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VRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLHVGALAVLSQPDNGTGRYLRK VFSAAVARQQVAPWWRRRPHRSLTSLGQWSWRTETEVDLDYHVRLSALPPRAGTAELWALVSELHAGMLD RSRPLWQVDLIEGLPGGRCAVYVKVHHALADGVSVMRLLQRIVTADPHQRQMPTLWEVPAQASVAKHTAP RGSSRPLTLAKGVLGQARGVPGMVRVVADTTWRAAQCRSGPLTLAAPHTPLNEPIAGARSVAGCSFPIER LRQVAEHADATINDVVLAMCGGALRAYLISRGALPGAPLIAMVPVSLRDTAVIDVFGQGPGNKIGTLMCS LATHLASPVERLSAIRASMRDGKAAIAGRSRNQALAMSALGAAPLALAMALGRVPAPLRPPNVTISNVPG PQGALYWNGARLDALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLAHELELLVGVS EAGPGTRLRRIAGRR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0919 | - | - | 100% (505) | hypothetical protein Mb0919 |
M. bovis AF2122 / 97 | Mb3766c | - | 1e-92 | 44.14% (469) | hypothetical protein Mb3766c |
M. bovis AF2122 / 97 | Mb3761c | - | 3e-91 | 40.94% (469) | hypothetical protein Mb3761c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1058 | - | 2e-72 | 36.00% (475) | hypothetical protein Mflv_1058 |
M. tuberculosis H37Rv | Rv0895 | - | 0.0 | 100.00% (505) | hypothetical protein Rv0895 |
M. leprae Br4923 | MLBr_01244 | - | 1e-23 | 28.65% (363) | hypothetical protein MLBr_01244 |
M. abscessus ATCC 19977 | MAB_4544c | - | 1e-85 | 38.25% (468) | hypothetical protein MAB_4544c |
M. marinum M | MMAR_5271 | - | 5e-92 | 40.78% (461) | hypothetical protein MMAR_5271 |
M. avium 104 | MAV_0355 | - | 2e-90 | 43.46% (451) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
M. smegmatis MC2 155 | MSMEG_6322 | - | 2e-93 | 43.17% (454) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
M. thermoresistible (build 8) | TH_2030 | - | 8e-84 | 40.35% (461) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_2057 | - | 1e-88 | 41.43% (461) | hypothetical protein MUL_2057 |
M. vanbaalenii PYR-1 | Mvan_0444 | - | 4e-72 | 35.67% (471) | hypothetical protein Mvan_0444 |
CLUSTAL 2.0.9 multiple sequence alignment Mb0919|M.bovis_AF2122/97 MRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLH Rv0895|M.tuberculosis_H37Rv MRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLH MMAR_5271|M.marinum_M ---------------------------MEL-MMPTDSMFLFVESREHPMH MAV_0355|M.avium_104 ---------------------------MEL-IMPTDAVFLLGESREHPMH MUL_2057|M.ulcerans_Agy99 ---------------------------MKL-IAPTDSMFLLGESREHPMH MSMEG_6322|M.smegmatis_MC2_155 ------------------------MNRMQL-MSPTDSMFLIAESREHPMH TH_2030|M.thermoresistible__bu ---------------------------MRL-ISPADSMFLLAESREHPMH MAB_4544c|M.abscessus_ATCC_199 ---------------------------MPF-MPVSDSMFLIGETREHPFH Mflv_1058|M.gilvum_PYR-GCK ------------------------MSANSVRLGLQDLMFIYGETSSSKMH Mvan_0444|M.vanbaalenii_PYR-1 ---------------------------MDL-LEPLDAAMITAEALSEPLH MLBr_01244|M.leprae_Br4923 --------------------MADSVEGIGPFDELGALDYLLHRGEANPRT : . Mb0919|M.bovis_AF2122/97 VGALAVLSQP-DNGTGRYLRKVFSAAVAR-QQVAPWWRRRPHRSLTSLGQ Rv0895|M.tuberculosis_H37Rv VGALAVLSQP-DNGTGRYLRKVFSAAVAR-QQVAPWWRRRPHRSLTSLGQ MMAR_5271|M.marinum_M VGGLSLFEPP-EGAGPDFVRNFYEALVAN-HEFQPTFRKHPATIGGGIAR MAV_0355|M.avium_104 VGGLQLYQPP-EGAGRNFVRDFYKQLVAQ-PDFQPTFRKHPAKFVGGIAN MUL_2057|M.ulcerans_Agy99 VGGLQLFQPP-EDADENFVTEAYEAMLGC-TDVQPMFRKHPAFLG-AMTN MSMEG_6322|M.smegmatis_MC2_155 VGGLALYDPP-DDAGPEFVRELYEEMVRH-TDFQPVFRKHPATLLGGIAN TH_2030|M.thermoresistible__bu VAGLQLFEPPPGTAGPEFLQGLHQRLAAG-RELHPTFRKHPATLFGGIAH MAB_4544c|M.abscessus_ATCC_199 VGGLQLFKPP-VDAGPDYAEVFYEQLMST-TEVSSDFRKRPGQPLAVMGN Mflv_1058|M.gilvum_PYR-GCK VGGLLPFTPP-ADAPRDYLRGMIDEARRQ-EVVAPWNRRLAYPRLQFSPL Mvan_0444|M.vanbaalenii_PYR-1 TAAVLILCPP-ADAGPGYVDELYRSALADTAELDPRFRRHPHAGLDTAGL MLBr_01244|M.leprae_Br4923 RAGIMAVELLDTTPDWNRFRSRIEDVSQR----VLRLRQKVVVPTLPTAA ..: *: Mb0919|M.bovis_AF2122/97 WSWRTETEVDLDYHVRLSALPPRAGTAELWALVSELHAGMLDRSRPLWQV Rv0895|M.tuberculosis_H37Rv WSWRTETEVDLDYHVRLSALPPRAGTAELWALVSELHAGMLDRSRPLWQV MMAR_5271|M.marinum_M VAWAYDDDLDVDYHVRRSALPSPGRVRDLLELTSRLHTSLLDRHRPLWEL MAV_0355|M.avium_104 LGWSYDADVDVDYHVRRSALPSPRRVRELLELTSRWHSSLLDRHRPLWET MUL_2057|M.ulcerans_Agy99 FAWTFDDDVELDYHFRRSALPRPGRVRELLELTSRLHGSLLDRHRPLWEA MSMEG_6322|M.smegmatis_MC2_155 VGWTLDDEVDLDYHLRRSALPSPGRPRELLELTSRVHGTLLDRHRPLWEA TH_2030|M.thermoresistible__bu LGWAVDDDVDFDYHLRRSALPGPGRIRELLDLTSRWHGTLLDRHRPLWEV MAB_4544c|M.abscessus_ATCC_199 LTWIVDDEVDWEYHVRRSALPRPARVRELLTVTSRWHSSPLDRHRPLWEM Mflv_1058|M.gilvum_PYR-GCK HSWVTDEDFDFDYHVRRSALASPGDERELGVLVSRLHSNHLDLTRPPWEL Mvan_0444|M.vanbaalenii_PYR-1 WVWHTDEIIDMRKHLQRRTLPAGADHEALWRLISELHSEPLERSRPMWMA MLBr_01244|M.leprae_Br4923 PRWVVDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTA * : .: *.: :. : : . : :: ** * Mb0919|M.bovis_AF2122/97 DLIEGLPGGRCAVYVKVHHALADGVSVMRLLQRIVTA--DPHQRQMPTLW Rv0895|M.tuberculosis_H37Rv DLIEGLPGGRCAVYVKVHHALADGVSVMRLLQRIVTA--DPHQRQMPTLW MMAR_5271|M.marinum_M HVVEGLSDGRFAMYAKMHHALIDGVSAAKLMQRTMSA--DPSDTEVRAMW MAV_0355|M.avium_104 HIVEGLKDGRFAIYTKVHHALIDGVSAQKLMQRALSS--DPDDPEIRAPW MUL_2057|M.ulcerans_Agy99 HLVEGLNDGRYAVYIKFHHSLQDGVSAQKLMQRAFST--DPDDDEIRVPW MSMEG_6322|M.smegmatis_MC2_155 YLIEGMADGRFAVYTKVHHSLIDGVSAMKLVERTLSE--DPSDTTVRVPW TH_2030|M.thermoresistible__bu HLVEGLADGRVAIYFKVHHALIDGVAVMKLMQRTLST--DPGDD-ARVPW MAB_4544c|M.abscessus_ATCC_199 HVVEGLSDGRLAVYTKMHHAVIDGVGALRMMMRSLSD--DPDARDCQAVW Mflv_1058|M.gilvum_PYR-GCK HVIEGLEGGRFALYMKIHHALVDGYSAMRMLGRSLST--DPASRDTRMFF Mvan_0444|M.vanbaalenii_PYR-1 YLIDGLADGRFVYYIKVHHTVIDGVAGLAMIAGALTT--DPDKRSMRPLY MLBr_01244|M.leprae_Br4923 TLVEGLAAGRAAMLLQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQP :::*: ** . :. *:: ** . :. ** Mb0919|M.bovis_AF2122/97 EVPAQASVAKHTAPRGSSR---PLTLAKGVLGQARGVPGMVRVVADTTWR Rv0895|M.tuberculosis_H37Rv EVPAQASVAKHTAPRGSSR---PLTLAKGVLGQARGVPGMVRVVADTTWR MMAR_5271|M.marinum_M NLPRPPRPESNGGGSS---------LVGSLVKMAGSVAGLAPSTLKLARA MAV_0355|M.avium_104 TLPKRSR---KAGPSS---------RLSSLVHAAGSVAALAPSTVSLARA MUL_2057|M.ulcerans_Agy99 ELKPRRRS-NPGHRSS---------PLRLLTETVGATASLAPSALSLARA MSMEG_6322|M.smegmatis_MC2_155 NLP-RRESSRRAGSSS---------LARTATGAATSLAALAPSTIRLARA TH_2030|M.thermoresistible__bu NLP-PPRRNP-AGPVS---------RLRSATGAVGSVAALAPSTLSLARA MAB_4544c|M.abscessus_ATCC_199 APAKRRAKSSIVSTTNTS----AIDLVKGAAGAVRQVVSIPPGLLKYGRH Mflv_1058|M.gilvum_PYR-GCK NVPSPTRSRRDPGAAESSNP--LTATLRALGGVSSAVTGGVSSAVDLTNA Mvan_0444|M.vanbaalenii_PYR-1 AHKSPAGNGSTSRRRIPNPLSLARVALRGLTGGIETARQLAIAEISTVAN MLBr_01244|M.leprae_Br4923 IPQDLSRNDLMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSG Mb0919|M.bovis_AF2122/97 AAQCRS--------GPLTLAAPHTPLNEPIAGARSVAGCSFPIERLRQVA Rv0895|M.tuberculosis_H37Rv AAQCRS--------GPLTLAAPHTPLNEPIAGARSVAGCSFPIERLRQVA MMAR_5271|M.marinum_M ALFEQQ--------LTLPFAAPHTMFNVKVGGARRCAAQSWSLERIRAVK MAV_0355|M.avium_104 ALVEQQ--------LTLPFGAPRTMLNVKIGGARRCAAQSWPLERIKNVK MUL_2057|M.ulcerans_Agy99 ALLEQQ--------LTLPFRAPKTMFNVRIGGARRVAAQSWSLDRIKAVK MSMEG_6322|M.smegmatis_MC2_155 ALLEQQ--------LTLPFGAPRTMFNVKIGGARRVAAQSWPLERLRRIK TH_2030|M.thermoresistible__bu ALLEQR--------LTLPFGAPRTMFNVRIGGARRVAAQSWPLQRIRRIR MAB_4544c|M.abscessus_ATCC_199 ALSDPQ--------LVKPLSAPHTMLNVSIGGARRFAAQTWSMARIKEAG Mflv_1058|M.gilvum_PYR-GCK LVNTQIRRDGENAHIAGSVSAPHSILNARISRNRRFATQQYEFDRLKKLS Mvan_0444|M.vanbaalenii_PYR-1 SLGSGT--------AALPLEAPYTRFNGRIGRERSFAGGSWPKSRIRAVQ MLBr_01244|M.leprae_Br4923 VVGYVRSG-----IRVLSQAAEPSPLLRQRSLATRTEAIEIQLSDLHKAA . * : : . :: Mb0919|M.bovis_AF2122/97 EHADATINDVVLAMCGGALRAYLISRGALPGAPLIAMVPVSLRDTAVIDV Rv0895|M.tuberculosis_H37Rv EHADATINDVVLAMCGGALRAYLISRGALPGAPLIAMVPVSLRDTAVIDV MMAR_5271|M.marinum_M QAAGVTVNDAVLAMCAGALRYYLIEQDALPDAPLIAMVPVSLRSKEQA-- MAV_0355|M.avium_104 NAAGVTVNDVVLAMCSGALRYYLLEQNALPDTPLIAMVPVSLRTEEEA-- MUL_2057|M.ulcerans_Agy99 NAADVTVNDVVLAMSAGALRAYLIDQHALPDAPLIAMVPVSLRKEGDA-- MSMEG_6322|M.smegmatis_MC2_155 AVTGATINDIVLAMCAGALRAYLAEQDALPDRPLIAMVPVSMRSEHEA-- TH_2030|M.thermoresistible__bu QAAGXTLNDVALAMCAGALRQYLLEHDALPATPLVAMVPVSLRSADES-- MAB_4544c|M.abscessus_ATCC_199 KALGGTVNDVVLAMCGGALRTYLEEQNALPDKPLVAMCPVSIRAEGDQ-- Mflv_1058|M.gilvum_PYR-GCK SQHGATLNDVALAIIGGGLRKFLSDFDKLPDRSLIAFLPVNVRPKGDE-- Mvan_0444|M.vanbaalenii_PYR-1 KATGVTGNDVLTTVVAGVLREWLLARDELPNSSLVAICPVTVRGREHSAE MLBr_01244|M.leprae_Br4923 KAGDGSINDAYLAGLVGALRRYHEALG-VSISTLPMAVPVNVRTEADV-- . : ** : * ** : :. .* **.:* Mb0919|M.bovis_AF2122/97 FGQGPGNKIGTLMCSLATHLASPVERLSAIRASMRDGKAAIAGRSRNQAL Rv0895|M.tuberculosis_H37Rv FGQGPGNKIGTLMCSLATHLASPVERLSAIRASMRDGKAAIAGRSRNQAL MMAR_5271|M.marinum_M --DSGGNMVGSVLCNLGTNVEDPAQRIEIISASMRANKKVLADLPRLQVL MAV_0355|M.avium_104 --DAGGNLVGAILCNLATDSDDPAQRLLTISESMRSNKKVFSQLPRFQAL MUL_2057|M.ulcerans_Agy99 --DRGGNMVGTLLCNLATNLDDPMKRLQVISQSMSDNKKVFAQLPRIQQL MSMEG_6322|M.smegmatis_MC2_155 --DAGGNMVGSILCSLGTDVEDPADRLAVIRRSITDNKRVFSELPRLQAL TH_2030|M.thermoresistible__bu --AGGGNRTGLVLCNLATDSDDPAERLDRISSSMRSNKRVFSQLPRVQAM MAB_4544c|M.abscessus_ATCC_199 --NAG-NSITALLANLATDKPDPLERFSAIRDSVQAAKSVLSEMTPLQRM Mflv_1058|M.gilvum_PYR-GCK ---GGGNAVGAILAPMGTDIEDPVERLDTITTATRAAKGQLQSMSPAAII Mvan_0444|M.vanbaalenii_PYR-1 -DDEHGNLFGLQLCPLGTDLADPLERLDYIHRAMTWAKHQVTDRGSNATM MLBr_01244|M.leprae_Br4923 ---VGSNRFVGVTLAAPLGTNDPAARMQKIRSQMTQRR----DEPAMNII * .* *: * : : Mb0919|M.bovis_AF2122/97 AMSALGAAPL--ALA-MALGRVPAPLRPPNVTISNVPGPQGALYWNGARL Rv0895|M.tuberculosis_H37Rv AMSALGAAPL--ALA-MALGRVPAPLRPPNVTISNVPGPQGALYWNGARL MMAR_5271|M.marinum_M ALSGLNMAPL--TLA-GVPGFLSTVPPPFNIVISNVPGGAQPLYYGGARL MAV_0355|M.avium_104 ALSAANLSSL--ALA-AVPGWVSATSPPFNIVISNVPGPTAPLYYGGARL MUL_2057|M.ulcerans_Agy99 ALSGLLTGGL--VFG-LVPGFVATAPPPFNVVISNVPGAPNPLYWRGARL MSMEG_6322|M.smegmatis_MC2_155 ALSALLIAPL--GLTTAFPGFVDATAPPFNLVISNVPGPKKPLYWRGARL TH_2030|M.thermoresistible__bu ALSAAMIAPL--GLG-AVPGVVSSAPPPFNLVISNVPGAPEPRYWMGARL MAB_4544c|M.abscessus_ATCC_199 LVGALNGAPV--LTG-AVPGLVDRTAPAFNVIISNVPGPRTDMFWNGFEM Mflv_1058|M.gilvum_PYR-GCK AYSAALLAPAGSQIAGALTGVQPPWPYTFNLCVSNVPGPREPLYFNGSRL Mvan_0444|M.vanbaalenii_PYR-1 LLLAPSIAVT---VLSPIAPLAPRLRRGYNVSISSVPGPQAEMYWNGAHL MLBr_01244|M.leprae_Br4923 GSLAPLMTVLP----ASVLDFIVDSVASSDVNASNIPAYPGDTYFAGAKI . :: *.:*. :: * .: Mb0919|M.bovis_AF2122/97 DALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLAHE Rv0895|M.tuberculosis_H37Rv DALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLAHE MMAR_5271|M.marinum_M DGSYPLSNIPDGQALNITLVNNADRLDFGLVGCRRSVPSLQRLLGHLETS MAV_0355|M.avium_104 DGNYPLSIVLDGQALNITLASNAGNLDFGLVGCRRSVPHLQRLLMHLESS MUL_2057|M.ulcerans_Agy99 VGNYPLSIALDGQAMNITVTNNADNLDFGLVGCRRSVPRLQRMLGHLETS MSMEG_6322|M.smegmatis_MC2_155 AGNYPLSIALDGQALNMTVVSNAHNLDFGLVGCRRSVPHLQRLLGHLETS TH_2030|M.thermoresistible__bu AGNYPLSIVLDGQALNITLVTNADNLDFGLVGARGSVPHLQRLLGHLEDS MAB_4544c|M.abscessus_ATCC_199 DGCYPASIPIDGVALNITCTSSGSSMHFGLTGCRTSVPHLQRILAHLEDA Mflv_1058|M.gilvum_PYR-GCK EATYPVSIPIHGMALNITLQSYADTMNLGFVGCRDRLPHLQRLAVYTGDA Mvan_0444|M.vanbaalenii_PYR-1 EEIYPVSTAIDGQALNVTMCSYADRVTFGYVSGRDVVPDIGSLIPLTERV MLBr_01244|M.leprae_Br4923 LRQYGIGPR-PGVAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEG * . * *: . . * : : Mb0919|M.bovis_AF2122/97 LELLVGVSEAGPGTRLRRIAGRR------------ Rv0895|M.tuberculosis_H37Rv LELLVGVSEAGPGTRLRRIAGRR------------ MMAR_5271|M.marinum_M LKDLEQAVGV------------------------- MAV_0355|M.avium_104 LKDLERAVGE------------------------- MUL_2057|M.ulcerans_Agy99 LKELERAVGV------------------------- MSMEG_6322|M.smegmatis_MC2_155 LKDLETATGA------------------------- TH_2030|M.thermoresistible__bu LQQLERAVGG------------------------- MAB_4544c|M.abscessus_ATCC_199 LTQLEESVA-------------------------- Mflv_1058|M.gilvum_PYR-GCK LAELEAASQI------------------------- Mvan_0444|M.vanbaalenii_PYR-1 LADLEAAVAAQS----------------------- MLBr_01244|M.leprae_Br4923 FDEVLALAGDPTPHAVPASFAARSSGSPAGWLSSS : :