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M. bovis AF2122 / 97 Mb1953c (PPE35a)

annotation: PPE family protein
coordinates: 2160370 - 2162247
length: 625

MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAA
PYAGWLAAAATQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAEAAY
EEMWALDVSAMAAYHSGASAVAVALPAFALPLRLPAGLAAGPAAVVTALTTAVGMPTFAGRAIAASLGLA
NVGGGNLGNANNGLGNIGNANLGNNNLGSGNFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFA
NAGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVGLFNAGSANIGFFNSGNGNFGIGNSGNFSTG
LFNPGHGNTGFLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTG
AFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAITLPSLTIPAV
TTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIPATTTPANITVGAFNLPQLSI
PSVTVPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGNHCRRIYATHDTHPVNKYTPNKYRRL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1953cPPE35a-100% (625)PPE family protein
M. bovis AF2122 / 97Mb1782cPPE240.076.37% (601) PPE family protein
M. bovis AF2122 / 97Mb1951cPPE34e-15948.07% (699) PPE family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0325-2e-2534.91% (212) PPE protein
M. tuberculosis H37RvRv1918cPPE350.0100.00% (599) PPE family protein
M. leprae Br4923MLBr_01182-1e-2839.64% (169) PPE-family protein
M. abscessus ATCC 19977MAB_0669-1e-2538.76% (178) PPE-family protein
M. marinum MMMAR_0932-0.068.11% (599) PPE family protein
M. avium 104MAV_4704-2e-4958.18% (165) PPE family protein
M. smegmatis MC2 155MSMEG_0619-2e-2634.03% (238) PPE family protein
M. thermoresistible (build 8)TH_3569-1e-2635.41% (209) PUTATIVE PPE protein
M. ulcerans Agy99MUL_0782-0.068.64% (491) PPE family protein
M. vanbaalenii PYR-1Mvan_0415-2e-2635.58% (208) PPE protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0619|M.smegmatis_MC2_155      ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE
TH_3569|M.thermoresistible__bu      ---------MMTAPIWMALPPEVHSALLSSGPGPGSLLAAASAWHALSAE
Mflv_0325|M.gilvum_PYR-GCK          MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE
Mvan_0415|M.vanbaalenii_PYR-1       ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE
MAB_0669|M.abscessus_ATCC_1997      ----------MTAPIWMAEPPEVHSALLSAGPGPGAVLAAAVQWQEIGNN
Mb1953c|M.bovis_AF2122/97           -------------MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATE
Rv1918c|M.tuberculosis_H37Rv        -------------MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATE
MMAR_0932|M.marinum_M               -------------MNFSVLPPEINSARIFAGAGSSPMLDAAAAWQGLAKE
MUL_0782|M.ulcerans_Agy99           -------------MNFSVLPPEVNSALIFTGPGAEPMRTAATAWGGMAVE
MAV_4704|M.avium_104                ----------MTNPHFAWLPPEVNSALIYSGPGPGPLLAAAAAWDGLAEE
MLBr_01182|M.leprae_Br4923          ------------MFDFAALSPETNSTRMYLGPGSSPILTAAAAWVVLAKE
                                                   :   .** :*: :  *.*. .:  *.  *  :. :

MSMEG_0619|M.smegmatis_MC2_155      YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA
TH_3569|M.thermoresistible__bu      YASAAAELSSVLANVQAGSWEGPSAERYVAAHAPYLAWLTQQSANSAATA
Mflv_0325|M.gilvum_PYR-GCK          YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA
Mvan_0415|M.vanbaalenii_PYR-1       YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA
MAB_0669|M.abscessus_ATCC_1997      YANTAVELAQVLAGVRAGSWQGPSASEYVAAHLPYLAWLEQAAAESSVIA
Mb1953c|M.bovis_AF2122/97           LASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAAPYAGWLAAAATQAEQAA
Rv1918c|M.tuberculosis_H37Rv        LASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAAPYAGWLAAAATQAEQAA
MMAR_0932|M.marinum_M               LASAADSFGSVTSGLVDGSWQGPSAAAMTAVAAPYAGWLGAVAAQAQQAA
MUL_0782|M.ulcerans_Agy99           LESAADSFASVTSGLVGGAWQGASSVAMGTAAASYLGWLNAAAAHAEQAA
MAV_4704|M.avium_104                LASSAQSFSSVTSDLASGSWQGASSAAMMTVANQYVSWLSAAAAQAEEVS
MLBr_01182|M.leprae_Br4923          LTAAAQGLQSAVEALLT-TFEGESAAALAERVTPYEKWLTQNAASAELTA
                                       :*  : .    :   :::* *:         *  **   :: .   :

MSMEG_0619|M.smegmatis_MC2_155      VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE
TH_3569|M.thermoresistible__bu      GRHETAAAAYSTALATMPTMAELTLNKTTHAVLVATNFLGINTIPIALNE
Mflv_0325|M.gilvum_PYR-GCK          VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE
Mvan_0415|M.vanbaalenii_PYR-1       AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE
MAB_0669|M.abscessus_ATCC_1997      AQHETTAAAYNSALAAMPTLAELAANHITHGVLVGTNFFGINTIPIALNE
Mb1953c|M.bovis_AF2122/97           TQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAE
Rv1918c|M.tuberculosis_H37Rv        TQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAE
MMAR_0932|M.marinum_M               GQAGAFVSEFEAVQSAMVRPALVAANRSDLVSLVLSNLFGQNAPAIAATE
MUL_0782|M.ulcerans_Agy99           AQAEALVAEFAAAQSAMVQPFLLAANRSSLVSLVLSNLFGQNAPAIEAVE
MAV_4704|M.avium_104                HQASAIATAFEVALAATVQPAVVAANRALVQALAATNWLGQNTPAIADIE
MLBr_01182|M.leprae_Br4923          TQLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKE
                                     :  . .  :  .         :  *:     *  :* :* *: .*   *

MSMEG_0619|M.smegmatis_MC2_155      ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKPGVGEAGSASA
TH_3569|M.thermoresistible__bu      ADYVRMWIQAATSMSTYQAVAGTAVMSAPASSPAPLLLAPGVSEAADAMA
Mflv_0325|M.gilvum_PYR-GCK          ADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVGEAGRAAA
Mvan_0415|M.vanbaalenii_PYR-1       ADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFVLAPGVGEAGRAAA
MAB_0669|M.abscessus_ATCC_1997      ADYVRMWVQAAATMSAYQATTEAMTSAIPPTQQPPAILSPG-GEARSDQS
Mb1953c|M.bovis_AF2122/97           AAYEEMWALDVSAMAAYHSGASAVAVALPAFALPLR----LPAGLAAG--
Rv1918c|M.tuberculosis_H37Rv        AAYEEMWALDVSAMAAYHSGASAVAVALPAFALPLR----LPAGLAAG--
MMAR_0932|M.marinum_M               SAYEEMWALDVAVMAAYHSGASTVVSALTPFTAPLANVAGVPAQAAAALM
MUL_0782|M.ulcerans_Agy99           AEYEQMWALDVSTMATYHAGASAAAASLTPLAQPLQNLSELPGRVIAAFG
MAV_4704|M.avium_104                AAYEQMWASDVAAMFGYHADASAAVAKLPPWNEVLQ--------------
MLBr_01182|M.leprae_Br4923          AEYTEMWIQDAAAMTSYQASVLEAVGATKAFTAPPLGVN-----------
                                    : * .**   .: *  *::                               

MSMEG_0619|M.smegmatis_MC2_155      SVQQMSAQATAAESGSSLDLSSIISDLLNQYLQGVPGGQ-AILDFLKDPL
TH_3569|M.thermoresistible__bu      TTQQIGSQATAADSGTALNLSDLIANLLQYYQDYLDQLFGPIVDFLRDPI
Mflv_0325|M.gilvum_PYR-GCK          DMSAFAAQPMAAQAGAAFDVSNIIADIIRLYGEVLRFLFEPIFNFLRDPI
Mvan_0415|M.vanbaalenii_PYR-1       DVTAFAAQAQAAEAGSALDLSNIIADLIRAYGELLRFLFEPIFDFLRDPL
MAB_0669|M.abscessus_ATCC_1997      DVPGSPDQ---------------IMKMLQGFQQWFEKMG--FNPATSAVL
Mb1953c|M.bovis_AF2122/97           PAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNAN
Rv1918c|M.tuberculosis_H37Rv        PAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNAN
MMAR_0932|M.marinum_M               NSAAPMVAAPAATAQLIG-----VNLGLANVGSGNVGNANNGLGNIGNGN
MUL_0782|M.ulcerans_Agy99           NGAPATTVTAAVTALRLPADASTVNFGLANIGSGNVGNANNGIGNLGSGN
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          EVGLAQEVVEEVVEEVVEEVVEAEQAISQAALDQAVNEGMEATVVPQVDQ
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      GNLGRLLTDFMTNPAGALATWWPFLFGVAYQVFFNLVGWPTWGMIFASPF
TH_3569|M.thermoresistible__bu      GNLFQLIDDFLTNPAGALVTWWPLLFAVAYQVFTNLVGWPTWAMILASPV
Mflv_0325|M.gilvum_PYR-GCK          GNTFALITDFLTNPVQALITWGPFLLAVVYQAVSWVGASILYPSLFLLPL
Mvan_0415|M.vanbaalenii_PYR-1       GNTIKLITDFLTNPAQALITWGPFLAAVAYQAVSWVGASILYPSLLLLPL
MAB_0669|M.abscessus_ATCC_1997      AVIMLFLYDLLWYPY-----YASYLLPFLIPALSGLSG-LAALMHLRPAA
Mb1953c|M.bovis_AF2122/97           LGNNNLGSGNFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFAN
Rv1918c|M.tuberculosis_H37Rv        LGNNNLGSGNFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFAN
MMAR_0932|M.marinum_M               LGNGNFGSGNLGSSNFGWANLGSNNIGVANAGGGNQGFGNIGNVNTGFGN
MUL_0782|M.ulcerans_Agy99           LGNFNLGSGNLGSSNAGWANLGSNNIGGANSGGNNLGWGNLGGLNTGFAN
MAV_4704|M.avium_104                --------------------------------------------NLGFSN
MLBr_01182|M.leprae_Br4923          QVNVDVATPQTAVPDSSSAAAPQLWGGFAQHLSPINDTLSMINNHAGMAN
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      LIPALAALGITGLVLLIDHVLNNPVDVPAEDEAPQEVAAAPRTDQPLAVG
TH_3569|M.thermoresistible__bu      LIPLAITLGVAGLVMIADQAQP-----PAEEAAPEEDVAAP---------
Mflv_0325|M.gilvum_PYR-GCK          LATTLAIVAGVGQHLLSLLNTP-PAEEAAEEPAPAQSAPSRPDQQSFPAT
Mvan_0415|M.vanbaalenii_PYR-1       VATTLAIVLGVGAYLLENLPAP-AEDAPAEEPAASSPAPTRADQPSPAIA
MAB_0669|M.abscessus_ATCC_1997      PGPVPAAALSPGDRPIRRPTQHVEPNLAALPLPTSSVVPSGG--------
Mb1953c|M.bovis_AF2122/97           AGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVGLFNAGSANIGF
Rv1918c|M.tuberculosis_H37Rv        AGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVGLFNAGSANIGF
MMAR_0932|M.marinum_M               TGIGNFGLANTGNNNIGIALTGDNQIGIGGLNSGVGNFGLFNSGTGNVGF
MUL_0782|M.ulcerans_Agy99           AGSGNFRFANTGNNNIGIGLTGDNQVGIGGLNSGVGNFGLFNSGTGNVGL
MAV_4704|M.avium_104                ASTAVTRPAGSG--AVARGYTSR---------------------------
MLBr_01182|M.leprae_Br4923          AGLSLVNGMGSAMKSLAPTTTKAAESAFKAMGSAVQSTG-----------
                                               .   :                                  

MSMEG_0619|M.smegmatis_MC2_155      ISPAG----------------VPGSAATAAAPAPAPAGTTVAAPAPAAAT
TH_3569|M.thermoresistible__bu      --------------------------VRAEPQNPLPLTXXX---------
Mflv_0325|M.gilvum_PYR-GCK          MSAPP----------------PPSGAPIAANTVSAGSPPAPGAPAAAAAT
Mvan_0415|M.vanbaalenii_PYR-1       VSAPP----------------PPSSAAATVGTVATGTAPAPGAPAAATAS
MAB_0669|M.abscessus_ATCC_1997      -----------------------SSVPVSTPTAPAHTVSSVPAPSAAISY
Mb1953c|M.bovis_AF2122/97           FNSGNGNFGIGNSGNFSTGLFNPGHGNTGFLNAGSFNTGMFDVG-NANTG
Rv1918c|M.tuberculosis_H37Rv        FNSGNGNFGIGNSGNFSTGLFNPGHGNTGFLNAGSFNTGMFDVG-NANTG
MMAR_0932|M.marinum_M               FNSGNGNFGIGNTGDFNTGVWNSGSGNSGFFNPGMFNTGVLDVG-NANTG
MUL_0782|M.ulcerans_Agy99           FNSGTGNFGIGNSGAYGTGLFNSGQANTGLLNAGSFNTGLLDVG-NANTG
MAV_4704|M.avium_104                --------------------------IAGFLAPRAPQ-------------
MLBr_01182|M.leprae_Br4923          ---------------------------RGLLGSSSGGHVTAQLGRAASIG
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      FVPYAVANRDPGEGFTPTLGNKSQVAAPASGVPAAASGVAASLASRRKRR
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          FVPYVVAGRDPYEGFSPTVRDSTGAKAPAGTIPAAASGIAASAAERRKRR
Mvan_0415|M.vanbaalenii_PYR-1       FVPYAVAGRDPGTGFSPTVRDSTSAKAPASGIPAAASGVAASAAERRKRR
MAB_0669|M.abscessus_ATCC_1997      AIPGLVP---PGVSFGPKSTEKSSESAVDTVAAVAAARGAVAAQARRRLR
Mb1953c|M.bovis_AF2122/97           SFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTGAFNIGDMNNG
Rv1918c|M.tuberculosis_H37Rv        SFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTGAFNIGDMNNG
MMAR_0932|M.marinum_M               YLNTGSYNMGSFNPGASNTGAFNIGDGNTGWFNNGDLNTGALNFGDMNNG
MUL_0782|M.ulcerans_Agy99           SLNTGSFNMGSFNPGPSNTGALNTGTANTGWFNTGSLNTGPFNIGDMNNG
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          SLRVPQTWTTASQPVTAATRALSPARVAVATES----ESAPLLGGGLPMA
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      RKKGAQIEERGYADAYMDYEE-PDEDPAPQPEPRVRASERGSDAMGFTGT
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          RRQKEEIKGRGYADAYADYEELPDDGPPEQPAPRVTASTRGAGPMGFAGT
Mvan_0415|M.vanbaalenii_PYR-1       RRQKDEIAGRAYADAYADYEPEPDDEPPVRQEPRIAATERGAGPMGFAGT
MAB_0669|M.abscessus_ATCC_1997      GKNKAEAGGR--RHEYLEETAGMGAT-ATADVPAYAATGRGTGPLGFAGT
Mb1953c|M.bovis_AF2122/97           LFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAI
Rv1918c|M.tuberculosis_H37Rv        LFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAI
MMAR_0932|M.marinum_M               LLNTGDLNNGFFYRGVGQGSLHFAITTPDLTLPPLELAGISIPAFSLPPI
MUL_0782|M.ulcerans_Agy99           LFNTGEMNNGIFYRGVGQGNFYFSITTPDLTLPPLEIPGITIPNLSLPPI
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          PMVPGGGS------GTGGVNTALRLQPRAFVMPRNPAAG-----------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      VTRHDVTAAGLTT-LTGDTFDDRPVTPMLPGTWDGDENPAPSPDDPEGGP
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          VSRGDEQAGGLTT-LAGDSFGGGPREPMLPGTWDPDATDDRHTDGRDGHD
Mvan_0415|M.vanbaalenii_PYR-1       VSRDAAQAGGLTT-LPGDPFGGGPKAPMLPGTWDPDTEPD------ERHN
MAB_0669|M.abscessus_ATCC_1997      APAAASTHVAATVRLSSD--EARQVIPMLPSTWDADGGDQN---------
Mb1953c|M.bovis_AF2122/97           TLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLP
Rv1918c|M.tuberculosis_H37Rv        TLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLP
MMAR_0932|M.marinum_M               TVPSMSIPAISTPANITVGGFDLPGITLPGLDIPAATTPADIVVGGFDLP
MUL_0782|M.ulcerans_Agy99           TMRR----------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      RR------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          GHDGKEKP------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       HHDGKDSQ------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           GLTVPSLTIPATTTPANITVGAFNLPQLSIPSVTVPPITIPAGTALGAFN
Rv1918c|M.tuberculosis_H37Rv        GLTVPSLTIPATTTPANITVGAFNLPQLSIPSVTVPPITIPAGTALGAFN
MMAR_0932|M.marinum_M               GITLPGLDIPAVTTPADIVVGGFDLPGITLPGLDIPAVTTPADIVVGGFD
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           LPTLSIPSVTVPPITIPAGNHCR---------------------------
Rv1918c|M.tuberculosis_H37Rv        LPTLSIPSVTVPPITIPAGTTVGGFTLPTIHTPLISTPQISIGGFSTPG-
MMAR_0932|M.marinum_M               LPGITLPGLDIPAVTTPADIVVGGFDLPGITLPGLDIPAVTTPADIVVGG
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0932|M.marinum_M               FDLPGITLPGLDIPAVTTPADIVVGGFDLPGITLPGLDIPAVTTPPNITV
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0932|M.marinum_M               GGFGLPEFTIPSLTIPSQALGNIAVGGFDLPQITTPPISVPPVALPEISI
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0932|M.marinum_M               PPITTPRVTVSGFTGPSISAPGWFLPTIITPTVSPIPPFNQNPVDLLLVR
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0932|M.marinum_M               DVFTNSVTTKIQLPTFIPRIVFGAYPGLPGGENGVIGELSIPGVTFGSFT
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           -------------------------------------RIYATHDTHPVNK
Rv1918c|M.tuberculosis_H37Rv        ------------IATQANSGVINLPTFSLNGITITNLVVFIPNNITALQT
MMAR_0932|M.marinum_M               LPYFTIDDPNGGNWTIPSIGLSGFTIPSTTFDPINVAAFMLPDITTPEIT
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           YTPNKYRRL-----------------------------------------
Rv1918c|M.tuberculosis_H37Rv        NMPGVFPQIGGFANTPPAFIN--TGTITVGGGQINGVGFSIGAINVTPFT
MMAR_0932|M.marinum_M               TTAITIPSIGVDEFTLPQISTPPFSTDPFTIDPIGLGGFTLPQISTPPFS
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        LPNVVIQPWSLG--------------------GISVDGFTLPEISTQEFT
MMAR_0932|M.marinum_M               TDPFTIDPIGLGGFTLPQISTPPFSTDPFTIDPIGLGGFTLPQISTPPFS
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        TPALTISPIGVGALSLPDITTQQFTTPELTIDPITLGGFTLPQLSIPAIT
MMAR_0932|M.marinum_M               TDPFTIDPIGLGGFTLPQISTPPFSTDPFTIDPIGLGGFTLPQISTPPFS
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        TPAFTIDPIALGGFTLPQIMTPEITTPPFAIDPIGLSGFTLPQVNIPEIT
MMAR_0932|M.marinum_M               TDPFTIDPIGLGGFTLPQISTPPISTDPFTIDPIAVAGFTLPQINIPAFT
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        TPEFTIQPVGLAAFTTPALTIASIHLPSTTMGGFAIPAGPGYFNSSATPS
MMAR_0932|M.marinum_M               TNEFTIAPIGIGGFTTPPITIPSIHLPSTTLAEFAIPGGPGYLNTSATPS
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1953c|M.bovis_AF2122/97           --------------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        LGFFNAGIGGNSGFGNSGSGLSGWFNTSPVGLLAGSGYQNYGGLISGFSN
MMAR_0932|M.marinum_M               SGFFNTGAGGNSGYANNGSGLSGWFNTNPAGLLGGSGYQNYGGLSSGFYN
MUL_0782|M.ulcerans_Agy99           --------------------------------------------------
MAV_4704|M.avium_104                --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_0619|M.smegmatis_MC2_155      ------------------------------------------
TH_3569|M.thermoresistible__bu      ------------------------------------------
Mflv_0325|M.gilvum_PYR-GCK          ------------------------------------------
Mvan_0415|M.vanbaalenii_PYR-1       ------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      ------------------------------------------
Mb1953c|M.bovis_AF2122/97           ------------------------------------------
Rv1918c|M.tuberculosis_H37Rv        LGSGISGFANTGTLPFAVTSLVSGLANIGNNLSGLFFQSTTP
MMAR_0932|M.marinum_M               LGSGVSGIANTGVLPFSVTSLVSGVSNIGNNLSGFFRGIW--
MUL_0782|M.ulcerans_Agy99           ------------------------------------------
MAV_4704|M.avium_104                ------------------------------------------
MLBr_01182|M.leprae_Br4923          ------------------------------------------