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M. gilvum PYR-GCK Mflv_1881 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 1958774 - 1959934
length: 386

SGFIETEEQQALRSAVAAMVAGYGQDYYLEKSRAGEHTDELWSEAGKLGFIGVNLPEEYGGGGAGMYELS
LVMEEMAAGGASLLMMVVSPAINGTIIAKFGTEEQKKRWLPGIADGTLTMAFAITEPDAGSNSHRITTTA
RRDGSDWILSGQKVYISGVDQAQAVLIVGRTEDHKTGNLKPALFVVPTDTPGLTYTKIPMEIVSPEFQFQ
VFLDEVRLPADALVGSEDAAIAQLFAGLNPERIMGAASAVGMGRFALAKAVEYVKGRQVWKTPIGAHQGL
SHPLAQNHIEVELAKLMMQKAAALYDAGADEAAAEAANMAKYAAGEASVRAVDQAVQSLGGNGLTKEYGV
AAMLTASRLARIAPVSREMILNFVAQTSLGLPRSY*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_1881 - - 100% (386) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_4615 - e-129 59.84% (381) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_2442 - 2e-68 38.52% (392) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0997c fadE12 0.0 82.60% (385) acyl-CoA dehydrogenase FADE12
M. tuberculosis H37Rv Rv0972c fadE12 0.0 82.86% (385) acyl-CoA dehydrogenase FADE12
M. leprae Br4923 MLBr_00737 fadE25 1e-34 28.06% (360) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_1070c - 1e-160 72.06% (383) acyl-CoA dehydrogenase
M. marinum M MMAR_4535 fadE12 0.0 83.38% (385) acyl-CoA dehydrogenase FadE12
M. avium 104 MAV_1088 - 0.0 83.38% (385) acyl-CoA dehydrogenase fadE12
M. smegmatis MC2 155 MSMEG_5494 - 0.0 88.60% (386) acyl-CoA dehydrogenase fadE12
M. thermoresistible (build 8) TH_3553 - 0.0 83.29% (389) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_4707 fadE12 0.0 83.12% (385) acyl-CoA dehydrogenase FadE12
M. vanbaalenii PYR-1 Mvan_4850 - 0.0 92.69% (383) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0997c|M.bovis_AF2122/97           -------MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSE
Rv0972c|M.tuberculosis_H37Rv        -------MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSE
MMAR_4535|M.marinum_M               -------MTDTSFIENEDRRALRKAVSEWASNYGHEYYLKKARAHEHTTE
MUL_4707|M.ulcerans_Agy99           ------MMTGTSFIENEDRRALRKAVSEWASNYGHEYYLKKARAHEHTTE
MAV_1088|M.avium_104                -------MTDSSFIENEERQALRKAVAEWASNYGSEYYLRKARAHEHTNE
Mflv_1881|M.gilvum_PYR-GCK          ---------MSGFIETEEQQALRSAVAAMVAGYGQDYYLEKSRAGEHTDE
Mvan_4850|M.vanbaalenii_PYR-1       ---------MS-FIETDEQQALRKAVAAMAANYGQDYYLEKARAGQHTDE
MSMEG_5494|M.smegmatis_MC2_155      ---------MSGFVETEEQQALRRAVAAMAANYGQDYYLEKARAGQHTTE
TH_3553|M.thermoresistible__bu      ---------VTGFVESEEQRALRRAAAELAAGYGQDYYLEKARAGEHTDE
MAB_1070c|M.abscessus_ATCC_199      ------MTQPNPYVESDERKALRQAVASLAASYGHEYYLEKSKTHEPLAE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                                :   :::. ** :    .      :     :  .   *

Mb0997c|M.bovis_AF2122/97           LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
Rv0972c|M.tuberculosis_H37Rv        LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
MMAR_4535|M.marinum_M               LWSEAGKLGFIGVNLPEEYGGGGAGMYELSMVMEEMAAAGSALLLMVVSP
MUL_4707|M.ulcerans_Agy99           LWSEAGKLGFIGVNLPEEYGGGGAGMYELSMVMEEMAAAGSALLLMVVSP
MAV_1088|M.avium_104                LWSEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAAAGSALLLMVVSP
Mflv_1881|M.gilvum_PYR-GCK          LWSEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAAGGASLLMMVVSP
Mvan_4850|M.vanbaalenii_PYR-1       LWSEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAAAGSSLLMMVVSP
MSMEG_5494|M.smegmatis_MC2_155      LWNEAGKLGFIGVNLPEEYGGGGAGMYELSLVMEEMAATGCALLMMVVSP
TH_3553|M.thermoresistible__bu      LWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEELSAAGCGLLMMVVSP
MAB_1070c|M.abscessus_ATCC_199      LWDEAGKLGFLGVNIPEEYGGGGAGMYELGLVFEELSAAGCPLLLMVVSP
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
                                         .  ** .:::****** **.     :*:**::  ..   :: .  

Mb0997c|M.bovis_AF2122/97           AINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTA
Rv0972c|M.tuberculosis_H37Rv        AINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTA
MMAR_4535|M.marinum_M               AINGTIISKFGTDEQKQRWLPGIADGTLTMAFAITEPDAGSNSHKITTTA
MUL_4707|M.ulcerans_Agy99           AINGTIISKFGTDEQKQRWLPGIADGTLTMAFAITEPEAGSNSHKITTTA
MAV_1088|M.avium_104                AINGTIISKFGTEEQKKRWLPGIADGTLTMAFAITEPDAGSNSHKITTTA
Mflv_1881|M.gilvum_PYR-GCK          AINGTIIAKFGTEEQKKRWLPGIADGTLTMAFAITEPDAGSNSHRITTTA
Mvan_4850|M.vanbaalenii_PYR-1       AINGTIISKFGTEEQKKRWIPGIADGSLTMAFAITEPDAGSNSHKITTTA
MSMEG_5494|M.smegmatis_MC2_155      AINGTIISKFGTEEQKRRWLPGIADGSITMAFAITEPDAGSNSHRITTTA
TH_3553|M.thermoresistible__bu      AINGTIISRFGTEDQKRRWLPGIADGSITMAFAITEPDAGSNSHRITTTA
MAB_1070c|M.abscessus_ATCC_199      AINATIIARYGTDAQKKSWLPAMAEGSFKMAFAITEPDAGSNSHNIITTA
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
                                     :.   :   *::  *:  :*.:*      ::*::* :***::  : * *

Mb0997c|M.bovis_AF2122/97           RRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTG---KLRPALFVVP
Rv0972c|M.tuberculosis_H37Rv        RRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTG---KLRPALFVVP
MMAR_4535|M.marinum_M               RRDGSDWIIKGQKVYISGIDQAQAVLVVGRTEEAKTG---KLRPALFVVP
MUL_4707|M.ulcerans_Agy99           RRDGSDWIIKGQKVYISGIDQAQAVLVVGRTEEAKTG---KLRPALFVVP
MAV_1088|M.avium_104                RRDGSDWILKGQKVFISGIDQAQAVLVVARTEEAKTG---KLRPALFVVP
Mflv_1881|M.gilvum_PYR-GCK          RRDGSDWILSGQKVYISGVDQAQAVLIVGRTEDHKTG---NLKPALFVVP
Mvan_4850|M.vanbaalenii_PYR-1       RRDGSDWVLSGQKVYISGVDQAQAVLVVGRTEDHKTG---SLKPALFVVP
MSMEG_5494|M.smegmatis_MC2_155      RRDGSDWILKGQKVFISGIDQAQAVLVVGRTEDHKTG---NLKPALFVIP
TH_3553|M.thermoresistible__bu      RRDGGDWILSGQKVFISGVDQAQAVLVVGRVQKDGTGRTKSLKPALFVVP
MAB_1070c|M.abscessus_ATCC_199      KRDGGDWILNGRKVFISGVNEANAVLVVARTEEAKTG---KLKPALFVVP
MLBr_00737|M.leprae_Br4923          KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGAN----GISAFIVH
                                    : **.**::.* * :*:. .::    ::.  :    .       : *:: 

Mb0997c|M.bovis_AF2122/97           TDAPGFSYTPIEMEL-VSPERQFQVFLDDVRLPADALVGAEDAAIAHLFA
Rv0972c|M.tuberculosis_H37Rv        TDAPGFSYTPIEMEL-VSPERQFQVFLDDVRLPADALVGAEDAAIAQLFA
MMAR_4535|M.marinum_M               TDTPGFTYTAIDMEL-VSPERQFQVFLDDVRLPADALVGAQDAAIAQLFA
MUL_4707|M.ulcerans_Agy99           TDTPGFTYTAIDMEL-VSPERQFQVFLDDVRLPADALVGAQDAAIAQLFA
MAV_1088|M.avium_104                TDAPGFSATPIEMEL-ISPERQFQVFLDDVRLPSDALVGAEDAAIAQLFA
Mflv_1881|M.gilvum_PYR-GCK          TDTPGLTYTKIPMEI-VSPEFQFQVFLDEVRLPADALVGSEDAAIAQLFA
Mvan_4850|M.vanbaalenii_PYR-1       TDTPGFTYTKIPMEI-VSPEFQFQVFLDEVRLPADALVGSEDAAIAQLFA
MSMEG_5494|M.smegmatis_MC2_155      TDTPGLHWTKIEMEL-ISPESQFQVFLDDVRVPADALVGSEDAALAQLFA
TH_3553|M.thermoresistible__bu      TDAPGLSYTKIEMEL-ISPESQFQVFLDDVRLPADALVGDEDAALAQLFA
MAB_1070c|M.abscessus_ATCC_199      TNTKGFEYTPIDMQL-TLPEQQFQVFLDDVRVPGDALVGSEDAALMQLFA
MLBr_00737|M.leprae_Br4923          KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALA
                                    .:  *:       ::    .   ::::*. *:*.* ::*  .:.:   :*

Mb0997c|M.bovis_AF2122/97           GLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQ
Rv0972c|M.tuberculosis_H37Rv        GLNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQ
MMAR_4535|M.marinum_M               GLNPERIMGAASAVGMGRFALNRAVDYVKTRQVWSTPIGAHQGLAHPLAQ
MUL_4707|M.ulcerans_Agy99           GLNPERIMGAASAVGMGRFALNRAVDYVKTRQVWSTPIGAHQGLAHPLAQ
MAV_1088|M.avium_104                GLNPERIMGAASSVGMGRFALARAAEYVKTRQVWGTPVGAHQGLSHPLAQ
Mflv_1881|M.gilvum_PYR-GCK          GLNPERIMGAASAVGMGRFALAKAVEYVKGRQVWKTPIGAHQGLSHPLAQ
Mvan_4850|M.vanbaalenii_PYR-1       GLNPERIMGAASAVGMGRFAIGRAVEYVKTRQVWKTPIGAHQGLSHPLAQ
MSMEG_5494|M.smegmatis_MC2_155      GLNPERIMGAASAVGMGRFAIHKAVDYVKTRQVWKVPIGSHQGLSHPLAQ
TH_3553|M.thermoresistible__bu      GLNPERIMGAASAIGMGRFAIGRAVDYVKNRQVWRTPIGAHQGLAHPLAQ
MAB_1070c|M.abscessus_ATCC_199      GLNPERIMGAASGVGLTRLALNKATEYVKTRQVWKTPIGAHQAIAHPLAE
MLBr_00737|M.leprae_Br4923          TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLAD
                                     *:  *   .*..:*: : *:  *  *.* *: :  .:.:.*.: . **:

Mb0997c|M.bovis_AF2122/97           CHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAV
Rv0972c|M.tuberculosis_H37Rv        CHIEVELAKLMTQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAV
MMAR_4535|M.marinum_M               CHIEVELAKLMMQKAATLYDHGDDGGAAEAANMAKYAAAEASARSVDQAV
MUL_4707|M.ulcerans_Agy99           CHIEVELAKLMMQKAATLYDHGDDGGAAEAANMAKYAAAEASARSVDQAV
MAV_1088|M.avium_104                CHIEVELAKLMMQKAATLYDAGNDMGAAEAANMAKYAAAEAATRSVDQAV
Mflv_1881|M.gilvum_PYR-GCK          NHIEVELAKLMMQKAAALYDAGADEAAAEAANMAKYAAGEASVRAVDQAV
Mvan_4850|M.vanbaalenii_PYR-1       NHIEVELAKLMMQKAASLYDAGDDAGAAEAANMAKYAAGEASVRAVDQAV
MSMEG_5494|M.smegmatis_MC2_155      NHIEIELAKLMMQKAAALYDAGDDLGAAEAANMAKYAAGEASVRAVDQAV
TH_3553|M.thermoresistible__bu      NHIEIELAKLMMQKAAALYDLGDGAGAAEAANMAKYAAGEASARAVDQAV
MAB_1070c|M.abscessus_ATCC_199      IKVELELAKLMMQKAATLYDCGDDWGAAEAANMAKYAAADVACRAADRAV
MLBr_00737|M.leprae_Br4923          MAMKVEAARLIVYAAAARAERGEP-DLGFISAASKCFASDIAMEVTTDAV
                                      :::* *:*:   **:  : *     .  :  :*  *.: : . .  **

Mb0997c|M.bovis_AF2122/97           QSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
Rv0972c|M.tuberculosis_H37Rv        QSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
MMAR_4535|M.marinum_M               QSMGGNGLTQEYGVAAMLTSSRLARIAPISREMVLNFVAQTSLGLPRSY
MUL_4707|M.ulcerans_Agy99           QSMGGNGLTQEYGVAAMLTSSRLARIAPISREMVLNFVAQTSLGLPRSY
MAV_1088|M.avium_104                QSMGGNGLTKEYGVAAMLASARLGRIAPVSREMVLNFVAQTSLGLPRSY
Mflv_1881|M.gilvum_PYR-GCK          QSLGGNGLTKEYGVAAMLTASRLARIAPVSREMILNFVAQTSLGLPRSY
Mvan_4850|M.vanbaalenii_PYR-1       QSLGGNGLTQEYGIASALTASRLARIAPVSREMILNFVAQTSLGLPRSY
MSMEG_5494|M.smegmatis_MC2_155      QSLGGNGLTKEYGIAAAVTASKLARIAPVSREMILNFVSQTSLGLPRSY
TH_3553|M.thermoresistible__bu      QSLGGNGLTKEYGIAAAITSSRLARIAPISREMILNFVAQTSLGLPRSY
MAB_1070c|M.abscessus_ATCC_199      QSLGGNGLTTEYGVAPLLNLSRFGRIAPVSREMILNFVAQTSLGLPRSY
MLBr_00737|M.leprae_Br4923          QLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-----
                                    * :** * * :: :   :  ::: :*   :.::   .:::: *

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_1881	-	-	100% (386)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_4615	-	e-129	59.84% (381)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_2442	-	2e-68	38.52% (392)	acyl-CoA dehydrogenase domain-containing protein