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MAVFDRLSIRVAAVGAGLCGIALAVSPGVAHAGGAECLQTSAGQDPAATAPCAPVAEMSGVPMALPGPVP PPMAPPPVVPPVVPPLAPPPVVPPVVPPLAPPPVVPPIPAAGAAGGLPVASMGGLAGKGDLTGPAPSGAP VPGQPIPPGPTGGN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1398 | - | - | 100% (155) | hypothetical protein Mflv_1398 |
| M. gilvum PYR-GCK | Mflv_3345 | - | 4e-13 | 34.19% (155) | fibronectin-attachment family protein |
| M. gilvum PYR-GCK | Mflv_3843 | - | 5e-11 | 34.01% (147) | hypothetical protein Mflv_3843 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1470c | - | 3e-23 | 37.81% (201) | proline, glycine, valine-rich secreted protein |
| M. tuberculosis H37Rv | Rv1435c | - | 2e-23 | 38.66% (194) | proline, glycine, valine-rich secreted protein |
| M. leprae Br4923 | MLBr_00568 | - | 1e-18 | 39.41% (170) | hypothetical protein MLBr_00568 |
| M. abscessus ATCC 19977 | MAB_4537c | - | 1e-08 | 33.82% (136) | hypothetical protein MAB_4537c |
| M. marinum M | MMAR_2238 | - | 2e-20 | 31.05% (248) | hypothetical protein MMAR_2238 |
| M. avium 104 | MAV_4835 | - | 5e-27 | 42.63% (190) | hypothetical protein MAV_4835 |
| M. smegmatis MC2 155 | MSMEG_0673 | - | 2e-41 | 55.31% (179) | hypothetical protein MSMEG_0673 |
| M. thermoresistible (build 8) | TH_1738 | - | 4e-06 | 38.37% (86) | MCE-FAMILY PROTEIN MCE4F |
| M. ulcerans Agy99 | MUL_1827 | - | 3e-25 | 38.83% (188) | hypothetical protein MUL_1827 |
| M. vanbaalenii PYR-1 | Mvan_3343 | - | 7e-12 | 38.62% (145) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1398|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0673|M.smegmatis_MC2_155 --------------------------------------------------
Mb1470c|M.bovis_AF2122/97 --------------------------------------------------
Rv1435c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2238|M.marinum_M --------------------------------------------------
MUL_1827|M.ulcerans_Agy99 --------------------------------------------------
MAV_4835|M.avium_104 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1738|M.thermoresistible__bu MLSRLVRMQLAVFTAVALISVLAIAVFYIQVPKTLGFGSYRVTADFAGSG
MAB_4537c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1398|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0673|M.smegmatis_MC2_155 --------------------------------------------------
Mb1470c|M.bovis_AF2122/97 --------------------------------------------------
Rv1435c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2238|M.marinum_M --------------------------------------------------
MUL_1827|M.ulcerans_Agy99 --------------------------------------------------
MAV_4835|M.avium_104 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1738|M.thermoresistible__bu GIYPNANVAYRGTTIGKVTGVSLTHDNDVRVEMRIDDDRKVPANVNAYVK
MAB_4537c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1398|M.gilvum_PYR-GCK -------------------------------------------------M
MSMEG_0673|M.smegmatis_MC2_155 --------------------------------------------------
Mb1470c|M.bovis_AF2122/97 -----------------------------------------------MTL
Rv1435c|M.tuberculosis_H37Rv -----------------------------------------------MTL
MMAR_2238|M.marinum_M ------------------------------MLLHQLIAEVPGANKEESAL
MUL_1827|M.ulcerans_Agy99 ------------------------------MLLHQLIAEVPGANKEESAL
MAV_4835|M.avium_104 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 -------------------------------------------MRVRRKM
TH_1738|M.thermoresistible__bu SMSAIGEQYVDLVPPEHASTESLRGGSHIGRDRTFINGDIAGMLREAQAL
MAB_4537c|M.abscessus_ATCC_199 -------------------------------------------------M
Mflv_1398|M.gilvum_PYR-GCK MAVFDRLSIRVAAVG--AGLCGIALAVSPGVAHA------GGAECLQTSA
MSMEG_0673|M.smegmatis_MC2_155 MAIFDRFNCGVVAAG--AALCGVALVLSP-VASAVTPLVTGGDACLYEQA
Mb1470c|M.bovis_AF2122/97 MAIVNRFNIKVIAG---AGLFAAAIALSPDAAAD--PLMTGGYACIQGMA
Rv1435c|M.tuberculosis_H37Rv MAIVNRFNIKVIAG---AGLFAAAIALSPDAAAD--PLMTGGYACIQGMA
MMAR_2238|M.marinum_M MTIFDRFNFKVVAC---AGLCGAAIALSPQAAAV--PLKTDGYACIQGMA
MUL_1827|M.ulcerans_Agy99 MTIFDRFNFKVVAC---AGLCGAAIALSPQAAAV--PLKTDGYACIQGMA
MAV_4835|M.avium_104 MAIVDRFNMKVVAS---AGLCGAAIALSPDAAAA--PLITGGHACIQGQS
MLBr_00568|M.leprae_Br4923 MKVFDRFNTAILVS---AGLCGAALAFSPSAAAAPLSMPTGGPTCIEQMA
Mvan_3343|M.vanbaalenii_PYR-1 SPSMNRISVTTLAAL--GMVWPFLFYGAPAAAEP-----SPGVPCLEILQ
TH_1738|M.thermoresistible__bu VDSLDRSRLRDVLKETFAAFNGSGPELARLLESS-RLLVEEAGDATDDTI
MAB_4537c|M.abscessus_ATCC_199 LVLTRWFRRALVSGVCVAGLLGAGVVPALADPGD------PPDPGIEEPG
. . :
Mflv_1398|M.gilvum_PYR-GCK GQ--------DPAATAPC---------------APVAEMS--GVPMALPG
MSMEG_0673|M.smegmatis_MC2_155 GT--------VGAAGAPAGAGAAPVGAA--CAAAPISEMAA-GVPLAPPG
Mb1470c|M.bovis_AF2122/97 GD-------APVAAGDPVAAGGPAATGA---CSAALTDMA--GVPFVAPG
Rv1435c|M.tuberculosis_H37Rv GD-------APVAAGDPVAAGGPAAAGA---CSAALTDMA--GVPFVAPG
MMAR_2238|M.marinum_M GEGGAPAAGGPAAAGGPAAAGGPAAAGATCAASAPINDMA--GVPMAVPG
MUL_1827|M.ulcerans_Agy99 GEGGAPAAGGPAAAGGPAAAGGPAAAGATCAASAPINDMA--GVPMAVPG
MAV_4835|M.avium_104 GE-VAPAAGGPVAGGAP-AAGGAVAAGATDMCAAPLTDMS--GVPMAVPG
MLBr_00568|M.leprae_Br4923 GLG-------AVPAAVPAVLPGPVAGAVP---SVPVVPSGG-FPPVVPPG
Mvan_3343|M.vanbaalenii_PYR-1 QLAAAPPSVPETLDTAANALNNVVPEAAPALPPVPVAEVVHGLTALAAPG
TH_1738|M.thermoresistible__bu GLVEQSQPLLDAQVTAGDDIRAVADGLARLTSHLREADPQFREVLQKAPA
MAB_4537c|M.abscessus_ATCC_199 PP---------PPPPLPWELPPPPPPPAPDAPPPAEVPPVPAPVPTTPPP
*
Mflv_1398|M.gilvum_PYR-GCK PVPP----PMAPPPVVPP--------VVPP---------LAPP-PVVPPV
MSMEG_0673|M.smegmatis_MC2_155 PVPPV---PVAPPPVVPP--------VVPPP--------LAPPVPPVPPV
Mb1470c|M.bovis_AF2122/97 PVPAAAPVPIGAPVPIPGAPVPIPGAPVPIPGAPVPIPGGPVPIPGAPVP
Rv1435c|M.tuberculosis_H37Rv PVPAAAPVPIGAPVPIPGAPVPIPGAPVPIP-------GGPVPIPGAPVP
MMAR_2238|M.marinum_M PIPV---LPAGAPLIDLG------GAAAAAP----------VPIP-AAAP
MUL_1827|M.ulcerans_Agy99 PIPV---LPAGAPLIDLG------GAAAAAP----------VPIP-AAAP
MAV_4835|M.avium_104 PVP------LGAPVPVPL------GAPLPLG----------APVP-LAPP
MLBr_00568|M.leprae_Br4923 GFPPVVP-PGGFLPVVPP-------GGFPPV----------VPPGGFPPV
Mvan_3343|M.vanbaalenii_PYR-1 PVPPVDAAPLAAPPVPPVDAAPLAAPLVQAAAG---PVPAAAPIPVVAPP
TH_1738|M.thermoresistible__bu AADQATTLFDGIRPTFPVLAANLANAGRIGVIYHKSIEQVLVIIPAVTAA
MAB_4537c|M.abscessus_ATCC_199 GAPPTGDVPPLPVGLLKNSPNNGDVVGVAQP----------ITIVFAAPV
.
Mflv_1398|M.gilvum_PYR-GCK VPPLAPP-------------------------------------------
MSMEG_0673|M.smegmatis_MC2_155 VPPAGVP-------------------------------------------
Mb1470c|M.bovis_AF2122/97 VPAVPAP-------------------------------------------
Rv1435c|M.tuberculosis_H37Rv VPAVPAP-------------------------------------------
MMAR_2238|M.marinum_M VP-IPAGAPVPIPAGAPIPIPAGAPIPIPAGAPIPIPAGAPIPIPAGAPI
MUL_1827|M.ulcerans_Agy99 VP-IPAG-------------------------------------------
MAV_4835|M.avium_104 VPVVPAG-------------------------------------------
MLBr_00568|M.leprae_Br4923 VPPGVAP-------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 IPAVIPLAPPVPVVAPPPAVPVAAP-------------------------
TH_1738|M.thermoresistible__bu IIAIANQFPADEGAKGDFKLNFGDPPPCITG-------------------
MAB_4537c|M.abscessus_ATCC_199 TDKKAAEA------------------------------------------
Mflv_1398|M.gilvum_PYR-GCK ----------------------PVVP-PIPAAG--------AAGGLPVAS
MSMEG_0673|M.smegmatis_MC2_155 ----------------------PIAAAPIAAAAGPIAP---AAAGAPLLE
Mb1470c|M.bovis_AF2122/97 ----------------VIPVGTPLIALG-PVLAGAPGD---GVVSAPIIG
Rv1435c|M.tuberculosis_H37Rv ----------------VIPVGTPLIALG-PVLAGAPGD---GVVSAPIIG
MMAR_2238|M.marinum_M PIPAGAPIPIAAGAPVPIPAGVPLIALG-PVPAGVP------AAGAPIID
MUL_1827|M.ulcerans_Agy99 ---------------------VSLIALG-PVPAGVP------AAGAPIID
MAV_4835|M.avium_104 ---------------------APLIALGGPAAAGAPV-----EAAAPIID
MLBr_00568|M.leprae_Br4923 -------------------AVGPLLAEDSAALGSGILAGKGVPTASPQAA
Mvan_3343|M.vanbaalenii_PYR-1 ------------VEAVLASAPEPVAPAPVPPAPGEAAPVELAAAPPPVEP
TH_1738|M.thermoresistible__bu ---------FVPPSEIRSPADTTLRDVPKELYCKVPHNDPAVVRGARNYP
MAB_4537c|M.abscessus_ATCC_199 ---------------------AVKITTSKPAPGYFYWYTDQQLRWKPTQF
Mflv_1398|M.gilvum_PYR-GCK MGGLAGKGDLTG-------------PAPSGAPVPGQPIPPGPTGGN----
MSMEG_0673|M.smegmatis_MC2_155 MSGLGGKGQPTG-------------PAPAGAPAPGQPAMPGPQH------
Mb1470c|M.bovis_AF2122/97 MSGV--KDALTD-------------PAPAGGPVPGQPVLPGPSASAPAGA
Rv1435c|M.tuberculosis_H37Rv MSGV--KDALTD-------------PAPAGGPVPGQPVLPGPSASAPAGA
MMAR_2238|M.marinum_M MSGTG-KDGPIG-------------PAPAGGPVAGQPVQPGPSGAGAG--
MUL_1827|M.ulcerans_Agy99 MSGTG-KDGPIG-------------PAPAGGPVAGQPVQPGPSGAGAG--
MAV_4835|M.avium_104 MSGV--KDAPTG-------------PAPTGGPVPGQPVRPGPSGAS----
MLBr_00568|M.leprae_Br4923 LSGLVVLPGPPAS----------VEAPPAAAPVVAAATPLLCCGEAAPPV
Mvan_3343|M.vanbaalenii_PYR-1 APPAPPEPPPTAPTDVAPAVAEPVAPEPVMAPAAAEPTPAAVAPVEPGPA
TH_1738|M.thermoresistible__bu CMEFPGKRAATVQQCRDPEGYVPIGSNPWRGPPVPVGTPITDPRMILPQN
MAB_4537c|M.abscessus_ATCC_199 WPANTDVNVNAGG-----TKWSFKVGDAFVSTVDDATYTMTVTRNGVVER
. ..
Mflv_1398|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0673|M.smegmatis_MC2_155 --------------------------------------------------
Mb1470c|M.bovis_AF2122/97 R-------------------------------------------------
Rv1435c|M.tuberculosis_H37Rv R-------------------------------------------------
MMAR_2238|M.marinum_M --------------------------------------------------
MUL_1827|M.ulcerans_Agy99 --------------------------------------------------
MAV_4835|M.avium_104 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 R-------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 PVELVAAAEPAPIMEPAAAPVESAPVFHAAAVPPALPGPVVPVVPAGVPV
TH_1738|M.thermoresistible__bu KYPYIPPQADYDPGPPVVQLPPGVPPGPGPALTPPYPTQIPPVTPGPPPP
MAB_4537c|M.abscessus_ATCC_199 TMPISMGKHDKKHETKNGTYYVSEKFQKMVMDSSTYGVPVNSAEGYKLDV
Mflv_1398|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0673|M.smegmatis_MC2_155 --------------------------------------------------
Mb1470c|M.bovis_AF2122/97 --------------------------------------------------
Rv1435c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2238|M.marinum_M --------------------------------------------------
MUL_1827|M.ulcerans_Agy99 --------------------------------------------------
MAV_4835|M.avium_104 --------------------------------------------------
MLBr_00568|M.leprae_Br4923 --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 PVAPVGVPVPVVPTGAPAAVPAPPLGLPAVPLGDAVPGVPFLPATLPIPQ
TH_1738|M.thermoresistible__bu PLPFQPPPDQIVPPYGRPPAPPPPAEGDRPQAAGVDVATYDPATGKFLDP
MAB_4537c|M.abscessus_ATCC_199 YWATRLSNSGIFVHAAPWSVGAQGKSDTSHGCINVNTDNATWFFNQSHPG
Mflv_1398|M.gilvum_PYR-GCK ----------------------------------
MSMEG_0673|M.smegmatis_MC2_155 ----------------------------------
Mb1470c|M.bovis_AF2122/97 ----------------------------------
Rv1435c|M.tuberculosis_H37Rv ----------------------------------
MMAR_2238|M.marinum_M ----------------------------------
MUL_1827|M.ulcerans_Agy99 ----------------------------------
MAV_4835|M.avium_104 ----------------------------------
MLBr_00568|M.leprae_Br4923 ----------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 DLVCEGTAWSAGRTAPEGDAAALDAPPGQRRDQW
TH_1738|M.thermoresistible__bu HTGISVYASGIAAPSIAENWVDLMTYPRTGSEPA
MAB_4537c|M.abscessus_ATCC_199 DPVIVKNSPGGPYKDYDGYDDWQRF---------