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VTLTNAPDDASTRETVTPQARTALWASLVGTTIEWYDFFLYATAASLVFNQAFFPDQSTFVGTMLSFATF AVGFVVRPIGGFVFGHVGDRIGRKKTLALTMLLMGGATALMGVLPTAAQIGILAPILLLLLRIVQGFALG GEWAGAVLLAVEHGPARRRGLFGSIPQVGLALGLALGTGVFALLQIALPDEAFLTYGWRIAFLFSIVLVV FGVVVRLKASETPSFEKVRDSDDRAAVPLREVFRPPVLKSTVLGMLSRWGEGAAFNTWGVFAIAYATGTL GLAKVPVLLVVTAAALLMAALLPVSGLLADRYGPKRIYATGIALYAAAVFPVFALFGTEDIALYALGMIL VFGIVHALFYGAQGTLYASLFPARIRYTGLSTVYQLSGVYASGLTPLILTALIGAAGGSPWIACGYLVAT AVISVVATLALKPAPLHTL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0140 | - | - | 100% (439) | major facilitator transporter |
| M. gilvum PYR-GCK | Mflv_2383 | - | 1e-91 | 44.08% (422) | major facilitator transporter |
| M. gilvum PYR-GCK | Mflv_1471 | - | 4e-82 | 41.37% (423) | general substrate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1232 | - | 2e-62 | 35.61% (424) | integral membrane transport protein |
| M. tuberculosis H37Rv | Rv1200 | - | 2e-62 | 35.61% (424) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2481 | - | 4e-88 | 43.24% (407) | putative integral membrane transporter |
| M. marinum M | MMAR_4238 | - | 9e-66 | 35.45% (426) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 1e-168 | 67.70% (418) | major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_5051 | - | 0.0 | 80.19% (429) | major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_2446 | - | 0.0 | 85.14% (444) | PUTATIVE major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_0949 | - | 3e-65 | 35.21% (426) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_5300 | - | 7e-82 | 41.05% (419) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0140|M.gilvum_PYR-GCK ---------------MTLTNAPDDASTRET----VTPQARTALWASLVGT
TH_2446|M.thermoresistible__bu VQPYAHPPGSALLNAVTLLDAPVAPHHDDDSA--VTPQARTALWASLVGT
MSMEG_5051|M.smegmatis_MC2_155 ---------------MTVTADLVDEQPNTPD---EKKTVRTAVLASVVGT
MAV_4627|M.avium_104 ---------MAATLPAPAPAGLADGHPLDESAEQQRRRLRIVVAASLLGT
MAB_2481|M.abscessus_ATCC_1997 ---------------MTTTSAVPAVHAGGPADG-DAPAARTVALSCMVGT
Mvan_5300|M.vanbaalenii_PYR-1 ------------------MSTQHDARPDGPPS--ITTGLKRVVVASMAGT
Mb1232|M.bovis_AF2122/97 --------------------------------------MKRVALACLVGS
Rv1200|M.tuberculosis_H37Rv --------------------------------------MKRVALACLVGS
MMAR_4238|M.marinum_M --------------------------------------MSRVALACVVGS
MUL_0949|M.ulcerans_Agy99 --------------------------------------MSRVALACVVGS
. :.: *:
Mflv_0140|M.gilvum_PYR-GCK TIEWYDFFLYATAASLVFNQAFFPD-QSTFVGTMLSFATFAVGFVVRPIG
TH_2446|M.thermoresistible__bu TIEWYDFFLYATAAGLVFNHAFFPD-QSTFVGTMLSFATFAVGFVVRPIG
MSMEG_5051|M.smegmatis_MC2_155 TIEWYDFFLYATAASLVFNHAFFPD-QSSFVGTMLAFATFAVGFVVRPIG
MAV_4627|M.avium_104 TVEWYDFFLYATAAGLVFNKVFFPN-ESSLVGTLLAFATFAVGFVMRPIG
MAB_2481|M.abscessus_ATCC_1997 TIEWYDFYLYATAAALVLKPLFFPS-VSPTAGTLASFATYAAGFGARPVG
Mvan_5300|M.vanbaalenii_PYR-1 VVEWYEFFLYATAATLVFNKVFFAEGTSEAAGLIAALLTYAVGFVARPLG
Mb1232|M.bovis_AF2122/97 AIEFYDFLIYGTAAALVFPTVFFPH-LDPTVAAVASMGTFAVAFLSRPFG
Rv1200|M.tuberculosis_H37Rv AIEFYDFLIYGTAAALVFPTVFFPH-LDPTVAAVASMGTFAVAFLSRPFG
MMAR_4238|M.marinum_M TVEYYDFCIYGTAAALVFPAVFYPG-LSPALATIASMGTFATAFLSRPLG
MUL_0949|M.ulcerans_Agy99 TVEYYDFCIYGTAAALVFPAVFYPG-LSPALATIASMGTFATAFLSRPLG
.:*:*:* :*.*** **: *:. . . : :: *:*..* **.*
Mflv_0140|M.gilvum_PYR-GCK GFVFGHVGDRIGRKKTLALTMLLMGGATALMGVLPTAAQIGILAPILLLL
TH_2446|M.thermoresistible__bu GVVFGHVGDRIGRKRTLALTMVLMGGATALMGVLPTAAQIGALAPILLLL
MSMEG_5051|M.smegmatis_MC2_155 GFVFGHVGDRIGRKKTLALTMLLMGVATALMGFLPTAAQIGVLAPILLLV
MAV_4627|M.avium_104 GLVFGHIGDRIGRKRSLALTMLIMGGATALIGVLPTAAQIGAWAPVLLLV
MAB_2481|M.abscessus_ATCC_1997 AVIAGHLGDRVGRKAVLVGALLLMGVATAVIGALPTYSEAGVLAPAALAT
Mvan_5300|M.vanbaalenii_PYR-1 GVVFGHFGDKYGRKKLLQFAILLVGAVTFLMGCLPTYAQIGVWAPILLVV
Mb1232|M.bovis_AF2122/97 AAVFGYFGDRLGRKKTLVATLLIMGLATVTVGLVPTTVAIGAAAPLILTT
Rv1200|M.tuberculosis_H37Rv AAVFGYFGDRLGRKKTLVATLLIMGLATVTVGLVPTTVAIGAAAPLILTT
MMAR_4238|M.marinum_M AAVFGHFGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIGVSAPLILVA
MUL_0949|M.ulcerans_Agy99 AAVFGHFGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIGVSAPLILVA
. : *:.**: *** * :::::. * :* :*: * ** *
Mflv_0140|M.gilvum_PYR-GCK LRIVQGFALGGEWAGAVLLAVEHGPARRRGLFGSIPQVGLALGLALGTGV
TH_2446|M.thermoresistible__bu LRIVQGFALGGEWAGAVLLAVEHGPPRRRGLCGSIPQIGLALGLALGTGV
MSMEG_5051|M.smegmatis_MC2_155 LRIVQGFALGGEWAGAVLLAVEHSPRNRRGLFGSIPQVGLALGLALGTAV
MAV_4627|M.avium_104 LRVLQGFALGGEWGGAVLLAVEHSPGDRRGRYGAVPQVGLALGLALGTGI
MAB_2481|M.abscessus_ATCC_1997 LRVLQGLAAGAEWGGAALLAVEHAPVGRRGLFGSFTQLGSPAGMLLATGV
Mvan_5300|M.vanbaalenii_PYR-1 LRFMQGFAVGGEWGGAVLLVAEHSPNKERGFWASWPQAAVPVGNMLATVV
Mb1232|M.bovis_AF2122/97 MRLLQGFAVGGEWAGSALLSAEYAPASKRGWYGMFTVVGGGIALVLTSLT
Rv1200|M.tuberculosis_H37Rv MRLLQGFAVGGEWAGSALLSAEYAPASKRGWYGMFTVVGGGIALVLTSLT
MMAR_4238|M.marinum_M LRLLQGFAVGGEWAGSALLSIESAPAHKRGYYGMFTVLGGGVALVVSGLT
MUL_0949|M.ulcerans_Agy99 LRLLQGFAVGGEWAGSALLSIESAPAHKRGYYGMFTVLGGGVALVVSGLT
:*.:**:* *.**.*:.** * .* .** . . . . :
Mflv_0140|M.gilvum_PYR-GCK FALLQIALP--DEAFLTYGWRIAFLFSIVLVVFGVVVRLKASETPSFEKV
TH_2446|M.thermoresistible__bu FALLQIALP--DDAFLTYGWRIAFLLSIVLVVFGVVVRLRATETPAFQRV
MSMEG_5051|M.smegmatis_MC2_155 FVVLQVALT--PEAFLSYGWRIAFLVSIVLVIFGVVVRFRVAETPAFEQV
MAV_4627|M.avium_104 FAFLQIVLG--PARFLSYGWRIGFLLSVLLVAIGIVVRLRVEETPAFREL
MAB_2481|M.abscessus_ATCC_1997 FGLTRALTG--PEAFLAFGWRIPFLSSIVLVVVGLAIRLRLRDSVVFRKV
Mvan_5300|M.vanbaalenii_PYR-1 LLVLTGTLS--NDAFLSWGWRVAFWLSAVVVLVGYYIRTKVTDAPIFVAA
Mb1232|M.bovis_AF2122/97 FLGVNYTIGESSPTFMQWGWRIPFLVSAALIAVALYVRFNIDETPVFAR-
Rv1200|M.tuberculosis_H37Rv FLGVNYTIGESSPTFMQWGWRIPFLVSAALIAVALYVRFNIDETPVFAR-
MMAR_4238|M.marinum_M FLGVNYTIGESSSAFLQWGWRVPFLLSALLIAFALYVRLEINETPVFARA
MUL_0949|M.ulcerans_Agy99 FLGVNYTIGESSSALLQWGWRVPFLLSALLIAFALYVRLEINETPVFARA
: :: :***: * * :: .. :* . :: *
Mflv_0140|M.gilvum_PYR-GCK RDSDD---RAAVP---LREVFRPP-VLKSTVLGMLSRWGEGAAFNTWGVF
TH_2446|M.thermoresistible__bu RDTGD---RAAVP---LRDVFRPP-VLRSTLLGLLSRWGEGAAFNTWGVF
MSMEG_5051|M.smegmatis_MC2_155 QREND---RAAVP---VRDVFRPP-VLRSTILGLLSRWGEGAAFNTWGVF
MAV_4627|M.avium_104 QDLQA---ASTVP---IRDILRERRSRRNTVLGLLSRWAEGSAFNTWGVF
MAB_2481|M.abscessus_ATCC_1997 LERGE---AARLP---VVEVLRTQ--SRNVLLTTGLRLSQIALFVLLTTF
Mvan_5300|M.vanbaalenii_PYR-1 QEEVE---RVKSVSYGVVEVLKRY--PRGVFTAMGLRFAENIMYYLVVTF
Mb1232|M.bovis_AF2122/97 -ERADEKTRLGPAETPIAQVLRRQ--RREIVLAAGSAVCCFGFVYLASTY
Rv1200|M.tuberculosis_H37Rv -ERADEKTRLGPAETPIAQVLRRQ--RREIVLAAGSAVCCFGFVYLASTY
MMAR_4238|M.marinum_M MAQADDQESTAAARAPLAAVLCRQ--RREIVLAAGAMLAAFGCLYLASTF
MUL_0949|M.ulcerans_Agy99 MAQADDQESTAAARAPLAAVLCRQ--RREIVLAAGAMLAAFGCLYLASTF
: :: : . .:
Mflv_0140|M.gilvum_PYR-GCK AIAYATGTLGLAKVPVLLVVTAAALLMAALLPVSGLLADRYGPKRIYATG
TH_2446|M.thermoresistible__bu AIAYATTTLGLAKVPVLVAVTAAALLMAVLLPVSGVLTDRFGAKRIYTIG
MSMEG_5051|M.smegmatis_MC2_155 TIAYATTTLGLDKVAVLIVVTVAALLMAVLLPVSGALADRFSPRTVYAAG
MAV_4627|M.avium_104 AISYATGALGLNRVSVLIAVTIAALLMAVLLPVSGVLTDRFGARRVYLAG
MAB_2481|M.abscessus_ATCC_1997 SLTYLQGSFGGDSQIGLTAVLISSALGILSTPVWSALSDRVGRRPLYLFG
Mvan_5300|M.vanbaalenii_PYR-1 SIVYLKTHVGADTSDILWWLLAAHAVHFLVVPQVGRLADRFGRRPVYIAG
Mb1232|M.bovis_AF2122/97 LASYAQTRLGYSRGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAG
Rv1200|M.tuberculosis_H37Rv LASYAQTRLGYSRGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAG
MMAR_4238|M.marinum_M LPSYAQLHLGYSRNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVG
MUL_0949|M.ulcerans_Agy99 LPSYAQLHLGYSRNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVG
* .* * . : . . * *: . : : *
Mflv_0140|M.gilvum_PYR-GCK IALYAAAVFPVFALFGTEDIALYALGMILVFGIVHALFYGAQGTLYASLF
TH_2446|M.thermoresistible__bu ITAYALAVFPVFALFGTGEIVFYTLGMLLVFGVIHALFYGAQGTLYASLF
MSMEG_5051|M.smegmatis_MC2_155 IAAYGVIVFPAFALFNTGSIAAYAVGMILAFGVIHALFYGAQGTLYASLF
MAV_4627|M.avium_104 IACYGLAAFPAFALFGTKKLLWFGLAMVIVFGVVHALFYGAQGTLYSALY
MAB_2481|M.abscessus_ATCC_1997 SAAGPLALGLFFLAAGSGSKVLVVLSIVFGINVVHDAMYGPQAAWFAELF
Mvan_5300|M.vanbaalenii_PYR-1 AMLAATWGFFAFPMMNSGDYLLILGAVILGL-MIHALMYAPQPAIMAEMF
Mb1232|M.bovis_AF2122/97 WAVALPWSLLVMPLIDSGSPSLFAV-AVVGMYAIGGFGFGPTASFIPELF
Rv1200|M.tuberculosis_H37Rv WAVALPWSLLVMPLIDSGSPSLFAV-AVVGMYAIGGFGFGPTASFIPELF
MMAR_4238|M.marinum_M WAVGLFWSPLVMPLIGSGDTVGFTV-ALLGLYAVAASGFGPAASLIPELF
MUL_0949|M.ulcerans_Agy99 WAVGLFWSPLVMPLIGSGDTVGFTV-ALLGLYAVAASGFGPAASLIPELF
: .: . :. : : :.. : . ::
Mflv_0140|M.gilvum_PYR-GCK PARIRYTGLSTVYQLSGVYASGLTPLILTALIGAAGGSPWIACGYLVATA
TH_2446|M.thermoresistible__bu PARIRYTGLSTVYQLSGIFASGVTPMILTALIAAAGGAPWLACGYLVATA
MSMEG_5051|M.smegmatis_MC2_155 PTRSRYTGLSTVYQLSGVYASGLTPLILTSLIAAGGGKPWYACGYLVATA
MAV_4627|M.avium_104 PTNTRYTGLSFVYQFSGVYASGVTPMILTALIAALGGAPWLACGYLVATA
MAB_2481|M.abscessus_ATCC_1997 DTRVRYSGASLGYQIGAVLSGGFAPLIAAALLAANHGDPRLIVCYYLALS
Mvan_5300|M.vanbaalenii_PYR-1 PTRMRYSGVSLGYQVTSIVAGSLAPAIATWLLDR-FGTWVPIAVYLAGAA
Mb1232|M.bovis_AF2122/97 ATSYRYTGSALAANLAGVAGGALPPVIAGALVATYGSWA--IGVMLAILA
Rv1200|M.tuberculosis_H37Rv ATSYRYTGSALAANLAGVAGGALPPVIAGALVATYGSWA--IGVMLAILA
MMAR_4238|M.marinum_M ATRYRYTGTALALNVAGIVGGAAPPLIAGTLLASYGSSA--VGLMMTALV
MUL_0949|M.ulcerans_Agy99 ATRYRYTGTALALNVAGIVGGAAPPLIAGTLLASYGSSA--VGLMMTALV
: **:* : :. .: ... .* * *: .
Mflv_0140|M.gilvum_PYR-GCK VISVVATLALKPA---PLHTL--------------
TH_2446|M.thermoresistible__bu LISVVATTALRPA---PLHRL--------------
MSMEG_5051|M.smegmatis_MC2_155 VISVVATLLLRPE---H------------------
MAV_4627|M.avium_104 VISVLATALIRDR---DLYL---------------
MAB_2481|M.abscessus_ATCC_1997 VLTFGAACVARET---YRDQIGDSL----------
Mvan_5300|M.vanbaalenii_PYR-1 VITLVAAWFTRETNGIDLHSLDVADREQLAKAGIV
Mb1232|M.bovis_AF2122/97 LISLVCTYRLPETAGSALVSR--------------
Rv1200|M.tuberculosis_H37Rv LISLVCTYRLPETAGSALVSR--------------
MMAR_4238|M.marinum_M AASLLCTYLLPETAGAPLTAA--------------
MUL_0949|M.ulcerans_Agy99 AASLLCTYLLPETAGAPLTAA--------------
:. .: