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QNQVPRIRRPLPKLVLVRGDGDGWVVSASGAAFWGRHGAAGLLLRAPGPNGAPAVLLQHRAPWSHQGGTW GLPGGARDSHETPEQAAVREAEEEAGLSPHQLTVRTTVVTAENSGWTYTTVIADATEQLVTVPNRESAEL RWVAEDEVTNLPLHPGFAASWARLREVTALIPLMVNPQR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0199 | - | - | 100% (180) | NUDIX hydrolase |
| M. gilvum PYR-GCK | Mflv_3031 | - | 2e-08 | 29.59% (98) | NUDIX hydrolase |
| M. gilvum PYR-GCK | Mflv_2154 | - | 2e-06 | 33.65% (104) | NUDIX hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0421 | mutT3 | 1e-69 | 77.78% (162) | 7,8-dihydro-8-oxoguanine-triphosphatase |
| M. tuberculosis H37Rv | Rv0413 | mutT3 | 1e-69 | 77.78% (162) | 7,8-dihydro-8-oxoguanine-triphosphatase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4221c | - | 1e-58 | 68.79% (157) | MutT/NUDIX family mutator protein |
| M. marinum M | MMAR_0716 | mutT3 | 3e-63 | 70.91% (165) | mutator protein MutT3 |
| M. avium 104 | MAV_4747 | - | 4e-67 | 72.62% (168) | hydrolase, NUDIX family protein |
| M. smegmatis MC2 155 | MSMEG_0790 | - | 1e-68 | 80.62% (160) | hydrolase, NUDIX family protein |
| M. thermoresistible (build 8) | TH_2310 | mutT3 | 3e-68 | 74.40% (168) | POSSIBLE MUTATOR PROTEIN MUTT3 |
| M. ulcerans Agy99 | MUL_2807 | mutT3 | 2e-62 | 70.30% (165) | mutator protein MutT3 |
| M. vanbaalenii PYR-1 | Mvan_0706 | - | 8e-82 | 87.73% (163) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0199|M.gilvum_PYR-GCK MQNQVP-RIRRPLPKLVLVRGDGDGWVVSASGAAFWGRHGAAGLLLRAPG
Mvan_0706|M.vanbaalenii_PYR-1 MDSGAPNSVTVPYPER--VRGDGDGWVVSEAGNAYWGRHGAAGLLLRAPG
MSMEG_0790|M.smegmatis_MC2_155 --------------------------MMSENGARFWGRHGAAGLLLRAPM
TH_2310|M.thermoresistible__bu ------------------VRGDGDGWVMSESGARFWGRYGAAGLLLRAPR
Mb0421|M.bovis_AF2122/97 -------MPSCPPAYSEQVRGDGDGWVVSDSGVAYWGRYGAAGLLLRAPR
Rv0413|M.tuberculosis_H37Rv -------MPSCPPAYSEQVRGDGDGWVVSDSGVAYWGRYGAAGLLLRAPR
MMAR_0716|M.marinum_M ------------------MRGDGDGWVISESGVHYWGRFGSAGLLLRAPR
MUL_2807|M.ulcerans_Agy99 ------------------MRGDGDGWVISERGVHYWGRFGSAGLLLRAPR
MAV_4747|M.avium_104 ------------------MHGDGDGWVISERGAHYWGRYGAAGLLLRAPQ
MAB_4221c|M.abscessus_ATCC_199 ------------------MRGDGDGWVVADSGARFWGRFGAAGLLLRAPL
::: * :***.*:********
Mflv_0199|M.gilvum_PYR-GCK PNGAPAVLLQHRAPWSHQGGTWGLPGGARDSHETPEQAAVREAEEEAGLS
Mvan_0706|M.vanbaalenii_PYR-1 PGGSAAVLLQHRAPWSHQGGTWGLPGGARDSHETAEQAAVREAEEEAGLP
MSMEG_0790|M.smegmatis_MC2_155 PGGAAAVLLQHRAPWSHQGGTWALPGGARDSHETPEQAAVREAHEEAGLP
TH_2310|M.thermoresistible__bu PDGSPAVLLQHRAAWSHQGGTWGLPGGARDSHETAEQAAVREAHEETGLA
Mb0421|M.bovis_AF2122/97 PDGTPAVLLQHRALWSHQGGTWGLPGGARDSHETPEQTAVRESSEEAGLS
Rv0413|M.tuberculosis_H37Rv PDGTPAVLLQHRALWSHQGGTWGLPGGARDSHETPEQTAVRESSEEAGLS
MMAR_0716|M.marinum_M PDGTPAVLLQHRAFWSHQGGTWGLPGGARDSHETPEQTALREAHEEARLP
MUL_2807|M.ulcerans_Agy99 PDGAAAVLLQHRAFWSHQGGTWGLPGGARDSHETPEQTALREAHEEARLP
MAV_4747|M.avium_104 PDGTPAVLLQHRAVWSHQGGTWGLPGGARDSHETPEETAVREANEEAGLL
MAB_4221c|M.abscessus_ATCC_199 PNGQPAVLLQHRAWWSHQGGTWALPGGARDSHESAEEAALREAAEEAGVD
*.* .******** ********.**********:.*::*:**: **: :
Mflv_0199|M.gilvum_PYR-GCK PHQLTVRTTVVTAENSG-----WTYTTVIADATEQLVTVPNRESAELRWV
Mvan_0706|M.vanbaalenii_PYR-1 ADQLTVRTTVVTAEVSG-----WTYTTVIADAGEQLATIPNRESAELRWV
MSMEG_0790|M.smegmatis_MC2_155 AEQLTVRTTVVTAEVAGIGGTQWTYTTVIADAAEPLHTVPNRESAELRWV
TH_2310|M.thermoresistible__bu VELVVVRTAVVTAEVAGVGGTHWSYTTVIADAPEMLETEPNLESAELRWV
Mb0421|M.bovis_AF2122/97 AERLEVRATVVTAEVCGVDDTHWTYTTVVADAGELLDTVPNRESAELRWV
Rv0413|M.tuberculosis_H37Rv AERLEVRATVVTAEVCGVDDTHWTYTTVVADAGELLDTVPNRESAELRWV
MMAR_0716|M.marinum_M AERLTVRAVTVTARPSG---TAWTYTTVIADTRELLHAVPDRESAELRWV
MUL_2807|M.ulcerans_Agy99 AERLTVRAVTVTARPSG---TAWTYTTVIADTRELLHAVPDRESAELRWV
MAV_4747|M.avium_104 VDRLAVRASVVTAEVAGVGGTRWSYTTVIADADELLHTVPNRESAEMRWV
MAB_4221c|M.abscessus_ATCC_199 PAVMTVRSSVVTKRIDG--QAHWTYTTVIADAAELLPTAANHESTELRWV
: **: .** . * *:****:**: * * : .: **:*:***
Mflv_0199|M.gilvum_PYR-GCK AEDEVTNLPLHPGFAASWARLREVTALIPLMVNPQR--------------
Mvan_0706|M.vanbaalenii_PYR-1 AEDEVADLPLHPGFAASWERLREVTASIPLLVNPQR--------------
MSMEG_0790|M.smegmatis_MC2_155 LEDQVADLPLHPGFAASWQRLREVTATIPLLNR-QR--------------
TH_2310|M.thermoresistible__bu AEDDVGALPLHPGFAASWDGLRELIATIPLLTNDPR--------------
Mb0421|M.bovis_AF2122/97 AENEVADLPLHPGFAASWQRLRTAPATVPLARCDERRQRLPRTIQIEAGV
Rv0413|M.tuberculosis_H37Rv AENEVADLPLHPGFAASWQRLRTAPATVPLARCDERRQRLPRTIQIEAGV
MMAR_0716|M.marinum_M AEAEVVDFPLHPGFAASWQGLRCAPVTVPLERGDQRRELLPRTVEVEPGV
MUL_2807|M.ulcerans_Agy99 AEAEVVDFPLHPGFAASWQGLRCAPVTVPLERGDQRRELLPRTVEVEPGV
MAV_4747|M.avium_104 AEDEVADLPLHPGFAASWHRLRTEPARLPLSHGDERRQYLPRTIEPEDGV
MAB_4221c|M.abscessus_ATCC_199 PEEKIEGMRLHPGFKSSWPLLR-VVETLPHASNGFTGAG---TVELESGR
* .: : ***** :** ** :*
Mflv_0199|M.gilvum_PYR-GCK -------------------------------
Mvan_0706|M.vanbaalenii_PYR-1 -------------------------------
MSMEG_0790|M.smegmatis_MC2_155 -------------------------------
TH_2310|M.thermoresistible__bu -------------------------------
Mb0421|M.bovis_AF2122/97 FLWCTPG---DADQAPSPLGRRISSLL----
Rv0413|M.tuberculosis_H37Rv FLWCTPG---DADQAPSPLGRRISSLL----
MMAR_0716|M.marinum_M FVWCMPG---DADQVPSQLSPRVISLLEALT
MUL_2807|M.ulcerans_Agy99 FVWCMPG---DADQVPSQLSPRVISLLEALT
MAV_4747|M.avium_104 FVWCMPGDPADTDEASAQLCRRISALLPAPS
MAB_4221c|M.abscessus_ATCC_199 YAWQLP-------------------------