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VTVPARPTPLFADIADVSRRLAETGYLPDTATATAVFLADRLGKPLLVEGPAGVGKTELARAVAQATGSG LVRLQCYEGVDEARALYEWNHAKQILRIQAGSGDWEATKTDVLSEEFLLQRPLLTAIRRTEPTVLLIDET DKADIEIEGLLLEVLSDFAVTVPELGTLTATRAPFVLLTSNATRELSEALKRRCLYLHIDFPTPELERRI LLSRVPELPEHFAEELVRIIGVLRGMQLKKVPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSD QQRATGELRLN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2450c | - | - | 100% (291) | hypothetical protein Mb2450c |
| M. bovis AF2122 / 97 | Mb0377c | - | 1e-59 | 44.64% (280) | oxidoreductase |
| M. bovis AF2122 / 97 | Mb3640c | ftsH | 8e-05 | 33.33% (96) | membrane-bound protease FTSH (cell division protein) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2645 | - | 1e-143 | 87.63% (291) | ATPase |
| M. tuberculosis H37Rv | Rv2426c | - | 1e-161 | 99.66% (291) | hypothetical protein Rv2426c |
| M. leprae Br4923 | MLBr_00222 | ftsH | 4e-05 | 33.33% (96) | putative integral membrane peptidase |
| M. abscessus ATCC 19977 | MAB_1619 | - | 1e-139 | 87.63% (283) | hypothetical protein MAB_1619 |
| M. marinum M | MMAR_3752 | - | 1e-155 | 95.88% (291) | hypothetical protein MMAR_3752 |
| M. avium 104 | MAV_1748 | - | 1e-153 | 94.50% (291) | ATPase associated with various cellular activities |
| M. smegmatis MC2 155 | MSMEG_4583 | - | 1e-144 | 86.91% (298) | ATPase associated with various cellular activities |
| M. thermoresistible (build 8) | TH_0791 | - | 1e-142 | 86.49% (296) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3695 | - | 1e-156 | 96.22% (291) | hypothetical protein MUL_3695 |
| M. vanbaalenii PYR-1 | Mvan_3933 | - | 1e-142 | 86.39% (294) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 MLLMNRKNVIRMVTAIAVVVLLGWSFFYFSDDTRGYKFVDTSVAMSQING
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 HNVKSAQIDDREQQLRLTLKKGNNDTDGSDKVITKYPTGYAVDLFNALSA
Mflv_2645|M.gilvum_PYR-GCK -------------------------------------MSVPASI------
Mvan_3933|M.vanbaalenii_PYR-1 -------------------------------------MSVPAQT------
Mb2450c|M.bovis_AF2122/97 -------------------------------------MTVPARP------
Rv2426c|M.tuberculosis_H37Rv -------------------------------------MTVPARP------
MMAR_3752|M.marinum_M -------------------------------------MSVPARS------
MUL_3695|M.ulcerans_Agy99 -------------------------------------MSVPARS------
MAV_1748|M.avium_104 -------------------------------------MSVPARP------
MAB_1619|M.abscessus_ATCC_1997 -------------------------------------MSDPLRPSG----
MSMEG_4583|M.smegmatis_MC2_155 -------------------------------------MSVPARP------
TH_0791|M.thermoresistible__bu -------------------------------------VSLPARS------
MLBr_00222|M.leprae_Br4923 KNTKVTTAVNEGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGK
:
Mflv_2645|M.gilvum_PYR-GCK -----------QPLFADIDDVARRLAETGYLPDTAT--ATAVFLADRLGK
Mvan_3933|M.vanbaalenii_PYR-1 -----------VPLFADIDDVARRLAETGYLPDTAT--ATAVFLADRLGK
Mb2450c|M.bovis_AF2122/97 -----------TPLFADIADVSRRLAETGYLPDTAT--ATAVFLADRLGK
Rv2426c|M.tuberculosis_H37Rv -----------TPLFADIADVSRRLAETGYLPDTAT--ATAVFLADRLGK
MMAR_3752|M.marinum_M -----------VPLFADIADVSRRLAQTGYLPDTAT--ATAVFLADRLGK
MUL_3695|M.ulcerans_Agy99 -----------VPLFADIADVSRRLAQTGYLPDTAT--ATAVFLADRLGK
MAV_1748|M.avium_104 -----------RPLFADIDDVSRRLAETGYLPDTAT--ATAVFLADRLGK
MAB_1619|M.abscessus_ATCC_1997 ---SSQSRTQTAPLFTSIDDVTTRLAETGYLADTAT--ATAVFLADRLGK
MSMEG_4583|M.smegmatis_MC2_155 -----------APLFADIDDVARKLAETGYLPDTAT--ATAVFLADRLGK
TH_0791|M.thermoresistible__bu -----------APLFADIDDVSRRLAETGYLPDTAT--ATAVYLADRLGK
MLBr_00222|M.leprae_Br4923 SRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPCRYQTLGAKIPK
. *:.: .* : : : * . *. :: *
Mflv_2645|M.gilvum_PYR-GCK PLLVEGPAGVGKTELARAIAQST--------GSGLVRLQCYEGVDESRAL
Mvan_3933|M.vanbaalenii_PYR-1 PLLVEGPAGVGKTELARAIAQST--------GSELVRLQCYEGVDESRAL
Mb2450c|M.bovis_AF2122/97 PLLVEGPAGVGKTELARAVAQAT--------GSGLVRLQCYEGVDEARAL
Rv2426c|M.tuberculosis_H37Rv PLLVEGPAGVGKTELARAVAQAT--------GSGLVRLQCYEGVDEARAL
MMAR_3752|M.marinum_M PLLVEGPAGVGKTELARAVAQAT--------GSGLVRLQCYEGVDEARAL
MUL_3695|M.ulcerans_Agy99 PLLVEGPAGVGKTELARAVAQAT--------GSGLVRLQCYEGVDEARAL
MAV_1748|M.avium_104 PLLVEGPAGVGKTELARAVAQAT--------GSGLVRLQCYEGVDEARAL
MAB_1619|M.abscessus_ATCC_1997 PLLVEGPAGVGKTELARAVAHTT--------GSGLVRLQCYEGVDEARAL
MSMEG_4583|M.smegmatis_MC2_155 PLLVEGPAGVGKTELARAVAQCT--------GSELVRLQCYEGVDEARAL
TH_0791|M.thermoresistible__bu PLLVEGPAGVGKTELARAVAQAT--------GSELVRLQCYEGVDEARAL
MLBr_00222|M.leprae_Br4923 GVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDL
:*: **.*.*** ****:* : ** :*.: *... * *
Mflv_2645|M.gilvum_PYR-GCK YEWN---------------------------------HAKQILRIQAGHG
Mvan_3933|M.vanbaalenii_PYR-1 YEWN---------------------------------HAKQILRIQAGQG
Mb2450c|M.bovis_AF2122/97 YEWN---------------------------------HAKQILRIQAGSG
Rv2426c|M.tuberculosis_H37Rv YEWN---------------------------------HAKQILRIQAGSG
MMAR_3752|M.marinum_M YEWN---------------------------------HAKQILRIQSGSG
MUL_3695|M.ulcerans_Agy99 YEWN---------------------------------HAKQILRIQSGSG
MAV_1748|M.avium_104 YEWN---------------------------------HAKQILRIQAGSG
MAB_1619|M.abscessus_ATCC_1997 YEWN---------------------------------HAKQILRIQAGSG
MSMEG_4583|M.smegmatis_MC2_155 YEWN---------------------------------HAKQILRIQAGNA
TH_0791|M.thermoresistible__bu YEWN---------------------------------HAKQILRIQAGNA
MLBr_00222|M.leprae_Br4923 FDQAKQNSPCIIFVDEIDAVGRQRGTGLGGGHDEREQTLNQLLVEMDGFG
:: :*:* * .
Mflv_2645|M.gilvum_PYR-GCK -------DWDQTRDDVFSEEFLLTRPLLTAIRRTEP------TVLLIDET
Mvan_3933|M.vanbaalenii_PYR-1 EGA----DWDRTKDDVFSEEFLLTRPLLTAIRRTEP------TVLLIDET
Mb2450c|M.bovis_AF2122/97 -------DWEATKTDVLSEEFLLQRPLLTAIRRTEP------TVLLIDET
Rv2426c|M.tuberculosis_H37Rv -------DWEATKTDVFSEEFLLQRPLLTAIRRTEP------TVLLIDET
MMAR_3752|M.marinum_M -------DWEATKDDVFSEEFLLQRPLLTAIRRTEP------TVLLIDET
MUL_3695|M.ulcerans_Agy99 -------DWEATKDDVFSEEFLLQRPLLTAIRRTEP------TVLLIDET
MAV_1748|M.avium_104 -------DWDQTKTDVFSEEFLLQRPLLTAIRRTEP------TVLLIDET
MAB_1619|M.abscessus_ATCC_1997 -------DWDETKTDVFAEEFLLSRPLLTAIRREDP------TVLLIDET
MSMEG_4583|M.smegmatis_MC2_155 AAAGDSDAWEQTKTDVFSEEFLLTRPLLTAIKRTDP------TVLLIDET
TH_0791|M.thermoresistible__bu GAGG--EAWERTKDDVFSEEFLLSRPLLTAIRRTEP------TVLLIDET
MLBr_00222|M.leprae_Br4923 DRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHSK
.: *:: :* : * :* :** :...
Mflv_2645|M.gilvum_PYR-GCK DK---ADIEIEGLLLEVL----SDFAVTVPELGTITAERRPLVVLT----
Mvan_3933|M.vanbaalenii_PYR-1 DK---ADIEIEGLLLEVL----SDFAVTVPELGTITAERRPLVVLT----
Mb2450c|M.bovis_AF2122/97 DK---ADIEIEGLLLEVL----SDFAVTVPELGTLTATRAPFVLLT----
Rv2426c|M.tuberculosis_H37Rv DK---ADIEIEGLLLEVL----SDFAVTVPELGTLTATRAPFVLLT----
MMAR_3752|M.marinum_M DK---ADIEIEGLLLEVL----SDFAVTVPELGTLTAARAPFVLLT----
MUL_3695|M.ulcerans_Agy99 DK---ADIEIEGLLLEVL----SDFAVTVPELGTLTATRAPFVLLT----
MAV_1748|M.avium_104 DK---ADIEIEGLLLEVL----SDFAVTVPELGTLTAERPPFVVLT----
MAB_1619|M.abscessus_ATCC_1997 DK---ADIEIEGLLLEVL----SDFAVTIPELGTIAASRKPFVLLT----
MSMEG_4583|M.smegmatis_MC2_155 DK---ADIEIEGLLLEVL----SDFAVTVPELGTITAERPPFVVLT----
TH_0791|M.thermoresistible__bu DK---ADIEIEGLLLEVL----SDFAVTVPELGTITAERIPFVVLT----
MLBr_00222|M.leprae_Br4923 GKPIADDADLDGLAKRTVGMTGADLANVVNEAALLTARENGLVITGPALE
.* * :::** ..: :*:* .: * . ::* . :*:
Mflv_2645|M.gilvum_PYR-GCK -----------------SNATRELSEALKRRCLFLHIDFPDPD-LERRIL
Mvan_3933|M.vanbaalenii_PYR-1 -----------------SNATRELSEALKRRCLFLHIDFPDPD-LERRIL
Mb2450c|M.bovis_AF2122/97 -----------------SNATRELSEALKRRCLYLHIDFPTPE-LERRIL
Rv2426c|M.tuberculosis_H37Rv -----------------SNATRELSEALKRRCLYLHIDFPTPE-LERRIL
MMAR_3752|M.marinum_M -----------------SNATRELSEALKRRCLFLHIDFPTPE-MERRIL
MUL_3695|M.ulcerans_Agy99 -----------------SNATRELSEALKRRCLFLHIDFPTPE-MERRIL
MAV_1748|M.avium_104 -----------------SNATRELSEALKRRCLFLHIDFPSPD-LERRIL
MAB_1619|M.abscessus_ATCC_1997 -----------------SNATRELSEALKRRCLFLHIDFPDAE-LERRIL
MSMEG_4583|M.smegmatis_MC2_155 -----------------SNATRELSEALKRRCLFLHIDFPDPD-LERRIL
TH_0791|M.thermoresistible__bu -----------------SNATRELSEALKRRCLFLHIDFPDPD-LERRIL
MLBr_00222|M.leprae_Br4923 EAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTI
*: :::: : :* : : : :
Mflv_2645|M.gilvum_PYR-GCK LSR---------VPELP------ERLAEELVRIIG-------VLRGMQLK
Mvan_3933|M.vanbaalenii_PYR-1 LSR---------VPELP------ERLAEELVRIIG-------VLRGMALK
Mb2450c|M.bovis_AF2122/97 LSR---------VPELP------EHFAEELVRIIG-------VLRGMQLK
Rv2426c|M.tuberculosis_H37Rv LSR---------VPELP------EHFAEELVRIIG-------VLRGMQLK
MMAR_3752|M.marinum_M LSR---------VPELP------EHIAEELVRIIG-------VLRGMQLK
MUL_3695|M.ulcerans_Agy99 LSR---------VPELP------EHIAEELVRIIG-------VLRGMQLK
MAV_1748|M.avium_104 LSR---------VPELP------AHLADELVRIIG-------VLRGMQLK
MAB_1619|M.abscessus_ATCC_1997 LKR---------VPELP------ASLAEELVRIIG-------VLRNMQLK
MSMEG_4583|M.smegmatis_MC2_155 LSR---------VPELP------EHIASELVRIIG-------VLRGMQLK
TH_0791|M.thermoresistible__bu LSR---------VPELP------ERIASELVRIVG-------VLRGMQLK
MLBr_00222|M.leprae_Br4923 LARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTTG
* * *** : :** :* *:*
Mflv_2645|M.gilvum_PYR-GCK KLPSVAETIDWAR-TVLALGMDT----------IDDEVIAATLGVVLKHQ
Mvan_3933|M.vanbaalenii_PYR-1 KLPSVAETIDWGR-TLLALGMDT----------VDDEVIAATLGVVLKHQ
Mb2450c|M.bovis_AF2122/97 KVPSIAETIDWGR-TVLALGLDT----------IDDAVVAATLGVVLKHQ
Rv2426c|M.tuberculosis_H37Rv KVPSIAETIDWGR-TVLALGLDT----------IDDAVVAATLGVVLKHQ
MMAR_3752|M.marinum_M KLPSIAETIDWGR-TVLALGLDT----------IDDAVVAATLGVVLKHQ
MUL_3695|M.ulcerans_Agy99 KLPSIAETIDWGR-TVLALGLDT----------IDDAVVAATLGVVLKHQ
MAV_1748|M.avium_104 KVPSIAETIDWGR-TLLALGLDT----------IDDAVVAATLGVVLKHQ
MAB_1619|M.abscessus_ATCC_1997 KVPSVAETIDWGR-TILALGLDT----------LDDAVIASTLGVVLKHH
MSMEG_4583|M.smegmatis_MC2_155 KLPSVAETIDWGR-TVLALGMDT----------IDDEMIAATLGVILKHQ
TH_0791|M.thermoresistible__bu KLPSVAETIDWAR-TVLALGMDT----------IDDEMIAATLGVVLKHQ
MLBr_00222|M.leprae_Br4923 AVSDIEKATKIARSMVTEFGMSSKLGAVRYGSEHGDPFLGRTMGTQADYS
:..: :: . .* : :*:.: .* .:. *:*. .:
Mflv_2645|M.gilvum_PYR-GCK SDQIKAAGELRLN-------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 SDQIKASGELRLN-------------------------------------
Mb2450c|M.bovis_AF2122/97 SDQQRATGELRLN-------------------------------------
Rv2426c|M.tuberculosis_H37Rv SDQQRATGELRLN-------------------------------------
MMAR_3752|M.marinum_M SDQQRATGELRLN-------------------------------------
MUL_3695|M.ulcerans_Agy99 SDQQRATGELRLN-------------------------------------
MAV_1748|M.avium_104 SDQQRATGELRLN-------------------------------------
MAB_1619|M.abscessus_ATCC_1997 SDQQRAAGELRLN-------------------------------------
MSMEG_4583|M.smegmatis_MC2_155 SDQQRAAGELKLN-------------------------------------
TH_0791|M.thermoresistible__bu SDQQRAISELKLN-------------------------------------
MLBr_00222|M.leprae_Br4923 HEVARDIDDEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPE
: : .: :
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 LEGIFASVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPVP
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 EPAFKAAIARASQAAEASHQAAQSDTDGPPGQGANGSHAGDRQRQHGPTQ
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 PDYGAPPGWHAPGWPPQQPPDYWYPPEQQPSQSPYWPQPAPSYPGQAPPP
Mflv_2645|M.gilvum_PYR-GCK ----------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 ----------------------------------------
Mb2450c|M.bovis_AF2122/97 ----------------------------------------
Rv2426c|M.tuberculosis_H37Rv ----------------------------------------
MMAR_3752|M.marinum_M ----------------------------------------
MUL_3695|M.ulcerans_Agy99 ----------------------------------------
MAV_1748|M.avium_104 ----------------------------------------
MAB_1619|M.abscessus_ATCC_1997 ----------------------------------------
MSMEG_4583|M.smegmatis_MC2_155 ----------------------------------------
TH_0791|M.thermoresistible__bu ----------------------------------------
MLBr_00222|M.leprae_Br4923 YPSYPPCPSYPPPGQSAPDAGKPPAQLDEGVSPSNPPAHG