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VAQLYDFFGEVFQRYFRPAMDAYPPRGGGPVERMFGLTDAVRDPLEQSRRAALAWGHAEVDNARFATELF VITQHGLIYAAELNNPRRSLYYLATPPSLFDPFVDQVERARLREGGAVVVDNRLGRDLAAAHPMDAALRR ILDQHWALRVDLSSPALC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0499 | - | - | 100% (159) | hypothetical protein Mflv_0499 |
| M. gilvum PYR-GCK | Mflv_0266 | - | 8e-07 | 31.43% (70) | glucose-6-phosphate 1-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1152 | zwf1 | 1e-10 | 31.90% (116) | glucose-6-phosphate 1-dehydrogenase |
| M. tuberculosis H37Rv | Rv1121 | zwf1 | 1e-10 | 31.90% (116) | glucose-6-phosphate 1-dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4339 | zwf1 | 2e-10 | 38.89% (72) | glucose-6-phosphate 1-dehydrogenase Zwf1 |
| M. avium 104 | MAV_1252 | zwf | 4e-11 | 41.46% (82) | glucose-6-phosphate 1-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5582 | - | 1e-41 | 53.33% (150) | hypothetical protein MSMEG_5582 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5904 | - | 8e-77 | 84.91% (159) | hypothetical protein Mvan_5904 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1152|M.bovis_AF2122/97 MVDGGGGASDLLVIFGITGDLARKMTFRALYRLERHQLLDCPILGVASDD
Rv1121|M.tuberculosis_H37Rv MVDGGGGASDLLVIFGITGDLARKMTFRALYRLERHQLLDCPILGVASDD
MMAR_4339|M.marinum_M MANGGGQASDLLVIFGITGDLARKMTFRALYRLERRGLLDCPIVGVASDD
MAV_1252|M.avium_104 MADDDSHPSDLLVIFGITGDLARKMTFRALYRLERREELEHPIIGVASDD
Mflv_0499|M.gilvum_PYR-GCK ---------MVAQLYDFFGEVFQRYFRPAMDAYPPRG--GGPVERMFGLT
Mvan_5904|M.vanbaalenii_PYR-1 ---------MVAQLYDFFGEVFQRYFRPAVDAYPPLG--GRPVEKIFTLT
MSMEG_5582|M.smegmatis_MC2_155 ---------MNDQVYDYFGSMFQRYFRPAVDEYPQTG--GVLVHRLMTST
::. *.: :: *: : :
Mb1152|M.bovis_AF2122/97 MSVGQLVKWARESI-GRTEKIDDAVFDRLAGRLSYLHGDVTDSQLYDSLA
Rv1121|M.tuberculosis_H37Rv MSVGQLVKWARESI-GRTEKIDDAVFDRLAGRLSYLHGDVTDSQLYDSLA
MMAR_4339|M.marinum_M MSVEQLVDRAREVIQGSSEPFDEAVFERFASRWSYLPGDVTDPALYTALA
MAV_1252|M.avium_104 ITLDQLLDRAREAIKATGETFDDAVFDRLAGRLSYLSGDVTDTGLYSELA
Mflv_0499|M.gilvum_PYR-GCK DAVRDPLEQSRRAALAWGH--AEVDNARFATELFVIT------QHGLIYA
Mvan_5904|M.vanbaalenii_PYR-1 DAVQDPLEQSRRAALVWGH--TEMGDAGFATELFVIT------QQGLVYA
MSMEG_5582|M.smegmatis_MC2_155 DEVQDRVAEARHAAYAWSK--VDLGTVDIASEFFMIT------QCGLMYG
: : : :*. . : :* . : .
Mb1152|M.bovis_AF2122/97 ELIGSACRPLYYLEMPPALFAPIVENLANVRLLERARVAVEKPFGHDLAS
Rv1121|M.tuberculosis_H37Rv ELIGSACRPLYYLEMPPALFAPIVENLANVRLLERARVAVEKPFGHDLAS
MMAR_4339|M.marinum_M KQIGHDRHGLYYLEMPPALFAPIVENLAKADLLRGARVAVEKPFGHDLDS
MAV_1252|M.avium_104 EKIGGDSRPLYYLEMPPSLFAPIVENLAKADLLERARVAVEKPFGHDLES
Mflv_0499|M.gilvum_PYR-GCK AELNNPRRSLYYLATPPSLFDPFVDQVERARLREGGAVVVDNRLGRDLAA
Mvan_5904|M.vanbaalenii_PYR-1 AELNNPRRSLYYLATPPSLFDPFVDQVERAELRQGAVVVVDNRFGRELAT
MSMEG_5582|M.smegmatis_MC2_155 ARFAHPDHPHYYLATPAALFDAFVDQVECCDVHAGDVIGVDRRCSRDLSA
: : *** *.:** .:*::: : : *:. .::* :
Mb1152|M.bovis_AF2122/97 ALELNARLRAVLGEDQILRVDHFLGKQPVVELEYLRFANQALAELWDRNS
Rv1121|M.tuberculosis_H37Rv ALELNARLRAVLGEDQILRVDHFLGKQPVVELEYLRFANQALAELWDRNS
MMAR_4339|M.marinum_M ARELNSRLRAVLNEDQILRVDHFLGKQPVVELQYLRFANRGLAELWDRKS
MAV_1252|M.avium_104 ARDLNARLRAVLDEDQILRVDHFLGKQPVEELQYLRFANNALAKLWDRDS
Mflv_0499|M.gilvum_PYR-GCK AHPMDAALRRILDQHWALRVDLSSPALC----------------------
Mvan_5904|M.vanbaalenii_PYR-1 ARPMDAALRRILDEHWALRVDLSSPALC----------------------
MSMEG_5582|M.smegmatis_MC2_155 AHPMDAALRRILDEHETLRVNVG---------------------------
* ::: ** :*.:. ***:
Mb1152|M.bovis_AF2122/97 ISEIHITMAEDFGVEDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGS
Rv1121|M.tuberculosis_H37Rv ISEIHITMAEDFGVEDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGS
MMAR_4339|M.marinum_M VSEIHVTMAENFGVEDRGKFYDAVGALRDVVQNHLLQVLALVAMEPPVGP
MAV_1252|M.avium_104 ISEIHITMAEDFGIEDRGKFYDAVGAVRDVVQNHLLQVLALVAMEPPVGA
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 SADDLNDKKAEVFRAMAPLDPDRCVRGQYLGYTEVAGVASDSATETYVAL
Rv1121|M.tuberculosis_H37Rv SADDLNDKKAEVFRAMAPLDPDRCVRGQYLGYTEVAGVASDSATETYVAL
MMAR_4339|M.marinum_M GADDLNDKKAEVFRAMPALQTAHYVRGQYQGYGDVPGVAKDSQTETYVAL
MAV_1252|M.avium_104 GADDLNDKKAEVFRAMPSLDPEHCVRGQYRGYTEVPGVAKDSTTETYVAL
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 RTEIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAFLPNRRPAEP
Rv1121|M.tuberculosis_H37Rv RTEIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAFLPNRRPAEP
MMAR_4339|M.marinum_M RTEIDNWRWAGVPVFLRAGKALPERVTEVRMFLHHVPGLAFLPNRRPAEP
MAV_1252|M.avium_104 RTEIDNWRWAGVPIFLRAGKALPHKVTEVRMFLHHVPGFSFLPNRRPPEP
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 NQIVLRIDPDPGMRLQISAHTDDSWRDIHLDSSFAVDLGEPIRPYERLLY
Rv1121|M.tuberculosis_H37Rv NQIVLRIDPDPGMRLQISAHTDDSWRDIHLDSSFAVDLGEPIRPYERLLY
MMAR_4339|M.marinum_M NQIVLRIDPDPGMRLQISAQTGDSWQGVHLDSSFAEDLGEPIRPYERLLY
MAV_1252|M.avium_104 NQIVLRIDPDPGMRLQLSAQVGDSWHDVHLDSSFAVDLGEPVRPYERLLY
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 AGLVGDHQLFAREDSIEQTWRIVQPLLDNPGEIHRYDRGSWGPEAAQSLL
Rv1121|M.tuberculosis_H37Rv AGLVGDHQLFAREDSIEQTWRIVQPLLDNPGEIHRYDRGSWGPEAAQSLL
MMAR_4339|M.marinum_M AGLIGDRQLFAREDAIEQTWRIVQPVLDDPGEIHPYDRGSWGPEAAQTLL
MAV_1252|M.avium_104 AAFNGDRQLFAREDAIEETWRIVQPVLDKPSRIHQYEQGSWGPEAAQALV
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 RGHRGWQSPWLPRGTDA--
Rv1121|M.tuberculosis_H37Rv RGHRGWQSPWLPRGTDA--
MMAR_4339|M.marinum_M RGHRNWQQPWLPRSAEARQ
MAV_1252|M.avium_104 HGRHAWQQPWLPQSTSTKR
Mflv_0499|M.gilvum_PYR-GCK -------------------
Mvan_5904|M.vanbaalenii_PYR-1 -------------------
MSMEG_5582|M.smegmatis_MC2_155 -------------------