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M. smegmatis MC2 155 MSMEG_5659 (-)

annotation: ABC transporter, ATP-binding protein
coordinates: 5749605 - 5751437
length: 610

SVTDWRGRLQEEQDPNNDNLPIDESIPLRREARSLLISLLRPYRWIVAVLALVVIVENAARLSVPVLVQR
GIDHGIPPILAGGPARELMVIVATLCAVVLVQATSRMFFLRRSGRVGQKVLLELRRRVFRHFQRLDLAFH
DRYTSGRVVSRSTNDVEAIQDMLETGFDSLITAVLTLFGTAVLLVVLDWRLGLMCLAAFPILVALVWWFR
NESARTYRKVRESAALVIVQFVETMTGIKAVQAYRREPRNQEIFSDIADDYREINEKTFKLLAIFMPGVK
LVGNITTGVVLIYGGYRVLNDQMTIGTLAAFLLYLRMFFEPMQEISQFFNTFQSASSALEKLAGVLAQRP
GIADPERPVALHAVAGTITFDHVHFAYAPGRPVLPDLTLTVPAGQTVALVGTTGAGKTTIAKLIARFYDP
TSGTVTLDGVDLRDLSQSELRRHVVMVTQENFMFEGTVADNIRFGRPDATDAQVRAAAEAVGADRFIATL
PEGYGTDVAKRGGRLSAGQRQLIAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTALVIA
HRLSTVQIADRVLVLEHGRIIEDGSPADLIGRTDGAYAALHRAWVDSLA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5659--100% (610)ABC transporter, ATP-binding protein
M. smegmatis MC2 155MSMEG_5009-7e-9237.05% (475) ABC transporter
M. smegmatis MC2 155MSMEG_5008-6e-8232.62% (561) ABC transporter, ATP-binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0200-1e-10739.97% (578) drugs-transport transmembrane ATP-binding protein ABC transporter
M. gilvum PYR-GCKMflv_1748-0.080.33% (610) ABC transporter related
M. tuberculosis H37RvRv0194-1e-10739.97% (578) drugs-transport transmembrane ATP-binding protein ABC transporter
M. leprae Br4923MLBr_01113-6e-8835.85% (491) putative ABC transporter, ATP-binding component
M. abscessus ATCC 19977MAB_1414c-7e-9236.98% (484) ABC transporter ATP-binding protein
M. marinum MMMAR_5223-1e-10438.80% (598) drug-transport transmembrane ATP-binding protein ABC transporter
M. avium 104MAV_1420-6e-9135.77% (548) ABC transporter
M. thermoresistible (build 8)TH_3634-0.084.89% (503) PUTATIVE ABC transporter, ATP-binding protein
M. ulcerans Agy99MUL_4011-8e-9236.64% (494) transmembrane ATP-binding protein ABC transporter
M. vanbaalenii PYR-1Mvan_5005-0.081.19% (606) ABC transporter-related protein

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAVA
Rv0194|M.tuberculosis_H37Rv         MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRVIDDAIA
MMAR_5223|M.marinum_M               MRTNWWGRLSRYVLRYRRDLLLGLFASVVGTAITVMVPLVTKRVIDNAIA
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            ADHRPLAPWAVVLVAAAGATYLLTYVRRYYGGRIAHLVQHDLRMDAFQAL
Rv0194|M.tuberculosis_H37Rv         ADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQAL
MMAR_5223|M.marinum_M               PDHRPLAPWALVLVAAAVAIYFMTFVRRHYGGRIAHLVQHDLRVDAFATL
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
Rv0194|M.tuberculosis_H37Rv         LRWDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAV
MMAR_5223|M.marinum_M               MRWDGRQQDRWSSGQLIVRTTNDLELVQTLLFDLPNVIRHLLTLLLCLAV
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
Rv0194|M.tuberculosis_H37Rv         MTWLSVPLALLAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDA
MMAR_5223|M.marinum_M               MAWLSLPLALLVVLLVPLIGLVAHRSRRLLAVATEAAQERNAVVTGVVDA
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            AVCGIRVVKAFGQEERETVKLVMASRALYAAQLRVARLNAHFGPLLQTLP
Rv0194|M.tuberculosis_H37Rv         AVCGIRVVKAFGQEERETVKLVTASRALYAAQLRVARLNAHFGPLLQTLP
MMAR_5223|M.marinum_M               AVSGIHVVKAFGQQSQETVKLTTAGRALYAARVRVARLNAYFGPLLQSLP
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
Rv0194|M.tuberculosis_H37Rv         ALGQMAVFALGGWMAAQGSITVGTFVAFWACLTLLARPACDLAGMLTIAQ
MMAR_5223|M.marinum_M               AFGQMAVLAVGGWMAAQGTITVGTFVAFWSCLTLVSRPACDLAGMLTIAQ
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            QARAGAVRVLELIDSRPTLVDGTKPLSLEARLSLEFQRVSFGYVADRPVL
Rv0194|M.tuberculosis_H37Rv         QARAGAVRVLELIDSRPTLVDGTKPLSPEARLSLEFQRVSFGYVADRPVL
MMAR_5223|M.marinum_M               QARTGAMRVFELIDSRPTLVDGTKQLPSSTPVSLAFEQASFGYAAEHPVL
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
Rv0194|M.tuberculosis_H37Rv         REISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRE
MMAR_5223|M.marinum_M               RGIDLSVRPGETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRD
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
Rv0194|M.tuberculosis_H37Rv         LTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
MMAR_5223|M.marinum_M               LTLDSLRSAIGLVPEQAILFSGTIGENISYGRSNVTLEQITAAARAAHID
                                                                                      

MLBr_01113|M.leprae_Br4923          --------------------------------------------------
MUL_4011|M.ulcerans_Agy99           --------------------------------------------------
MAV_1420|M.avium_104                --------------------------------------------------
MAB_1414c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5659|M.smegmatis_MC2_155      --------------------------------------------------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5005|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0200|M.bovis_AF2122/97            EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
Rv0194|M.tuberculosis_H37Rv         EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSA
MMAR_5223|M.marinum_M               EFVNTLPDGYATPVGAQGLTLSGGQRQRIALARALVGNPRLLIMDEPTSA
                                                                                      

MLBr_01113|M.leprae_Br4923          --------MTMAT-------APA-TRSCDFYCTIRRLLKQLVPQRRLS--
MUL_4011|M.ulcerans_Agy99           --------MTAALNQRPRGGAPAPTRSRDFWGSATRLVKRLAPQRRRS--
MAV_1420|M.avium_104                --------MTTTTRPAPP--APA-GRSRDFWGSAARLVKQLAPQRRTA--
MAB_1414c|M.abscessus_ATCC_199      --------MTRAIGFRGVQQGPA-ERSRDFRGTAIRMVKRLAPQRFLT--
MSMEG_5659|M.smegmatis_MC2_155      -------------------------------MSVTDWRGRLQE-------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          -------------------------------MTETNWRGKFDE-------
Mvan_5005|M.vanbaalenii_PYR-1       ------------------------------MSADGEWRGKYDE-------
Mb0200|M.bovis_AF2122/97            VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
Rv0194|M.tuberculosis_H37Rv         VDAVIECGIQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVG
MMAR_5223|M.marinum_M               VDAVIEASIQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDSGHLLDIG
                                                                                      

MLBr_01113|M.leprae_Br4923          ---------------LTVITLGITGTAIGIIVPWVLGHTT----------
MUL_4011|M.ulcerans_Agy99           ---------------LAVIALGIVGTAIGVAVPRILGHAA----------
MAV_1420|M.avium_104                ---------------IAVITLGIAGTVIGVMVPRILGHAT----------
MAB_1414c|M.abscessus_ATCC_199      ---------------ATVITLSMIGIAIGVIGPRILGHAT----------
MSMEG_5659|M.smegmatis_MC2_155      -----------------EQDPNNDNLPIDESIPLRREAR-----------
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          -----------------SAD-----LPIDETVPRQREAR-----------
Mvan_5005|M.vanbaalenii_PYR-1       -----------------HTD-----LPIDETVPRRREAR-----------
Mb0200|M.bovis_AF2122/97            TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
Rv0194|M.tuberculosis_H37Rv         TPDEVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTN
MMAR_5223|M.marinum_M               TPEQLWGRCSRYRELLSPATDPLRSLAFEDGVPEPESEP-----EAIDVA
                                                                                      

MLBr_01113|M.leprae_Br4923          ------------DLLFNGVIGRQLPKGISKTQAVAAARTRGDNALADLLS
MUL_4011|M.ulcerans_Agy99           ------------DLLFNGVIGRQLPAGITKAQAIAGARARGDNTFAELLS
MAV_1420|M.avium_104                ------------DLLFNGVVGRQLPAGISKAQAVAAARSRGQNTFADLLS
MAB_1414c|M.abscessus_ATCC_199      ------------DLLFNGVIGRQLPAGQSREQAVETARARGDGQFAQMLS
MSMEG_5659|M.smegmatis_MC2_155      -------------SLLISLLRPYRWIVAVLALVVIVENAARLSVPVLVQR
TH_3634|M.thermoresistible__bu      --------------------------------------------------
Mflv_1748|M.gilvum_PYR-GCK          -------------ALLGSLLRPYRWAVVLLAVVVVVENAARLSVPILVQK
Mvan_5005|M.vanbaalenii_PYR-1       -------------SLLYLLLRPYRWVVLALAVVVVVENAARLSVPLLVQK
Mb0200|M.bovis_AF2122/97            VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
Rv0194|M.tuberculosis_H37Rv         VHNPGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRH
MMAR_5223|M.marinum_M               ADATGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVALETGAGLLPPLLIRH
                                                                                      

MLBr_01113|M.leprae_Br4923          GMNLVPG---QGVDFVAVGRTLGLALSLYLVYTLLTWAQARLLNVTVQRI
MUL_4011|M.ulcerans_Agy99           GMKVTPG---QGVDFGAVVRTLALALALYLIASLLIWGQARLLNVTVQRT
MAV_1420|M.avium_104                GMNVVPG---RGVDFGAVARTLALALLLYLVSALLIWVQARLLNRTVQRT
MAB_1414c|M.abscessus_ATCC_199      GMNVIPG---QGVDFHAIGMTLALALSLYLIAGMLAWVQARLLNVTVQRT
MSMEG_5659|M.smegmatis_MC2_155      GIDHGIPPILAGGPARELMVIVATLCAVVLVQATSRMFFLRRSGRVGQKV
TH_3634|M.thermoresistible__bu      ------------------------------------MYFLRRSGRIGQEV
Mflv_1748|M.gilvum_PYR-GCK          GIDDGIPPLLEGGPAITLMTIVATLCGVVVVQAVGRMYFLRRSGRIGQKV
Mvan_5005|M.vanbaalenii_PYR-1       GIDDGIPPLLAGERATTLLTIVAALCGVVVVQACSRMYFLRRSGRIGQKV
Mb0200|M.bovis_AF2122/97            GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV
Rv0194|M.tuberculosis_H37Rv         GIDVGIR----RHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQV
MMAR_5223|M.marinum_M               GIDVGIR----QHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKA
                                                                               .   :. 

MLBr_01113|M.leprae_Br4923          MFALRSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQL
MUL_4011|M.ulcerans_Agy99           VAALRADVEHKLHRLPLSYFDGRQRGELLSRVTNDIDNIQSSLSMTISQL
MAV_1420|M.avium_104                MVALRSAVEDKVHRLPLAYFDGRQRGELLSRVTNDIDNIQSSLSMTISQL
MAB_1414c|M.abscessus_ATCC_199      VVALRTEVENKIHRLPLSYFDSRQRGEILSRVTNDVDNIQTSLQMSINQL
MSMEG_5659|M.smegmatis_MC2_155      LLELRRRVFRHFQRLDLAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
TH_3634|M.thermoresistible__bu      LLELRRRLFRHFQRLDVAFHERYTSGRVVSRSTNDVEAIQDMLETGFDSL
Mflv_1748|M.gilvum_PYR-GCK          LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
Mvan_5005|M.vanbaalenii_PYR-1       LLELRRRVFRHFGRLDIAFHDRYTSGRVVSRSTNDVEAIQDMLETGFDSL
Mb0200|M.bovis_AF2122/97            LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA
Rv0194|M.tuberculosis_H37Rv         LFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVA
MMAR_5223|M.marinum_M               LFRLRSLVFAHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIA
                                    :  **  :  :  ** :   :    ..:::  * *:: :   *   :   

MLBr_01113|M.leprae_Br4923          LTSLLTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQ
MUL_4011|M.ulcerans_Agy99           VTAILTVVAVLSMMVWISPLLALITLLTVPLSLLVTRAITRRSQRLFVAH
MAV_1420|M.avium_104                LTSVLTVLTVLAMMLSISPLLAGITLLTVPLSLLATRVIVRRSQRLFVAQ
MAB_1414c|M.abscessus_ATCC_199      LSSMLTLVAVLAMMLSISPLLAVITLATVPLSLWVTRTIARRSQRLFVAQ
MSMEG_5659|M.smegmatis_MC2_155      ITAVLTLFGTAVLLVVLDWRLGLMCLAAFPILVALVWWFRNESARTYRKV
TH_3634|M.thermoresistible__bu      ITAVLTLGGTAILLVTLDVRLGLMCLGAFPVLIALVWWFREESAKTYRKV
Mflv_1748|M.gilvum_PYR-GCK          ITAVLTMVGTAVLLVVLDVKLGLMCLVAFPVLVLLVWWFQRESSKTYREV
Mvan_5005|M.vanbaalenii_PYR-1       ITAVLTLVGTAVLLVVLDVKLGLMCLAAFPILVLLVMWFRRESSKTYREV
Mb0200|M.bovis_AF2122/97            VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA
Rv0194|M.tuberculosis_H37Rv         VISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRA
MMAR_5223|M.marinum_M               IVSLVTAVGILAALLAINAKLALLIFATLPMLGLATWQFRRASSWTYRQA
                                    : :::*       :: :   *  : : :.*:    .  : . *   :   

MLBr_01113|M.leprae_Br4923          WTSAGRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQF
MUL_4011|M.ulcerans_Agy99           WTSTGRLNAHIEETYSGFTVVKTFGHQAAAREQFHNLNDDVYQASFGAQL
MAV_1420|M.avium_104                WTSVGRLNAHIEETYSGFTVVQTFGHRAAARDRFRALNDEVYRASFGAQF
MAB_1414c|M.abscessus_ATCC_199      WANTGKLNAHIEETYSGFTIVKTYGHRAEAEAIFADRNAEVYRSAFGAQF
MSMEG_5659|M.smegmatis_MC2_155      RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFSDIADDYREINEKTFK
TH_3634|M.thermoresistible__bu      RESAALVIVQFVETMTGIKAVQAYRREPRNQEIFEQVADDYREINEKTLR
Mflv_1748|M.gilvum_PYR-GCK          REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDVADRYREINERTFK
Mvan_5005|M.vanbaalenii_PYR-1       REISALVIVQFVETMTGIKAVQAYRREPRNQQIFEDIADRYRVINEKTFK
Mb0200|M.bovis_AF2122/97            RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR
Rv0194|M.tuberculosis_H37Rv         RHRLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQR
MMAR_5223|M.marinum_M               RQRLGTVTATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQR
                                        . : . : *  :*:  .:::  .      :                

MLBr_01113|M.leprae_Br4923          FSGLVSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNM
MUL_4011|M.ulcerans_Agy99           LSALVQPATTFIGNLGYVAVAVMGGLQVATGQITLGSVQAFIQYVRQFNT
MAV_1420|M.avium_104                FSGLVAPATAVIGNLGYAAVAVLGGLQVATGQITLGNIQAFIQYVRQFNS
MAB_1414c|M.abscessus_ATCC_199      FSGLVSPATAFVGNLSYVAVAVVGGLKVASGGLTLGSIQAFSQYVRQFNQ
MSMEG_5659|M.smegmatis_MC2_155      LLAIFMPGVKLVGNITTGVVLIYGGYRVLNDQMTIGTLAAFLLYLRMFFE
TH_3634|M.thermoresistible__bu      LLAIFMPGVRLVGNITTGVVLLYGGYLVLNDQMTIGTLTAFLLYLRMFFE
Mflv_1748|M.gilvum_PYR-GCK          LLAVFMPGVKLVGNLTTGVVLLYGGYRALHGEMTIGTLTAFLLYLRMFFE
Mvan_5005|M.vanbaalenii_PYR-1       LLAVFMPGVKLVGNLTTGVVLLYGGYRVLHGEMTIGTLAAFLLYLRMFFE
Mb0200|M.bovis_AF2122/97            LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT
Rv0194|M.tuberculosis_H37Rv         LLALYYPFVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYT
MMAR_5223|M.marinum_M               LLALYFPLVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFA
                                    : .:  * . .  .:    *   *.  .  . :::* : ::  *:. :  

MLBr_01113|M.leprae_Br4923          PLSQVAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPH----GQV
MUL_4011|M.ulcerans_Agy99           PVSQVAAMYNSLQSGVASAERVFELLDEPEEAADPASALQPPVS-RTGRA
MAV_1420|M.avium_104                PLSQLAGMYNTLQSGVASAERVFALLDEPEEPPDAPPEEKPTAPGPAGRD
MAB_1414c|M.abscessus_ATCC_199      PLTQVAAMYNTLQSGLASAERVFELLDADEETPDPLAAATAPTG------
MSMEG_5659|M.smegmatis_MC2_155      PMQEISQFFNTFQSASSALEKLAGVLAQRPGIADPE---RPVA------L
TH_3634|M.thermoresistible__bu      PMQEISQFFNTFQSAASALEKLAGVLAEEPAIKDPQ---HPVSP-----A
Mflv_1748|M.gilvum_PYR-GCK          PMQEISQFFNTFQSASSALEKLAGVLAEKPGISDPA---KPVR------V
Mvan_5005|M.vanbaalenii_PYR-1       PMQEISQFFNTFQSAASALEKLAGVLAEKPGISDPP---HPVA------L
Mb0200|M.bovis_AF2122/97            PIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAA---RPVG-------
Rv0194|M.tuberculosis_H37Rv         PIGELAQMFDDYQRAAVAAGRIRSLLSTRTPSSPAA---RPVG-------
MMAR_5223|M.marinum_M               PVDKLSQMFDEYQRAAVAVGRIRSLLNTPTAFSPSA---APVG-------
                                    *: ::: :::  * .  :  ::  :*        .     .         

MLBr_01113|M.leprae_Br4923          PRINGRVEFQQVSFAYRT-GTPVIDDLSMVVEPGSTVAIVGPTGAGKTTL
MUL_4011|M.ulcerans_Agy99           PALTGRVEFERVNFAYHP-GHPVIHDLSLVAEPGSTVAIVGPTGAGKTTL
MAV_1420|M.avium_104                AGGGGRVEFAHVSFAYRP-GIRVIDDLSLVAEPGSTVAIVGPTGAGKTTL
MAB_1414c|M.abscessus_ATCC_199      ---SVRVEFEDISFGYSP-GQPVIEGLSLRVEPGQTVAIVGPTGAGKTTL
MSMEG_5659|M.smegmatis_MC2_155      HAVAGTITFDHVHFAYAP-GRPVLPDLTLTVPAGQTVALVGTTGAGKTTI
TH_3634|M.thermoresistible__bu      RPVRGEIAFHGVQFAYVP-GRPVIPELTLTVPAGQTVALVGTTGAGKTTI
Mflv_1748|M.gilvum_PYR-GCK          DEVRGEVALLDVHFAYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTI
Mvan_5005|M.vanbaalenii_PYR-1       GEVRGEIALRDLTFEYVP-GRPVLPGLDLVIPAGQTVALVGTTGAGKTTI
Mb0200|M.bovis_AF2122/97            -TLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTL
Rv0194|M.tuberculosis_H37Rv         -TLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTVVFVGSTGSGKSTL
MMAR_5223|M.marinum_M               -TLRGEIEFDAVHFRYPTRDAPALAGINLRIPAGQTVVFVGSTGSGKSTL
                                          : :  : : * .    .:  : :   .*.**.:**.**:**:*:

MLBr_01113|M.leprae_Br4923          VNLLMRFYDVDSGQILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAE
MUL_4011|M.ulcerans_Agy99           VNLLMRFYEVDSGRILVDGIDITTVSRQSLRSHIGMVLQDTWLFDGTISE
MAV_1420|M.avium_104                VNLLMRFYDVDAGRISIDGVDIATMDRRALRSRIGMVLQDTWLFDGTIAE
MAB_1414c|M.abscessus_ATCC_199      VNLLMRFYEVDSGRILLDGIDVSTMTRHDLRSRMGMVLQDTWLFGGTIVE
MSMEG_5659|M.smegmatis_MC2_155      AKLIARFYDPTSGTVTLDGVDLRDLSQSELRRHVVMVTQENFMFEGTVAD
TH_3634|M.thermoresistible__bu      ATLIARFYDPTAGSVTLDGIDLRDIAQSELRRHVVMVTQENFMFDGTVAD
Mflv_1748|M.gilvum_PYR-GCK          AKLITRFYDPGSGTVSLDGVDLRDMSQADLRRHVVMVTQENFMFGGTIAD
Mvan_5005|M.vanbaalenii_PYR-1       AKLITRFYDPVAGTVMLDEIDLRDVAQAELRRHVVMVTQENFMFGGTVAD
Mb0200|M.bovis_AF2122/97            IKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRD
Rv0194|M.tuberculosis_H37Rv         IKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFAGTVRD
MMAR_5223|M.marinum_M               MKLVSRFYDPTDGIIRVDGCDLREFDIDGYRSRLSIVAQEPYLFAGTVRD
                                     .*: ***:   * : :*  *:  .     * :: :* *: ::* **: :

MLBr_01113|M.leprae_Br4923          NIAYGRPQASEDEVMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGEK
MUL_4011|M.ulcerans_Agy99           NIAYGRPEASPDDIIQAAKAAYVDRFVHMLPASYQTRISGDGSNISAGEK
MAV_1420|M.avium_104                NIGYGRPGAGDDEIVAAARAAYVDRFVQNLPDGYHTRVSGDGGNLSAGER
MAB_1414c|M.abscessus_ATCC_199      NIAYGRPGASQEEILEAARAAYVDRFVRTLPDGYDTKIADDGGNISAGEK
MSMEG_5659|M.smegmatis_MC2_155      NIRFGRPDATDAQVRAAAEAVGADRFIATLPEGYGTDVAKRGGRLSAGQR
TH_3634|M.thermoresistible__bu      NIRFGRPEATDAEIAAAAEAVGADRFIAALPDGYHTDVAKRGSRLSAGQR
Mflv_1748|M.gilvum_PYR-GCK          NIRFGRPGATDDEVRAAARAVGAHTFIDVLPDGYDTDVAKRGGRLSAGQR
Mvan_5005|M.vanbaalenii_PYR-1       NIRFGRPDATDDEVRAAARAVGAHTFIGALPDGYDTDVAKRGGRLSAGQR
Mb0200|M.bovis_AF2122/97            AIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQL
Rv0194|M.tuberculosis_H37Rv         AIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQL
MMAR_5223|M.marinum_M               AIAYGRPDATDAQVERAAREVGAHPMIAALDGGYQHEVAAGGRNLSAGQL
                                     * :*** *   ::  **. . .. ::  *  .*   ::  * .:***: 

MLBr_01113|M.leprae_Br4923          QLITIARAFLARPQLLILDEATSSIDTRTEALIARATHDLLQDRTSFIIA
MUL_4011|M.ulcerans_Agy99           QLITIARAFLARPQLLILDEATSSVDTRTELLIARATAELRRDRTSFIIA
MAV_1420|M.avium_104                QLITIARAFLARPQLLILDEATSSVDTRTEALIAHATRELRRDRTSFIIA
MAB_1414c|M.abscessus_ATCC_199      QLITIARAFLARPQLLILDEATSSVDTRTELRIQRAMAELRRDRTSFIIA
MSMEG_5659|M.smegmatis_MC2_155      QLIAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTALVIA
TH_3634|M.thermoresistible__bu      QLIAFARAFLADPAVLILDEATSALDIPSERMVQRALRTVLADRTALVIA
Mflv_1748|M.gilvum_PYR-GCK          QLVAFARAFLADPAVLILDEATSSLDIPSERLVQRALETVLADRTAVVIA
Mvan_5005|M.vanbaalenii_PYR-1       QLVAFARAFLADPAVLILDEATSSLDIPSERMVQRALETVLADRTAVVIA
Mb0200|M.bovis_AF2122/97            QLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVA
Rv0194|M.tuberculosis_H37Rv         QLLALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVA
MMAR_5223|M.marinum_M               QLLALARARLVDSDILLLDEATVALDPATEALVHWATLGLAADRTTLIIA
                                    **:::*** *. . :*:***** ::*  :*  :  *   :   **:.::*

MLBr_01113|M.leprae_Br4923          HHLPTIRDADHILVVAAGKIVEQGSHAKLLARRGAYYRMTQA--------
MUL_4011|M.ulcerans_Agy99           HRLSTIRDADQILVVQAGQIVEHGTHAELLANRGAYYAMTRA--------
MAV_1420|M.avium_104                HRLSTIRDADRIAVIEAGRIFEQGTHAELLARRGVYYAMTQA--------
MAB_1414c|M.abscessus_ATCC_199      HRLSTIRDADRIVVLDGGRVTESGTHTELLARHGAYFAMTQS--------
MSMEG_5659|M.smegmatis_MC2_155      HRLSTVQIADRVLVLEHGRIIEDGSPADLIGRTDGAYAALHRAWVDSLA-
TH_3634|M.thermoresistible__bu      HRLSTVEIADRVLVLERGRVVEDGPPGELIRRGEGRYAALHHAWLESLG-
Mflv_1748|M.gilvum_PYR-GCK          HRLSTVQIADRVLVLEHGRIVEDGPPEELTAREGGHYAALHRSWVQSLA-
Mvan_5005|M.vanbaalenii_PYR-1       HRLSTVQIADRVLVLEHGRIVEDGAPDELTARDHGHYAALHRSWVQSLA-
Mb0200|M.bovis_AF2122/97            HGLAIAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSP
Rv0194|M.tuberculosis_H37Rv         HGLAIAEHADRIVVLEHGTVVEDGAHTELLAAG-GHYSRLWAAHTRLCSP
MMAR_5223|M.marinum_M               HELAIAEFVDRIVVLEQGTIVEDGTHVELLAAG-GRYAALWAAHSRVGRP
                                    * *.  . .*:: *:  * : * *.  .*       :             

MLBr_01113|M.leprae_Br4923          ----------------------
MUL_4011|M.ulcerans_Agy99           ----------------------
MAV_1420|M.avium_104                ----------------------
MAB_1414c|M.abscessus_ATCC_199      ----------------------
MSMEG_5659|M.smegmatis_MC2_155      ----------------------
TH_3634|M.thermoresistible__bu      ----------------------
Mflv_1748|M.gilvum_PYR-GCK          ----------------------
Mvan_5005|M.vanbaalenii_PYR-1       ----------------------
Mb0200|M.bovis_AF2122/97            EITQLQCIDA------------
Rv0194|M.tuberculosis_H37Rv         EITQLQCIDA------------
MMAR_5223|M.marinum_M               SPSDDRPIPTELLVHSPDTDVL