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SRRVIQFSTGNVGIHALRTIIGRPDLELVGLHAASPDKVGRDAADICGIPGATGVVATSDIDELVALQAD CVVYTSQAETRPHEAMADLIRFLSAGTNVVGTSFVWLVAPEFTDEWLREPLLRACRDGNSTLYINGIDPG FSGDTLVYSALSLAGRATAITVQEICEYGSYDDAEFTGVTFGFGTEPEHEPILFAPGILASMWGIQVRSL ARDLGVTLDEVRERHEKWVTPKPISTTMMDVAPGRVAAVRFGVEGVRDGEVVITMEHVNRLTAADAPEWA YPPDGRPGVHRVTVEGDPGIRIDTHVGGSGVDHNIGGVVATAARAVNAIEAVCRAPAGILAAHDLRPLDH LPGTMW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0926 | - | - | 100% (357) | hypothetical protein Mflv_0926 |
| M. gilvum PYR-GCK | Mflv_1777 | - | e-119 | 58.15% (356) | dihydrodipicolinate reductase |
| M. gilvum PYR-GCK | Mflv_1824 | - | 2e-68 | 40.06% (347) | dihydrodipicolinate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0949c | - | 1e-65 | 39.65% (343) | hypothetical protein Mb0949c |
| M. tuberculosis H37Rv | Rv0926c | - | 1e-65 | 39.65% (343) | hypothetical protein Rv0926c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4633 | - | 6e-66 | 39.83% (344) | hypothetical protein MAB_4633 |
| M. marinum M | MMAR_4582 | - | 2e-65 | 39.65% (343) | hypothetical protein MMAR_4582 |
| M. avium 104 | MAV_2461 | - | 1e-135 | 64.33% (356) | hypothetical protein MAV_2461 |
| M. smegmatis MC2 155 | MSMEG_5586 | - | 2e-68 | 40.70% (344) | hypothetical protein MSMEG_5586 |
| M. thermoresistible (build 8) | TH_4586 | - | 1e-123 | 58.87% (355) | PUTATIVE dihydrodipicolinate reductase |
| M. ulcerans Agy99 | MUL_4353 | - | 4e-31 | 31.93% (357) | hypothetical protein MUL_4353 |
| M. vanbaalenii PYR-1 | Mvan_4970 | - | 1e-124 | 59.83% (356) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0949c|M.bovis_AF2122/97 ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
Rv0926c|M.tuberculosis_H37Rv ----MAIPVVQLGTGNVGVHSLRALIADPEFELTGVWVSSDAKAGKDAAE
MMAR_4582|M.marinum_M ----MAIPVVQLGTGNVGLHSLRALITNPEFELTGVWVSSDAKAGKDAAE
MSMEG_5586|M.smegmatis_MC2_155 ----MAIRVAAIGTGNVGRHALRQLITNPAYELTAVWVSSPEKAGKDAGD
MAB_4633|M.abscessus_ATCC_1997 ---MTKTRVAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGA
TH_4586|M.thermoresistible__bu -----MRRVVQFSTGNVGRHSLRTLIGRPDLELVGVHAAGPEKIGRDAAE
Mvan_4970|M.vanbaalenii_PYR-1 -----MRRVVQFSTGNVGRHSLAALIGRPDLELVGVHAASADKIGRDAAE
MAV_2461|M.avium_104 -----MRRVIQFSTGNVGRHSLRAIIGRPDLELVGVHAAGPEKIGRDAAQ
Mflv_0926|M.gilvum_PYR-GCK ----MSRRVIQFSTGNVGIHALRTIIGRPDLELVGLHAASPDKVGRDAAD
MUL_4353|M.ulcerans_Agy99 MSGPAKLRVIQWATGGVGKAAIECILNHPQLELAGCWVHSAAKHGLDVGT
* .**.** :: :: * **.. . . * * *..
Mb0949c|M.bovis_AF2122/97 LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
Rv0926c|M.tuberculosis_H37Rv LAGLADSTGVRASTDLNAVLATGPRCAVYNAMADNRLPEALEDYRRILAA
MMAR_4582|M.marinum_M LAGFAESTGVKASTDLDAVLASGPQCAVYNAMADNRLPEALDDYRRVLAA
MSMEG_5586|M.smegmatis_MC2_155 LAGLEVTTGIKATDSLDEVLATEPECAVYTAMADNRLPDALEDYRRILAA
MAB_4633|M.abscessus_ATCC_1997 LAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSA
TH_4586|M.thermoresistible__bu LCGLSEPTGVIATGDLDALLALQPDCVVYTALGETRPAEAIEQMTKILSA
Mvan_4970|M.vanbaalenii_PYR-1 LCGLSDPTGVLATDDLDALIALKPDCVVYTALGETRPMEAIEQMSRLLAA
MAV_2461|M.avium_104 LCGLDEPTGIIATDDIDALVALNADCVVYTSQGETRPMEAIEQMSRFLAA
Mflv_0926|M.gilvum_PYR-GCK ICGIPGATGVVATSDIDELVALQADCVVYTSQAETRPHEAMADLIRFLSA
MUL_4353|M.ulcerans_Agy99 IIGAAR-FGVTATNDVDELLALDADCVMYSPQVAD-----EQDVKAILRS
: * *: *: . ::* . *.:*.. : .* :
Mb0949c|M.bovis_AF2122/97 GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
Rv0926c|M.tuberculosis_H37Rv GINIVGSGPVFLQYPWQVIPDEIIKPLQDAARAGNSSLYVNGIDPGFAND
MMAR_4582|M.marinum_M GVNIVGSGPVFLQYPWQVLPDELVKPLEDAAREGNSSLYVSGIDPGFAND
MSMEG_5586|M.smegmatis_MC2_155 GVNVVGSSAVFLQYPWQVLPEELVKPIEDAAHAGGASLFVNGIDPGFAND
MAB_4633|M.abscessus_ATCC_1997 GINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFAGGIDPGFAND
TH_4586|M.thermoresistible__bu GVNVVGTSLVWLATP-RQADEWLRAPLEQACKAGNSSLFVSGIDPGYSAD
Mvan_4970|M.vanbaalenii_PYR-1 GINVVGTSMVWLVTP-RHADGWLREPLEQACATGNSSLYVNGIDPGYSGD
MAV_2461|M.avium_104 GTNVVGTSMVWLVAP-RHAEEWLREPLQRACEAGNTSLYVNGIDPGFSGD
Mflv_0926|M.gilvum_PYR-GCK GTNVVGTSFVWLVAP-EFTDEWLREPLLRACRDGNSTLYINGIDPGFSGD
MUL_4353|M.ulcerans_Agy99 GKNVFTP--VGWVYP--DLSKPRVKAVADAAVAGGVTLHGSGIHPGGITE
* *: . * * .: *. *. ::. .**.** :
Mb0949c|M.bovis_AF2122/97 LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFG-KPMDQIPML
Rv0926c|M.tuberculosis_H37Rv LLPMALAGTCESIEQIRCMEIVDYATYDSAVVMFDVMGFG-KPMDQIPML
MMAR_4582|M.marinum_M LLPMALAGTCQSIEQIRCMEIVDYATYDSAVVMFDVMGFG-KPLDEIPML
MSMEG_5586|M.smegmatis_MC2_155 LLPLALAGTCQQIEQIRCMEIVDYATYDSATVMLDVMGFG-KSLDETPML
MAB_4633|M.abscessus_ATCC_1997 LLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFG-KPMEETPML
TH_4586|M.thermoresistible__bu TAVHSALSLVTRARSVTVQEIFDYANYDDWEFTGTTMGFGSAPDDE-PML
Mvan_4970|M.vanbaalenii_PYR-1 TAVHAALSLVTRASSVTVQEIFDYGNYDDYEYTGTAMGFGNSPQDELPMA
MAV_2461|M.avium_104 TLVHAAVSLATRVSSITVQEIFDYGNYDDAEFTGAAMGFGTAPDDDSPMM
Mflv_0926|M.gilvum_PYR-GCK TLVYSALSLAGRATAITVQEICEYGSYDDAEFTGVTFGFGTEPEHE-PIL
MUL_4353|M.ulcerans_Agy99 RFPLMVSSLSSAITHVRAEEFSDIRTYNAPDVVRDIMGFG-VPHAQAMQG
. : *: : .*: :*** . :
Mb0949c|M.bovis_AF2122/97 LQPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGHIP
Rv0926c|M.tuberculosis_H37Rv LQPGVLSLAWGSVVRQLAAGLGISLD-GVEEMYVREPAPEAFNIASGHIP
MMAR_4582|M.marinum_M LQPGVLSLAWGSVVRQLAAGLGLSLD-VVEEMYVREPAPHAFDIASGHIP
MSMEG_5586|M.smegmatis_MC2_155 LQPGVLSLAWGSVVRQLAAGLGIELD-AVTEEHTRVPAPEDFDIAAGHIS
MAB_4633|M.abscessus_ATCC_1997 LQPGVLSLAWGSVVRQLAAGLGVELD-EVTEVYEKLSAPEDFDISSGHIP
TH_4586|M.thermoresistible__bu LMPGVITAMFGGLVRNLADQLGVELD-DVRQRTERWFTTERIECRLTTVE
Mvan_4970|M.vanbaalenii_PYR-1 FQPGVVASLFGGLVRSLAAHLDVELD-EVRERCEPWYTDQRIECTMTTVE
MAV_2461|M.avium_104 FLPGVIVAMWGGQVRSLADHLGVELD-DVRQRIERWFTPERIDCTMMTVQ
Mflv_0926|M.gilvum_PYR-GCK FAPGILASMWGIQVRSLARDLGVTLD-EVRERHEKWVTPKPISTTMMDVA
MUL_4353|M.ulcerans_Agy99 PMAALLESGFKMSVRMIANHMGFHIDPMIRATHEIAVATSDIASDVLPIA
..:: : ** :* :.. :* : : : :
Mb0949c|M.bovis_AF2122/97 KGSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQPAQ-PGGSYR
Rv0926c|M.tuberculosis_H37Rv KGSAAALRFEVLGLVDGVPAVVLEHVTRL-RADLCPEWPQPAQ-PGGSYR
MMAR_4582|M.marinum_M QGSAAALRFEVLGLVDGAPVVVLEHVTRL-REDLCPDWPQPAQ-PGGSYR
MSMEG_5586|M.smegmatis_MC2_155 EGTTAAMRFEVRGMVDGKPAVVLEHVTRL-RDDLCPEWPQPAQ-EGGSYR
MAB_4633|M.abscessus_ATCC_1997 AGTMAALHFEVRGIKDGRAVTVLEHFTRL-REDLAPNWPQPAH-EGGTYR
TH_4586|M.thermoresistible__bu PGGMAAVRFAVEGMRDDEPVITVEHVTRL-TPAAAPDWEFPPDNQPGVHR
Mvan_4970|M.vanbaalenii_PYR-1 PGRMAAVRFAAEGMRGGEPVITVEHINRL-TSAAAPQWEFPPEGHLGVHK
MAV_2461|M.avium_104 PGRMAAVRFATEGVRDGEPVITLEHVTRL-TRAAAPDWEYPPDGHTGVHR
Mflv_0926|M.gilvum_PYR-GCK PGRVAAVRFGVEGVRDGEVVITMEHVNRL-TAADAPEWAYPPDGRPGVHR
MUL_4353|M.ulcerans_Agy99 ADTVAGRKFRWQTLADGKPVITAAVNWLMGQADMHPDWSFGER--GERFE
. *. :* : .. . . : *:* ..
Mb0949c|M.bovis_AF2122/97 IEISGEPCYAMDICLSSRHGDHN----HAGLVATAMRIVNAIPAVVAAEP
Rv0926c|M.tuberculosis_H37Rv IEISGEPCYAMDICLSSRHGDHN----HAGLVATAMRIVNAIPAVVAAEP
MMAR_4582|M.marinum_M IEITGEPSYAMDLCLSSRRGDHN----HAGLVATAMRVVNAIPAVVAAPP
MSMEG_5586|M.smegmatis_MC2_155 VEVTGEPSYALDLCLSSPYGDHN----HAGLVATAARVVNAIPAVFAAPP
MAB_4633|M.abscessus_ATCC_1997 VEITGEPSYLLDLGSFSARGDHN----YANLIATAMRVVNAVPAVVAAEA
TH_4586|M.thermoresistible__bu VVVEGEPRIELNTHVSQPFFDVT----EAGCIATAARVINAIDWVCDAPP
Mvan_4970|M.vanbaalenii_PYR-1 VIVEGEPRVEVSTHLSHPVLDVT----DAGCVSTAARAVNAIDWVCRAPA
MAV_2461|M.avium_104 VVVAGEPRVEINTHVSHPLFDST----DAGCISTAARVVNAIDWVCRAPQ
Mflv_0926|M.gilvum_PYR-GCK VTVEGDPGIRIDTHVGGSGVDHN----IGGVVATAARAVNAIEAVCRAPA
MUL_4353|M.ulcerans_Agy99 IEITGNPSVSLVFKGLQPTSITEGLQRNPGVVATANHCANAIPVVCAADP
: : *:* : . ::** : **: * *
Mb0949c|M.bovis_AF2122/97 GIRTTLDLPLITGEGRYAAA----
Rv0926c|M.tuberculosis_H37Rv GIRTTLDLPLITGEGRYAAA----
MMAR_4582|M.marinum_M GIRTTLELPLVTGKGLYLPPAGAA
MSMEG_5586|M.smegmatis_MC2_155 GIRTTLDMPLITGKGLYAAR----
MAB_4633|M.abscessus_ATCC_1997 GIRTTLDLPLITGKGRAV------
TH_4586|M.thermoresistible__bu GLVEAADIPPTSLIRGLMW-----
Mvan_4970|M.vanbaalenii_PYR-1 GLVALENIPPTEMIRGLMW-----
MAV_2461|M.avium_104 GLIGVEDIPLAATMRGVLWQDR--
Mflv_0926|M.gilvum_PYR-GCK GILAAHDLRPLDHLPGTMW-----
MUL_4353|M.ulcerans_Agy99 GIATYLDLPLFAGRPARASRGLER
*: ::