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TDTYLANGTEVQLFEQAYRQRLPVMLTGPTGCGKTRLVEHMGLLLGRPVVTISCHDDLTSSDLVGRFMVT GGDVTWTDGPLTRAVKTGTICYLDEVVEARHDSLAVLHSLTDHRRTLYLDRAGEVVAAPETFMLVCSYNP AYRSSLKELKPSFRQRFVTLPMRYLPPEREAEVIVAETGVATATAERLVRCATAIRTADEAFHFEPPSTR VLVTAAQLIAAGATELEAAEACVLAPLSSDGAIAEGLREVAAAGLAAAGNPSPNR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1772 | - | - | 100% (266) | ATPase |
| M. gilvum PYR-GCK | Mflv_2458 | - | 6e-66 | 49.21% (254) | ATPase |
| M. gilvum PYR-GCK | Mflv_4155 | - | 5e-65 | 51.42% (247) | ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1515 | moxR1 | 3e-05 | 24.31% (181) | transcriptional regulatory protein MOXR1 |
| M. tuberculosis H37Rv | Rv1479 | moxR1 | 3e-05 | 24.31% (181) | transcriptional regulatory protein MOXR1 |
| M. leprae Br4923 | MLBr_01810 | moxR | 4e-05 | 23.56% (174) | MoxR homolog |
| M. abscessus ATCC 19977 | MAB_0653 | - | 2e-05 | 25.77% (163) | MoxR-like ATPase |
| M. marinum M | MMAR_2286 | moxR1 | 2e-05 | 23.04% (230) | transcriptional regulatory protein, MoxR1 |
| M. avium 104 | MAV_2455 | - | 1e-129 | 86.31% (263) | CbbQ/NirQ/NorQ/GpvN family protein |
| M. smegmatis MC2 155 | MSMEG_6809 | cbbQ | 7e-63 | 48.02% (252) | CbbQ protein |
| M. thermoresistible (build 8) | TH_4050 | - | 1e-128 | 86.54% (260) | PUTATIVE ATPase associated with various cellular activities, |
| M. ulcerans Agy99 | MUL_1488 | moxR1 | 1e-05 | 23.04% (230) | transcriptional regulatory protein, MoxR1 |
| M. vanbaalenii PYR-1 | Mvan_4975 | - | 1e-134 | 89.73% (263) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2286|M.marinum_M MTSAG------GGYSGPGGHSAPPAHEAPSGGPDGLAAEVHTLERAIFEV
MUL_1488|M.ulcerans_Agy99 MTSAG------GGYSGPGGHSAPPAHEAPSGGPDGLAAEVHTLERAIFEV
Mb1515|M.bovis_AF2122/97 MTSAGGFPAGAGGYQTPGGHSASPAHEAPPGGAEGLAAEVHTLERAIFEV
Rv1479|M.tuberculosis_H37Rv MTSAGGFPAGAGGYQTPGGHSASPAHEAPPGGAEGLAAEVHTLERAIFEV
MLBr_01810|M.leprae_Br4923 MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADGLVAEVHTLERAIFEV
MAB_0653|M.abscessus_ATCC_1997 MTAAT--------------QTQPSRQELDQAR-----AVIQAVARA-FSV
Mflv_1772|M.gilvum_PYR-GCK ------------------------------------------------MT
Mvan_4975|M.vanbaalenii_PYR-1 ------------------------------------------------MT
MAV_2455|M.avium_104 ------------------------------------------------MT
TH_4050|M.thermoresistible__bu ------------------------------------------------LT
MSMEG_6809|M.smegmatis_MC2_155 ---------------------------------------MSDAAVVLENR
MMAR_2286|M.marinum_M KRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLAVETFARVVGGSFA
MUL_1488|M.ulcerans_Agy99 KRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLAVETFARVVGGSFA
Mb1515|M.bovis_AF2122/97 KRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTFS
Rv1479|M.tuberculosis_H37Rv KRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTFS
MLBr_01810|M.leprae_Br4923 KRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTFA
MAB_0653|M.abscessus_ATCC_1997 K--VVGQSGLQQSLLIGLLTGGHVLLESVPGLAKTTAARAIADAIQAQFR
Mflv_1772|M.gilvum_PYR-GCK D-TYLANGTEVQLFEQAYRQRLPVMLTGPTGCGKTRLVEHMGLLLGRPVV
Mvan_4975|M.vanbaalenii_PYR-1 EQTYLANGNEVRLFEQACRQRLPVMLTGPTGCGKTRLVEHMGLLLGRPVV
MAV_2455|M.avium_104 TDTYFANGNEVQLFEQAFARRLPVMLTGPTGCGKTRFVEHMGSLLQRPVV
TH_4050|M.thermoresistible__bu AKTYFSNGDEVRLFEQAYRQRLPVMLTGPTGCGKTRLIEHMGALLGRPVV
MSMEG_6809|M.smegmatis_MC2_155 SPFYVPVADEAEVFRAAARRGTPVLLKGPTGCGKTRFVESMAHELGRDLI
. . : . *:* . .* .** . :. : .
MMAR_2286|M.marinum_M RIQFTPDLVPTDIVGTRIYRQGKEEFDT---ELGPVVANFLLADEINRAP
MUL_1488|M.ulcerans_Agy99 RIQFTPDLVPTDIVGTRIYRQGKEEFDT---ELGPVVANFLLADEINRAP
Mb1515|M.bovis_AF2122/97 RIQFTPDLVPTDIIGTRIYRQGREEFDT---ELGPVVANFLLADEINRAP
Rv1479|M.tuberculosis_H37Rv RIQFTPDLVPTDIIGTRIYRQGREEFDT---ELGPVVANFLLADEINRAP
MLBr_01810|M.leprae_Br4923 RIQFTPDLVPTDIIGTRIYRQGKEEFDT---ELGPVVVNFLLADEINRAP
MAB_0653|M.abscessus_ATCC_1997 RIQCTPDLLPSDIIGTQIFDASKGTFKT---QLGPVHANIVLLDEINRSS
Mflv_1772|M.gilvum_PYR-GCK TISCHDDLTSSDLVGRFMVTGGDVTWTDGPLTRAVKTGTICYLDEVVEAR
Mvan_4975|M.vanbaalenii_PYR-1 TISCHDDLTSSDLVGRFIVTGGDVVWTDGPLTRAVKAGAICYLDEVVEAR
MAV_2455|M.avium_104 TISCHDDLTSSDLVGRFMVTGGDVVWTDGPLTRAVKAGAICYLDEVVEAR
TH_4050|M.thermoresistible__bu TISCHDDLTSADLVGRFMVTGGDVVWTDGPLTRAVKEGAICYLDEVVEAR
MSMEG_6809|M.smegmatis_MC2_155 TVAGHEDMTSADLVGRFLLKGGETIWVDGPLTRAVRTGAICYLDEIVEAR
: *: .:*::* : . : . : **: .:
MMAR_2286|M.marinum_M AKVQSALLEVMAER---HVSIGGKTFPMPNPFLVMATQNPIEQEGVYPLP
MUL_1488|M.ulcerans_Agy99 AKVQSALLEVMAER---HVSIGGKTFPMPNPFLVMATQNPIEQEGVYPLP
Mb1515|M.bovis_AF2122/97 AKVQSALLEVMQER---HVSIGGRTFPMPSPFLVMATQNPIEHEGVYPLP
Rv1479|M.tuberculosis_H37Rv AKVQSALLEVMQER---HVSIGGRTFPMPSPFLVMATQNPIEHEGVYPLP
MLBr_01810|M.leprae_Br4923 AKVQSALLEVMQER---HVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLP
MAB_0653|M.abscessus_ATCC_1997 AKTQSAMLEAMEER---QTSIAGEIYKIPEPFLVLATQNPVDQEGTYPLP
Mflv_1772|M.gilvum_PYR-GCK HDSLAVLHSLTDHRRTLYLDRAGEVVAAPETFMLVCSYNPAYRSSLKELK
Mvan_4975|M.vanbaalenii_PYR-1 HDSLAVLHSLTDHRRTLYLDRAGEVVRAPEEFMLVCSYNPAYRSSLKELK
MAV_2455|M.avium_104 HDSLAILHSLTDHRRSLYLDRAGEVVKAPEGFMLVCSYNPAYRSSLKELK
TH_4050|M.thermoresistible__bu HDSLAVLHSLTDHRRTLYLDRAGEVVAAPENFMLVCSYNPAYRSSLKDLK
MSMEG_6809|M.smegmatis_MC2_155 QDTTVVIHPLADHRRELPIDRLGTTLSAVPGFQLVISYNPGYQSVLKSIK
. : .* . * * :: : ** :. :
MMAR_2286|M.marinum_M EAQRDRFLFKINVGYPTPEEEREIIYRMGV---TPPQPKQILGTGDLLRL
MUL_1488|M.ulcerans_Agy99 EAQRDRFLFKINVGYPTPEEEREIIYRMGV---TPPQPKQILGTGDLLRL
Mb1515|M.bovis_AF2122/97 EAQRDRFLFKINVGYPSPEEEREIIYRMGV---TPPQAKQILSTGDLLRL
Rv1479|M.tuberculosis_H37Rv EAQRDRFLFKINVGYPSPEEEREIIYRMGV---TPPQAKQILSTGDLLRL
MLBr_01810|M.leprae_Br4923 EAQRDRFLFKINVGYPSPEEEREIIYRMGV---TPPVPKQILNAGDLLRL
MAB_0653|M.abscessus_ATCC_1997 EAQMDRFMFKEILTYPNPAEEAEVVFRIDAGVYTNHQGAPVASIQDILYI
Mflv_1772|M.gilvum_PYR-GCK PSFRQRFVTLP-MRYLPPEREAEVIVAETG-------------------V
Mvan_4975|M.vanbaalenii_PYR-1 PSFRQRFVTLP-MCYLPPDREAEVIVAEAG-------------------I
MAV_2455|M.avium_104 PSFRQRFVTLA-MHYLPPDREADVIVAESG-------------------I
TH_4050|M.thermoresistible__bu PSFRQRFVTLP-MSYLPPEREAEVIVAETG-------------------V
MSMEG_6809|M.smegmatis_MC2_155 ESTRQRFIAIE-LDFPPPHVETEIVAHEAG-------------------V
: :**: : : * * ::: :
MMAR_2286|M.marinum_M QDIAANNFVHHALVDYVVRVVMATRQPEQLGMNDVKTWIAFGASPRASLG
MUL_1488|M.ulcerans_Agy99 QDIAANNFVHHALVDYVVRVVMATRQPEQLGMNDVKTWIAFGASPRASLG
Mb1515|M.bovis_AF2122/97 QEIAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPRASLG
Rv1479|M.tuberculosis_H37Rv QEIAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPRASLG
MLBr_01810|M.leprae_Br4923 QEISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLG
MAB_0653|M.abscessus_ATCC_1997 QDVVRRIYVDPAIVHYVTQIVNVTRNPKQYLPPNLARLIEYGASPRATIA
Mflv_1772|M.gilvum_PYR-GCK ATATAERLVRCATAIRTADEAFHFEPPSTRVLVTAAQLIAAGAT-----E
Mvan_4975|M.vanbaalenii_PYR-1 GLPTAQRLVRCATAIRTADEAFHFEPPSTRVLVTAAHLIAAGAS-----E
MAV_2455|M.avium_104 PLATAQRLVRCAVAIRTADEAFHFEPPSTRVLVTAAQLIAAGAT-----E
TH_4050|M.thermoresistible__bu PLAVARRLVQCAVAIRTADAAFHFEPPSTRVLVTAGHLIAAGAG-----E
MSMEG_6809|M.smegmatis_MC2_155 DADTARALVSVGAAIRNIDGSPLREVASTRMLILAGGLVAEGLP-----L
. * . . . .. : *
MMAR_2286|M.marinum_M IIAASRALALVRGRDYVIPQDIIEVVPDVLRHRLVLTYDALADEISPEIV
MUL_1488|M.ulcerans_Agy99 IIAASRALALVRGRDYVIPQDIIEVVPDVLRHRLVLTYDALADEISPEIV
Mb1515|M.bovis_AF2122/97 IIAAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEISPEIV
Rv1479|M.tuberculosis_H37Rv IIAAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEISPEIV
MLBr_01810|M.leprae_Br4923 IIKASRSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYNALADEISPEIV
MAB_0653|M.abscessus_ATCC_1997 FCKAARALALLADRNHVLPDDIKALAHRILRHRLILGFEAVAENVTAEVL
Mflv_1772|M.gilvum_PYR-GCK LEAAEACVLAPLSSDGAIAEGLREVAAAGLAAAGNPSPNR----------
Mvan_4975|M.vanbaalenii_PYR-1 LEAAEACVLAPLSSDGGVSEGLREVAAASLADADSPNPNR----------
MAV_2455|M.avium_104 LDAADACILAPLSSDGAVTDGLREVAAASLATSNS-SP------------
TH_4050|M.thermoresistible__bu LDAAEACILAPLSSDGAVGDGLREVAVACLTGADSSS-------------
MSMEG_6809|M.smegmatis_MC2_155 RRAVRAAIVEALSDDHDIIRALGELVDAHLP-------------------
. .: . : : : : *
MMAR_2286|M.marinum_M INRVLQTVALPQVNAVPQQGHSVPPVMQAAAAAGGR
MUL_1488|M.ulcerans_Agy99 INRVLQTVALPQVNAVPQQGHSVPPVMQAAAAAGGR
Mb1515|M.bovis_AF2122/97 INRVLQTVALPQVNAVPQQGHSVPPVMQAAAAASGR
Rv1479|M.tuberculosis_H37Rv INRVLQTVALPQVNAVPQQGHSVPPVMQAAAAASGR
MLBr_01810|M.leprae_Br4923 INRVLQTVALPQVNSFPQQGHSVPSVTQAAAAASGR
MAB_0653|M.abscessus_ATCC_1997 IDNIIQAVRTP-------------------------
Mflv_1772|M.gilvum_PYR-GCK ------------------------------------
Mvan_4975|M.vanbaalenii_PYR-1 ------------------------------------
MAV_2455|M.avium_104 ------------------------------------
TH_4050|M.thermoresistible__bu ------------------------------------
MSMEG_6809|M.smegmatis_MC2_155 ------------------------------------