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MSFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQSYQAVSAQAA AFHDRFVQLLNAGGGSYASAEIANAQQNLLNAVNAPTQTLLGRPLVGDGADGASGPVGQPGGDGGILWGN GGNGGDSTSPGVAGGAGGSAGLIGNGGRGGNGAPGGAGGNGGLGGLLLGNGGAGGVGGTGDNGVGDLGAG GGGGDGGLGGRAGLIGHGGAGGNGGDGGHGGSGKAGGSGGSGGFGQFGGAGGLLYGNGGAAGSGGNGGDA GTGVSSDGFAGLGGSGGRGGDAGLIGVGGGGGNGGDPGLGARLFQVGSRGGDGGVGGWLYGDGGGGGDGG NGGLPFIGSTNAGNGGSARLIGNGGAGGSGGSGAPGSVSSGGVGGAGNPGGSGGNGGVWYGNGGAGGAAG QGGPGMNTTSPGGPGGVGGHGGTAILFGDGGAGGAGAAGGPGTPDGAAGPGGSGGTGGLLFGVPGPSGPD G
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2125c | PE_PGRS36 | - | 100% (491) | hypothetical protein Mb2125c |
| M. bovis AF2122 / 97 | Mb0545 | PE_PGRS6a | e-143 | 50.43% (585) | hypothetical protein Mb0545 |
| M. bovis AF2122 / 97 | Mb2186c | PE_PGRS38 | e-143 | 55.07% (523) | hypothetical protein Mb2186c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-88 | 43.17% (498) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv2162c | PE_PGRS38 | 1e-142 | 56.49% (501) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 41.30% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 9e-44 | 39.34% (366) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1208 | - | 1e-140 | 55.23% (507) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 6e-24 | 40.76% (184) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-68 | 41.61% (423) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-39 | 40.26% (303) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3292 | - | 1e-135 | 51.34% (559) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-86 | 43.00% (500) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mb2125c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv --------------------MSFVIAAPEVMAAAATDLANIG--------
MMAR_1208|M.marinum_M --------------------MAFVLVAPEMVTAAASDLANIG--------
MUL_3292|M.ulcerans_Agy99 --------------------MSYVIAAPEMLAGAATDLAGIG--------
Mb2125c|M.bovis_AF2122/97 --------------------MSFVIASPEALLAAATDLAAIR--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------MSIIDFILNLFRDPVEAASYVADPEAALANAG-
MAV_4827|M.avium_104 ----------------------MNIVLGVSMAPSSIQMVVLEGEYADG--
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv -------------------------------------SSISAASAAAAGP
MMAR_1208|M.marinum_M -------------------------------------SAINTANTAVAAP
MUL_3292|M.ulcerans_Agy99 -------------------------------------AALQSANGAAAAP
Mb2125c|M.bovis_AF2122/97 -------------------------------------STIRAANAAAAVP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------LSAVSAAQVGAVMP
MAV_4827|M.avium_104 -------------------------------------ATVEEDAIDVTG-
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv --------------------------------------TMGILAAGADEV
MMAR_1208|M.marinum_M --------------------------------------TAELLAAGTDEV
MUL_3292|M.ulcerans_Agy99 --------------------------------------ITGVLAAGADEI
Mb2125c|M.bovis_AF2122/97 --------------------------------------TTGALAPAADEV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------VVAESVASNYGYQ
MAV_4827|M.avium_104 --------------------------------------ADDAATASAPDR
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv S---------------------VAISALFG-------SHAQGYQTLSAQL
MMAR_1208|M.marinum_M S---------------------EAIASLFS-------GHALDYQSLGARM
MUL_3292|M.ulcerans_Agy99 S---------------------AAVAALFS-------GHALDYQALSTQM
Mb2125c|M.bovis_AF2122/97 S---------------------AGIAALFG-------AQAQSYQAVSAQA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SQWVNTG---------------NPIHDLSGNLQNYYAAQPDGPSILSPSL
MAV_4827|M.avium_104 -----------------------VISAILG----TREGAADAGLQLSSIG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGG-----------NGGNGGLFGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGG-----------NGGNAGLFGG
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGG-----------NGGNAGLFG-
TH_3810|M.thermoresistible__bu -----------------------VDGDGG-----------SGGRTGLFSK
Rv2162c|M.tuberculosis_H37Rv AAYHNQFVRALNAGAGSYASAEAANVQ------QTLLNAINAPTQTLLGR
MMAR_1208|M.marinum_M TAFHDQFVAALTAGGGLYSSAEAAAATPL----QDLLNVVNAPTQALLGR
MUL_3292|M.ulcerans_Agy99 AGFHQQFVTALNSAGASYAAAEAASANPLQAVEQQLLGVINAPTQALLGR
Mb2125c|M.bovis_AF2122/97 AAFHDRFVQLLNAGGGSYASAEIANAQ------QNLLNAVNAPTQTLLGR
MLBr_01183|M.leprae_Br4923 -------MPLFLNAEPQALTAAANTLEG-------------LSAATVASN
MAB_4284c|M.abscessus_ATCC_199 LSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGD
MAV_4827|M.avium_104 VTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTA
Mflv_5091|M.gilvum_PYR-GCK --NGGNGGNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG-
Mvan_1264|M.vanbaalenii_PYR-1 --NGGNGGNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG-
MSMEG_0868|M.smegmatis_MC2_155 --NGGNGGVGWAGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDG
TH_3810|M.thermoresistible__bu LSRGGDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYR--------
Rv2162c|M.tuberculosis_H37Rv -PLIGNGADG---GPGQNGGPGG--LLYGNGGNGGAG-------------
MMAR_1208|M.marinum_M -PLIGDGADGT--APGQAGGAGG--LLYGNGGNGAAG-------------
MUL_3292|M.ulcerans_Agy99 -PLIGDGTAG---APGQNGGDGG--LLWGNGGAGGVG-------------
Mb2125c|M.bovis_AF2122/97 -PLVGDGADGASGPVGQPGGDGG--ILWGNGGNGGDS-------------
MLBr_01183|M.leprae_Br4923 --AAAAQLTTEIAPPAADDVSILLAHFFS--GHGRQY-------------
MAB_4284c|M.abscessus_ATCC_199 LQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNG-------------
MAV_4827|M.avium_104 VLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAG-----------
.
Mflv_5091|M.gilvum_PYR-GCK -APGVAGATGATGVTSGVVGGNGEDAVGYGATGAAGAA-GAAGAAGAAG-
Mvan_1264|M.vanbaalenii_PYR-1 -APGVAGATGATGVTSNVTGGNGADAVGYGATGAAGAA-GAAGAAGKAG-
MSMEG_0868|M.smegmatis_MC2_155 GTGGTGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAA-GAAGNGGDGGN
TH_3810|M.thermoresistible__bu --------TTDNNALDGGHGGNGGNVGFFSLFNLGGAG-GWGGSGVDG--
Rv2162c|M.tuberculosis_H37Rv -------------DTANPNGGNGGSAGLIGNGGAGGAG-AATGAGGAGG-
MMAR_1208|M.marinum_M -------------TNPGVAGGAGGAAGLIGNGGAGGIG-GAGGSGGAGG-
MUL_3292|M.ulcerans_Agy99 -------------TAAHPTGGSGGSAGLIGTGGAGGAGYGPAAQTGATG-
Mb2125c|M.bovis_AF2122/97 -------------TSPGVAGGAGGSAGLIGNGGRGGNG-APGGAGGNGG-
MLBr_01183|M.leprae_Br4923 --------------QAHASQGATNHQDLIQSLLTSSSA--YAGTETANH-
MAB_4284c|M.abscessus_ATCC_199 ----------DVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADI
MAV_4827|M.avium_104 -------------QLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQT
.
Mflv_5091|M.gilvum_PYR-GCK -------------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--
Mvan_1264|M.vanbaalenii_PYR-1 -------------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--
MSMEG_0868|M.smegmatis_MC2_155 GGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGG
TH_3810|M.thermoresistible__bu --------------VDVVGGNPDGGTPGAHG--ESHTPGVYTDR------
Rv2162c|M.tuberculosis_H37Rv ---------------NGGWLYGNGGPGGAAG---LGTAGGVSPAG-----
MMAR_1208|M.marinum_M ---------------TGGWLYGNGGAGGAGG---AGAPGLVSFNGSNGG-
MUL_3292|M.ulcerans_Agy99 ---------------GSGGVGGTGGSGLDGPD--SGAAGGAGGSG-----
Mb2125c|M.bovis_AF2122/97 ---------------LGGLLLGNGGAGGVGG---TGDNG-VGDLG-----
MLBr_01183|M.leprae_Br4923 -----------------DSL------------------------------
MAB_4284c|M.abscessus_ATCC_199 DKS--------VTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIG-
MAV_4827|M.avium_104 ------------TTFLDVSVAEEPETALARGAALAAANAPLFASS-----
Mflv_5091|M.gilvum_PYR-GCK --------------AVGAAGAAG------TVGTAGATGGTG---------
Mvan_1264|M.vanbaalenii_PYR-1 --------------AIGTAGVAG------AAGTAGATGGTG---------
MSMEG_0868|M.smegmatis_MC2_155 AILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mb2125c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLGE
Mvan_1264|M.vanbaalenii_PYR-1 ------VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAGE
MSMEG_0868|M.smegmatis_MC2_155 TAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGI
TH_3810|M.thermoresistible__bu ------QGEDGEDGTGTGIGGRGGNG------------------------
Rv2162c|M.tuberculosis_H37Rv --------GAGGAAGLWGHGGAGGAGG-----------------------
MMAR_1208|M.marinum_M ------NGGNGGAAGWWGTGGAGGAGGE----------------------
MUL_3292|M.ulcerans_Agy99 --------GSGGAARLFGNGGAGGSGGK----------------------
Mb2125c|M.bovis_AF2122/97 ---------AGGGG---GDGGLGGRAG-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------SHNQANIGTSTSAGGSAAVGGN----------------------
MAV_4827|M.avium_104 -------TAALAYAQDPGTGAVDQYSLP----------------------
Mflv_5091|M.gilvum_PYR-GCK TGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQG
Mvan_1264|M.vanbaalenii_PYR-1 TGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQG
MSMEG_0868|M.smegmatis_MC2_155 DGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQA
TH_3810|M.thermoresistible__bu ------------------------------GSSSGTHPMAEDG-------
Rv2162c|M.tuberculosis_H37Rv ----------------SASGAPG---------AGGAGGDGGRGG------
MMAR_1208|M.marinum_M --------------GGAAGGDPAGIAYGSTGGVGGNGGSGGNGG------
MUL_3292|M.ulcerans_Agy99 --------------GGNGGSAIET-------GNDGAAGAGGHGG------
Mb2125c|M.bovis_AF2122/97 --------------------------------LIGHGGAGGNG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------AGLAGNAGLAGNAGLAGNAGLAGNAG------
MAV_4827|M.avium_104 -----------------------------DYLYVPVDPEPGDDE------
Mflv_5091|M.gilvum_PYR-GCK GQG-------------LQGGKGGDGGAGGKGGDADSMGS-----------
Mvan_1264|M.vanbaalenii_PYR-1 GQG-------------LQGGQGGDGGTGGTGGDATSMGE-----------
MSMEG_0868|M.smegmatis_MC2_155 GYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTA
TH_3810|M.thermoresistible__bu -----------------EHVKALDGRPGLDGG------------------
Rv2162c|M.tuberculosis_H37Rv -------------LLYGDGGAGGAGGNGSNG-------------------
MMAR_1208|M.marinum_M -------------WFAGNAGAGGNGGVGGDGNAA----------------
MUL_3292|M.ulcerans_Agy99 -------------WLVGNGGIGGDGGSGGVGGDAGAYGP-----------
Mb2125c|M.bovis_AF2122/97 ----------------GDGGHGGSGKAGGSG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------LAGNAGLAGNAGLAGNAGLAG---------------
MAV_4827|M.avium_104 ---------------LAYSAVGEEDAESPTVVIEKLFLP-----------
Mflv_5091|M.gilvum_PYR-GCK -------AGATGGKGGNGGNGGRGGLFG---------------KGGNAGN
Mvan_1264|M.vanbaalenii_PYR-1 -------AGATGGKGGNGGNGGRGSLFG---------------RGGNAGN
MSMEG_0868|M.smegmatis_MC2_155 IGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGN
TH_3810|M.thermoresistible__bu ----------NGSHGGNGGHGGRGGFLG----------------------
Rv2162c|M.tuberculosis_H37Rv ------------VTGVHGGNGGAGGAAG----------------------
MMAR_1208|M.marinum_M ---------DSGLVGGAGGVGGAGGAAG----------------------
MUL_3292|M.ulcerans_Agy99 --------PANGGAGGHGGMGGVGGDAGL---------------------
Mb2125c|M.bovis_AF2122/97 ---------------GSGGFGQFGGAGGL---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------NAGLAGNAGLAGNAGLAGN---------------------
MAV_4827|M.avium_104 -------EDSEPRRRPVLLVGSGLAVVGIS--------------------
Mflv_5091|M.gilvum_PYR-GCK GAD----------------------GGTGGAGGAGGTGG-TGGAGGTGG-
Mvan_1264|M.vanbaalenii_PYR-1 GGN----------------------GGTGGNGGNGGTGG-TGGNGGTGG-
MSMEG_0868|M.smegmatis_MC2_155 GGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAG
TH_3810|M.thermoresistible__bu ------------------------IGGSGGWGGHGGNGGDTDADGGNGG-
Rv2162c|M.tuberculosis_H37Rv ------------------------LIGNGGAGGDGGNGGLSNTGAS----
MMAR_1208|M.marinum_M ------------------------LFGDGGAGGQGGDGAVSDALAASHGG
MUL_3292|M.ulcerans_Agy99 ------------------------LFGSGGAGGVGGNGAIGGTGVMS---
Mb2125c|M.bovis_AF2122/97 ------------------------LYGNGGAAGSGGNGGDAGTGVSS---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------AGLAGNAGLAGNAGLAGNAGLAGNA
MAV_4827|M.avium_104 ---------------------AVLALEIALAIGIRTTGTVALQPTPNQHL
Mflv_5091|M.gilvum_PYR-GCK ----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 ----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG--
MSMEG_0868|M.smegmatis_MC2_155 ASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE-
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv -------------------GGAGGAGG-----AALIGNGGDGGHG-----
MMAR_1208|M.marinum_M TG--GDGGRSGWLSGNAGAGGAGGAGGSTNGIGNFAGNGGAGGNGGA---
MUL_3292|M.ulcerans_Agy99 -----------------GAGGAGGDGGN-GGYAQLIGDGGGGGAGGAGYS
Mb2125c|M.bovis_AF2122/97 --------------------------------DGFAGLGGSGGRG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G---------------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG-
MAV_4827|M.avium_104 IVP----------------TEQAPAPPPVQASAPQPKISVPEPVAAPKPL
Mflv_5091|M.gilvum_PYR-GCK ----GTGGTGGTGGTGGKG-------GTGGTGGAGGTG----GDGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGTGGKG-------GTGGTGGDGGTG----GTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 ----GEGGTGGHGGDGGRG-------GDGALGGNGGTGGVGLGNGGKGGN
TH_3810|M.thermoresistible__bu --------DGGNGGSAGRG-------GTGGLRGVFGIN------------
Rv2162c|M.tuberculosis_H37Rv -------GNGGHGNSGGAG-------GAGGAGGAGGAG------------
MMAR_1208|M.marinum_M ---AGLFGNGAAGGAGGAGGASQTFTGAGGAGGTGGAGGWLYGNGGAGGA
MUL_3292|M.ulcerans_Agy99 ASGLPPAGIGAPGGAGGAGGSGGWLVGNGGAGGIGGIG----------AS
Mb2125c|M.bovis_AF2122/97 --------------------------GDAGLIGVGGGG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------NAAVAGNAAVAG--NAAVAGNAAVGGVLNTG------------
MAV_4827|M.avium_104 SPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVP-----------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTG-------------------GTGGTGGTGGAG-----------D
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTG-------------------GTGGTGGTGGAG-----------D
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGTYVDPSHT----------GAGGNGGNGGAGRIRVNNGTATGT
TH_3810|M.thermoresistible__bu -------------------------------GGNGRAG------------
Rv2162c|M.tuberculosis_H37Rv GHVG-----------------------LIGNGGNGGAG------------
MMAR_1208|M.marinum_M GGVGGAGIGTGGLGSNGGNGGTGGIGGLIGNGGAGGAGG-----------
MUL_3292|M.ulcerans_Agy99 GSFG----------------------APSGQGGNGGIGG-----------
Mb2125c|M.bovis_AF2122/97 -----------------------------GNGGDPGLG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------VSGAIGGSSHVGG-----------
MAV_4827|M.avium_104 ---------------------PVPVPVPVRIPVPDPVSP-----------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGG----TGGQGGQGGQGG-----------------TGGTGGQ
Mvan_1264|M.vanbaalenii_PYR-1 GLGGTGGTGG----TGGFGGQGGQGG-----------------TGGTGGQ
MSMEG_0868|M.smegmatis_MC2_155 ATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGN
TH_3810|M.thermoresistible__bu -----------------LGGRGXXXX-----------------GGGVG--
Rv2162c|M.tuberculosis_H37Rv -------------------GNGGNDNSSTLAD-----------AGSGG--
MMAR_1208|M.marinum_M ----AGSASGPSGYSGGNGGNGGNGGAAQLIG-----------AGGGGGV
MUL_3292|M.ulcerans_Agy99 ----AAGLFG----QGGAGGNGGQGGGDDFAL-----------SGGAGG-
Mb2125c|M.bovis_AF2122/97 ---------------------------ARLFQ-----------VGSRGG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------AINESLGGSGSVGGSTAVGG--------GAHTGVGGGV
MAV_4827|M.avium_104 --------------PQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQ
Mflv_5091|M.gilvum_PYR-GCK GG-LGGGGGTG-----------------------GQGGTGGTGGQGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GG-LGGVGGTG-----------------------GTGGTGGTGGQGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M AGVGGAGGTGAAAGV---------------TGSAGASGVGGRLYSGNGIP
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mb2125c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STGVG---------------------------------------------
MAV_4827|M.avium_104 SP------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGG------
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGG------
MSMEG_0868|M.smegmatis_MC2_155 QGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTAN------
TH_3810|M.thermoresistible__bu -----------------AAVRSGNGVFSGGGGTPSAGFGVPTTI------
Rv2162c|M.tuberculosis_H37Rv -----------------AGAAGGNG--GLFYGNGG---------------
MMAR_1208|M.marinum_M DIFGRPLIGDGADGAPGTGQAGGDG--GWLYGNGGNGGSGAAGQAGGAGG
MUL_3292|M.ulcerans_Agy99 -----------------AGGAGGHG--GQLYGDGGGGG------------
Mb2125c|M.bovis_AF2122/97 --------------------DGGVG--GWLYGDGGG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------VGSHVGGGISESLGGSGSVGGSTAVGG------
MAV_4827|M.avium_104 ---------------PQHQTPPGEGTPPKPDGPGNYGGGHVPTP------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1208|M.marinum_M AAGLIGNGGAGGTGGSGAAGGNGGAGGWLFGNGGNGGTGGDAVAGLPGLN
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mb2125c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------LGGPGG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------QGGPGG
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------AANPGS
TH_3810|M.thermoresistible__bu --------------------------------------------QFPAGS
Rv2162c|M.tuberculosis_H37Rv --------------------------------------------VGGRGG
MMAR_1208|M.marinum_M GGNGGNGGAGGAAGWWGHGGIGGQGGTGGAAGGFANTAPSTNGLLGGNGG
MUL_3292|M.ulcerans_Agy99 --------------------------------------------AGGMGG
Mb2125c|M.bovis_AF2122/97 ---------------------------------------------GGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------GAHTG
MAV_4827|M.avium_104 ----------------------------------------------GAGG
Mflv_5091|M.gilvum_PYR-GCK STGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGA
Mvan_1264|M.vanbaalenii_PYR-1 STGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGA
MSMEG_0868|M.smegmatis_MC2_155 ATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGG
TH_3810|M.thermoresistible__bu CTSRAVSREGIMPSSRAAS--------------ARAGAACASSTSRSRRS
Rv2162c|M.tuberculosis_H37Rv NGGFSSAG--------------------------TSGGDGGIGGAGGIGG
MMAR_1208|M.marinum_M NGGDGGAGGWLFGDAGAGGQGGTGGAANDPLVGGSTGGSGGAGGNGGTAG
MUL_3292|M.ulcerans_Agy99 SVDIAESG--------------------------VTGGRGGSGSVGGGAG
Mb2125c|M.bovis_AF2122/97 NGGLPFIG-------------------------------STNAGNGGSAR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGVSTGVG-------------------------VGSHVGGGISESLGG
MAV_4827|M.avium_104 SGGSGGGHVP------------------------TPGAGGSGGSGGGHVP
Mflv_5091|M.gilvum_PYR-GCK QGATGAQGATG------AQGATG-ATGAAG-----KAGATGAAGAAGAAG
Mvan_1264|M.vanbaalenii_PYR-1 QGATGAQGATG------AQGATG-ATGASG-----AQGSAGSAGSAGVAG
MSMEG_0868|M.smegmatis_MC2_155 EASNGGVAGNGGNALVMAAGTTGVATGNTA-----TGGDGGAATTAGATG
TH_3810|M.thermoresistible__bu FCCSRA--------------------------------------------
Rv2162c|M.tuberculosis_H37Rv LIGSGGGGGDG--------------------------GNGGQAPTPGN--
MMAR_1208|M.marinum_M LFGAGGAGGTGGTAGAGIAVGSNGGHGGQGGYGGWLGGSGGAGGTGGTGG
MUL_3292|M.ulcerans_Agy99 LWGAGGQGGDGAQ-----------------------GGDGGAGVDTTTG-
Mb2125c|M.bovis_AF2122/97 LIGNGGAGGSGGS------------------------GAPGSVSSGGVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SGSVGGSTAVG--------------------------GGAHTGVGGGVNT
MAV_4827|M.avium_104 TPGTGGPGGTG-------------------------GSGGGHVPTPGAG-
Mflv_5091|M.gilvum_PYR-GCK SAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGAT
Mvan_1264|M.vanbaalenii_PYR-1 SAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGAT
MSMEG_0868|M.smegmatis_MC2_155 GAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPV
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv ------------------AGDGGAGG----NARLIGDGG-----------
MMAR_1208|M.marinum_M SGD----------IYAGAGGTGGSGG----AARLFGTGG-----------
MUL_3292|M.ulcerans_Agy99 -----------------AGGDGGAGAGGGTSGFLYGNGG-----------
Mb2125c|M.bovis_AF2122/97 -----------------AGNPGGSGG---NGGVWYGNGG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVG---------------VGSHVGGGISESLGGSGSVGG-----------
MAV_4827|M.avium_104 -------------------TPGGSGG----GHLPFPGAG-----------
Mflv_5091|M.gilvum_PYR-GCK G--------AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEG
Mvan_1264|M.vanbaalenii_PYR-1 G--------AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEG
MSMEG_0868|M.smegmatis_MC2_155 GSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEH
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv ---------RGGNGGEGG--DGPPGVKGDGGNGGN----------GGNA-
MMAR_1208|M.marinum_M ---------TGGAGGVGG--ASDFQFAGSGGSGGT----------GGAAG
MUL_3292|M.ulcerans_Agy99 ---------AGGAGGHGG--GGP-GMGGDGGDGGD----------GGRA-
Mb2125c|M.bovis_AF2122/97 ---------AGGAAGQGGPGMNTTSPGGPGGVGGH----------GGTA-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------STAVGGGAHTSAINDALGGSGSVGGS--------TAVGGGA
MAV_4827|M.avium_104 ----------STPGGSGGGHLPTPGAGTPGGGLGG----------FGGGH
Mflv_5091|M.gilvum_PYR-GCK GEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGS
Mvan_1264|M.vanbaalenii_PYR-1 GEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGS
MSMEG_0868|M.smegmatis_MC2_155 NTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv VVIGNGGNGGAGG-----------FGIPVGSGGAGGSRGVLFGTPGANGA
MMAR_1208|M.marinum_M WLIGNGGSGGQGGLAGTADPVTGLFGGTGGAGGAGGAAGWLYGAGGSGGA
MUL_3292|M.ulcerans_Agy99 QLIGTGGNGGAGG--------TAAPGGTDGTAGAAGKGGVLFGTDGATG-
Mb2125c|M.bovis_AF2122/97 ILFGDGGAGGAGAAGG-----PGTPDGAAGPGGSGGTGGLLFGVPGPSGP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHAS
MAV_4827|M.avium_104 APAPGGGLGGGGGHAP-------APGGGLGGFGGGHSGGGLGGLGGGHK-
Mflv_5091|M.gilvum_PYR-GCK GGSGGSGGSGGAAGDSDD--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GGSGGAGGSGGAAGDSD---------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGADGTPGTAGTTGANNP--------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Rv2162c|M.tuberculosis_H37Rv DG------------------------------------------------
MMAR_1208|M.marinum_M GGAGTASVYPGLSGGNGGNGGNGGAAQVIGNGGSGGTAGTGGAGGPDDPP
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mb2125c|M.bovis_AF2122/97 DG------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ETAHTTLPGAEHH-------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_0868|M.smegmatis_MC2_155 -----------------------------
TH_3810|M.thermoresistible__bu -----------------------------
Rv2162c|M.tuberculosis_H37Rv -----------------------------
MMAR_1208|M.marinum_M NNIPAGTDGQDGAGGAGGSGGLVFGDSGG
MUL_3292|M.ulcerans_Agy99 -----------------------------
Mb2125c|M.bovis_AF2122/97 -----------------------------
MLBr_01183|M.leprae_Br4923 -----------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------
MAV_4827|M.avium_104 -----------------------------