For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RIDYYNDPNAPAPNSVVPSASAIVTDEHGRILLIKRRDNTLWALPGGGHDIGETIADTAVREVKEETGLD VEVTGLVGVYTNPHHVVAFTDGEVRQQFSLSFTTKVLGGTLAIDHESTDIAWTSPDDIPSLDMHPSMRLR IEHYLQHRDNPYLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3031 | - | - | 100% (155) | NUDIX hydrolase |
| M. gilvum PYR-GCK | Mflv_0844 | - | 9e-10 | 35.71% (98) | NUDIX hydrolase |
| M. gilvum PYR-GCK | Mflv_0199 | - | 2e-08 | 29.59% (98) | NUDIX hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3938 | - | 1e-08 | 34.69% (98) | hypothetical protein Mb3938 |
| M. tuberculosis H37Rv | Rv3908 | - | 1e-08 | 34.69% (98) | hypothetical protein Rv3908 |
| M. leprae Br4923 | MLBr_02698 | - | 4e-08 | 31.82% (110) | hypothetical protein MLBr_02698 |
| M. abscessus ATCC 19977 | MAB_2096c | - | 2e-82 | 92.90% (155) | putative MutT/NUDIX-like protein |
| M. marinum M | MMAR_3129 | - | 1e-84 | 94.84% (155) | hypothetical protein MMAR_3129 |
| M. avium 104 | MAV_3798 | - | 2e-79 | 90.26% (154) | nudix hydrolase |
| M. smegmatis MC2 155 | MSMEG_6927 | - | 4e-09 | 34.69% (98) | MutT/nudix family protein |
| M. thermoresistible (build 8) | TH_0645 | mutT2 | 2e-08 | 33.83% (133) | PROBABLE MUTATOR PROTEIN MUTT |
| M. ulcerans Agy99 | MUL_0524 | - | 3e-13 | 33.33% (132) | hypothetical protein MUL_0524 |
| M. vanbaalenii PYR-1 | Mvan_6062 | - | 3e-09 | 32.73% (110) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3031|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3129|M.marinum_M --------------------------------------------------
MAB_2096c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3798|M.avium_104 --------------------------------------------------
MSMEG_6927|M.smegmatis_MC2_155 -------MSDGEQAKPRRRRGRRRGHRRAQRAAGPPAAGAEHHTEPAADA
Mvan_6062|M.vanbaalenii_PYR-1 MPATIAWVSDGEQAKPRRRRGRRRGRR----AAGPPEA----LPDQAADH
Mb3938|M.bovis_AF2122/97 -------MSDGEQAKSRRRRGRRRGRR----AAATAEN--------HMDA
Rv3908|M.tuberculosis_H37Rv -------MSDGEQAKSRRRRGRRRGRR----AAATAEN--------HMDA
MLBr_02698|M.leprae_Br4923 MPAIIAWVSDGEQAKPRRRRKRRRGRD----ATRSAEN--------HTDR
MUL_0524|M.ulcerans_Agy99 --------------------------------------------------
TH_0645|M.thermoresistible__bu --------------------------------------------------
Mflv_3031|M.gilvum_PYR-GCK -----------------------------------------------MRI
MMAR_3129|M.marinum_M -----------------------------------------------MRT
MAB_2096c|M.abscessus_ATCC_199 -----------------------------------------------MRT
MAV_3798|M.avium_104 -----------------------------------------------MRT
MSMEG_6927|M.smegmatis_MC2_155 RTESRADTRSDTSSAPTPATQPGEKKPGPGRGSRAGAAKPTPKDQPKQRK
Mvan_6062|M.vanbaalenii_PYR-1 R-----------QQAPPAGT--------------AGQARQTPKPQ----R
Mb3938|M.bovis_AF2122/97 QP--------------------------------AGDATPTPATAKRSRS
Rv3908|M.tuberculosis_H37Rv QP--------------------------------AGDATPTPATAKRSRS
MLBr_02698|M.leprae_Br4923 QV--------------------------------ANDATAT----KPRRS
MUL_0524|M.ulcerans_Agy99 --------------------------------------------------
TH_0645|M.thermoresistible__bu --------------------------------------------------
Mflv_3031|M.gilvum_PYR-GCK DYYNDPNAPAPNSVVPSASAIVTD---------EHGRILLIKRRD--NTL
MMAR_3129|M.marinum_M DYYNDPNAPLPNSVVPSASAIVTD---------EQGRILLIKRRD--NTL
MAB_2096c|M.abscessus_ATCC_199 DYYNDPNAPAPNSVVPSASAIVTD---------EQGRILLIKRRD--NTL
MAV_3798|M.avium_104 DYYNDPNAPRPNSVVPSASAIVAD---------ERGRILLIKRRD--NTL
MSMEG_6927|M.smegmatis_MC2_155 NRPRRPPDRLRTVHETSAGGLVIDGIDGPKDSQVAALIGRLDRRG--RML
Mvan_6062|M.vanbaalenii_PYR-1 TRTRRPPERLRTVHETSAGGLVIDGIDGPKDGQVAALIGRIDRRG--RML
Mb3938|M.bovis_AF2122/97 RSPRRGSTRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRVDRRG--RLL
Rv3908|M.tuberculosis_H37Rv RSPRRGSTRMRTVHETSAGGLVIDGIDGPRDAQVAALIGRVDRRG--RLL
MLBr_02698|M.leprae_Br4923 HSPHRAPEQLRTVHETSAGGLVIYGIDGPRDAQVAALIGRIDRRG--RML
MUL_0524|M.ulcerans_Agy99 -----MRMAATPKHSVSVAGIVVR---------DDGRVLVIKRDD--NGH
TH_0645|M.thermoresistible__bu ------MTQIPQPQIVVAGALIAD---------AALLVAQRNRPPELAGR
...:: : .*
Mflv_3031|M.gilvum_PYR-GCK WALPGGGHDIGETIADTAVREVKEETGLDVEVTGLVG------------V
MMAR_3129|M.marinum_M WALPGGGHDIGETIADTAVREVKEETGLDIEVTGLVG------------V
MAB_2096c|M.abscessus_ATCC_199 WALPGGGHDIGETIADTAVREVKEETGLDVEVTGLVG------------V
MAV_3798|M.avium_104 WALPGGGHDIGETIEQTAVREVKEETGLDVEITGLVG------------V
MSMEG_6927|M.smegmatis_MC2_155 WSLPKGHIELGETAEQTAIREVAEETGIQGSVLAALGSIDYWFVTEGRRV
Mvan_6062|M.vanbaalenii_PYR-1 WSLPKGHIEMGETAEQTAIREVAEETGIQGSVLAALGSIDYWFVTEGRRV
Mb3938|M.bovis_AF2122/97 WSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVTDGRRV
Rv3908|M.tuberculosis_H37Rv WSLPKGHIELGETAEQTAIREVAEETGIRGSVLAALGRIDYWFVTDGRRV
MLBr_02698|M.leprae_Br4923 WSLPKGHIEQGETAEQTAIREVAEETGIRGSVLAALGQIDYWFVTDDCRV
MUL_0524|M.ulcerans_Agy99 WEAPGGVLELDESFEAGVQREVLEETGVEVTVERLTG------------V
TH_0645|M.thermoresistible__bu WELPGGKVAPGETEAEALVRELKEELGVDVEVGARLG-------------
* * * .*: **: ** *: : *
Mflv_3031|M.gilvum_PYR-GCK YTNPHHVVA------FTDGEVRQQFSLSFTTKVLGGTLAIDHES------
MMAR_3129|M.marinum_M YTNPQHVVA------FTDGEVRQQFSLSFTTKVLGGTLAIDHES------
MAB_2096c|M.abscessus_ATCC_199 YTNPHHVVA------FTDGEVRQQFSLLFATTVLGGTLAIDHES------
MAV_3798|M.avium_104 YTNPRHVVA------FTDGEVRQQFSLLFTTRVLGGELAIDHES------
MSMEG_6927|M.smegmatis_MC2_155 HKTVHHYLMRFLGGELSDDDVEVTEVAWVPLRELPSRLAYADERRLAEVA
Mvan_6062|M.vanbaalenii_PYR-1 HKTVHHYLMRFSGGELSDEDVEVTEVAWVPVKDLPSRLAYADERRLAEVA
Mb3938|M.bovis_AF2122/97 HKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADERRLAEVA
Rv3908|M.tuberculosis_H37Rv HKTVHHYLMRFLGGELSDEDLEVAEVAWVPIRELPSRLAYADERRLAEVA
MLBr_02698|M.leprae_Br4923 HKTVHHYLMRFSGGELSDDDLEVTEVAWVPIRELPSRLAYADERRLAEVA
MUL_0524|M.ulcerans_Agy99 YKNLAHGIVA-----LVYRCRPLGDEAHATEEACEIRWMTKEEVQS----
TH_0645|M.thermoresistible__bu ---------------VEVALTESMVLRAFRVHHRGGSPSPNDHR------
. ..
Mflv_3031|M.gilvum_PYR-GCK ----TDIAWTSPDDIPSLDMHPSMRLRIEHYLQHRDN-------------
MMAR_3129|M.marinum_M ----TDIAWTDPDDIPNLDMHPSMRLRIEHYLQHRDS-------------
MAB_2096c|M.abscessus_ATCC_199 ----TDIAWTAPDDIAGLDMHPSMRLRVEHYLQRRDS-------------
MAV_3798|M.avium_104 ----TDIAWTDPDDIADLDMHPSMRLRIEHYLQHRDS-------------
MSMEG_6927|M.smegmatis_MC2_155 GELIDKLHTGGPAALPPLPHSAPRRRAQTHSHTRNRR-DDTAQPQARRRT
Mvan_6062|M.vanbaalenii_PYR-1 DELIDKLHTDGPGALPPLPRTTPRRRGQTHSHTRRHRPDPTAQPQPGRRT
Mb3938|M.bovis_AF2122/97 DELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHAD--DSAPGQ----H
Rv3908|M.tuberculosis_H37Rv DELIDKLQSDGPAALPPLPPSSPRRRPQTHSRARHAD--DSAPGQ----H
MLBr_02698|M.leprae_Br4923 YELINKLQTGGPAALPPLPPSLPRRQSQTHFRTRHSN--NSANSR----K
MUL_0524|M.ulcerans_Agy99 ----AMVPAFGVRVLDAFEEAPQSRAHDGVNLVRV---------------
TH_0645|M.thermoresistible__bu -----ALRWVTAAELHDLDWVPADRAWIPELTALLSAR------------
: : : *
Mflv_3031|M.gilvum_PYR-GCK --PYLG-
MMAR_3129|M.marinum_M --PYLG-
MAB_2096c|M.abscessus_ATCC_199 --PYLG-
MAV_3798|M.avium_104 --PYLC-
MSMEG_6927|M.smegmatis_MC2_155 NGCGQGP
Mvan_6062|M.vanbaalenii_PYR-1 NGCGQGP
Mb3938|M.bovis_AF2122/97 NGPGPGP
Rv3908|M.tuberculosis_H37Rv NGPGPGP
MLBr_02698|M.leprae_Br4923 NGHGQGP
MUL_0524|M.ulcerans_Agy99 -------
TH_0645|M.thermoresistible__bu -------