulcerans_Agy99 LVRIIGVLRGMQLKKLPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVL
Mb2450c|M.bovis_AF2122/97 LVRIIGVLRGMQLKKVPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVL
Rv2426c|M.tuberculosis_H37Rv LVRIIGVLRGMQLKKVPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVL
MAB_1619|M.abscessus_ATCC_1997 LVRIIGVLRNMQLKKVPSVAETIDWGRTILALGLDTLDDAVIASTLGVVL
Mflv_2458|M.gilvum_PYR-GCK LVRIGNAIRNIDGSPLREVSSTRMLILAGGLVAEGLGLRRAVQAAIVETL
MSMEG_6809|M.smegmatis_MC2_155 LVSVGAAIRNIDGSPLREVASTRMLILAGGLVAEGLPLRRAVRAAIVEAL
Mvan_4196|M.vanbaalenii_PYR-1 LVALGNAIRNLDGAALSEVASTRMLILAGGLVAEGLHLLDAVQSAVVEVL
MAV_1270|M.avium_104 LVRFGQAIRRLETAGLREVASTRVLIAAGRLIAEGLSLPEAARAAIAGPL
TH_4050|M.thermoresistible__bu LVQCAVAIRTADAAFHFEPPSTRVLVTAGHLIAAGAGELDAAEACILAPL
MLBr_01810|M.leprae_Br4923 LVRGRDYVIPQDVIEVIPDVLRHRLVLTYNALADEISPEIVINRVLQTVA
** : : : :. . :
MMAR_3752|M.marinum_M KHQSDQQRATGELRLN------------
MUL_3695|M.ulcerans_Agy99 KHQSDQQRATGELRLN------------
Mb2450c|M.bovis_AF2122/97 KHQSDQQRATGELRLN------------
Rv2426c|M.tuberculosis_H37Rv KHQSDQQRATGELRLN------------
MAB_1619|M.abscessus_ATCC_1997 KHHSDQQRAAGELRLN------------
Mflv_2458|M.gilvum_PYR-GCK SDDGDVIRALGELVDALLPAP-------
MSMEG_6809|M.smegmatis_MC2_155 SDDHDIIRALGELVDAHLP---------
Mvan_4196|M.vanbaalenii_PYR-1 SDDPDVIRGLGELVDAVLPRR-------
MAV_1270|M.avium_104 TDDVAVGKALGEMIGIYFGSGGSLGSAD
TH_4050|M.thermoresistible__bu SSDGAVGDGLREVAVACLTGADSSS---
MLBr_01810|M.leprae_Br4923 LPQVNSFPQQGHSVPSVTQAAAAASGR-
. .