For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAGADDVSQAFAALLSSHGAQYQALSAQAAQ FHQGLMQLLNSAGGAYAGAEAANVSPLQTLESNVVGALNTPTQAIFGRPLIGDGANGTATSPNGGAGGFL YGNGGNGYSFTSGGTQSGGTGGSAGLIGNGGNGGNGFLGGAGGAAGSGGWLAGSGGNGGAGGSVTGVGEV GGAGGAGGSAPLLGWGGNGGAGGDSTQGTGGRGGAGGAGGALAAIGGAGGAGGTGATAGGDGGVGGEGSG RLFGLGGAGGAGGTGTTSGGVGGTGGAGGVAGVLVGAGVGGFGGMGGAGTTGGAGDVGGQGVTLTGLGVG GIGGVGGFGTATGGDGGAGGQGAALWGAGFGGDGAVGGNSFVGAGGNGGDGGNGGGLFNIGRGGDGGNGG NAGATGGNGGNIGVVANGTFTQTLFGDGGNGGNGGNGGTGGTPGTGGSGGILIGADGTNGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1718 | - | - | 100% (482) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3507 | - | e-133 | 51.73% (520) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_0572 | - | e-121 | 51.26% (515) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2622 | PE_PGRS44 | 1e-170 | 57.38% (549) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-77 | 47.86% (374) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv2591 | PE_PGRS44 | 1e-169 | 57.19% (549) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 7e-15 | 43.48% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-42 | 36.07% (366) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2113 | - | 0.0 | 85.16% (546) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 2e-22 | 43.27% (171) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 8e-74 | 43.04% (460) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-36 | 40.78% (282) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 3e-78 | 49.60% (371) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
MUL_1718|M.ulcerans_Agy99 -------MAFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAG
MMAR_2113|M.marinum_M -------MAFVIAAPELVSAAAENVASIGTSLGAANAAVAASTTSVLSAG
Mb2622|M.bovis_AF2122/97 -------MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAG
Rv2591|M.tuberculosis_H37Rv -------MSFVTAAPEMLATAAQNVANIGTSLSAANATAAASTTSVLAAG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
MUL_1718|M.ulcerans_Agy99 ADDVSQAFAALLSSHGAQYQALSAQAAQFHQGLMQLLNSAGGAYAGAEAA
MMAR_2113|M.marinum_M ADDVSQAIAALLSSHGAQYQALSAQAAQFHQGFMQLLNSAGGAYAGAEAA
Mb2622|M.bovis_AF2122/97 ADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAA
Rv2591|M.tuberculosis_H37Rv ADEVSQAIARLFSDYATHYQSLNAQAAAFHHSFVQTLNAAGGAYSSAEAA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
MUL_1718|M.ulcerans_Agy99 NVSPLQTLESNVVGALNTPTQAIFGRPLIGDGANG---------------
MMAR_2113|M.marinum_M NVSPLQTLESNVLGALNTPTQAIFGRPLIGDGANG---------------
Mb2622|M.bovis_AF2122/97 NAS-AQALEQNLLAVINAPAQALFGRPLIGNGANG---------------
Rv2591|M.tuberculosis_H37Rv NAS-AQALEQNLLAVINAPAQALFGRPLIGNGANG---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS---------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------TATSPNGGAGGFLY----------------------
MMAR_2113|M.marinum_M --------------TATSPNGGAGGFLY----------------------
Mb2622|M.bovis_AF2122/97 --------------TAASPNGGDGGILY----------------------
Rv2591|M.tuberculosis_H37Rv --------------TAASPNGGDGGILY----------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF
MAB_4284c|M.abscessus_ATCC_199 --------PIASGQGSTAVNGDVRDSN-----IINADHGSNVGVDQSQTR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------IPDVYKQQIRAESYGDAAGQLS---------------AMVAGLE
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ETGTTG---GAGGVG--------------------GQGTAGGTGGVGGIG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTG---GVGGIG--------------------GQGTEGGTGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIG---GNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG
TH_3810|M.thermoresistible__bu SLFNLG---GAGGWG--------------------GSGVDG---------
MAB_4284c|M.abscessus_ATCC_199 VGGDYTNVSGHG-----------------------SADIDKSVTVVDDHS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 KLESLP--------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M --------------------------------------------------
Mb2622|M.bovis_AF2122/97 --------------------------------------------------
Rv2591|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAG----------STGAVGG-------VGGKG----IQGGQG--------
Mvan_1264|M.vanbaalenii_PYR-1 GVG----------ATGGAGG-------VGGKG----IQGGQG--------
MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS
TH_3810|M.thermoresistible__bu --------------VDVVGG------------------------------
MAB_4284c|M.abscessus_ATCC_199 QRN----------TTNINDS------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_1718|M.ulcerans_Agy99 --------------GNGGNG--------------------------YSFT
MMAR_2113|M.marinum_M --------------GNGGNG--------------------------YSFT
Mb2622|M.bovis_AF2122/97 --------------GNGGNG--------------------------FSQT
Rv2591|M.tuberculosis_H37Rv --------------GNGGNG--------------------------FSQT
Mflv_5091|M.gilvum_PYR-GCK -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT
Mvan_1264|M.vanbaalenii_PYR-1 -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT
MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN
TH_3810|M.thermoresistible__bu ----------NPDGGTPG------------------------------AH
MAB_4284c|M.abscessus_ATCC_199 -----FNTDRSTNIGSGNTTNTEIGSHN------------------QANI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------GGLLLVGSGVDVAPLKQVLQTTTFLDVS----------VAEE
MUL_1718|M.ulcerans_Agy99 SGGTQSGGTGGSAGLIG---------------------------------
MMAR_2113|M.marinum_M SGGTQSGGTGGSAGLIG---------------------------------
Mb2622|M.bovis_AF2122/97 TAG-VAGGAGGSAGLIG---------------------------------
Rv2591|M.tuberculosis_H37Rv TAG-VAGGAGGSAGLIG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------
MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP
TH_3810|M.thermoresistible__bu GESHTPGVYTDRQ-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GTSTSAGGSAAVGGNAG---------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PETALARGAALAAANAP---------------------------------
MUL_1718|M.ulcerans_Agy99 -----------------NGGNGGNGFLGGAGGAAGSGG------------
MMAR_2113|M.marinum_M -----------------NGGNGGNGFLGGAGGAAGSGG------------
Mb2622|M.bovis_AF2122/97 -----------------NGGNGGAGGAGAAGGAGGAGG------------
Rv2591|M.tuberculosis_H37Rv -----------------NGGNGGAGGAGAAGGAGGAGG------------
Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGAGGAGGTGG-TGGAGGTGG------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGNGGNGGTGG-TGGNGGTGG------------
MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS
TH_3810|M.thermoresistible__bu ------------------GEDGEDGTGTGIGGRGGNGG------------
MAB_4284c|M.abscessus_ATCC_199 ----------------LAGNAGLAGNAGLAGNAGLAGN------------
MLBr_01183|M.leprae_Br4923 -------------------------MPLFLNAEPQALT------------
MAV_4827|M.avium_104 ----------------LFASSTAALAYAQDPGTGAVDQYS----------
MUL_1718|M.ulcerans_Agy99 ----WLAGSGGNGGAGGS--VTGVGEVGGAGGAGGSAPLLGWGGNGGAGG
MMAR_2113|M.marinum_M ----WLAGSGGNGGAGGS--VTGVGEVGGAGGAGGSAPLLGWGGNGGAGG
Mb2622|M.bovis_AF2122/97 ----WLLGNGGAGGPGGP--TDVPAGTGGAGGAGGDAPLIGWGGNGGPGG
Rv2591|M.tuberculosis_H37Rv ----WLLGNGGAGGPGGP--TDVPAGTGGAGGAGGDAPLIGWGGNGGPGG
Mflv_5091|M.gilvum_PYR-GCK -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGHGG
TH_3810|M.thermoresistible__bu ----SSSGTHPMAEDG--------EHVKALDGRPGLD-----GGNGSHGG
MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG
MLBr_01183|M.leprae_Br4923 ------AAANTLEGLS-------AATVASNAAAAQLT-----TEIAPPAA
MAV_4827|M.avium_104 --LPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRR
. . .
MUL_1718|M.ulcerans_Agy99 DSTQG-TGGRGGAGGAGG---ALAAIGGAGGAGGTGA--------TAGGD
MMAR_2113|M.marinum_M DSTQG-AGGMGGAGGAGG---ALASIGGAGGAGGTGT--------TSGGD
Mb2622|M.bovis_AF2122/97 FAAFG-NGGAGGNGGASG---SLFGVGGAGGVGGSSE--------DVGGT
Rv2591|M.tuberculosis_H37Rv FAAFG-NGGAGGNGGASG---SLFGVGGAGGVGGSSE--------DVGGT
Mflv_5091|M.gilvum_PYR-GCK TGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGT
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGT
MSMEG_0868|M.smegmatis_MC2_155 DGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGN
TH_3810|M.thermoresistible__bu NGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDAD
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNA
MLBr_01183|M.leprae_Br4923 DDVSILLAHFFSGHGR--------QYQAHASQGATN---------HQDLI
MAV_4827|M.avium_104 RPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTE
. . .
MUL_1718|M.ulcerans_Agy99 GGVGGEG-------------SGRLFGLGG---------------------
MMAR_2113|M.marinum_M GGVGGEG-------------SGRLFGLGG---------------------
Mb2622|M.bovis_AF2122/97 GGAGGAG-------------RGLFLGLGG---------------------
Rv2591|M.tuberculosis_H37Rv GGAGGAG-------------RGLFLGLGG---------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-----
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-----
MSMEG_0868|M.smegmatis_MC2_155 GGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIR
TH_3810|M.thermoresistible__bu GGNGGDG---------------GNGGSAG---------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAG-------------LAGNAGLAG---------------------
MLBr_01183|M.leprae_Br4923 QSLLTSS-----------------SAYAG---------------------
MAV_4827|M.avium_104 QAPAPPP-------------VQASAPQPK---------------------
MUL_1718|M.ulcerans_Agy99 ------------AGGAGGTGTTSGGVGG----------------------
MMAR_2113|M.marinum_M ------------AGGAGGTGITSGGVGGDG--------------------
Mb2622|M.bovis_AF2122/97 ------------DGGAGGTSNNNGGDGGAG--------------------
Rv2591|M.tuberculosis_H37Rv ------------DGGAGGTSNNNGGDGGAG--------------------
Mflv_5091|M.gilvum_PYR-GCK ------------TGGTGGQGG-LGGGGGTG--------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------TGGTGGQGG-LGGVGGTG--------------------
MSMEG_0868|M.smegmatis_MC2_155 ATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGT
TH_3810|M.thermoresistible__bu ------------RGGTGGLRGVFGINGGNG--------------------
MAB_4284c|M.abscessus_ATCC_199 ------------NAAVAGNAAVAGNAAVAG--------------------
MLBr_01183|M.leprae_Br4923 -------------TETANHDSL----------------------------
MAV_4827|M.avium_104 ------ISVPEPVAAPKPLSPPVAAPLPAAP-------------------
MUL_1718|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2113|M.marinum_M ----GAGGGLLFGLGGSGGAGGVATDA----------TGIGGTGGAGGES
Mb2622|M.bovis_AF2122/97 ----GTAGGRLFSLGGDGGNGGAGTAI----------GSNAGDGGAGGDS
Rv2591|M.tuberculosis_H37Rv ----GTAGGRLFSLGGDGGNGGAGTAI----------GSNAGDGGAGGDS
Mflv_5091|M.gilvum_PYR-GCK ---GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLG
Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLG
MSMEG_0868|M.smegmatis_MC2_155 ATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLG
TH_3810|M.thermoresistible__bu ----RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGG
MAB_4284c|M.abscessus_ATCC_199 ----NAAVGGVLNTGVSGAIGGSSHVG---------GAINESLGGSGSVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPPQ
MUL_1718|M.ulcerans_Agy99 -----------------------TGGAGG---------------------
MMAR_2113|M.marinum_M GVIIGYAQSGAGGIGGYGGDIGGTGGAGG---------------------
Mb2622|M.bovis_AF2122/97 SALIGYAQGGSGGLGGFGESTGGDGGLGG---------------------
Rv2591|M.tuberculosis_H37Rv SALIGYAQGGSGGLGGFGESTGGDGGLGG---------------------
Mflv_5091|M.gilvum_PYR-GCK GFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSG
Mvan_1264|M.vanbaalenii_PYR-1 GFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSG
MSMEG_0868|M.smegmatis_MC2_155 GNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSG
TH_3810|M.thermoresistible__bu GTPSAGFGVPTTIQFPAGSCTSRAVSREG---------------------
MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTGVGGGVSTGVGVGSHVGG--------------------G
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LLAPPRLSVPQPVQPPVRVPQPPSPPQVG---------------------
MUL_1718|M.ulcerans_Agy99 VAGVLVGAGVGGFGGMGG-AGTTGGAGDVG-------------GQGVTLT
MMAR_2113|M.marinum_M VAGVLVGAGVGGFGGMGG-AGTTGGAGGVG-------------GQGVTLT
Mb2622|M.bovis_AF2122/97 AGAVLIGTGVGGFGGLGGGSNGTGGAGGAG-------------GTGATLI
Rv2591|M.tuberculosis_H37Rv AGAVLIGTGVGGFGGLGGGSNGTGGAGGAG-------------GTGATLI
Mflv_5091|M.gilvum_PYR-GCK SAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGK
Mvan_1264|M.vanbaalenii_PYR-1 SAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGA
MSMEG_0868|M.smegmatis_MC2_155 YGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTAT
TH_3810|M.thermoresistible__bu ---IMPSSRAASARAG---------------------------AACASST
MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -GTVPQSPPQHQTPPGEGTPPKPDGPGNYG---------------GGHVP
MUL_1718|M.ulcerans_Agy99 GLGVGGIGGVG-------------------GFGTATG----GDGGAGGQG
MMAR_2113|M.marinum_M GLGVGGIGGVG-------------------GFGTATG----GDGGAGGQG
Mb2622|M.bovis_AF2122/97 GLGAGGGGSIG-------------------GFAVNVGNGVGGLGGQGGQG
Rv2591|M.tuberculosis_H37Rv GLGAGGGGGIG-------------------GFAVNVGNGVGGLGGQGGQG
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQG
Mvan_1264|M.vanbaalenii_PYR-1 QGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQG
MSMEG_0868|M.smegmatis_MC2_155 GGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKG
TH_3810|M.thermoresistible__bu SRSRRSFCCSRA--------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSHV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TPGAGGSGGSG-------------------GGHVPTPGAGGSGGSGGGHV
MUL_1718|M.ulcerans_Agy99 AALWGAGFGGDGAVG---GNSFVGAGGNGGDGGNGGGLFNIGRGGDGG--
MMAR_2113|M.marinum_M AALWGAGFGGDGAVG---GNSFVGAGGNGGDGGNGGGLFNIGRGGDGG--
Mb2622|M.bovis_AF2122/97 AALIGLGAGGAGGAG---GATVVGLGGNDGDGGDGGGLFSIGVGGDGG--
Rv2591|M.tuberculosis_H37Rv AALIGLGAGGAGGAG---GATVVGLGGNGGDGGDGGGLFSIGVGGDGG--
Mflv_5091|M.gilvum_PYR-GCK AAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG--
Mvan_1264|M.vanbaalenii_PYR-1 AAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG--
MSMEG_0868|M.smegmatis_MC2_155 ADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PTPGTGGPGGTGGSG---GGHVPTPGAGTPGGSGGGHLPFPGAGSTPG--
MUL_1718|M.ulcerans_Agy99 ---------NGGNAGATGGNGGN---IGVVANGTFTQTLFGDGGNGGNGG
MMAR_2113|M.marinum_M ---------NGGNAGATGGNGGNGGNIGVVANGTFTQTLFGDGGNGGNGG
Mb2622|M.bovis_AF2122/97 ---------NAGN-GAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGV
Rv2591|M.tuberculosis_H37Rv ---------NAGN-GAMPANGGNGGNAGVIANGSFAPSFVGFGGNGGNGV
Mflv_5091|M.gilvum_PYR-GCK ---------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGA
Mvan_1264|M.vanbaalenii_PYR-1 ---------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGT
MSMEG_0868|M.smegmatis_MC2_155 SVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------GSGGGHLPTPGAGTPGGGLGGFGGGHAPAPGGGLGGGGGH
MUL_1718|M.ulcerans_Agy99 NGGTGGTPGTGGSGGILIGADGTNGS------
MMAR_2113|M.marinum_M TGGTPGTGGTGGSGGILIGADGTNGS------
Mb2622|M.bovis_AF2122/97 NGGTG---GTGGSGGILFGANGANGPS-----
Rv2591|M.tuberculosis_H37Rv NG------GTGGSGGILFGANGANGPS-----
Mflv_5091|M.gilvum_PYR-GCK GGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu --------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGTGFEAQGHAQGHASETAHTTLPGAEHH---
MLBr_01183|M.leprae_Br4923 --------------------------------
MAV_4827|M.avium_104 APAPGGGLGGFGGGHSGGGLGGLGGGHK----