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MTETNWRGKFDESADLPIDETVPRQREARALLGSLLRPYRWAVVLLAVVVVVENAARLSVPILVQKGIDD GIPPLLEGGPAITLMTIVATLCGVVVVQAVGRMYFLRRSGRIGQKVLLELRRRVFRHFGRLDIAFHDRYT SGRVVSRSTNDVEAIQDMLETGFDSLITAVLTMVGTAVLLVVLDVKLGLMCLVAFPVLVLLVWWFQRESS KTYREVREISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDVADRYREINERTFKLLAVFMPGVKLVGN LTTGVVLLYGGYRALHGEMTIGTLTAFLLYLRMFFEPMQEISQFFNTFQSASSALEKLAGVLAEKPGISD PAKPVRVDEVRGEVALLDVHFAYVPGRPVLPGLDLVIPAGQTVALVGTTGAGKTTIAKLITRFYDPGSGT VSLDGVDLRDMSQADLRRHVVMVTQENFMFGGTIADNIRFGRPGATDDEVRAAARAVGAHTFIDVLPDGY DTDVAKRGGRLSAGQRQLVAFARAFLADPAVLILDEATSSLDIPSERLVQRALETVLADRTAVVIAHRLS TVQIADRVLVLEHGRIVEDGPPEELTAREGGHYAALHRSWVQSLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1748 | - | - | 100% (605) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_2250 | - | 6e-92 | 36.76% (525) | ABC transporter, transmembrane region |
| M. gilvum PYR-GCK | Mflv_1746 | - | 8e-78 | 33.22% (596) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0200 | - | 1e-107 | 40.81% (566) | drugs-transport transmembrane ATP-binding protein ABC transporter |
| M. tuberculosis H37Rv | Rv0194 | - | 1e-107 | 40.81% (566) | drugs-transport transmembrane ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_01113 | - | 1e-86 | 35.88% (485) | putative ABC transporter, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_1414c | - | 6e-95 | 38.02% (484) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_5223 | - | 1e-106 | 40.07% (589) | drug-transport transmembrane ATP-binding protein ABC transporter |
| M. avium 104 | MAV_1420 | - | 2e-89 | 38.14% (506) | ABC transporter |
| M. smegmatis MC2 155 | MSMEG_5659 | - | 0.0 | 80.33% (610) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_3634 | - | 0.0 | 80.91% (503) | PUTATIVE ABC transporter, ATP-binding protein |
| M. ulcerans Agy99 | MUL_4011 | - | 3e-89 | 34.13% (542) | transmembrane ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_5005 | - | 0.0 | 90.50% (600) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAVA
Rv0194|M.tuberculosis_H37Rv MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIA
MMAR_5223|M.marinum_M MRTNWWGRLSRYVLRYRRDLLLGLFASVVGTAITVMVPLVTKRVIDNAIA
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 ADHRPLAPWAVVLVAAAGATYLLTYVRRYYGGRIAHLVQHDLRMDAFQAL
Rv0194|M.tuberculosis_H37Rv ADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQAL
MMAR_5223|M.marinum_M PDHRPLAPWALVLVAAAVAIYFMTFVRRHYGGRIAHLVQHDLRVDAFATL
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
Rv0194|M.tuberculosis_H37Rv LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
MMAR_5223|M.marinum_M MRWDGRQQDRWSSGQLIVRTTNDLELVQTLLFDLPNVIRHLLTLLLCLAV
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
Rv0194|M.tuberculosis_H37Rv MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
MMAR_5223|M.marinum_M MAWLSLPLALLVVLLVPLIGLVAHRSRRLLAVATEAAQERNAVVTGVVDA
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 AVCGIRVVKAFGQEERETVKLVMASRALYAAQLRVARLNAHFGPLLQTLP
Rv0194|M.tuberculosis_H37Rv AVCGIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLP
MMAR_5223|M.marinum_M AVSGIHVVKAFGQQSQETVKLTTAGRALYAARVRVARLNAYFGPLLQSLP
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
Rv0194|M.tuberculosis_H37Rv ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
MMAR_5223|M.marinum_M AFGQMAVLAVGGWMAAQGTITVGTFVAFWSCLTLVSRPACDLAGMLTIAQ
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 QARAGAVRVLELIDSRPTLVDGTKPLSLEARLSLEFQRVSFGYVADRPVL
Rv0194|M.tuberculosis_H37Rv QARAGAVRVLELIDSRPTLVDGTKPLSPEARLSLEFQRVSFGYVADRPVL
MMAR_5223|M.marinum_M QARTGAMRVFELIDSRPTLVDGTKQLPSSTPVSLAFEQASFGYAAEHPVL
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
Rv0194|M.tuberculosis_H37Rv REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
MMAR_5223|M.marinum_M RGIDLSVRPGETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRD
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
Rv0194|M.tuberculosis_H37Rv LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
MMAR_5223|M.marinum_M LTLDSLRSAIGLVPEQAILFSGTIGENISYGRSNVTLEQITAAARAAHID
MLBr_01113|M.leprae_Br4923 --------------------------------------------------
MUL_4011|M.ulcerans_Agy99 --------------------------------------------------
MAV_1420|M.avium_104 --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155 --------------------------------------------------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
Rv0194|M.tuberculosis_H37Rv EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
MMAR_5223|M.marinum_M EFVNTLPDGYATPVGAQGLTLSGGQRQRIALARALVGNPRLLIMDEPTSA
MLBr_01113|M.leprae_Br4923 --------MTMAT-------APA-TRSCDFYCTIRRLLKQLVPQRRLS--
MUL_4011|M.ulcerans_Agy99 --------MTAALNQRPRGGAPAPTRSRDFWGSATRLVKRLAPQRRRS--
MAV_1420|M.avium_104 --------MTTTTRPAPP--APA-GRSRDFWGSAARLVKQLAPQRRTA--
MAB_1414c|M.abscessus_ATCC_199 --------MTRAIGFRGVQQGPA-ERSRDFRGTAIRMVKRLAPQRFLT--
Mflv_1748|M.gilvum_PYR-GCK -------------------------------MTETNWRGKFDE-------
Mvan_5005|M.vanbaalenii_PYR-1 ------------------------------MSADGEWRGKYDE-------
MSMEG_5659|M.smegmatis_MC2_155 -------------------------------MSVTDWRGRLQE-------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
Rv0194|M.tuberculosis_H37Rv VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
MMAR_5223|M.marinum_M VDAVIEASIQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDSGHLLDIG
MLBr_01113|M.leprae_Br4923 ---------------LTVITLGITGTAIGIIVPWVLGHTT----------
MUL_4011|M.ulcerans_Agy99 ---------------LAVIALGIVGTAIGVAVPRILGHAA----------
MAV_1420|M.avium_104 ---------------IAVITLGIAGTVIGVMVPRILGHAT----------
MAB_1414c|M.abscessus_ATCC_199 ---------------ATVITLSMIGIAIGVIGPRILGHAT----------
Mflv_1748|M.gilvum_PYR-GCK -----------------SAD-----LPIDETVPRQREAR-----------
Mvan_5005|M.vanbaalenii_PYR-1 -----------------HTD-----LPIDETVPRRREAR-----------
MSMEG_5659|M.smegmatis_MC2_155 -----------------EQDPNNDNLPIDESIPLRREAR-----------
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
Rv0194|M.tuberculosis_H37Rv TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
MMAR_5223|M.marinum_M TPEQLWGRCSRYRELLSPATDPLRSLAFEDGVPEPESEP-----EAIDVA
MLBr_01113|M.leprae_Br4923 ------------DLLFNGVIGRQLPKGISKTQAVAAARTRGDNALADLLS
MUL_4011|M.ulcerans_Agy99 ------------DLLFNGVIGRQLPAGITKAQAIAGARARGDNTFAELLS
MAV_1420|M.avium_104 ------------DLLFNGVVGRQLPAGISKAQAVAAARSRGQNTFADLLS
MAB_1414c|M.abscessus_ATCC_199 ------------DLLFNGVIGRQLPAGQSREQAVETARARGDGQFAQMLS
Mflv_1748|M.gilvum_PYR-GCK -------------ALLGSLLRPYRWAVVLLAVVVVVENAARLSVPILVQK
Mvan_5005|M.vanbaalenii_PYR-1 -------------SLLYLLLRPYRWVVLALAVVVVVENAARLSVPLLVQK
MSMEG_5659|M.smegmatis_MC2_155 -------------SLLISLLRPYRWIVAVLALVVIVENAARLSVPVLVQR
TH_3634|M.thermoresistible__bu --------------------------------------------------
Mb0200|M.bovis_AF2122/97 VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
Rv0194|M.tuberculosis_H37Rv VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
MMAR_5223|M.marinum_M ADATGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVALETGAGLLPPLLIRH
MLBr_01113|M.leprae_Br4923 GMNLVPG---QGVDFVAVGRTLGLALSLYLVYTLLTWAQARLLNVTVQRI
MUL_4011|M.ulcerans_Agy99 GMKVTPG---QGVDFGAVVRTLALALALYLIASLLIWGQARLLNVTVQRT
MAV_1420|M.avium_104 GMNVVPG---RGVDFGAVARTLALALLLYLVSALLIWVQARLLNRTVQRT
MAB_1414c|M.abscessus_ATCC_199 GMNVIPG---QGVDFHAIGMTLALALSLYLIAGMLAWVQARLLNVTVQRT
Mflv_1748|M.gilvum_PYR-GCK GIDDGIPPLLEGGPAITLMTIVATLCGVVVVQAVGRMYFLRRSGRIGQKV
Mvan_5005|M.vanbaalenii_PYR-1 GIDDGIPPLLAGERATTLLTIVAALCGVVVVQACSRMYFLRRSGRIGQKV
MSMEG_5659|M.smegmatis_MC2_155 GIDHGIPPILAGGPARELMVIVATLCAVVLVQATSRMFFLRRSGRVGQKV
TH_3634|M.thermoresistible__bu ------------------------------------MYFLRRSGRIGQEV
Mb0200|M.bovis_AF2122/97 GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV
Rv0194|M.tuberculosis_H37Rv GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV
MMAR_5223|M.marinum_M GIDVGIR----QHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKA
. :.
MLBr_01113|M.leprae_Br4923 MFALRSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQL
MUL_4011|M.ulcerans_Agy99 VAALRADVEHKLHRLPLSYFDGRQRGELLSRVTNDIDNIQSSLSMTISQL
MAV_1420|M.avium_104 MVALRSAVEDKVHRLPLAYFDGRQRGELLSRVTNDIDNIQSSLSMTISQL
MAB_1414c|M.abscessus_ATCC_199 VVALRTEVENKIHRLPLSYFDSRQRGEILSRVTNDVDNIQTSLQMSINQL
Mflv_1748|M.gilvum_PYR-GCK LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
Mvan_5005|M.vanbaalenii_PYR-1 LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
MSMEG_5659|M.smegmatis_MC2_155 LLELRRRVFRHFQRLDLAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
TH_3634|M.thermoresistible__bu LLELRRRLFRHFQRLDVAFHERYTSGRVVSRSTNDVEAIQDMLETGFDSL
Mb0200|M.bovis_AF2122/97 LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA
Rv0194|M.tuberculosis_H37Rv LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA
MMAR_5223|M.marinum_M LFRLRSLVFAHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIA
: ** : : ** : : ..::: * *:: : * :
MLBr_01113|M.leprae_Br4923 LTSLLTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQ
MUL_4011|M.ulcerans_Agy99 VTAILTVVAVLSMMVWISPLLALITLLTVPLSLLVTRAITRRSQRLFVAH
MAV_1420|M.avium_104 LTSVLTVLTVLAMMLSISPLLAGITLLTVPLSLLATRVIVRRSQRLFVAQ
MAB_1414c|M.abscessus_ATCC_199 LSSMLTLVAVLAMMLSISPLLAVITLATVPLSLWVTRTIARRSQRLFVAQ
Mflv_1748|M.gilvum_PYR-GCK ITAVLTMVGTAVLLVVLDVKLGLMCLVAFPVLVLLVWWFQRESSKTYREV
Mvan_5005|M.vanbaalenii_PYR-1 ITAVLTLVGTAVLLVVLDVKLGLMCLAAFPILVLLVMWFRRESSKTYREV
MSMEG_5659|M.smegmatis_MC2_155 ITAVLTLFGTAVLLVVLDWRLGLMCLAAFPILVALVWWFRNESARTYRKV
TH_3634|M.thermoresistible__bu ITAVLTLGGTAILLVTLDVRLGLMCLGAFPVLIALVWWFREESAKTYRKV
Mb0200|M.bovis_AF2122/97 VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA
Rv0194|M.tuberculosis_H37Rv VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA
MMAR_5223|M.marinum_M IVSLVTAVGILAALLAINAKLALLIFATLPMLGLATWQFRRASSWTYRQA
: :::* :: : * : : :.*: . : . * :
MLBr_01113|M.leprae_Br4923 WTSAGRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQF
MUL_4011|M.ulcerans_Agy99 WTSTGRLNAHIEETYSGFTVVKTFGHQAAAREQFHNLNDDVYQASFGAQL
MAV_1420|M.avium_104 WTSVGRLNAHIEETYSGFTVVQTFGHRAAARDRFRALNDEVYRASFGAQF
MAB_1414c|M.abscessus_ATCC_199 WANTGKLNAHIEETYSGFTIVKTYGHRAEAEAIFADRNAEVYRSAFGAQF
Mflv_1748|M.gilvum_PYR-GCK REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDVADRYREINERTFK
Mvan_5005|M.vanbaalenii_PYR-1 REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDIADRYRVINEKTFK
MSMEG_5659|M.smegmatis_MC2_155 RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFSDIADDYREINEKTFK
TH_3634|M.thermoresistible__bu RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFEQVADDYREINEKTLR
Mb0200|M.bovis_AF2122/97 RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR
Rv0194|M.tuberculosis_H37Rv RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR
MMAR_5223|M.marinum_M RQRLGTVTATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQR
. : . : * :*: .::: . :
MLBr_01113|M.leprae_Br4923 FSGLVSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNM
MUL_4011|M.ulcerans_Agy99 LSALVQPATTFIGNLGYVAVAVMGGLQVATGQITLGSVQAFIQYVRQFNT
MAV_1420|M.avium_104 FSGLVAPATAVIGNLGYAAVAVLGGLQVATGQITLGNIQAFIQYVRQFNS
MAB_1414c|M.abscessus_ATCC_199 FSGLVSPATAFVGNLSYVAVAVVGGLKVASGGLTLGSIQAFSQYVRQFNQ
Mflv_1748|M.gilvum_PYR-GCK LLAVFMPGVKLVGNLTTGVVLLYGGYRALHGEMTIGTLTAFLLYLRMFFE
Mvan_5005|M.vanbaalenii_PYR-1 LLAVFMPGVKLVGNLTTGVVLLYGGYRVLHGEMTIGTLAAFLLYLRMFFE
MSMEG_5659|M.smegmatis_MC2_155 LLAIFMPGVKLVGNITTGVVLIYGGYRVLNDQMTIGTLAAFLLYLRMFFE
TH_3634|M.thermoresistible__bu LLAIFMPGVRLVGNITTGVVLLYGGYLVLNDQMTIGTLTAFLLYLRMFFE
Mb0200|M.bovis_AF2122/97 LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT
Rv0194|M.tuberculosis_H37Rv LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT
MMAR_5223|M.marinum_M LLALYFPLVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFA
: .: * . . .: * *. . . :::* : :: *:. :
MLBr_01113|M.leprae_Br4923 PLSQVAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPH----GQV
MUL_4011|M.ulcerans_Agy99 PVSQVAAMYNSLQSGVASAERVFELLDEPEEAADPASALQPPVS-RTGRA
MAV_1420|M.avium_104 PLSQLAGMYNTLQSGVASAERVFALLDEPEEPPDAPPEEKPTAPGPAGRD
MAB_1414c|M.abscessus_ATCC_199 PLTQVAAMYNTLQSGLASAERVFELLDADEETPDPLAAATAPTG------
Mflv_1748|M.gilvum_PYR-GCK PMQEISQFFNTFQSASSALEKLAGVLAEKPGISDPA---KPVR------V
Mvan_5005|M.vanbaalenii_PYR-1 PMQEISQFFNTFQSAASALEKLAGVLAEKPGISDPP---HPVA------L
MSMEG_5659|M.smegmatis_MC2_155 PMQEISQFFNTFQSASSALEKLAGVLAQRPGIADPE---RPVA------L
TH_3634|M.thermoresistible__bu PMQEISQFFNTFQSAASALEKLAGVLAEEPAIKDPQ---HPVSP-----A
Mb0200|M.bovis_AF2122/97 PIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAA---RPVG-------
Rv0194|M.tuberculosis_H37Rv PIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAA---RPVG-------
MMAR_5223|M.marinum_M PVDKLSQMFDEYQRAAVAVGRIRSLLNTPTAFSPSA---APVG-------
*: ::: ::: * . : :: :* . .
MLBr_01113|M.leprae_Br4923 PRINGRVEFQQVSFAYRT-GTPVIDDLSMVVEPGSTVAIVGPTGAGKTTL
MUL_4011|M.ulcerans_Agy99 PALTGRVEFERVNFAYHP-GHPVIHDLSLVAEPGSTVAIVGPTGAGKTTL
MAV_1420|M.avium_104 AGGGGRVEFAHVSFAYRP-GIRVIDDLSLVAEPGSTVAIVGPTGAGKTTL
MAB_1414c|M.abscessus_ATCC_199 ---SVRVEFEDISFGYSP-GQPVIEGLSLRVEPGQTVAIVGPTGAGKTTL
Mflv_1748|M.gilvum_PYR-GCK DEVRGEVALLDVHFAYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTI
Mvan_5005|M.vanbaalenii_PYR-1 GEVRGEIALRDLTFEYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTI
MSMEG_5659|M.smegmatis_MC2_155 HAVAGTITFDHVHFAYAP-GRPVLPDLTLTVPAGQTVALVGTTGAGKTTI
TH_3634|M.thermoresistible__bu RPVRGEIAFHGVQFAYVP-GRPVIPELTLTVPAGQTVALVGTTGAGKTTI
Mb0200|M.bovis_AF2122/97 -TLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTL
Rv0194|M.tuberculosis_H37Rv -TLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTL
MMAR_5223|M.marinum_M -TLRGEIEFDAVHFRYPTRDAPALAGINLRIPAGQTVVFVGSTGSGKSTL
: : : : * . .: : : .*.**.:**.**:**:*:
MLBr_01113|M.leprae_Br4923 VNLLMRFYDVDSGQILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAE
MUL_4011|M.ulcerans_Agy99 VNLLMRFYEVDSGRILVDGIDITTVSRQSLRSHIGMVLQDTWLFDGTISE
MAV_1420|M.avium_104 VNLLMRFYDVDAGRISIDGVDIATMDRRALRSRIGMVLQDTWLFDGTIAE
MAB_1414c|M.abscessus_ATCC_199 VNLLMRFYEVDSGRILLDGIDVSTMTRHDLRSRMGMVLQDTWLFGGTIVE
Mflv_1748|M.gilvum_PYR-GCK AKLITRFYDPGSGTVSLDGVDLRDMSQADLRRHVVMVTQENFMFGGTIAD
Mvan_5005|M.vanbaalenii_PYR-1 AKLITRFYDPVAGTVMLDEIDLRDVAQAELRRHVVMVTQENFMFGGTVAD
MSMEG_5659|M.smegmatis_MC2_155 AKLIARFYDPTSGTVTLDGVDLRDLSQSELRRHVVMVTQENFMFEGTVAD
TH_3634|M.thermoresistible__bu ATLIARFYDPTAGSVTLDGIDLRDIAQSELRRHVVMVTQENFMFDGTVAD
Mb0200|M.bovis_AF2122/97 IKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRD
Rv0194|M.tuberculosis_H37Rv IKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRD
MMAR_5223|M.marinum_M MKLVSRFYDPTDGIIRVDGCDLREFDIDGYRSRLSIVAQEPYLFAGTVRD
.*: ***: * : :* *: . * :: :* *: ::* **: :
MLBr_01113|M.leprae_Br4923 NIAYGRPQASEDEVMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGEK
MUL_4011|M.ulcerans_Agy99 NIAYGRPEASPDDIIQAAKAAYVDRFVHMLPASYQTRISGDGSNISAGEK
MAV_1420|M.avium_104 NIGYGRPGAGDDEIVAAARAAYVDRFVQNLPDGYHTRVSGDGGNLSAGER
MAB_1414c|M.abscessus_ATCC_199 NIAYGRPGASQEEILEAARAAYVDRFVRTLPDGYDTKIADDGGNISAGEK
Mflv_1748|M.gilvum_PYR-GCK NIRFGRPGATDDEVRAAARAVGAHTFIDVLPDGYDTDVAKRGGRLSAGQR
Mvan_5005|M.vanbaalenii_PYR-1 NIRFGRPDATDDEVRAAARAVGAHTFIGALPDGYDTDVAKRGGRLSAGQR
MSMEG_5659|M.smegmatis_MC2_155 NIRFGRPDATDAQVRAAAEAVGADRFIATLPEGYGTDVAKRGGRLSAGQR
TH_3634|M.thermoresistible__bu NIRFGRPEATDAEIAAAAEAVGADRFIAALPDGYHTDVAKRGSRLSAGQR
Mb0200|M.bovis_AF2122/97 AIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQL
Rv0194|M.tuberculosis_H37Rv AIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQL
MMAR_5223|M.marinum_M AIAYGRPDATDAQVERAAREVGAHPMIAALDGGYQHEVAAGGRNLSAGQL
* :*** * :: **. . .. :: * .* :: * .:***:
MLBr_01113|M.leprae_Br4923 QLITIARAFLARPQLLILDEATSSIDTRTEALIARATHDLLQDRTSFIIA
MUL_4011|M.ulcerans_Agy99 QLITIARAFLARPQLLILDEATSSVDTRTELLIARATAELRRDRTSFIIA
MAV_1420|M.avium_104 QLITIARAFLARPQLLILDEATSSVDTRTEALIAHATRELRRDRTSFIIA
MAB_1414c|M.abscessus_ATCC_199 QLITIARAFLARPQLLILDEATSSVDTRTELRIQRAMAELRRDRTSFIIA
Mflv_1748|M.gilvum_PYR-GCK QLVAFARAFLADPAVLILDEATSSLDIPSERLVQRALETVLADRTAVVIA
Mvan_5005|M.vanbaalenii_PYR-1 QLVAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTAVVIA
MSMEG_5659|M.smegmatis_MC2_155 QLIAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTALVIA
TH_3634|M.thermoresistible__bu QLIAFARAFLADPAVLILDEATSALDIPSERMVQRALRTVLADRTALVIA
Mb0200|M.bovis_AF2122/97 QLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVA
Rv0194|M.tuberculosis_H37Rv QLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVA
MMAR_5223|M.marinum_M QLLALARARLVDSDILLLDEATVALDPATEALVHWATLGLAADRTTLIIA
**:::*** *. . :*:***** ::* :* : * : **:.::*
MLBr_01113|M.leprae_Br4923 HHLPTIRDADHILVVAAGKIVEQGSHAKLLARRGAYYRMTQA--------
MUL_4011|M.ulcerans_Agy99 HRLSTIRDADQILVVQAGQIVEHGTHAELLANRGAYYAMTRA--------
MAV_1420|M.avium_104 HRLSTIRDADRIAVIEAGRIFEQGTHAELLARRGVYYAMTQA--------
MAB_1414c|M.abscessus_ATCC_199 HRLSTIRDADRIVVLDGGRVTESGTHTELLARHGAYFAMTQS--------
Mflv_1748|M.gilvum_PYR-GCK HRLSTVQIADRVLVLEHGRIVEDGPPEELTAREGGHYAALHRSWVQSLA-
Mvan_5005|M.vanbaalenii_PYR-1 HRLSTVQIADRVLVLEHGRIVEDGAPDELTARDHGHYAALHRSWVQSLA-
MSMEG_5659|M.smegmatis_MC2_155 HRLSTVQIADRVLVLEHGRIIEDGSPADLIGRTDGAYAALHRAWVDSLA-
TH_3634|M.thermoresistible__bu HRLSTVEIADRVLVLERGRVVEDGPPGELIRRGEGRYAALHHAWLESLG-
Mb0200|M.bovis_AF2122/97 HGLAIAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSP
Rv0194|M.tuberculosis_H37Rv HGLAIAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSP
MMAR_5223|M.marinum_M HELAIAEFVDRIVVLEQGTIVEDGTHVELLAAG-GRYAALWAAHSRVGRP
* *. . .*:: *: * : * *. .* :
MLBr_01113|M.leprae_Br4923 ----------------------
MUL_4011|M.ulcerans_Agy99 ----------------------
MAV_1420|M.avium_104 ----------------------
MAB_1414c|M.abscessus_ATCC_199 ----------------------
Mflv_1748|M.gilvum_PYR-GCK ----------------------
Mvan_5005|M.vanbaalenii_PYR-1 ----------------------
MSMEG_5659|M.smegmatis_MC2_155 ----------------------
TH_3634|M.thermoresistible__bu ----------------------
Mb0200|M.bovis_AF2122/97 EITQLQCIDA------------
Rv0194|M.tuberculosis_H37Rv EITQLQCIDA------------
MMAR_5223|M.marinum_M SPSDDRPIPTELLVHSPDTDVL