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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2310 | mutT3 | - | 100% (169) | POSSIBLE MUTATOR PROTEIN MUTT3 (7,8-DIHYDRO-8-OXOGUANINE-TRIPHOSPHATASE) (8-OXO-DGTPASE) (DGTP PYROPHOSPHOHYDROLASE) |
| M. thermoresistible (build 8) | TH_1236 | - | 4e-05 | 40.82% (49) | nudix hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0421 | mutT3 | 3e-72 | 74.40% (168) | 7,8-dihydro-8-oxoguanine-triphosphatase |
| M. gilvum PYR-GCK | Mflv_0199 | - | 4e-68 | 74.40% (168) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv0413 | mutT3 | 4e-72 | 74.40% (168) | 7,8-dihydro-8-oxoguanine-triphosphatase |
| M. leprae Br4923 | MLBr_01682 | - | 5e-05 | 38.89% (72) | hypothetical protein MLBr_01682 |
| M. abscessus ATCC 19977 | MAB_4221c | - | 7e-59 | 64.24% (165) | MutT/NUDIX family mutator protein |
| M. marinum M | MMAR_0716 | mutT3 | 2e-64 | 69.05% (168) | mutator protein MutT3 |
| M. avium 104 | MAV_4747 | - | 8e-73 | 75.60% (168) | hydrolase, NUDIX family protein |
| M. smegmatis MC2 155 | MSMEG_0790 | - | 2e-68 | 79.35% (155) | hydrolase, NUDIX family protein |
| M. ulcerans Agy99 | MUL_2807 | mutT3 | 5e-63 | 67.86% (168) | mutator protein MutT3 |
| M. vanbaalenii PYR-1 | Mvan_0706 | - | 3e-69 | 75.00% (168) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0199|M.gilvum_PYR-GCK --------------------MQNQVP-RIRRPLPKLVLVRGDGDGWVVSA
Mvan_0706|M.vanbaalenii_PYR-1 --------------------MDSGAPNSVTVPYPER--VRGDGDGWVVSE
MSMEG_0790|M.smegmatis_MC2_155 ----------------------------------------------MMSE
TH_2310|M.thermoresistible__bu --------------------------------------VRGDGDGWVMSE
Mb0421|M.bovis_AF2122/97 ---------------------------MPSCPPAYSEQVRGDGDGWVVSD
Rv0413|M.tuberculosis_H37Rv ---------------------------MPSCPPAYSEQVRGDGDGWVVSD
MMAR_0716|M.marinum_M --------------------------------------MRGDGDGWVISE
MUL_2807|M.ulcerans_Agy99 --------------------------------------MRGDGDGWVISE
MAV_4747|M.avium_104 --------------------------------------MHGDGDGWVISE
MAB_4221c|M.abscessus_ATCC_199 --------------------------------------MRGDGDGWVVAD
MLBr_01682|M.leprae_Br4923 MAIWNSSCQWPKSQIVYAAGAVLWRPGNSDPAVEIAVIHRPRYDDWSLSK
::
Mflv_0199|M.gilvum_PYR-GCK ------------------------------------------SGAAFWGR
Mvan_0706|M.vanbaalenii_PYR-1 ------------------------------------------AGNAYWGR
MSMEG_0790|M.smegmatis_MC2_155 ------------------------------------------NGARFWGR
TH_2310|M.thermoresistible__bu ------------------------------------------SGARFWGR
Mb0421|M.bovis_AF2122/97 ------------------------------------------SGVAYWGR
Rv0413|M.tuberculosis_H37Rv ------------------------------------------SGVAYWGR
MMAR_0716|M.marinum_M ------------------------------------------SGVHYWGR
MUL_2807|M.ulcerans_Agy99 ------------------------------------------RGVHYWGR
MAV_4747|M.avium_104 ------------------------------------------RGAHYWGR
MAB_4221c|M.abscessus_ATCC_199 ------------------------------------------SGARFWGR
MLBr_01682|M.leprae_Br4923 GKVDPGETAPMAAVREVFEETGHHATLGARLVVVNYPIGQHVKKVYYWAA
:*.
Mflv_0199|M.gilvum_PYR-GCK HGAAGLLLRAP----------GPNGAPAVLLQHRAPWSHQGGTWGLP---
Mvan_0706|M.vanbaalenii_PYR-1 HGAAGLLLRAP----------GPGGSAAVLLQHRAPWSHQGGTWGLP---
MSMEG_0790|M.smegmatis_MC2_155 HGAAGLLLRAP----------MPGGAAAVLLQHRAPWSHQGGTWALP---
TH_2310|M.thermoresistible__bu YGAAGLLLRAP----------RPDGSPAVLLQHRAAWSHQGGTWGLP---
Mb0421|M.bovis_AF2122/97 YGAAGLLLRAP----------RPDGTPAVLLQHRALWSHQGGTWGLP---
Rv0413|M.tuberculosis_H37Rv YGAAGLLLRAP----------RPDGTPAVLLQHRALWSHQGGTWGLP---
MMAR_0716|M.marinum_M FGSAGLLLRAP----------RPDGTPAVLLQHRAFWSHQGGTWGLP---
MUL_2807|M.ulcerans_Agy99 FGSAGLLLRAP----------RPDGAAAVLLQHRAFWSHQGGTWGLP---
MAV_4747|M.avium_104 YGAAGLLLRAP----------QPDGTPAVLLQHRAVWSHQGGTWGLP---
MAB_4221c|M.abscessus_ATCC_199 FGAAGLLLRAP----------LPNGQPAVLLQHRAWWSHQGGTWALP---
MLBr_01682|M.leprae_Br4923 RSIEGQFVPGSEVDELLWLPVVDAMKKLDYVQDRKVLRQFAKQPAYTRTV
. * :: .. :*.* : . . .
Mflv_0199|M.gilvum_PYR-GCK -----GGARDSHETPEQAAVREAEEEAGLSPHQLTVRTTVVTAENSG---
Mvan_0706|M.vanbaalenii_PYR-1 -----GGARDSHETAEQAAVREAEEEAGLPADQLTVRTTVVTAEVSG---
MSMEG_0790|M.smegmatis_MC2_155 -----GGARDSHETPEQAAVREAHEEAGLPAEQLTVRTTVVTAEVAGIGG
TH_2310|M.thermoresistible__bu -----GGARDSHETAEQAAVREAHEETGLAVELVVVRTAVVTAEVAGVGG
Mb0421|M.bovis_AF2122/97 -----GGARDSHETPEQTAVRESSEEAGLSAERLEVRATVVTAEVCGVDD
Rv0413|M.tuberculosis_H37Rv -----GGARDSHETPEQTAVRESSEEAGLSAERLEVRATVVTAEVCGVDD
MMAR_0716|M.marinum_M -----GGARDSHETPEQTALREAHEEARLPAERLTVRAVTVTARPSG---
MUL_2807|M.ulcerans_Agy99 -----GGARDSHETPEQTALREAHEEARLPAERLTVRAVTVTARPSG---
MAV_4747|M.avium_104 -----GGARDSHETPEETAVREANEEAGLLVDRLAVRASVVTAEVAGVGG
MAB_4221c|M.abscessus_ATCC_199 -----GGARDSHESAEEAALREAAEEAGVDPAVMTVRSSVVTKRIDG--Q
MLBr_01682|M.leprae_Br4923 LIVRHGTAGRKSRLSEDDTKRPLDKQGRAQAEALIGQLLAFGATDVYAAD
* * . . .*: : * :: : : ..
Mflv_0199|M.gilvum_PYR-GCK --WTYTTVIADATEQLVTVPNRESAELRWVAED------EVTNLPLHPGF
Mvan_0706|M.vanbaalenii_PYR-1 --WTYTTVIADAGEQLATIPNRESAELRWVAED------EVADLPLHPGF
MSMEG_0790|M.smegmatis_MC2_155 TQWTYTTVIADAAEPLHTVPNRESAELRWVLED------QVADLPLHPGF
TH_2310|M.thermoresistible__bu THWSYTTVIADAPEMLETEPNLESAELRWVAED------DVGALPLHPGF
Mb0421|M.bovis_AF2122/97 THWTYTTVVADAGELLDTVPNRESAELRWVAEN------EVADLPLHPGF
Rv0413|M.tuberculosis_H37Rv THWTYTTVVADAGELLDTVPNRESAELRWVAEN------EVADLPLHPGF
MMAR_0716|M.marinum_M TAWTYTTVIADTRELLHAVPDRESAELRWVAEA------EVVDFPLHPGF
MUL_2807|M.ulcerans_Agy99 TAWTYTTVIADTRELLHAVPDRESAELRWVAEA------EVVDFPLHPGF
MAV_4747|M.avium_104 TRWSYTTVIADADELLHTVPNRESAEMRWVAED------EVADLPLHPGF
MAB_4221c|M.abscessus_ATCC_199 AHWTYTTVIADAAELLPTAANHESTELRWVPEE------KIEGMRLHPGF
MLBr_01682|M.leprae_Br4923 QLHCHQTVEPLAAELGVPIHNEPSLTKEAFAKNPKRGLHRVLRIAAQSGT
: ** . : * . : * . . : : : :.*
Mflv_0199|M.gilvum_PYR-GCK AASWARLREVTALIPLMVNPQR----------------------------
Mvan_0706|M.vanbaalenii_PYR-1 AASWERLREVTASIPLLVNPQR----------------------------
MSMEG_0790|M.smegmatis_MC2_155 AASWQRLREVTATIPLLNR-QR----------------------------
TH_2310|M.thermoresistible__bu AASWDGLRELIATIPLLTNDPR----------------------------
Mb0421|M.bovis_AF2122/97 AASWQRLRTAPATVPLARCDERRQRLPRTIQIEAGVFLWCTPG---DADQ
Rv0413|M.tuberculosis_H37Rv AASWQRLRTAPATVPLARCDERRQRLPRTIQIEAGVFLWCTPG---DADQ
MMAR_0716|M.marinum_M AASWQGLRCAPVTVPLERGDQRRELLPRTVEVEPGVFVWCMPG---DADQ
MUL_2807|M.ulcerans_Agy99 AASWQGLRCAPVTVPLERGDQRRELLPRTVEVEPGVFVWCMPG---DADQ
MAV_4747|M.avium_104 AASWHRLRTEPARLPLSHGDERRQYLPRTIEPEDGVFVWCMPGDPADTDE
MAB_4221c|M.abscessus_ATCC_199 KSSWPLLR-VVETLPHASNGFTGAG---TVELESGRYAWQLP--------
MLBr_01682|M.leprae_Br4923 PVICLQGKIIPDLIAWWCERDGVRPKKSHNYKGSTWVLSLLAGQLVAVDH
: :.
Mflv_0199|M.gilvum_PYR-GCK -----------------
Mvan_0706|M.vanbaalenii_PYR-1 -----------------
MSMEG_0790|M.smegmatis_MC2_155 -----------------
TH_2310|M.thermoresistible__bu -----------------
Mb0421|M.bovis_AF2122/97 APSPLGRRISSLL----
Rv0413|M.tuberculosis_H37Rv APSPLGRRISSLL----
MMAR_0716|M.marinum_M VPSQLSPRVISLLEALT
MUL_2807|M.ulcerans_Agy99 VPSQLSPRVISLLEALT
MAV_4747|M.avium_104 ASAQLCRRISALLPAPS
MAB_4221c|M.abscessus_ATCC_199 -----------------
MLBr_01682|M.leprae_Br4923 VGSTLAANVQP------