For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VIIELMRRVVGLAQGATAEVAVYGDRDRDLAERWCANTGNTLVRADVDQTGVGTLVVRRGHPPDPASVLG PDRLPGVRLWLYTNFHCNLCCDYCCVSSSPSTPHRELGAERIGRIVGEAARWGVRELFLTGGEPFLLPDI DTIIATCVKQLPTTVLTNGMVFKGRGRRALESLPRGLALQISLDSATPELHDAHRGAGTWVKAVAGIRLA LSLGFRVRVAATVASPAPGELTAFHDFLDGLGIAPGDQLVRPIALEGAASQGVALTRESLVPEVTVTADG VYWHPVAATDERALVTRTVEPLTPALDMVSRLFAEQWTRAAEEAALFPCA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1708 | moeX | - | 100% (330) | molybdopterin biosynthesis protein MoeX |
| M. bovis AF2122 / 97 | Mb0712 | pqqE | 1e-09 | 29.94% (157) | coenzyme PQQ synthesis protein E |
| M. bovis AF2122 / 97 | Mb3355c | moaA3 | 7e-08 | 28.99% (138) | molybdenum cofactor biosynthesis protein A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5060 | - | 1e-09 | 28.57% (175) | radical SAM domain-containing protein |
| M. tuberculosis H37Rv | Rv1681 | moeX | 0.0 | 100.00% (330) | molybdopterin biosynthesis protein MoeX |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3835c | - | 2e-10 | 32.61% (138) | coenzyme PQQ synthesis protein E PqqE |
| M. marinum M | MMAR_1021 | pqqE | 6e-11 | 30.10% (196) | coenzyme PQQ synthesis protein E, PqqE |
| M. avium 104 | MAV_4478 | - | 4e-10 | 30.63% (160) | radical SAM domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1423 | - | 2e-08 | 31.39% (137) | radical SAM domain-containing protein |
| M. thermoresistible (build 8) | TH_1901 | pqqE | 2e-11 | 30.29% (175) | PROBABLE COENZYME PQQ SYNTHESIS PROTEIN E PQQE (COENZYME PQQ |
| M. ulcerans Agy99 | MUL_0773 | pqqE | 4e-11 | 30.10% (196) | coenzyme PQQ synthesis protein E, PqqE |
| M. vanbaalenii PYR-1 | Mvan_5883 | - | 1e-134 | 67.98% (331) | radical SAM domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1021|M.marinum_M ---------MTTA--VPRLIEQFEHGLDAPICLTWELTYACNLACVHCLS
MUL_0773|M.ulcerans_Agy99 ---------MTTA--VPRLIEQFEHGLDAPICLTWELTYACNLACVHCLS
MAV_4478|M.avium_104 ---------MTTAAPVPRLIEQFEHGLDAPICLTWELTYACNLACVHCLS
MSMEG_1423|M.smegmatis_MC2_155 ---------MTSVQPVPRLVEQFERGLDAPICLTWELTYACNLACVHCLS
TH_1901|M.thermoresistible__bu ---------------VPRLIEQFEQGLDAPICLTWELTYACNLACVHCLS
Mflv_5060|M.gilvum_PYR-GCK ---------MTLAAPVPRLVDQFERGLDAPICLTWELTYACNLSCVHCLS
MAB_3835c|M.abscessus_ATCC_199 MSAPAVPRLNVAAVAAPKLVDQFEQGLDAPICLTWELTYACNLSCVHCLS
Mb1708|M.bovis_AF2122/97 -----------MIIELMRRVVGLAQGATAEVAVYGDR-------------
Rv1681|M.tuberculosis_H37Rv -----------MIIELMRRVVGLAQGATAEVAVYGDR-------------
Mvan_5883|M.vanbaalenii_PYR-1 ----------MVILDLMRLMATLADGAVGEIAVASVA-------------
: : : * . :.:
MMAR_1021|M.marinum_M SSGKRDPGELSTRQCQDIIDELERMQVFYVNIGGGEPTVRPDFWELVDYA
MUL_0773|M.ulcerans_Agy99 SSGKRDPGELSTRQCQDIIDELERMQVFYVNIGGGEPTVRPDFWELVDYA
MAV_4478|M.avium_104 SSGKRDPRELSTRQCMDIIDELERMQVFYVNIGGGEPTVRPDFWELVDYA
MSMEG_1423|M.smegmatis_MC2_155 SSGKRDPRELSTQQCKDIIDELERMQVFYVNIGGGEPTVRSDFWELVDYA
TH_1901|M.thermoresistible__bu SSGKRDPRELSTQQCKDIIDELQRMQVFYVNIGGGEPTVRSDFWELVDYA
Mflv_5060|M.gilvum_PYR-GCK SSGKRDPRELSTQQCKDIIDELERMQVFYVNIGGGEPTVRSDFWELVDYA
MAB_3835c|M.abscessus_ATCC_199 SSGKRDPRELSTQQCKDIIDELERMQVFYVNIGGGEPTVRSDFWELVDYA
Mb1708|M.bovis_AF2122/97 ------DRDLAERWCANTGNTLVRADVDQT--GVGTLVVR----------
Rv1681|M.tuberculosis_H37Rv ------DRDLAERWCANTGNTLVRADVDQT--GVGTLVVR----------
Mvan_5883|M.vanbaalenii_PYR-1 ------ERETAEKWCARSGNTVVQADLDET--GAGTLTVR----------
: : : * : : : :: . * * .**
MMAR_1021|M.marinum_M TAHHVGVKFSTNGVRINPEVAARLAASDYVDVQISLDGATAEVNDAVRGA
MUL_0773|M.ulcerans_Agy99 TAHHVGVKFSTNGVRINPEVAARLAASDCVDVQISLDGATAEVNDAVRGA
MAV_4478|M.avium_104 TAHHVGVKFSTNGVRITPEVAARLAASDYVDVQISLDGATAEVNDAVRGP
MSMEG_1423|M.smegmatis_MC2_155 TAHHVGVKFSTNGVRITPEVAAKLAASDYVDVQISLDGANAEVNDAVRGK
TH_1901|M.thermoresistible__bu TAHNVGVKFSTNGVRITPEVARRLAASDYVDVQISLDGATAEINDAVRGA
Mflv_5060|M.gilvum_PYR-GCK TEHHVGVKFSTNGVRIDKTVAAKLAASDYVDVQISLDGATAEVNDAVRGP
MAB_3835c|M.abscessus_ATCC_199 TEHHVGVKFSTNGVRITEEVAARLAASDYVDVQISLDGATAEVNDAVRGA
Mb1708|M.bovis_AF2122/97 -RGHPPDPASVLGPDRLPGVRLWLYTNFHCNLCCDYCCVSSSPSTPHREL
Rv1681|M.tuberculosis_H37Rv -RGHPPDPASVLGPDRLPGVRLWLYTNFHCNLCCDYCCVSSSPSTPHREL
Mvan_5883|M.vanbaalenii_PYR-1 -RGRPPDPLLVLGPERMPGARLWMYTNFHCNLACDYCCVESSPQAPRREL
. . * . : :. :: . . :. . . *
MMAR_1021|M.marinum_M GSFAMAVRALENLAAAGFAD---AKISVVVTRHNVGQLDDFAALADRYGA
MUL_0773|M.ulcerans_Agy99 GSFAMAVRALENLAAAGFAD---AKISVVVTRHNVGQLDDFAALADRYGA
MAV_4478|M.avium_104 GSFDMAVRALQNLADAGFTQNGGAKISVVVTRHNVGQLDEFAALASRYGA
MSMEG_1423|M.smegmatis_MC2_155 GSFDMAVRALENLSNAGFTD---AKISVVVTRQNVDQLDEFAALAARYGA
TH_1901|M.thermoresistible__bu GSFDMAVRALQNLADAGFAD---AKISVVVTRHNVDQLDDFKALADRYGA
Mflv_5060|M.gilvum_PYR-GCK GSFAMAVRALENLKEAGFKD---AKISVVVTRHNIDQLDDFKALADTYGA
MAB_3835c|M.abscessus_ATCC_199 GSFDMAVRALENLAAAGFKD---AKISVVVTRHNVDQLDEFASLAARYGA
Mb1708|M.bovis_AF2122/97 G-AERIGRIVGEAARWGVRE-------LFLTGGEPFLLPDIDTIIATCVK
Rv1681|M.tuberculosis_H37Rv G-AERIGRIVGEAARWGVRE-------LFLTGGEPFLLPDIDTIIATCVK
Mvan_5883|M.vanbaalenii_PYR-1 G-ADRIARLAREAADWGVRE-------VFLTGGEPFLLSDIGTIVRSCAA
* * : *. : :.:* : * :: ::
MMAR_1021|M.marinum_M TLRITRLRPSGRGADVWEELHPTAAQQVALYDWLVAKGERVLTGDSFFHL
MUL_0773|M.ulcerans_Agy99 TLRITRLRPSGRGADVWEELHPTAAQQVALYDWLVAKGERVLTGDSFFHL
MAV_4478|M.avium_104 TLRITRLRPSGRGADVWDELHPTADQQVQLYDWLVAKGERVLTGDSFFHL
MSMEG_1423|M.smegmatis_MC2_155 TLRITRLRPSGRGADVWDDLHPTAEQQRQLYDWLVAKGDRVLTGDSFFHL
TH_1901|M.thermoresistible__bu TLRITRLRPSGRGADVWDELHPTAEQQVQLYNWLVAHGEKVLTGDSFFHL
Mflv_5060|M.gilvum_PYR-GCK TLRITRLRPSGRGADVWDDLHPTADQQVQLYNWLVAHGERVLTGDSFFHL
MAB_3835c|M.abscessus_ATCC_199 TLRITRLRPSGRGADVWDELHPTAAQQRQLYDWLVRNGERVLTGDSFFHL
Mb1708|M.bovis_AF2122/97 QLPTTVLTNG----MVFKGRGRRALESLPRG-LALQISLDSATPELHDAH
Rv1681|M.tuberculosis_H37Rv QLPTTVLTNG----MVFKGRGRRALESLPRG-LALQISLDSATPELHDAH
Mvan_5883|M.vanbaalenii_PYR-1 LLPTTVLTNG----MVFRGRGLRELDAIPRDNVALQISLDSATSELHDSH
* * * . *: : : . * : .
MMAR_1021|M.marinum_M APLGS-SGALAGLNMCG-AGRVVCLIDPVGDVYACPFAIHDRFLAGNVLT
MUL_0773|M.ulcerans_Agy99 APLGS-SGALAGLNMCG-AGRVVCLIDPVGDVYACPFAIHDRFLAGNVLT
MAV_4478|M.avium_104 APLGQ-SGALAGLNMCG-AGRVVCLIDPVGDVYACPFAIHDRFLAGNVLS
MSMEG_1423|M.smegmatis_MC2_155 SGLGA-PGALAGLNLCG-AGRVVCLIDPVGDVYACPFAIHDKFLAGNILS
TH_1901|M.thermoresistible__bu SGLGE-PGALAGLNLCG-AGRVVCLIDPVGDVYACPFAIHDRFLAGNVLT
Mflv_5060|M.gilvum_PYR-GCK SGLGE-PGALAGLNLCG-AGRVVCLIDPVGDVYACPFAIHDKFLAGNILT
MAB_3835c|M.abscessus_ATCC_199 SAYGDGSGGLPGLNMCG-AGRVVCLIDPVGDVYACPFAIHDRFLAGNVLS
Mb1708|M.bovis_AF2122/97 RGAGTWVKAVAGIRLALSLGFRVRVAATVASPAPGELTAFHDFLDGLGIA
Rv1681|M.tuberculosis_H37Rv RGAGTWVKAVAGIRLALSLGFRVRVAATVASPAPGELTAFHDFLDGLGIA
Mvan_5883|M.vanbaalenii_PYR-1 RGHGSWARAVEGIRVARGLGFRVRVAATVAAPVPGELKAFHDFLDELGIA
* .: *:.:. * * : .*. . : .. ** ::
MMAR_1021|M.marinum_M DGGFDQVWKNAPLFRQLREPQSAGACGSCGHYDSCRGGCMAAKFFTGLPL
MUL_0773|M.ulcerans_Agy99 DGGFDQVWKNAPLFRQLREPQSAGACGSCGHYDSCRGGCMAAKFFTGLPL
MAV_4478|M.avium_104 DGGFDNVWKNAPLFRELREPQSAGACGSCGHYDSCRGGCMAAKFFTGLPL
MSMEG_1423|M.smegmatis_MC2_155 DGGFQNVWQHSELFRELREPQSAGACASCGHFDACRGGCMAAKFFTGLPL
TH_1901|M.thermoresistible__bu DGGFDNVWKNSQLFRELREPQSAGACSGCSHFDSCRGGCMAAKFFTGLPL
Mflv_5060|M.gilvum_PYR-GCK SNGFEDVWQNSELFRELREPQSAGACSGCNHYDACRGGCMAAKFFTGLPM
MAB_3835c|M.abscessus_ATCC_199 DNGFDQVWKHSQLFSELREPQSAGACGSCGHYDSCRGGCMAAKFFTGLPM
Mb1708|M.bovis_AF2122/97 PG--------DQLVRPIALEGAASQGVALTRESLVPEVTVTADGVYWHPV
Rv1681|M.tuberculosis_H37Rv PG--------DQLVRPIALEGAASQGVALTRESLVPEVTVTADGVYWHPV
Mvan_5883|M.vanbaalenii_PYR-1 QD--------DQVVRPVAREGSAADGVQITRASLVPEVAVTAEGVYWHPV
. :. : :*. : . ::*. . *:
MMAR_1021|M.marinum_M DGPDPECVQGYGAPALAQERHAPRPRVDHSRGSR----VSAPVPLTLTTR
MUL_0773|M.ulcerans_Agy99 DGPDPECVQGYGAPALAQERHAPRPRVDHSRGSR----E-----------
MAV_4478|M.avium_104 DGPDPECVQGHSAAALAGDREAPRPRADHSRGKR----IRQPVPLTLSVR
MSMEG_1423|M.smegmatis_MC2_155 DGPDPECVEGWGAPALEKERVKPKPSGDHSRGT-----KQGPVALKLLTK
TH_1901|M.thermoresistible__bu DGPDPECVEGHGAPALARERTKPKPRVDHSRG--------GPVALKLLTK
Mflv_5060|M.gilvum_PYR-GCK DGPDPECVQGYGEPALAADRDKPKSSVDHSRSGG-RGKPKGPIPLTLLSA
MAB_3835c|M.abscessus_ATCC_199 DGPDPECVQGYGEAALAADRVVPKPSGDHSHSKSKRGPATGPVALTLTRR
Mb1708|M.bovis_AF2122/97 AATDERALVTRTVEPLTPALDMVSRLFAEQWTRA-----AEEAALFPCA-
Rv1681|M.tuberculosis_H37Rv AATDERALVTRTVEPLTPALDMVSRLFAEQWTRA-----AEEAALFPCA-
Mvan_5883|M.vanbaalenii_PYR-1 AAIDDDALVTRQIEPLAPALDEIAHAFAELWARK-----ANAAQLFPCA-
. * .: .* .
MMAR_1021|M.marinum_M --------PPARLCNESPV-------
MUL_0773|M.ulcerans_Agy99 --------------------------
MAV_4478|M.avium_104 PPVLTPAAPPARLCNESPV-------
MSMEG_1423|M.smegmatis_MC2_155 --------PPARFCNESPV-------
TH_1901|M.thermoresistible__bu --------PPARLCNESPV-------
Mflv_5060|M.gilvum_PYR-GCK --------PPKKFCNESPV-------
MAB_3835c|M.abscessus_ATCC_199 --------PPSRACDENPLSTLRAGR
Mb1708|M.bovis_AF2122/97 --------------------------
Rv1681|M.tuberculosis_H37Rv --------------------------
Mvan_5883|M.vanbaalenii_PYR-1 --------------------------