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PEPATGAPRIVDLPRETLEAMRAGLPALVDRMVEAVIAEVPLLAQAAQESWRPVIDTSAQLLLGSLIDEL GTSTGPPTAVPMQEVLDIAHRFGRREARNGRPAEVQLAAYRVGARELWRDWSALAAQGGVDRDQVSAFAE MFFAYLDLISAAGVAGHAQEQSRSGLDRERRRERLVRMLLSDTASDELDLAAEYATWATPRTLTAVAMPT RQERGATAITSDPRTLRVPDDAVDSRIGMHVVLVCDVGGSARASFVASLAGTGAVVGPARSWTDAQSSVR RVLRAMRLRRPDGGDVLDTEEILPELVVGADADALADLRARALAPLADFPEASRDRLTETLRSWLLHQGR RDDIAADLFVSPSTIRYRLRQLRDAYGDRLRDPRTIAELTVALAMDVATLGGQTRPAIVGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0936 | - | - | 100% (412) | hypothetical protein Mflv_0936 |
| M. gilvum PYR-GCK | Mflv_2780 | - | 3e-11 | 25.69% (288) | hypothetical protein Mflv_2780 |
| M. gilvum PYR-GCK | Mflv_0801 | - | 1e-05 | 27.91% (258) | transcriptional regulator, CdaR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2266 | - | 3e-10 | 26.86% (283) | hypothetical protein Mb2266 |
| M. tuberculosis H37Rv | Rv2242 | - | 3e-10 | 26.86% (283) | hypothetical protein Rv2242 |
| M. leprae Br4923 | MLBr_01652 | - | 8e-09 | 26.15% (283) | hypothetical protein MLBr_01652 |
| M. abscessus ATCC 19977 | MAB_0762 | - | 7e-13 | 24.69% (324) | hypothetical protein MAB_0762 |
| M. marinum M | MMAR_3335 | - | 2e-08 | 36.94% (111) | hypothetical protein MMAR_3335 |
| M. avium 104 | MAV_4933 | - | 2e-12 | 25.00% (364) | hypothetical protein MAV_4933 |
| M. smegmatis MC2 155 | MSMEG_4324 | - | 3e-14 | 28.57% (273) | hypothetical protein MSMEG_4324 |
| M. thermoresistible (build 8) | TH_1338 | - | 4e-11 | 25.98% (281) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1307 | - | 1e-08 | 36.94% (111) | hypothetical protein MUL_1307 |
| M. vanbaalenii PYR-1 | Mvan_3753 | - | 2e-11 | 28.83% (274) | hypothetical protein Mvan_3753 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4324|M.smegmatis_MC2_155 -------MPDNRFVPPK------STVEVLEAVPDSLLRRLKQYSGRLATE
Mvan_3753|M.vanbaalenii_PYR-1 -------MTDNRFIPPR------STVEVLENVPESTLRRLKQYSGRLATQ
TH_1338|M.thermoresistible__bu -------VPDNRFVPPQ------STLEVLESVPESVLRRLKQYSGRLATE
Mb2266|M.bovis_AF2122/97 -------MNDNQLAPVAR---PRSPLELLDTVPDSLLRRLKQYSGRLATE
Rv2242|M.tuberculosis_H37Rv -------MNDNQLAPVAR---PRSPLELLDTVPDSLLRRLKQYSGRLATE
MMAR_3335|M.marinum_M -------MNDNQFSAIARLGSARSPLELLETVPDSLLRRLKQYSGRLATE
MUL_1307|M.ulcerans_Agy99 -------MNNNQFSAIARLGSARSPLELLETVPDSLLRRLKQYSGRLATE
MLBr_01652|M.leprae_Br4923 -------MNHNHFVPAP---PRRLPLELLDTVPDSLLRRLKQYSGRLATE
Mflv_0936|M.gilvum_PYR-GCK -------MPEPATGAPRIVDLPRETLEAMRAGLPALVDRMVEAV--IAEV
MAB_0762|M.abscessus_ATCC_1997 -----------------------------------MGEQLLARVDELCAE
MAV_4933|M.avium_104 MKDFRAPVNGVDGDSASALVAVPKSQGAQTIRPDSVSRLVGALLDDHAAV
: .
MSMEG_4324|M.smegmatis_MC2_155 AVHAMEQRLPFFAELDASQRASVQLVVQTAVVNFVEWMRNPESNVGYTAQ
Mvan_3753|M.vanbaalenii_PYR-1 AVHAMEERLPFFAELDASQRASVQLVVQTAVVNFAEWMRDPRSNVSYTAQ
TH_1338|M.thermoresistible__bu AVHTMEERLPFFADLEASQRASVHLVVQTAVVNFVEWMRDPRSNVTYTMQ
Mb2266|M.bovis_AF2122/97 AVSAMQERLPFFADLEASQRASVALVVQTAVVNFVEWMHDPHSDVGYTAQ
Rv2242|M.tuberculosis_H37Rv AVSAMQERLPFFADLEASQRASVALVVQTAVVNFVEWMHDPHSDVGYTAQ
MMAR_3335|M.marinum_M AVSAMQERLPFFADLEASQRASVALVVQTAVVNFAEWMQNPRSDVSYTAQ
MUL_1307|M.ulcerans_Agy99 AVSAMQERLPFFADLEASQRASVALVVQTAVVNFAEWMQNPRSDVSYTAQ
MLBr_01652|M.leprae_Br4923 AVTAMQERLPFFADLEASQRASVTLVVQTAVVNFVQWMQNPHSDVSYTAQ
Mflv_0936|M.gilvum_PYR-GCK PLLAQAAQESWRPVIDTSAQLLLGSLIDELGTSTGPPTAVPMQEVLDIAH
MAB_0762|M.abscessus_ATCC_1997 QCRIIRERVAAYRDPVLVTDEDLFAAGRDQMVYVLAAMGSGAPDTS-AAA
MAV_4933|M.avium_104 VGRVRSVIRSRLPVYRSVADEALEAELEWVLRSAVGGREALHEPQIAGLA
. :
MSMEG_4324|M.smegmatis_MC2_155 AFEVVPQDLRRRVALRQSVEMVRTSMEFFEEAVPLLAR---SEEQLTALT
Mvan_3753|M.vanbaalenii_PYR-1 AFEVVPQDLRRRIALRQSVEMVRVTMEFFEEVVPLLAR---SEDQLAAMT
TH_1338|M.thermoresistible__bu AFEVVPQDLTRRIALRQTVEMVRTTMEFFEQVVPLLAR---SEEQVTALT
Mb2266|M.bovis_AF2122/97 AFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLAR---SEEQLTALT
Rv2242|M.tuberculosis_H37Rv AFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLAR---SEEQLTALT
MMAR_3335|M.marinum_M AFELVPQDLTRRIALRHTVDMVRVTMEFFEEVVPLLAR---SEEQLTALT
MUL_1307|M.ulcerans_Agy99 AFELVPQDLTRRIALRHTVDMVRVTMEFFEEVVPLLAR---SEEQLTALT
MLBr_01652|M.leprae_Br4923 AFELVPQDLARRIALRHTVDMVRVTMEFFEEVVPLLAR---SEEQLTALT
Mflv_0936|M.gilvum_PYR-GCK RFGRREARNGRPAEVQLAAYRVG-ARELWRDWSALAAQGGVDRDQVSAFA
MAB_0762|M.abscessus_ATCC_1997 RVGRLRAEQGVPLADVMSAYRAG-GQFLWDALSQAIDAAGLSRQELRAAA
MAV_4933|M.avium_104 AIGEARARDGVPVDDMLRAWRIG-VEVVVECAREAARRLGVDDARVLELV
. . . . .: .
MSMEG_4324|M.smegmatis_MC2_155 AGILRYSRDLAFAAASAYADQAEARGAWDIRMEANIVDAVVRGDTGPELQ
Mvan_3753|M.vanbaalenii_PYR-1 AGILRYSRDLAFAAATAYADQAEARGAWDTRMEANLVDAVVRGGTRPELQ
TH_1338|M.thermoresistible__bu AGILRYSRDLAFAAATAYADAAEARGAWDTRMEANVVDAVVRGAVGPELQ
Mb2266|M.bovis_AF2122/97 VGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELL
Rv2242|M.tuberculosis_H37Rv VGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELL
MMAR_3335|M.marinum_M VGILKYSRDLAFTAASAYADAAEARGTWDSRMEASVVDAVVRGDTGPELL
MUL_1307|M.ulcerans_Agy99 VGILKYSRDLAFTAASAYADAAEARGTWDSRMEASVVDAVVRGDTGPELL
MLBr_01652|M.leprae_Br4923 VGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELL
Mflv_0936|M.gilvum_PYR-GCK EMFFAYLDLISAAGVAGHAQEQSRSGLDRERRRERLVRMLLSDTASDELD
MAB_0762|M.abscessus_ATCC_1997 SQAWQNHDRYTDAMAEGYRDVVVEQLIQRDQERAALVSGLIDGRFPAGIT
MAV_4933|M.avium_104 QSALAWSDIAMATSAKAHRRTERALALEAEESDAEFVRGALMGSLPAAEL
: . .: . .* : .
MSMEG_4324|M.smegmatis_MC2_155 SQAAALNWDATAPATVIVGLPRADR--------IEMARDDVHAVVRRNDR
Mvan_3753|M.vanbaalenii_PYR-1 SQAAALNWDATAPATVIVGMPRPDR--------AEFAGDDVHEVADRNGR
TH_1338|M.thermoresistible__bu SQAAALNWDATAPATVVVGLPRPDR--------LEVVSQDVHHVANRHGR
Mb2266|M.bovis_AF2122/97 SRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGR
Rv2242|M.tuberculosis_H37Rv SRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGR
MMAR_3335|M.marinum_M SRAAALNWDTTAPATVVVGTPASARDGSDG---SERAIQDVRDAAAQHGR
MUL_1307|M.ulcerans_Agy99 SRAAALNWDTTAPATVVVGTPASARDGSDG---SERAIQDVRDAAAQHGR
MLBr_01652|M.leprae_Br4923 SRAAALNWDTTAPATVVVGTPTPNHDGPNGQVSSERASQEVREIAARHGR
Mflv_0936|M.gilvum_PYR-GCK LAAEYATWATPRTLTAVAMPTRQER---------GATAITSDPRTLRVPD
MAB_0762|M.abscessus_ATCC_1997 AWNAAHQLGLPESGAFVVVAIESGP----------LDYRTLRSAEKALRD
MAV_4933|M.avium_104 RMHAELRGLDPGAEYVAVRARLGGD------------GPHLRLEQSLGFQ
. . .
MSMEG_4324|M.smegmatis_MC2_155 AALSDVHGTWLVTIVSGPLSATDRFLADLMSVFADGPVVIGPTTPTLTAA
Mvan_3753|M.vanbaalenii_PYR-1 TALSDVHGTWLVAIISGGLSPTDRFLSELMTVFADGPVVIGPTAPTLGAA
TH_1338|M.thermoresistible__bu TALSDVHGTWLVTIVSGALSPTDRFLTDLLDVFADGPVVLGPTAPTLSAA
Mb2266|M.bovis_AF2122/97 AALTDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAA
Rv2242|M.tuberculosis_H37Rv AALTDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAA
MMAR_3335|M.marinum_M AALTDVHGTWLVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAA
MUL_1307|M.ulcerans_Agy99 AALTDVHGTWLVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAA
MLBr_01652|M.leprae_Br4923 AALTDVHGTWLVAIISGQLAPTDKFFSDLLHAFSDGPVVIGPTAPMLTAA
Mflv_0936|M.gilvum_PYR-GCK DAVDSRIGMHVVLVCDVGGSARASFVASLAGTG----AVVGP-ARSWTDA
MAB_0762|M.abscessus_ATCC_1997 QGFASAWRVDPDMQVGIVALPTPSRLEELGETLRNLGVRRIGVSPVYDGY
MAV_4933|M.avium_104 DPAHSRRGLCALLDGDLAG--------FLIEPPRDVEGVVGFGPPRPLTR
. . * .
MSMEG_4324|M.smegmatis_MC2_155 HRSATEAISGMNAVAGWPSAPRPVSARELLPERALLGDADAVTALETEVM
Mvan_3753|M.vanbaalenii_PYR-1 HRSATEAIAGMNAVAGWAGAPRPVSARELLPERALLGDATAGAALEAEVM
TH_1338|M.thermoresistible__bu YRSATEAIAGMNAVAGWSGAPRPVPARELLPERALLGDQTAIAALESEVM
Mb2266|M.bovis_AF2122/97 HRSASEAISGMNAVAGWRGAPRPVLARELLPERALMGDASAIVALHTDVM
Rv2242|M.tuberculosis_H37Rv HRSASEAISGMNAVAGWRGAPRPVLARELLPERALMGDASAIVALHTDVM
MMAR_3335|M.marinum_M YHSASEAISGMNAVAGWRGAPRPVLARELLPERALMGDASAIVALHTDVM
MUL_1307|M.ulcerans_Agy99 YHSASEAISGMNAVAGWRGASRPVLARELLPERALMGDASAIVALHTDVM
MLBr_01652|M.leprae_Br4923 YHSASEAVSGMNAVAGWSGAPRPVQARELLPERALMGDASAIVALHTDVM
Mflv_0936|M.gilvum_PYR-GCK QSSVRRVLRAMRLRR--PDGGDVLDTEEILPELVVGADADALADLRARAL
MAB_0762|M.abscessus_ATCC_1997 PPPGPPLNYAKAALLAATEDDPVVAFDANPYAVAAITDPQTMARYRDLVL
MAV_4933|M.avium_104 LSESYRMAARALVTAEACGLRGAYDIAALGLRTAVAIDADVGELLRKRYL
. * . . :
MSMEG_4324|M.smegmatis_MC2_155 RPLADAGPA----LTETLDAFLDSGGAIEACARKLFVHPNTVRYRLRRIA
Mvan_3753|M.vanbaalenii_PYR-1 RPLSDAGPA----LMETLDAYLDSGGAIEACARKLFVHPNTVRYRLKRIA
TH_1338|M.thermoresistible__bu RPLADAGPT----LTETLDAFLESGGAIEACARRLFVHPNTVRYRLRRIA
Mb2266|M.bovis_AF2122/97 RPLADAGPT----LIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRIT
Rv2242|M.tuberculosis_H37Rv RPLADAGPT----LIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRIT
MMAR_3335|M.marinum_M RPLADAGPT----LIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRIT
MUL_1307|M.ulcerans_Agy99 RPLADAGPT----LIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRIT
MLBr_01652|M.leprae_Br4923 LPLADAGPT----LIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRIT
Mflv_0936|M.gilvum_PYR-GCK APLADFPEASRDRLTETLRSWLLHQGRRDDIAADLFVSPSTIRYRLRQLR
MAB_0762|M.abscessus_ATCC_1997 GSLTEIGVVDRQLLVDTFRQWVDCDGSIPATARVLFCHPNTVRYRLRRLK
MAV_4933|M.avium_104 EPLSVGGSSRE--LIATVRTYLACGMHVERTATRLFVHQNTVRYRLARFE
.*: * *. :: * ** .*:**** ::
MSMEG_4324|M.smegmatis_MC2_155 DFTGRDPAVPRDAYVLRVASTVGRLSKHAYRASTINSAVSVVPTIRPATS
Mvan_3753|M.vanbaalenii_PYR-1 DFTGRDPTVPRDAYVLRVASSVGRLARQAHLSAAPAAASAQAIGVASVTS
TH_1338|M.thermoresistible__bu EITGRDPAVPRDAYVLRVAVSVSRLTRQSYQSSTVNPDLGSTAGWRGQAA
Mb2266|M.bovis_AF2122/97 DFTGRDPTQPRDAYVLRVAATVGQLNYPTPH-------------------
Rv2242|M.tuberculosis_H37Rv DFTGRDPTQPRDAYVLRVAATVGQLNYPTPH-------------------
MMAR_3335|M.marinum_M DFTGRDPTQPRDAYVLRVAATVGQLNYPTPPSGAANNTITPVPLPVRRGT
MUL_1307|M.ulcerans_Agy99 DFTGRDPTQPRDAYVLRVAATVGQLNYPTPPSGAANNTITPVPLPVRRGT
MLBr_01652|M.leprae_Br4923 DFTGHDPTLPRDAYVLRVAATVGKLNYPTHH-------------------
Mflv_0936|M.gilvum_PYR-GCK DAYGDRLRDPRTIAELTVALAMDVATLGGQTRPAIVGG------------
MAB_0762|M.abscessus_ATCC_1997 QLTGRDVARPRDIAELHLAVEADRRLSWA---------------------
MAV_4933|M.avium_104 ELTGASLRDTEVVTEVWWVLELAAMRL-----------------------
: * .. : .
MSMEG_4324|M.smegmatis_MC2_155 AGSRGT
Mvan_3753|M.vanbaalenii_PYR-1 PENLGT
TH_1338|M.thermoresistible__bu GGHRAM
Mb2266|M.bovis_AF2122/97 ------
Rv2242|M.tuberculosis_H37Rv ------
MMAR_3335|M.marinum_M EGP---
MUL_1307|M.ulcerans_Agy99 EGP---
MLBr_01652|M.leprae_Br4923 ------
Mflv_0936|M.gilvum_PYR-GCK ------
MAB_0762|M.abscessus_ATCC_1997 ------
MAV_4933|M.avium_104 ------