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AIESGFAHKNGAGGRLEGRRPYYTPVGNEDTVFKAAYRQGLSIVLKGPTGCGKTRFVEAMAHDLDRPLIT VACHDDLTTADLVGRYLLKGDETVWVDGPLTRAVREGAICYLDEVVEARQDTTVVLHPLADHRRQLPIER LGVTLDAAPGFGLVVSYNPGYQSVLKDLKDSTRQRMVAIEFGFPAPEVEVGIVAHEAGVDERTAAELVRF GQAIRRLETGGLREVASTRVLIAAARLIAEGLPVAVAAQVAVAGPLTDDIAVARGLNELIEVYLGETAAN D*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4155 | - | - | 100% (282) | ATPase |
| M. gilvum PYR-GCK | Mflv_2458 | - | 2e-97 | 65.28% (265) | ATPase |
| M. gilvum PYR-GCK | Mflv_1772 | - | 5e-65 | 51.42% (247) | ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2450c | - | 5e-07 | 23.91% (230) | hypothetical protein Mb2450c |
| M. tuberculosis H37Rv | Rv2426c | - | 5e-07 | 23.91% (230) | hypothetical protein Rv2426c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1619 | - | 5e-06 | 23.50% (217) | hypothetical protein MAB_1619 |
| M. marinum M | MMAR_3752 | - | 9e-08 | 24.78% (230) | hypothetical protein MMAR_3752 |
| M. avium 104 | MAV_1270 | - | 1e-126 | 81.88% (276) | putative denitrification regulatory protein nirQ |
| M. smegmatis MC2 155 | MSMEG_6809 | cbbQ | 7e-98 | 66.80% (259) | CbbQ protein |
| M. thermoresistible (build 8) | TH_4050 | - | 2e-65 | 51.42% (247) | PUTATIVE ATPase associated with various cellular activities, |
| M. ulcerans Agy99 | MUL_3695 | - | 2e-07 | 24.35% (230) | hypothetical protein MUL_3695 |
| M. vanbaalenii PYR-1 | Mvan_4196 | - | 1e-96 | 68.90% (254) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3752|M.marinum_M ----MSVPARS----------VPLFADIADVSRRLAQTGYLPDTATATAV
MUL_3695|M.ulcerans_Agy99 ----MSVPARS----------VPLFADIADVSRRLAQTGYLPDTATATAV
Mb2450c|M.bovis_AF2122/97 ----MTVPARP----------TPLFADIADVSRRLAETGYLPDTATATAV
Rv2426c|M.tuberculosis_H37Rv ----MTVPARP----------TPLFADIADVSRRLAETGYLPDTATATAV
MAB_1619|M.abscessus_ATCC_1997 ----MSDPLRPSGSSQSRTQTAPLFTSIDDVTTRLAETGYLADTATATAV
Mflv_4155|M.gilvum_PYR-GCK -MAIESG---------------FAHKNGAGGRLEGRRPYYTPVGNEDTVF
MAV_1270|M.avium_104 -MVDQSG---------------LAYVHAAEA-----RPYYRAVGSEEAVF
MSMEG_6809|M.smegmatis_MC2_155 --MSDAA---------------VVLENRS--------PFYVPVADEAEVF
Mvan_4196|M.vanbaalenii_PYR-1 MTVNNFR---------------LTTEAGSPA------PFYRAAGPEVEIF
TH_4050|M.thermoresistible__bu ----------------------LTAKT------------YFSNGDEVRLF
* . .
MMAR_3752|M.marinum_M FLADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARAL
MUL_3695|M.ulcerans_Agy99 FLADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARAL
Mb2450c|M.bovis_AF2122/97 FLADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARAL
Rv2426c|M.tuberculosis_H37Rv FLADRLGKPLLVEGPAGVGKTELARAVAQATGSGLVRLQCYEGVDEARAL
MAB_1619|M.abscessus_ATCC_1997 FLADRLGKPLLVEGPAGVGKTELARAVAHTTGSGLVRLQCYEGVDEARAL
Mflv_4155|M.gilvum_PYR-GCK KAAYRQGLSIVLKGPTGCGKTRFVEAMAHDLDRPLITVACHDDLTTADLV
MAV_1270|M.avium_104 KAAYRQGLALVLKGPTGCGKTRFVEAMAYDLGRPLITVACHDDLTTADLV
MSMEG_6809|M.smegmatis_MC2_155 RAAARRGTPVLLKGPTGCGKTRFVESMAHELGRDLITVAGHEDMTSADLV
Mvan_4196|M.vanbaalenii_PYR-1 RAAARRGSPVLLKGPTGCGKTRFVEAMAHDLGRELITVAGHEDMTSADLV
TH_4050|M.thermoresistible__bu EQAYRQRLPVMLTGPTGCGKTRLIEHMGALLGRPVVTISCHDDLTSADLV
* * .::: **:* ***.: . :. . :: : ::.: * :
MMAR_3752|M.marinum_M YEWNHAKQILRIQSGSGDWEATKDDVFSEEFLLQRPLLTAIRRTEPTVLL
MUL_3695|M.ulcerans_Agy99 YEWNHAKQILRIQSGSGDWEATKDDVFSEEFLLQRPLLTAIRRTEPTVLL
Mb2450c|M.bovis_AF2122/97 YEWNHAKQILRIQAGSGDWEATKTDVLSEEFLLQRPLLTAIRRTEPTVLL
Rv2426c|M.tuberculosis_H37Rv YEWNHAKQILRIQAGSGDWEATKTDVFSEEFLLQRPLLTAIRRTEPTVLL
MAB_1619|M.abscessus_ATCC_1997 YEWNHAKQILRIQAGSGDWDETKTDVFAEEFLLSRPLLTAIRREDPTVLL
Mflv_4155|M.gilvum_PYR-GCK GRYLLKGDETVWVDGPLTRAVREGAICYLDEVVEARQDTTVVLHP----L
MAV_1270|M.avium_104 GRYLLRGDETVWVDGPLTRAVREGAICYLDEVVEARQDTTVVLHP----L
MSMEG_6809|M.smegmatis_MC2_155 GRFLLKGGETIWVDGPLTRAVRTGAICYLDEIVEARQDTTVVIHP----L
Mvan_4196|M.vanbaalenii_PYR-1 GRFLLKGGETVWVDGPLTRAVREGAICYLDEIVEARQDTTVVIHP----L
TH_4050|M.thermoresistible__bu GRFMVTGGDVVWTDGPLTRAVKEGAICYLDEVVEARHDSLAVLHS----L
.: *. : : ::. : *
MMAR_3752|M.marinum_M IDETDKADIEIEGLLLEVLSDFAVTVPELGTLTAARAPFVLLTSNATREL
MUL_3695|M.ulcerans_Agy99 IDETDKADIEIEGLLLEVLSDFAVTVPELGTLTATRAPFVLLTSNATREL
Mb2450c|M.bovis_AF2122/97 IDETDKADIEIEGLLLEVLSDFAVTVPELGTLTATRAPFVLLTSNATREL
Rv2426c|M.tuberculosis_H37Rv IDETDKADIEIEGLLLEVLSDFAVTVPELGTLTATRAPFVLLTSNATREL
MAB_1619|M.abscessus_ATCC_1997 IDETDKADIEIEGLLLEVLSDFAVTIPELGTIAASRKPFVLLTSNATREL
Mflv_4155|M.gilvum_PYR-GCK ADHRRQLPIERLGVTLDAAPGFGLVVSYNPGYQS-----------VLKDL
MAV_1270|M.avium_104 ADHRRQLPIERLGITLDAAPGFGLVVSYNPGYQS-----------VLKDL
MSMEG_6809|M.smegmatis_MC2_155 ADHRRELPIDRLGTTLSAVPGFQLVISYNPGYQS-----------VLKSI
Mvan_4196|M.vanbaalenii_PYR-1 ADHRRELPIDRLGTTLSAAPGFQLVISYNPGYQS-----------ILKSL
TH_4050|M.thermoresistible__bu TDHRRTLYLDRAGEVVAAPENFMLVCSYNPAYRS-----------SLKDL
*. :: * : . .* :. . : :.:
MMAR_3752|M.marinum_M SEALKRRCLFLHIDFPTPEMERRILLSRVPELPEHIAEELVRIIGVLRGM
MUL_3695|M.ulcerans_Agy99 SEALKRRCLFLHIDFPTPEMERRILLSRVPELPEHIAEELVRIIGVLRGM
Mb2450c|M.bovis_AF2122/97 SEALKRRCLYLHIDFPTPELERRILLSRVPELPEHFAEELVRIIGVLRGM
Rv2426c|M.tuberculosis_H37Rv SEALKRRCLYLHIDFPTPELERRILLSRVPELPEHFAEELVRIIGVLRGM
MAB_1619|M.abscessus_ATCC_1997 SEALKRRCLFLHIDFPDAELERRILLKRVPELPASLAEELVRIIGVLRNM
Mflv_4155|M.gilvum_PYR-GCK KDSTRQRMVAIEFGFPAPEVEVGIVAHEA-GVDERTAAELVRFGQAIRRL
MAV_1270|M.avium_104 KDSTRQRMVAIEFDFPAADVEEGIVAHEA-GVDAATAAELVRFGQAIRRL
MSMEG_6809|M.smegmatis_MC2_155 KESTRQRFIAIELDFPPPHVETEIVAHEA-GVDADTARALVSVGAAIRNI
Mvan_4196|M.vanbaalenii_PYR-1 KDSTRQRFVAISLDFPAAEIETEVVAQEA-GIDESTAGSLVALGNAIRNL
TH_4050|M.thermoresistible__bu KPSFRQRFVTLPMSYLPPEREAEVIVAET-GVPLAVARRLVQCAVAIRTA
. : ::* : : :.: .. * :: .. : * ** .:*
MMAR_3752|M.marinum_M QLKKLPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQQRATG
MUL_3695|M.ulcerans_Agy99 QLKKLPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQQRATG
Mb2450c|M.bovis_AF2122/97 QLKKVPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQQRATG
Rv2426c|M.tuberculosis_H37Rv QLKKVPSIAETIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQQRATG
MAB_1619|M.abscessus_ATCC_1997 QLKKVPSVAETIDWGRTILALGLDTLDDAVIASTLGVVLKHHSDQQRAAG
Mflv_4155|M.gilvum_PYR-GCK ETGGLREVASTRVLIAAARLIAEGLPVAVAAQVAVAGPLTDDIAVARGLN
MAV_1270|M.avium_104 ETAGLREVASTRVLIAAGRLIAEGLSLPEAARAAIAGPLTDDVAVGKALG
MSMEG_6809|M.smegmatis_MC2_155 DGSPLREVASTRMLILAGGLVAEGLPLRRAVRAAIVEALSDDHDIIRALG
Mvan_4196|M.vanbaalenii_PYR-1 DGAALSEVASTRMLILAGGLVAEGLHLLDAVQSAVVEVLSDDPDVIRGLG
TH_4050|M.thermoresistible__bu DAAFHFEPPSTRVLVTAGHLIAAGAGELDAAEACILAPLSSDGAVGDGLR
: . ..* : :. . . : *. . .
MMAR_3752|M.marinum_M ELRLN------------
MUL_3695|M.ulcerans_Agy99 ELRLN------------
Mb2450c|M.bovis_AF2122/97 ELRLN------------
Rv2426c|M.tuberculosis_H37Rv ELRLN------------
MAB_1619|M.abscessus_ATCC_1997 ELRLN------------
Mflv_4155|M.gilvum_PYR-GCK ELIEVYLG---ETAAND
MAV_1270|M.avium_104 EMIGIYFGSGGSLGSAD
MSMEG_6809|M.smegmatis_MC2_155 ELVDAHLP---------
Mvan_4196|M.vanbaalenii_PYR-1 ELVDAVLPRR-------
TH_4050|M.thermoresistible__bu EVAVACLTGADSSS---
*: