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RNRLRRTAESAIVYPQPGGSIEEDGALTRAHTATGHGIGQGAASTKGGPVIEIDHVTKRFGDYLAVSDAD FSIASGEFFSMLGPSGCGKTTTLRMIAGFETPSEGAIRLEGADVSKTPPNKRNVNTVFQHYALFPHMTVW DNVAYGPRSKKLDKGEIRKRVDELLEIVRLSDFAERKPAQLSGGQQQRVALARALVNYPSALLLDEPLGA LDLKLRHVMQFELKRIQREIGITFIYVTHDQEEALTMSDRIAVMNAGNVEQIGTPTEIYDRPATVFVASF IGQANLWAGRQTGRTNRDFVEIDVLGSTLKARPGETTIEPGGHATLMVRPERVRVSMDAPTGDVAGVRAT VSDLTFQGPVVRLSLAAPDDSTVIAHVGPEQDLPLLRPGDEVYVSWAPDASLVLPGADIPTTEDLEEMLD DS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3138 | - | - | 100% (423) | spermidine/putrescine ABC transporter ATPase subunit |
| M. gilvum PYR-GCK | Mflv_1083 | - | 1e-70 | 41.78% (359) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_2681 | - | 9e-70 | 53.45% (232) | sulfate ABC transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-68 | 41.33% (346) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-68 | 41.33% (346) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 4e-66 | 51.50% (233) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_1655 | - | 8e-72 | 42.25% (355) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 8e-70 | 43.02% (351) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 1e-69 | 41.55% (361) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_3281 | - | 0.0 | 81.28% (422) | spermidine/putrescine ABC transporter ATP-binding subunit |
| M. thermoresistible (build 8) | TH_2424 | - | 3e-67 | 42.36% (347) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 2e-69 | 42.74% (351) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_3387 | - | 0.0 | 95.71% (373) | spermidine/putrescine ABC transporter ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3138|M.gilvum_PYR-GCK MRNRLRRTAESAIVYPQPGGSIEEDGALT--RAHTATGHGIGQ-GAASTK
Mvan_3387|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3281|M.smegmatis_MC2_155 ----MRTSAESAKVYPQPLRLHLRRTTLTGPDTTAAVDHSAGQSGEPRKS
Mb2419c|M.bovis_AF2122/97 ------------------------------------------MT------
Rv2397c|M.tuberculosis_H37Rv ------------------------------------------MT------
MMAR_3715|M.marinum_M ------------------------------------MKKETSLTGPGT--
MUL_3658|M.ulcerans_Agy99 ------------------------------------------MTGPGT--
MAV_1785|M.avium_104 ------------------------------------------MTDAGTDR
TH_2424|M.thermoresistible__bu ------------------------------------------MT------
MAB_1655|M.abscessus_ATCC_1997 ------------------------------------------MT------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mflv_3138|M.gilvum_PYR-GCK GGPVIEIDHVTKRFG-DYLAVSDADFSIASGEFFSMLGPSGCGKTTTLRM
Mvan_3387|M.vanbaalenii_PYR-1 ---MIEIDHVTKSFG-DYVAVADADFSIASGEFFSMLGPSGCGKTTTLRM
MSMEG_3281|M.smegmatis_MC2_155 GAPVIEIDHVTKRFA-DYVAVADADFSIAQGEFFSMLGPSGCGKTTTLRM
Mb2419c|M.bovis_AF2122/97 --YAIVVADATKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRT
Rv2397c|M.tuberculosis_H37Rv --YAIVVADATKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRT
MMAR_3715|M.marinum_M GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRT
MUL_3658|M.ulcerans_Agy99 GGHAIVVRDAFKQYG-DFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRT
MAV_1785|M.avium_104 GDIAITVRDAYKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRT
TH_2424|M.thermoresistible__bu --DAITVRGANKRYG-DFAALDNVDFAVPAGSLTALLGPSGSGKSTLLRA
MAB_1655|M.abscessus_ATCC_1997 AENTITVRGANKHYG-DFAALDNIDFDVPSGSLTALLGPSGSGKSTLLRS
MLBr_01089|M.leprae_Br4923 -MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLILIGPSGCGKTTTLNM
* : . * : . *: . .: :. *.: ::****.**:* *.
Mflv_3138|M.gilvum_PYR-GCK IAGFETPSEGAIRLEGADVSKTPPNKRNVNTVFQHYALFPHMTVWDNVAY
Mvan_3387|M.vanbaalenii_PYR-1 IAGFETPTEGAIRLEGADVSRTPPNKRNVNTVFQHYALFPHMTVWDNVAY
MSMEG_3281|M.smegmatis_MC2_155 IAGFESPTEGAIRLEGVDVSRVPPHKRNVNTVFQHYALFPHMTVWDNVAY
Mb2419c|M.bovis_AF2122/97 IAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAF
Rv2397c|M.tuberculosis_H37Rv IAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAF
MMAR_3715|M.marinum_M IAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAY
MUL_3658|M.ulcerans_Agy99 IAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAY
MAV_1785|M.avium_104 IAGLDQPDTGTVTIYGRDVTRVPPQRRGIGFVFQHYAAFKHLTVRDNVAY
TH_2424|M.thermoresistible__bu IAGLDRPDTGTITINGRDVTDVPPQRRGIGFVFQHYAAFKHLTVRDNVAF
MAB_1655|M.abscessus_ATCC_1997 IAGLDNPDSGTITINGRDVTGVPPQRRDIGFVFQHYAAFKHLTVWENVAF
MLBr_01089|M.leprae_Br4923 IAGLEDISSGELRIDGDRVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAF
***:: * : : * *. .*: *.: *** ** : *:** :*:*:
Mflv_3138|M.gilvum_PYR-GCK GPRSKKLDKGEIRKRVDELLEIVRLSDFAERKPAQLSGGQQQRVALARAL
Mvan_3387|M.vanbaalenii_PYR-1 GPRSKKLGKGEIRKRVDELLDIVRLTDFAERKPAQLSGGQQQRVALARAL
MSMEG_3281|M.smegmatis_MC2_155 GPRSAKKDKAEIKRSVDELLEIVKLSDFAKRKPAQLSGGQQQRVALARAL
Mb2419c|M.bovis_AF2122/97 GLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARAL
Rv2397c|M.tuberculosis_H37Rv GLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQRMALARAL
MMAR_3715|M.marinum_M GLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPNQLSGGQRQRMALARAL
MUL_3658|M.ulcerans_Agy99 GLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPDQLSGGQRQRMALARAL
MAV_1785|M.avium_104 GLKVRKRPKAEIKAKVDNLLEVVGLSGFQGRYPNQLSGGQRQRMALARAL
TH_2424|M.thermoresistible__bu GLKIRRRPKREIAEKVDNLLEVVGLAGFQNRYPNQLSGGQRQRMALARAL
MAB_1655|M.abscessus_ATCC_1997 GLKIRKKPKAEIKKKVDDLLEVVGLSGFHTRYPAQLSGGQRQRMALARAL
MLBr_01089|M.leprae_Br4923 PLMLAKVKKAEIAQKVSETAQILDLTDLLDRKPSQLSGGQRQRVAMGRAI
: * ** *.: ::: *:.: * * ******:**:*:.**:
Mflv_3138|M.gilvum_PYR-GCK VNYPSALLLDEPLGALDLKLRHVMQFELKRIQREIGITFIYVTHDQEEAL
Mvan_3387|M.vanbaalenii_PYR-1 VNYPSALLLDEPLGALDLKLRHVMQFELKRIQREVGITFIYVTHDQEEAL
MSMEG_3281|M.smegmatis_MC2_155 VNYPSALLLDEPLGALDLKLRHAMQFELKRIQREVGITFIYVTHDQEEAL
Mb2419c|M.bovis_AF2122/97 AVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEAL
Rv2397c|M.tuberculosis_H37Rv AVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLVTHDQAEAL
MMAR_3715|M.marinum_M AVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEAL
MUL_3658|M.ulcerans_Agy99 AVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEAL
MAV_1785|M.avium_104 AVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEAL
TH_2424|M.thermoresistible__bu AVDPEVLLLDEPFGALDAKVREDLRTWLRRLHEEVHVTTVLVTHDQSEAL
MAB_1655|M.abscessus_ATCC_1997 AVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLVTHDQAEAL
MLBr_01089|M.leprae_Br4923 VRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQRRLGATTVYVTHDQTEAM
. *..:*:***:. ** *:* : : *:: .: * : ***** **:
Mflv_3138|M.gilvum_PYR-GCK TMSDRIAVMNAGNVEQIGTPTEIYDRPATVFVASFIG--QANLWAGRQTG
Mvan_3387|M.vanbaalenii_PYR-1 TMSDRIAVMNAGNVEQIGTPTEIYDRPATVFVASFIG--QANLWAGRQTG
MSMEG_3281|M.smegmatis_MC2_155 TMSDRIAVMNAGNVEQIGTPTEIYDKPATVFVANFIG--QANLWPGRQTE
Mb2419c|M.bovis_AF2122/97 DVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNG----
Rv2397c|M.tuberculosis_H37Rv DVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLG--AVSTLNG----
MMAR_3715|M.marinum_M DVADRIAVLNSGRIEQVGSPTEVYDAPANAFVMSFLG--AVSALNG----
MUL_3658|M.ulcerans_Agy99 DVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVMSFLG--AVSALNG----
MAV_1785|M.avium_104 DVADRIAVLNQGRIEQIGSPTEVYDAPTNAFVMSFLG--AVSTLNG----
TH_2424|M.thermoresistible__bu DVADRIAVLNNGRIEQVGSPAEVYDSPANEFVMSFLG--AVSSLNG----
MAB_1655|M.abscessus_ATCC_1997 DVADRIAVLNKGRIEQVGSPEDLYDRPANSFVMSFLG--PVAKLNG----
MLBr_01089|M.leprae_Br4923 TLGDRVVVMRSGVVQQIGTPDELYERPVNLFVAGFIGSPVMNFFPAKLTP
:.**:.*:. * ::*:*:* ::*: *.. ** .*:* .
Mflv_3138|M.gilvum_PYR-GCK RTNRDFVEIDVLGSTLKARPGETTIEPGGHATLMVRPERVRVSMDAPTGD
Mvan_3387|M.vanbaalenii_PYR-1 RANRDYVEVDVLGSTLKARPGETTIEPGGHATLMVRPERIRVSMDAPTGD
MSMEG_3281|M.smegmatis_MC2_155 RTAGDYVEVEVLGTKLRAKPGDTAIEAGGHATLMIRPERVRVSIDAPTGD
Mb2419c|M.bovis_AF2122/97 ---------------SLVRPHDIRVGR--------TPNMAVAAADGTAGS
Rv2397c|M.tuberculosis_H37Rv ---------------SLVRPHDIRVGR--------TPNMAVAAADGTAGS
MMAR_3715|M.marinum_M ---------------ALVRPHDIRVGR--------TPEMAVAAADGTGES
MUL_3658|M.ulcerans_Agy99 ---------------ALVRPHDIRVGR--------TPEMAVAAADGTGES
MAV_1785|M.avium_104 ---------------TLVRPHDIRVGR--------TPEMAVAAEDGTAES
TH_2424|M.thermoresistible__bu ---------------TLVRPHDIWVGR--------HPELPTS--DSTLQA
MAB_1655|M.abscessus_ATCC_1997 ---------------ILVRPHDIRVGR--------NADLARAAAEGTGET
MLBr_01089|M.leprae_Br4923 NG-----LTLPLGELNLSRDVQAMIGQHP------VPDRVIVGVRPEHLT
: : : .:
Mflv_3138|M.gilvum_PYR-GCK VAGVRATVSDLTFQGPVVRLSLAAPDD-STVIAHVGP-EQDLPLLRPGDE
Mvan_3387|M.vanbaalenii_PYR-1 VAAVRATVSDLTFQGPVVRLSLAAPDD-STVIAHVGP-EQDLPLLRPGDD
MSMEG_3281|M.smegmatis_MC2_155 VATVPATVTDLTFQGPVVRLSLAAPDD-STIVAHVGA-EQNLPLLRPGDR
Mb2419c|M.bovis_AF2122/97 TGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDT
Rv2397c|M.tuberculosis_H37Rv TGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDT
MMAR_3715|M.marinum_M TGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDT
MUL_3658|M.ulcerans_Agy99 TGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDT
MAV_1785|M.avium_104 TGVARAIVDRVVKLGFEVRVELTSAATGGPFTAQITRGDAEALALREGDT
TH_2424|M.thermoresistible__bu TGVVRARIDRVVMLGFEVRLELTSATNNAPFTAQITRGDAEALGLRSGDT
MAB_1655|M.abscessus_ATCC_1997 TGVTKATVDRVVYLGFEVRVELTSAATGEQFTAQITRGDAEALGLREGDP
MLBr_01089|M.leprae_Br4923 DAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCDVYSAQLDELA
. . *::.*. .
Mflv_3138|M.gilvum_PYR-GCK VYVSWAPDASLVLP--GADIPTTEDLEEMLDDS-----------------
Mvan_3387|M.vanbaalenii_PYR-1 VFVSWAPDASLVLP--GADIPTTEDLEEMLDDS-----------------
MSMEG_3281|M.smegmatis_MC2_155 VHVSWSPDASRVLP--AADIPTTEDLEDMLDDS-----------------
Mb2419c|M.bovis_AF2122/97 VYVRATRVPPIAG---GVSGVDDAGVERVKVTST----------------
Rv2397c|M.tuberculosis_H37Rv VYVRATRVPPIAG---GVSGVDDAGVERVKVTST----------------
MMAR_3715|M.marinum_M VYVRATRVPPIAG---AAPAVPDDGAGSTPSAAQIGVGGQ----------
MUL_3658|M.ulcerans_Agy99 VYVRATRVPPIAG---AAPAVPDDGAGSTPRAAQIGVGGQ----------
MAV_1785|M.avium_104 VYVRATRVPPITAGATTVPAVSRDGADEATLTSA----------------
TH_2424|M.thermoresistible__bu VYVRATRVP----------ALPTGDVDERVAAR-----------------
MAB_1655|M.abscessus_ATCC_1997 VYVRVTRVP---------------DVGELAEVAS----------------
MLBr_01089|M.leprae_Br4923 SELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGVNLTVSA
: .
Mflv_3138|M.gilvum_PYR-GCK ----
Mvan_3387|M.vanbaalenii_PYR-1 ----
MSMEG_3281|M.smegmatis_MC2_155 ----
Mb2419c|M.bovis_AF2122/97 ----
Rv2397c|M.tuberculosis_H37Rv ----
MMAR_3715|M.marinum_M ----
MUL_3658|M.ulcerans_Agy99 ----
MAV_1785|M.avium_104 ----
TH_2424|M.thermoresistible__bu ----
MAB_1655|M.abscessus_ATCC_1997 ----
MLBr_01089|M.leprae_Br4923 PTDA