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VAQLYDFFGEVFQRYFRPAVDAYPPLGGRPVEKIFTLTDAVQDPLEQSRRAALVWGHTEMGDAGFATELF VITQQGLVYAAELNNPRRSLYYLATPPSLFDPFVDQVERAELRQGAVVVVDNRFGRELATARPMDAALRR ILDEHWALRVDLSSPALC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5904 | - | - | 100% (159) | hypothetical protein Mvan_5904 |
| M. vanbaalenii PYR-1 | Mvan_2718 | - | 5e-05 | 28.95% (76) | glucose-6-phosphate 1-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1152 | zwf1 | 8e-10 | 45.31% (64) | glucose-6-phosphate 1-dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0499 | - | 7e-77 | 84.91% (159) | hypothetical protein Mflv_0499 |
| M. tuberculosis H37Rv | Rv1121 | zwf1 | 8e-10 | 45.31% (64) | glucose-6-phosphate 1-dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2761 | - | 4e-05 | 33.33% (66) | glucose-6-phosphate 1-dehydrogenase |
| M. marinum M | MMAR_4339 | zwf1 | 2e-12 | 43.06% (72) | glucose-6-phosphate 1-dehydrogenase Zwf1 |
| M. avium 104 | MAV_1252 | zwf | 5e-13 | 38.79% (116) | glucose-6-phosphate 1-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5582 | - | 2e-42 | 54.00% (150) | hypothetical protein MSMEG_5582 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1152|M.bovis_AF2122/97 MVDGGGGASDL---------------------LVIFGITGDLARKMTFRA
Rv1121|M.tuberculosis_H37Rv MVDGGGGASDL---------------------LVIFGITGDLARKMTFRA
MMAR_4339|M.marinum_M MANGGGQASDL---------------------LVIFGITGDLARKMTFRA
MAV_1252|M.avium_104 MADDDSHPSDL---------------------LVIFGITGDLARKMTFRA
MAB_2761|M.abscessus_ATCC_1997 MTEVLPPDSSLTANPLRDKRDKRLPRIAGPCSLVIFGVTGDLARKKLMPA
Mvan_5904|M.vanbaalenii_PYR-1 MVAQ------------------------------LYDFFGEVFQRYFRPA
Mflv_0499|M.gilvum_PYR-GCK MVAQ------------------------------LYDFFGEVFQRYFRPA
MSMEG_5582|M.smegmatis_MC2_155 MNDQ------------------------------VYDYFGSMFQRYFRPA
* ::. *.: :: *
Mb1152|M.bovis_AF2122/97 LYRLERHQLLD--CPILGVASDDMSVGQLVKWARESI-GRTEK-IDDAVF
Rv1121|M.tuberculosis_H37Rv LYRLERHQLLD--CPILGVASDDMSVGQLVKWARESI-GRTEK-IDDAVF
MMAR_4339|M.marinum_M LYRLERRGLLD--CPIVGVASDDMSVEQLVDRAREVIQGSSEP-FDEAVF
MAV_1252|M.avium_104 LYRLERREELE--HPIIGVASDDITLDQLLDRAREAIKATGET-FDDAVF
MAB_2761|M.abscessus_ATCC_1997 IYDLANRGLLPPSFALVGFARRDWANEDFGQIVLDAVKAHSRTPFRQHVW
Mvan_5904|M.vanbaalenii_PYR-1 VDAYPPLGGRP--------------VEKIFTLTDAVQDPLEQSRRAALVW
Mflv_0499|M.gilvum_PYR-GCK MDAYPPRGGGP--------------VERMFGLTDAVRDPLEQSRRAALAW
MSMEG_5582|M.smegmatis_MC2_155 VDEYPQTGGVL--------------VHRLMTSTDEVQDRVAEARHAAYAW
: : . . .:
Mb1152|M.bovis_AF2122/97 DRLAGRLSYLHGDVTDSQLYD-------SLAELIGSACRPLYYLEMPPAL
Rv1121|M.tuberculosis_H37Rv DRLAGRLSYLHGDVTDSQLYD-------SLAELIGSACRPLYYLEMPPAL
MMAR_4339|M.marinum_M ERFASRWSYLPGDVTDPALYT-------ALAKQIGHDRHGLYYLEMPPAL
MAV_1252|M.avium_104 DRLAGRLSYLSGDVTDTGLYS-------ELAEKIGGDSRPLYYLEMPPSL
MAB_2761|M.abscessus_ATCC_1997 DRLAEGIRFVQGSFDDDAAFEQLKKTLQTLDEERGTGGNHGFYLSIPPNA
Mvan_5904|M.vanbaalenii_PYR-1 GHTEMGDAGFATELFVITQQG------LVYAAELNNPRRSLYYLATPPSL
Mflv_0499|M.gilvum_PYR-GCK GHAEVDNARFATELFVITQHG------LIYAAELNNPRRSLYYLATPPSL
MSMEG_5582|M.smegmatis_MC2_155 SKVDLGTVDIASEFFMITQCG------LMYGARFAHPDHPHYYLATPAAL
: . .. . :** *.
Mb1152|M.bovis_AF2122/97 FAPIVENLANVRLLERA-----RVAVEKPFGHDLASALELNARLRAVLGE
Rv1121|M.tuberculosis_H37Rv FAPIVENLANVRLLERA-----RVAVEKPFGHDLASALELNARLRAVLGE
MMAR_4339|M.marinum_M FAPIVENLAKADLLRGA-----RVAVEKPFGHDLDSARELNSRLRAVLNE
MAV_1252|M.avium_104 FAPIVENLAKADLLERA-----RVAVEKPFGHDLESARDLNARLRAVLDE
MAB_2761|M.abscessus_ATCC_1997 FPTVCEQLSKSGLAQPVDGAWRRVVIEKPFGHDLASARELNAVVNEVFPE
Mvan_5904|M.vanbaalenii_PYR-1 FDPFVDQVERAELRQGA-----VVVVDNRFGRELATARPMDAALRRILDE
Mflv_0499|M.gilvum_PYR-GCK FDPFVDQVERARLREGG-----AVVVDNRLGRDLAAAHPMDAALRRILDQ
MSMEG_5582|M.smegmatis_MC2_155 FDAFVDQVECCDVHAGD-----VIGVDRRCSRDLSAAHPMDAALRRILDE
* .. ::: : : ::. .::* :* ::: :. :: :
Mb1152|M.bovis_AF2122/97 DQILRVDHFLGKQPVVELEYLRFANQALAELWDRNSISEIHITMAEDFGV
Rv1121|M.tuberculosis_H37Rv DQILRVDHFLGKQPVVELEYLRFANQALAELWDRNSISEIHITMAEDFGV
MMAR_4339|M.marinum_M DQILRVDHFLGKQPVVELQYLRFANRGLAELWDRKSVSEIHVTMAENFGV
MAV_1252|M.avium_104 DQILRVDHFLGKQPVEELQYLRFANNALAKLWDRDSISEIHITMAEDFGI
MAB_2761|M.abscessus_ATCC_1997 ESVFRIDHYLGKETVQNILALRFANQLFDPIWNAHFVDHVQITMAEDIGL
Mvan_5904|M.vanbaalenii_PYR-1 HWALRVDLSSPALC------------------------------------
Mflv_0499|M.gilvum_PYR-GCK HWALRVDLSSPALC------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 HETLRVNVG-----------------------------------------
. :*::
Mb1152|M.bovis_AF2122/97 EDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGSSADDLNDKKAEVFR
Rv1121|M.tuberculosis_H37Rv EDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGSSADDLNDKKAEVFR
MMAR_4339|M.marinum_M EDRGKFYDAVGALRDVVQNHLLQVLALVAMEPPVGPGADDLNDKKAEVFR
MAV_1252|M.avium_104 EDRGKFYDAVGAVRDVVQNHLLQVLALVAMEPPVGAGADDLNDKKAEVFR
MAB_2761|M.abscessus_ATCC_1997 GGRAGYYDGIGAARDVIQNHLLQLLAFTAMEEPINFSPAELQAEKIKVLS
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 AMAPLDP--DRCVRGQY----LGYTEVAGVASD------SATETYVALRT
Rv1121|M.tuberculosis_H37Rv AMAPLDP--DRCVRGQY----LGYTEVAGVASD------SATETYVALRT
MMAR_4339|M.marinum_M AMPALQT--AHYVRGQY----QGYGDVPGVAKD------SQTETYVALRT
MAV_1252|M.avium_104 AMPSLDP--EHCVRGQY----RGYTEVPGVAKD------STTETYVALRT
MAB_2761|M.abscessus_ATCC_1997 ATRLAEPLAETTARGQYGPGWQGSQQVPGLLEEEGFSKTSTTETFAAITL
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 EIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAFLPNRRPAE-PN
Rv1121|M.tuberculosis_H37Rv EIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAFLPNRRPAE-PN
MMAR_4339|M.marinum_M EIDNWRWAGVPVFLRAGKALPERVTEVRMFLHHVPGLAFLPNRRPAE-PN
MAV_1252|M.avium_104 EIDNWRWAGVPIFLRAGKALPHKVTEVRMFLHHVPGFSFLPNRRPPE-PN
MAB_2761|M.abscessus_ATCC_1997 EVDSRRWAGVPFYLRTGKRLGRRVTEIALVFKRAPHLPFDSTMTEELGAN
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 QIVLRIDPDPGMRLQISAHTDDS---WRDIHLDSSFAVDLG-EPIRPYER
Rv1121|M.tuberculosis_H37Rv QIVLRIDPDPGMRLQISAHTDDS---WRDIHLDSSFAVDLG-EPIRPYER
MMAR_4339|M.marinum_M QIVLRIDPDPGMRLQISAQTGDS---WQGVHLDSSFAEDLG-EPIRPYER
MAV_1252|M.avium_104 QIVLRIDPDPGMRLQLSAQVGDS---WHDVHLDSSFAVDLG-EPVRPYER
MAB_2761|M.abscessus_ATCC_1997 ALVIRVQPDEGVTLRFGSKVPGSAMEVRDVNMDFSYEQAFTEESPEAYER
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 LLYAGLVGDHQLFAREDSIEQTWRIVQPLLD---NPGEIHRYDRGSWGP-
Rv1121|M.tuberculosis_H37Rv LLYAGLVGDHQLFAREDSIEQTWRIVQPLLD---NPGEIHRYDRGSWGP-
MMAR_4339|M.marinum_M LLYAGLIGDRQLFAREDAIEQTWRIVQPVLD---DPGEIHPYDRGSWGP-
MAV_1252|M.avium_104 LLYAAFNGDRQLFAREDAIEETWRIVQPVLD---KPSRIHQYEQGSWGP-
MAB_2761|M.abscessus_ATCC_1997 LILDVLLGEPSLFPVNAEVELSWRILDPALDFWASQGRPDTYESGTWGPQ
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0499|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------------------------------
Mb1152|M.bovis_AF2122/97 EAAQSLLRGHRGWQSPWLPRGTDA--
Rv1121|M.tuberculosis_H37Rv EAAQSLLRGHRGWQSPWLPRGTDA--
MMAR_4339|M.marinum_M EAAQTLLRGHRNWQQPWLPRSAEARQ
MAV_1252|M.avium_104 EAAQALVHGRHAWQQPWLPQSTSTKR
MAB_2761|M.abscessus_ATCC_1997 SAVEMLARSGREWRRP----------
Mvan_5904|M.vanbaalenii_PYR-1 --------------------------
Mflv_0499|M.gilvum_PYR-GCK --------------------------
MSMEG_5582|M.smegmatis_MC2_155 --------------------------