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AFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAGADDVSQAIAALLSSHGAQYQALSAQAAQ FHQGFMQLLNSAGGAYAGAEAANVSPLQTLESNVLGALNTPTQAIFGRPLIGDGANGTATSPNGGAGGFL YGNGGNGYSFTSGGTQSGGTGGSAGLIGNGGNGGNGFLGGAGGAAGSGGWLAGSGGNGGAGGSVTGVGEV GGAGGAGGSAPLLGWGGNGGAGGDSTQGAGGMGGAGGAGGALASIGGAGGAGGTGTTSGGDGGVGGEGSG RLFGLGGAGGAGGTGITSGGVGGDGGAGGGLLFGLGGSGGAGGVATDATGIGGTGGAGGESGVIIGYAQS GAGGIGGYGGDIGGTGGAGGVAGVLVGAGVGGFGGMGGAGTTGGAGGVGGQGVTLTGLGVGGIGGVGGFG TATGGDGGAGGQGAALWGAGFGGDGAVGGNSFVGAGGNGGDGGNGGGLFNIGRGGDGGNGGNAGATGGNG GNGGNIGVVANGTFTQTLFGDGGNGGNGGTGGTPGTGGTGGSGGILIGADGTNGS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2113 | - | - | 100% (546) | PE-PGRS family protein |
M. marinum M | MMAR_2112 | - | 0.0 | 65.69% (580) | PE-PGRS family protein |
M. marinum M | MMAR_3199 | - | e-157 | 51.87% (615) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2622 | PE_PGRS44 | 0.0 | 64.00% (550) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 4e-94 | 46.09% (512) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv2591 | PE_PGRS44 | 0.0 | 63.82% (550) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 1e-14 | 42.39% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 1e-45 | 35.14% (424) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 2e-23 | 39.04% (187) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 7e-82 | 39.52% (587) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 3e-38 | 40.85% (284) | PUTATIVE - |
M. ulcerans Agy99 | MUL_1718 | - | 0.0 | 76.10% (502) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 8e-89 | 42.24% (554) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS MMAR_2113|M.marinum_M -------MAFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAG MUL_1718|M.ulcerans_Agy99 -------MAFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAG Mb2622|M.bovis_AF2122/97 -------MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAG Rv2591|M.tuberculosis_H37Rv -------MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAG Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------------------------------VD MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT MMAR_2113|M.marinum_M ADDVSQAIAALLSSHGAQYQALSAQAAQFHQGFMQLLNSAGGAYAGAEAA MUL_1718|M.ulcerans_Agy99 ADDVSQAFAALLSSHGAQYQALSAQAAQFHQGLMQLLNSAGGAYAGAEAA Mb2622|M.bovis_AF2122/97 ADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAA Rv2591|M.tuberculosis_H37Rv ADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAA Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA MMAR_2113|M.marinum_M NVSPLQTLESNVLGALNTPTQAIFGRPLIGDGANG--------------- MUL_1718|M.ulcerans_Agy99 NVSPLQTLESNVVGALNTPTQAIFGRPLIGDGANG--------------- Mb2622|M.bovis_AF2122/97 NAS-AQALEQNLLAVINAPAQALFGRPLIGNGANG--------------- Rv2591|M.tuberculosis_H37Rv NAS-AQALEQNLLAVINAPAQALFGRPLIGNGANG--------------- Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG--------------- MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS--------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------ Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------ MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2113|M.marinum_M --------------TATSPNGGAGGFLY---------------------- MUL_1718|M.ulcerans_Agy99 --------------TATSPNGGAGGFLY---------------------- Mb2622|M.bovis_AF2122/97 --------------TAASPNGGDGGILY---------------------- Rv2591|M.tuberculosis_H37Rv --------------TAASPNGGDGGILY---------------------- Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF MAB_4284c|M.abscessus_ATCC_199 --------PIASGQGSTAVNGDVRDSN-----IINADHGSNVGVDQSQTR MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------IPDVYKQQIRAESYGDAAGQLS---------------AMVAGLE MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ETGTTG---GAGGVG--------------------GQGTAGGTGGVGGIG Mvan_1264|M.vanbaalenii_PYR-1 ETGVTG---GVGGIG--------------------GQGTEGGTGGVGGVG MSMEG_0868|M.smegmatis_MC2_155 TGTGIG---GNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG TH_3810|M.thermoresistible__bu SLFNLG---GAGGWG--------------------GSGVDG--------- MAB_4284c|M.abscessus_ATCC_199 VGGDYTNVSGHG-----------------------SADIDKSVTVVDDHS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 KLESLP-------------------------------------------- MMAR_2113|M.marinum_M -------------------------------------------------- MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 -------------------------------------------------- Rv2591|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GAG----------STGAVGG-------VGGKG----IQGGQG-------- Mvan_1264|M.vanbaalenii_PYR-1 GVG----------ATGGAGG-------VGGKG----IQGGQG-------- MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS TH_3810|M.thermoresistible__bu --------------VDVVGG------------------------------ MAB_4284c|M.abscessus_ATCC_199 QRN----------TTNINDS------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MMAR_2113|M.marinum_M --------------GNGGNG--------------------------YSFT MUL_1718|M.ulcerans_Agy99 --------------GNGGNG--------------------------YSFT Mb2622|M.bovis_AF2122/97 --------------GNGGNG--------------------------FSQT Rv2591|M.tuberculosis_H37Rv --------------GNGGNG--------------------------FSQT Mflv_5091|M.gilvum_PYR-GCK -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT Mvan_1264|M.vanbaalenii_PYR-1 -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN TH_3810|M.thermoresistible__bu ----------NPDGGTPG------------------------------AH MAB_4284c|M.abscessus_ATCC_199 -----FNTDRSTNIGSGNTTNTEIGSHN------------------QANI MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------GGLLLVGSGVDVAPLKQVLQTTTFLDVS----------VAEE MMAR_2113|M.marinum_M SGGTQSGGTGGSAGLIG--------------------------------- MUL_1718|M.ulcerans_Agy99 SGGTQSGGTGGSAGLIG--------------------------------- Mb2622|M.bovis_AF2122/97 TAG-VAGGAGGSAGLIG--------------------------------- Rv2591|M.tuberculosis_H37Rv TAG-VAGGAGGSAGLIG--------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------- Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------- MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP TH_3810|M.thermoresistible__bu GESHTPGVYTDRQ------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GTSTSAGGSAAVGGNAG--------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PETALARGAALAAANAP--------------------------------- MMAR_2113|M.marinum_M -----------------NGGNGGNGFLGGAGGAAGSGG------------ MUL_1718|M.ulcerans_Agy99 -----------------NGGNGGNGFLGGAGGAAGSGG------------ Mb2622|M.bovis_AF2122/97 -----------------NGGNGGAGGAGAAGGAGGAGG------------ Rv2591|M.tuberculosis_H37Rv -----------------NGGNGGAGGAGAAGGAGGAGG------------ Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGAGGAGGTGG-TGGAGGTGG------------ Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGNGGNGGTGG-TGGNGGTGG------------ MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS TH_3810|M.thermoresistible__bu ------------------GEDGEDGTGTGIGGRGGNGG------------ MAB_4284c|M.abscessus_ATCC_199 ----------------LAGNAGLAGNAGLAGNAGLAGN------------ MLBr_01183|M.leprae_Br4923 -------------------------MPLFLNAEPQALT------------ MAV_4827|M.avium_104 ----------------LFASSTAALAYAQDPGTGAVDQYS---------- MMAR_2113|M.marinum_M ----WLAGSGGNGGAGGS--VTGVGEVGGAGGAGGSAPLLGWGGNGGAGG MUL_1718|M.ulcerans_Agy99 ----WLAGSGGNGGAGGS--VTGVGEVGGAGGAGGSAPLLGWGGNGGAGG Mb2622|M.bovis_AF2122/97 ----WLLGNGGAGGPGGP--TDVPAGTGGAGGAGGDAPLIGWGGNGGPGG Rv2591|M.tuberculosis_H37Rv ----WLLGNGGAGGPGGP--TDVPAGTGGAGGAGGDAPLIGWGGNGGPGG Mflv_5091|M.gilvum_PYR-GCK -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGHGG TH_3810|M.thermoresistible__bu ----SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGSHGG MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG MLBr_01183|M.leprae_Br4923 ------AAANTLEGLS-------AATVASNAAAAQLT-----TEIAPPAA MAV_4827|M.avium_104 --LPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRR . . . MMAR_2113|M.marinum_M DSTQG-AGGMGGAGGAGG---ALASIGGAGGAGGTGT--------TSGGD MUL_1718|M.ulcerans_Agy99 DSTQG-TGGRGGAGGAGG---ALAAIGGAGGAGGTGA--------TAGGD Mb2622|M.bovis_AF2122/97 FAAFG-NGGAGGNGGASG---SLFGVGGAGGVGGSSE--------DVGGT Rv2591|M.tuberculosis_H37Rv FAAFG-NGGAGGNGGASG---SLFGVGGAGGVGGSSE--------DVGGT Mflv_5091|M.gilvum_PYR-GCK TGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGT Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGT MSMEG_0868|M.smegmatis_MC2_155 DGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGN TH_3810|M.thermoresistible__bu NGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDAD MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNA MLBr_01183|M.leprae_Br4923 DDVSILLAHFFSGHGR--------QYQAHASQGATN---------HQDLI MAV_4827|M.avium_104 RPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTE . . . MMAR_2113|M.marinum_M GGVGGEG-------------SGRLFGLGG--------------------- MUL_1718|M.ulcerans_Agy99 GGVGGEG-------------SGRLFGLGG--------------------- Mb2622|M.bovis_AF2122/97 GGAGGAG-------------RGLFLGLGG--------------------- Rv2591|M.tuberculosis_H37Rv GGAGGAG-------------RGLFLGLGG--------------------- Mflv_5091|M.gilvum_PYR-GCK GGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----- Mvan_1264|M.vanbaalenii_PYR-1 GGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----- MSMEG_0868|M.smegmatis_MC2_155 GGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIR TH_3810|M.thermoresistible__bu GGNGGDG---------------GNGGSAG--------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAG-------------LAGNAGLAG--------------------- MLBr_01183|M.leprae_Br4923 QSLLTSS-----------------SAYAG--------------------- MAV_4827|M.avium_104 QAPAPPP-------------VQASAPQPK--------------------- MMAR_2113|M.marinum_M ------------AGGAGGTGITSGGVGGDG-------------------- MUL_1718|M.ulcerans_Agy99 ------------AGGAGGTGTTSGGVGG---------------------- Mb2622|M.bovis_AF2122/97 ------------DGGAGGTSNNNGGDGGAG-------------------- Rv2591|M.tuberculosis_H37Rv ------------DGGAGGTSNNNGGDGGAG-------------------- Mflv_5091|M.gilvum_PYR-GCK ------------TGGTGGQGG-LGGGGGTG-------------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------TGGTGGQGG-LGGVGGTG-------------------- MSMEG_0868|M.smegmatis_MC2_155 ATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGT TH_3810|M.thermoresistible__bu ------------RGGTGGLRGVFGINGGNG-------------------- MAB_4284c|M.abscessus_ATCC_199 ------------NAAVAGNAAVAGNAAVAG-------------------- MLBr_01183|M.leprae_Br4923 -------------TETANHDSL---------------------------- MAV_4827|M.avium_104 ------ISVPEPVAAPKPLSPPVAAPLPAAP------------------- MMAR_2113|M.marinum_M ----GAGGGLLFGLGGSGGAGGVATDA----------TGIGGTGGAGGES MUL_1718|M.ulcerans_Agy99 -------------------------------------------------- Mb2622|M.bovis_AF2122/97 ----GTAGGRLFSLGGDGGNGGAGTAI----------GSNAGDGGAGGDS Rv2591|M.tuberculosis_H37Rv ----GTAGGRLFSLGGDGGNGGAGTAI----------GSNAGDGGAGGDS Mflv_5091|M.gilvum_PYR-GCK ---GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLG Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLG MSMEG_0868|M.smegmatis_MC2_155 ATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLG TH_3810|M.thermoresistible__bu ----RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGG MAB_4284c|M.abscessus_ATCC_199 ----NAAVGGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQ MMAR_2113|M.marinum_M GVIIGYAQSGAGGIGGYGGDIGGTGGAGG--------------------- MUL_1718|M.ulcerans_Agy99 -----------------------TGGAGG--------------------- Mb2622|M.bovis_AF2122/97 SALIGYAQGGSGGLGGFGESTGGDGGLGG--------------------- Rv2591|M.tuberculosis_H37Rv SALIGYAQGGSGGLGGFGESTGGDGGLGG--------------------- Mflv_5091|M.gilvum_PYR-GCK GFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSG Mvan_1264|M.vanbaalenii_PYR-1 GFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSG MSMEG_0868|M.smegmatis_MC2_155 GNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSG TH_3810|M.thermoresistible__bu GTPSAGFGVPTTIQFPAGSCTSRAVSREG--------------------- MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTGVGGGVSTGVGVGSHVGG--------------------G MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 LLAPPRLSVPQPVQPPVRVPQPPSPPQVG--------------------- MMAR_2113|M.marinum_M VAGVLVGAGVGGFGGMGG-AGTTGGAGGVG-------------GQGVTLT MUL_1718|M.ulcerans_Agy99 VAGVLVGAGVGGFGGMGG-AGTTGGAGDVG-------------GQGVTLT Mb2622|M.bovis_AF2122/97 AGAVLIGTGVGGFGGLGGGSNGTGGAGGAG-------------GTGATLI Rv2591|M.tuberculosis_H37Rv AGAVLIGTGVGGFGGLGGGSNGTGGAGGAG-------------GTGATLI Mflv_5091|M.gilvum_PYR-GCK SAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGK Mvan_1264|M.vanbaalenii_PYR-1 SAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGA MSMEG_0868|M.smegmatis_MC2_155 YGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTAT TH_3810|M.thermoresistible__bu ---IMPSSRAASARAG---------------------------AACASST MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -GTVPQSPPQHQTPPGEGTPPKPDGPGNYG---------------GGHVP MMAR_2113|M.marinum_M GLGVGGIGGVG-------------------GFGTATG----GDGGAGGQG MUL_1718|M.ulcerans_Agy99 GLGVGGIGGVG-------------------GFGTATG----GDGGAGGQG Mb2622|M.bovis_AF2122/97 GLGAGGGGSIG-------------------GFAVNVGNGVGGLGGQGGQG Rv2591|M.tuberculosis_H37Rv GLGAGGGGGIG-------------------GFAVNVGNGVGGLGGQGGQG Mflv_5091|M.gilvum_PYR-GCK AGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQG Mvan_1264|M.vanbaalenii_PYR-1 QGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQG MSMEG_0868|M.smegmatis_MC2_155 GGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKG TH_3810|M.thermoresistible__bu SRSRRSFCCSRA-------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 TPGAGGSGGSG-------------------GGHVPTPGAGGSGGSGGGHV MMAR_2113|M.marinum_M AALWGAGFGGDGAVG---GNSFVGAGGNGGDGGNGGGLFNIGRGGDGG-- MUL_1718|M.ulcerans_Agy99 AALWGAGFGGDGAVG---GNSFVGAGGNGGDGGNGGGLFNIGRGGDGG-- Mb2622|M.bovis_AF2122/97 AALIGLGAGGAGGAG---GATVVGLGGNDGDGGDGGGLFSIGVGGDGG-- Rv2591|M.tuberculosis_H37Rv AALIGLGAGGAGGAG---GATVVGLGGNGGDGGDGGGLFSIGVGGDGG-- Mflv_5091|M.gilvum_PYR-GCK AAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-- Mvan_1264|M.vanbaalenii_PYR-1 AAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-- MSMEG_0868|M.smegmatis_MC2_155 ADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PTPGTGGPGGTGGSG---GGHVPTPGAGTPGGSGGGHLPFPGAGSTPG-- MMAR_2113|M.marinum_M ---------NGGNAGATGGNGGNGGNIGVVANGTFTQTLFGDGGNGGNGG MUL_1718|M.ulcerans_Agy99 ---------NGGNAGATGGNG---GNIGVVANGTFTQTLFGDGGNGGNGG Mb2622|M.bovis_AF2122/97 ---------NAGN-GAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGV Rv2591|M.tuberculosis_H37Rv ---------NAGN-GAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGV Mflv_5091|M.gilvum_PYR-GCK ---------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGA Mvan_1264|M.vanbaalenii_PYR-1 ---------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGT MSMEG_0868|M.smegmatis_MC2_155 SVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------GSGGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGGH MMAR_2113|M.marinum_M TGGTPGTGGTGGSGGILIGADGTNGS------ MUL_1718|M.ulcerans_Agy99 NGGTGGTPGTGGSGGILIGADGTNGS------ Mb2622|M.bovis_AF2122/97 NGGTG---GTGGSGGILFGANGANGPS----- Rv2591|M.tuberculosis_H37Rv NG------GTGGSGGILFGANGANGPS----- Mflv_5091|M.gilvum_PYR-GCK GGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 GGAG--GAGGSGGSGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 GGSGNGGNGGNGGNGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu -------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGTGFEAQGHAQGHASETAHTTLPGAEHH--- MLBr_01183|M.leprae_Br4923 -------------------------------- MAV_4827|M.avium_104 APAPGGGLGGFGGGHSGGGLGGLGGGHK----