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VSRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVG VDKIRLTGGEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITISLDTLRP DRFKAISQRGTHYKVIEGIEAVAAAGFTDTKLDSVVIRGFNDDELSDLIEFARNVNAEVRFIEYMDVGGA TQWSMDKVFTKAQMLSTLGKKYGPIAALPKYDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADG IWLHCLYALSGINLRESVRAGASANDVVQILQRGWRDRANRGAEQRLAQRTRQVFLPVSRLKRDPHLEMH TRGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3355c | moaA3 | - | 100% (354) | molybdenum cofactor biosynthesis protein A |
| M. bovis AF2122 / 97 | Mb3136 | moaA1 | e-152 | 75.73% (342) | molybdenum cofactor biosynthesis protein A |
| M. bovis AF2122 / 97 | Mb0893c | moaA | 9e-46 | 34.48% (319) | molybdenum cofactor biosynthesis protein A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1705 | moaA | 5e-49 | 36.45% (310) | molybdenum cofactor biosynthesis protein A |
| M. tuberculosis H37Rv | Rv3109 | moaA1 | 1e-152 | 75.44% (342) | molybdenum cofactor biosynthesis protein A |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0871c | moaA | 3e-52 | 38.73% (315) | molybdenum cofactor biosynthesis protein A |
| M. marinum M | MMAR_4663 | moaA | 1e-45 | 34.82% (313) | molybdenum cofactor biosynthesis protein A2 MoaA2 |
| M. avium 104 | MAV_4478 | - | 2e-07 | 26.74% (187) | radical SAM domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5698 | moaA | 3e-45 | 33.55% (313) | molybdenum cofactor biosynthesis protein A |
| M. thermoresistible (build 8) | TH_1071 | moaA | 8e-53 | 37.14% (315) | molybdenum cofactor biosynthesis protein A |
| M. ulcerans Agy99 | MUL_0281 | moaA | 1e-45 | 34.27% (321) | molybdenum cofactor biosynthesis protein A |
| M. vanbaalenii PYR-1 | Mvan_5047 | moaA | 1e-47 | 36.54% (312) | molybdenum cofactor biosynthesis protein A |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3355c|M.bovis_AF2122/97 MSRSGL--CINESP----------------IRDRCGR---TMGDLRLSVI
Rv3109|M.tuberculosis_H37Rv MSTPTLPDMVAPSPR-------------VRVKDRCRR---MMGDLRLSVI
MMAR_4663|M.marinum_M MTVTALGVPTVRGRS-EGSAIASDAPGDGPLLDRFGR---SATDLRVSLT
MUL_0281|M.ulcerans_Agy99 MTVTALGVPTVRGRS-EGSAVASDAPGDGPLLDRFGR---SATDLRVSLT
MSMEG_5698|M.smegmatis_MC2_155 MTVTALGLPTVARSTGDGSAGASPAPADGPLVDTYGR---AATDLRVSLT
TH_1071|M.thermoresistible__bu MTVTALGLPAVRRPS-----PPSAPPASGPLVDTFGR---VHTDLRISLT
Mflv_1705|M.gilvum_PYR-GCK MTVVPLGLPSVQRPS-------TPAPATGPLIDTFGR---VATDLRVSLT
Mvan_5047|M.vanbaalenii_PYR-1 MTVVALGVPSVHRPQ-------SPAPEEGPLVDTFGR---VATDLRVSLT
MAB_0871c|M.abscessus_ATCC_199 ---------------------------MTPLIDSFGR---IATDLRVSLT
MAV_4478|M.avium_104 -MTTAAPVPR--------------------LIEQFEHGLDAPICLTWELT
: : : * .:
Mb3355c|M.bovis_AF2122/97 DQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIA-VGVDKIRLTG
Rv3109|M.tuberculosis_H37Rv DQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLS-VGVSKVRITG
MMAR_4663|M.marinum_M DRCNLRCGYCMPAEGLNWLPGEQLLGPAELARLLRIAVTRLGITSVRFTG
MUL_0281|M.ulcerans_Agy99 DRCNLRCGYCMPAEGLNWLPGEQLLGPAELARLPRIAVTPLGITSVRFTG
MSMEG_5698|M.smegmatis_MC2_155 DRCNLRCTYCMPAEGLNWLPGDALLSPTELARLLRIAVARLGITSVRFTG
TH_1071|M.thermoresistible__bu DRCNLRCTYCMPAEGLDWLPGEHLLRPDELARLLHIAVTRLGITNVRFTG
Mflv_1705|M.gilvum_PYR-GCK DLCNLRCTYCMPAEGLDWMPRDQKLTPDELTRLLRIGVTRLGITSIRFTG
Mvan_5047|M.vanbaalenii_PYR-1 DLCNLRCTYCMPAEGLDWLPSDEKLNPDELIRLLGVAVTRLGITSVRFTG
MAB_0871c|M.abscessus_ATCC_199 DRCNLRCTYCMPAEGLDWLRSETLLTTDEYIRLIGIAVTRLGIDSVRFTG
MAV_4478|M.avium_104 YACNLACVHCLSSSGK---RDPRELSTRQCMDIIDELER-MQVFYVNIGG
*** * :*:. * : : : : :.: *
Mb3355c|M.bovis_AF2122/97 GEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARK-LKSAG
Rv3109|M.tuberculosis_H37Rv GEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDG-LKAAG
MMAR_4663|M.marinum_M GEPLLARHLEEVVAAAAQLRPR----PEISLTTNGVGLAKRAAA-LAEAG
MUL_0281|M.ulcerans_Agy99 GEPLLARHLEEVVAAAAQLRPR----PEISLTTNGVGLAKRAAA-LAEAG
MSMEG_5698|M.smegmatis_MC2_155 GEPLVVRHLEEVVAAAAALEPR----PEITLTTNGLGLARRAEG-LKKAG
TH_1071|M.thermoresistible__bu GEPLVARHLEEVVAAAAAERPR----PEIALTTNGIGLAKRARR-LKDAG
Mflv_1705|M.gilvum_PYR-GCK GEPLVVPHLEDVLAATTALQPR----PEITLTTNGIGLAQRAAG-LRRAG
Mvan_5047|M.vanbaalenii_PYR-1 GEPLVVPHLEDVVAATAALRPR----PEITLTTNGVGLAKRAAG-LKRAG
MAB_0871c|M.abscessus_ATCC_199 GEPLIFKDLEKLVAAVAGMSPR----PDIAVTTNGVGLDRKAVA-LREAG
MAV_4478|M.avium_104 GEPTVRPDFWELVDYATAHHVG------VKFSTNGVRITPEVAARLAASD
*** : .: :: : : .:***: : .. * :.
Mb3355c|M.bovis_AF2122/97 MRRITISLDTLRPDRFKAISQRGTHYKVIEGIEAVAAAGFTD--TKLDSV
Rv3109|M.tuberculosis_H37Rv MKRITVSLDTLQPERFKAISQRNSHDKVIAGIKAVAAAGFTD--TKIDTT
MMAR_4663|M.marinum_M LDRVNVSLDTVDRAHFAAITRRDRLTDVLDGLAGARAAGLTP--VKVNAV
MUL_0281|M.ulcerans_Agy99 LDRVNVSLDTVDRAHFAAVTRRDRLTDVLDGLAGARAAGLTP--VKVNAV
MSMEG_5698|M.smegmatis_MC2_155 LNRINVSLDSVDAAHFARITRRDRLPDVLAGLAAAKAAGLEP--VKVNAV
TH_1071|M.thermoresistible__bu LDRVNVSLDTVDPVRFARITRRDRLADVLAGLEAARAAGLTP--VKVNAV
Mflv_1705|M.gilvum_PYR-GCK LNRINVSLDTVDPARFAAITRRDRFDDVIAGLHAAKEAGLQP--VKVNAV
Mvan_5047|M.vanbaalenii_PYR-1 LDRINVSLDTVDPARFAAITRRDRFTEVVAGLRAAKEAGLDP--VKVNAV
MAB_0871c|M.abscessus_ATCC_199 LDRINVSLDTLDAHRFAAITRRDRLSDVLLGLKAAGSAGLSP--IKINAV
MAV_4478|M.avium_104 YVDVQISLDGATAEVNDAVRGPGSFDMAVRALQNLADAGFTQNGGAKISV
: :*** : . .: .: **: :.
Mb3355c|M.bovis_AF2122/97 VIRGFNDDELSDLIEFARNVNAEVRFIEYMDVG-GATQWSMDK-------
Rv3109|M.tuberculosis_H37Rv VMRGANHDELADLIEFARTVNAEVRFIEYMDVG-GATHWAWEK-------
MMAR_4663|M.marinum_M LDPETGRQDVVELLRFCLEQGYQLRVIEQMPLD-AGHQWRRNA-------
MUL_0281|M.ulcerans_Agy99 LDPETGRQDVVELLRFCLEQGYQLRVIEQMPLD-AGHQWRRNA-------
MSMEG_5698|M.smegmatis_MC2_155 LDPVSGLDDAVELLRYCLQHGYQLRIIEQMPLD-ASHSWQRDN-------
TH_1071|M.thermoresistible__bu LDAETGLDDAVQLLRFCLDRGYQLRIIEQMPLD-AGHQWRRDQ-------
Mflv_1705|M.gilvum_PYR-GCK LDPVTGLQDAVALLGFCLENGYQLRIIEQMPLD-AGHSWQRDR-------
Mvan_5047|M.vanbaalenii_PYR-1 LDPVSGLDDVVSLLRFCLEHGYQLRVIEQMPLD-AGHSWERER-------
MAB_0871c|M.abscessus_ATCC_199 LTPEQYKEDAVALLHFSLEHGYELRIIEQMPLD-AGHSWSRAR-------
MAV_4478|M.avium_104 VVTRHNVGQLDEFAALASRYGATLRITRLRPSGRGADVWDELHPTADQQV
: : : . . :*. . . .. *
Mb3355c|M.bovis_AF2122/97 -----VFTKAQMLSTLGKKYGPIAA--------------------LPKYD
Rv3109|M.tuberculosis_H37Rv -----VFTKANMLESLEKRYGRIEP--------------------LPKHD
MMAR_4663|M.marinum_M -----LLGSDDVLAALQPHFRLRPD--------------------PAPRG
MUL_0281|M.ulcerans_Agy99 -----LLGSDDVLAALQPHFRLRPD--------------------PAPRG
MSMEG_5698|M.smegmatis_MC2_155 -----VIDADRILQTLQQHFELTPD--------------------SRPRG
TH_1071|M.thermoresistible__bu -----TLSADEVLAALQREFRLSPD--------------------PTPRG
Mflv_1705|M.gilvum_PYR-GCK -----ALSADDILDTLRRHFTLTPD--------------------PAPRG
Mvan_5047|M.vanbaalenii_PYR-1 -----ALSADVILSALRRHFTLTPD--------------------PRPRG
MAB_0871c|M.abscessus_ATCC_199 -----MVTADEIHAALSREFSLSED--------------------PAPRG
MAV_4478|M.avium_104 QLYDWLVAKGERVLTGDSFFHLAPLGQSGALAGLNMCGAGRVVCLIDPVG
. : : .
Mb3355c|M.bovis_AF2122/97 SAPANRYRLPDG--------------------TTFGIIASTTEPFCATCD
Rv3109|M.tuberculosis_H37Rv TAPANRYALPDG--------------------TTFGIIASTTEPFCATCD
MMAR_4663|M.marinum_M SAPAELWLVDAGPDT---------------PAGKFGVIASVSHAFCSTCD
MUL_0281|M.ulcerans_Agy99 SAPAELWLVDAGPDT---------------PAGKFGVIASVSHAFCSTCD
MSMEG_5698|M.smegmatis_MC2_155 SAPAELWQVAEGPTH---------------AAGTVGVIASVSHAFCSACD
TH_1071|M.thermoresistible__bu SAPAQLWRIDG-------------------TGATVGIIATVSHAFCSACD
Mflv_1705|M.gilvum_PYR-GCK SAPAQLWRVHDG-TG---------------VVGRVGIIASVSHAFCSTCD
Mvan_5047|M.vanbaalenii_PYR-1 SAPAQLWQVHDD-GH---------------VTGHIGIIASVSDAFCSTCD
MAB_0871c|M.abscessus_ATCC_199 SAPAQRWLVNGG-------------------PATVGIIASVSRPFCGDCD
MAV_4478|M.avium_104 DVYACPFAIHDRFLAGNVLSDGGFDNVWKNAPLFRELREPQSAGACGSCG
. * : : : . : *. *.
Mb3355c|M.bovis_AF2122/97 RSRLTADGIWLHCLYA---LSGINLRESVRAGASANDVVQILQRGWRDRA
Rv3109|M.tuberculosis_H37Rv RSRLTADGLWLHCLYA---ISGINLREPLRAGATHDDLVETVTTGWRRRT
MMAR_4663|M.marinum_M RTRLTADGQVRSCLFS---TEETDLRGLLRAGAGDEAIEAAWRSAMWAKP
MUL_0281|M.ulcerans_Agy99 RTRLTADGQVRSCLFS---TEETDLRGLLRAGAGDEAIEAAWRGAMWAKP
MSMEG_5698|M.smegmatis_MC2_155 RTRLTADGQIRSCLFS---REETDLRHLLRGGADDAEIEAAWRAAMWSKP
TH_1071|M.thermoresistible__bu RTRLTADGQVRNCLFA---QQETDLRGLLRSGADDDAVEAAWRAAMWAKA
Mflv_1705|M.gilvum_PYR-GCK RSRLTADGQVRNCLFA---RDETDLRALLRSGADDDVLEAAWRAAMWAKA
Mvan_5047|M.vanbaalenii_PYR-1 RSRLTADGQVRNCLFA---RDETDLRALLRSGADDAALEDAWRAAMWAKA
MAB_0871c|M.abscessus_ATCC_199 RTRLTADGQVRNCLFA---TTETDLRGLLRSGASDAEVASAWQAAMWGKK
MAV_4478|M.avium_104 HYDSCRGGCMAAKFFTGLPLDGPDPECVQGHSAAALAGDREAPRPRADHS
: .* ::: : . .* :
Mb3355c|M.bovis_AF2122/97 NRGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG
Rv3109|M.tuberculosis_H37Rv DRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG
MMAR_4663|M.marinum_M AGHGINNPDFVQ-------------PQRPMSAIGG
MUL_0281|M.ulcerans_Agy99 AGHGINNPDFLQ-------------PQRPMSAIGG
MSMEG_5698|M.smegmatis_MC2_155 AGHGINDPDFVQ-------------PVRPMSAIGG
TH_1071|M.thermoresistible__bu AGHGINDPDFVQ-------------PARPMSAIGG
Mflv_1705|M.gilvum_PYR-GCK AGHGINDPDFVQ-------------PDRPMSAIGG
Mvan_5047|M.vanbaalenii_PYR-1 AGHGINDPGFVQ-------------PDRPMSAIGG
MAB_0871c|M.abscessus_ATCC_199 PGHGINDPSFLQ-------------PDRPMSAIGG
MAV_4478|M.avium_104 RGKRIRQPVPLTLSVRPPVLTPAAPPARLCNESPV
. *