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VKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLSI ARVAGHDDLPWPDPADWLAAVRASPLLADPPVLHLYDDRLLYLDRYWREEEQVCADLLALLTSRRPAGVP DLRRLFPTGFDEQRRAAEIALSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEPRPRIALAAPTGKA AARLAEAVRREMAKLDATDRARLGDLHAVTLHRLLGAKPGARFRQDRQNRLPHNVIVVDETSMVSLTLMA RLAEAVRPGARLILVGDADQLASVEAGAVLADLVDGFSVRDDALVAQLRTSHRFGKVIGTLAEAIRAGDG DAVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVL HWNRRVQAWLAEETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTGLRAVISGASGPLDVATG RLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVARAKRKVRVVGSEASVRAAIARRAV RASGLRMRLQSTGCG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0645c | recD | - | 100% (575) | exonuclease V alpha chain |
M. bovis AF2122 / 97 | Mb1283c | - | 5e-08 | 24.53% (428) | hypothetical protein Mb1283c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5131 | - | 0.0 | 66.12% (552) | exodeoxyribonuclease V, alpha subunit |
M. tuberculosis H37Rv | Rv0629c | recD | 0.0 | 99.83% (575) | exonuclease V alpha chain |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0398c | - | 0.0 | 67.62% (559) | exodeoxyribonuclease V, alpha subunit (RecD) |
M. marinum M | MMAR_0956 | recD | 0.0 | 66.84% (573) | exodeoxyribonuclease V (alpha chain), RecD |
M. avium 104 | MAV_4544 | recD | 0.0 | 71.40% (563) | exodeoxyribonuclease V, alpha subunit |
M. smegmatis MC2 155 | MSMEG_1325 | recD | 0.0 | 70.04% (554) | exodeoxyribonuclease V, alpha subunit |
M. thermoresistible (build 8) | TH_1441 | - | 8e-05 | 37.86% (103) | PROBABLE ATP-DEPENDENT DNA HELICASE |
M. ulcerans Agy99 | MUL_0707 | recD | 0.0 | 66.84% (573) | exodeoxyribonuclease V (alpha chain), RecD |
M. vanbaalenii PYR-1 | Mvan_1208 | - | 0.0 | 66.31% (558) | exodeoxyribonuclease V, alpha subunit |
CLUSTAL 2.0.9 multiple sequence alignment Mb0645c|M.bovis_AF2122/97 -----------------------------MKLTDVDFAVEASGMVRAFNQ Rv0629c|M.tuberculosis_H37Rv -----------------------------MKLTDVDFAVEASGMVRAFNQ MAV_4544|M.avium_104 ------------------------------MLPER---VFDAGPLRPFAD Mflv_5131|M.gilvum_PYR-GCK ------------------------------------------MSLDAF-- Mvan_1208|M.vanbaalenii_PYR-1 ------------------------------------------MTVEAF-- MAB_0398c|M.abscessus_ATCC_199 -----------------------------------------MSLVEAF-- MSMEG_1325|M.smegmatis_MC2_155 -----------------------------------------MSLLEAF-- MMAR_0956|M.marinum_M ------------------------MTIDVVDPADWRQAASASGPLRTFNE MUL_0707|M.ulcerans_Agy99 ------------------------MTIEVVDPADWRQAASASGPLRTFNE TH_1441|M.thermoresistible__bu LSGAGRAGRIGAAVTARHSPADLAEALGLFPPTEEQAAVIAAPPGPLVVI . Mb0645c|M.bovis_AF2122/97 AGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLS-I Rv0629c|M.tuberculosis_H37Rv AGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLS-I MAV_4544|M.avium_104 AGIFEAADIHVAQRLTALTGESDDRVALAVALLVRALRGGSVCVDLRA-V Mflv_5131|M.gilvum_PYR-GCK AEVFEPADIHVAQRLTELGRDSDPTVALAVALAVRAVRSGSVCVDLRT-V Mvan_1208|M.vanbaalenii_PYR-1 SELFEPADLHVAQRLTTLGKEGDDSVALAVALAVRALRGGSVCVDLRA-I MAB_0398c|M.abscessus_ATCC_199 GEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRA-V MSMEG_1325|M.smegmatis_MC2_155 AEILEPADVHVAQRLTVLADEPDASVELAVALAVRALRGGSVCVDLRS-V MMAR_0956|M.marinum_M AGVIDAADVHVAQRLAAMSGESDPVVLLAIAFVVRALRGGSVCVDLST-I MUL_0707|M.ulcerans_Agy99 ARVIDAADVHVAQRLAAMSGESDPVVLLAIAFVVRALRGGSVCVDLST-I TH_1441|M.thermoresistible__bu AGAGAGKTETMAARVVWLVANGYARPDQVLGLTFTRKAAGQLLRRVRSRL . :* *: : : .:.. . .*.: : : : Mb0645c|M.bovis_AF2122/97 ARVAGHDDLPWPDPADWLAA---------VRASPLLADPPVLHLYDDR-L Rv0629c|M.tuberculosis_H37Rv ARVAGHDDLPWPDPADWLAA---------VRASPLLADPPVLHLYDDR-L MAV_4544|M.avium_104 PAQVGAADLPWPAAGDWLAA---------VRASPLLGPPPVLRFFGD--L Mflv_5131|M.gilvum_PYR-GCK AAQVGVPELPWPDPDGWLST---------VGASPLAEHK-VVRLDGD--L Mvan_1208|M.vanbaalenii_PYR-1 ATQVGMPELPWPEPDRWLAA---------VGASPLADER-VLRMHGD--L MAB_0398c|M.abscessus_ATCC_199 AAQVDMPSLPWPAADDWLAA---------VRASPLAGEPPVLRLFGD--L MSMEG_1325|M.smegmatis_MC2_155 AGQVELPDLPWPDPDAWLAA---------LAASPLLGQPPVLRLFGD--L MMAR_0956|M.marinum_M EAQVGIADLPWPAAGEWLAA---------VRASPLVGSPAVLRLHEDN-L MUL_0707|M.ulcerans_Agy99 EAQVGIADLPWPAAGEWLAA---------VRASPLVGSPAVLRLHEDN-L TH_1441|M.thermoresistible__bu ARLAGTGLVPANSAPDWTTESVTVSTYHAFAGTLLREHGLLLPVEPDTRL . :* . * : . .: * :: . * * Mb0645c|M.bovis_AF2122/97 LYLDRYWREEEQVCADLLALLT--SRRPAGVPDLRRLFPTGFD-----EQ Rv0629c|M.tuberculosis_H37Rv LYLDRYWREEEQVCADLLALLT--SRRPAGVPDLRRLFPTGFD-----EQ MAV_4544|M.avium_104 LYFDRYWLEEEQVCTDLLALSA--PAGDVESSCYERLFPPGYE-----EQ Mflv_5131|M.gilvum_PYR-GCK LYLDRYWREEEQVRDDVVALLS--SPPRTAVPGLERLFPAGWE-----EQ Mvan_1208|M.vanbaalenii_PYR-1 LYLDRYWREEQQVCDDVLALLA--SPLPATAPSIERLFPAGWE-----EQ MAB_0398c|M.abscessus_ATCC_199 LYLDRYWREEQQVCTDVQALMAA-AQPRTEVPTYERLFPQGFE-----EQ MSMEG_1325|M.smegmatis_MC2_155 LYLDRYWLEEQQVCDDVLALVS--ARPGGAVPDVSRLFGAGFE-----EQ MMAR_0956|M.marinum_M VYLDRYWREEQQVADDILALLAARASASGPAIEVNRLFPPGYE-----EQ MUL_0707|M.ulcerans_Agy99 VYLDRYWREEQQVADDILALLAARASASGPAIEVNRLFPPGYE-----EQ TH_1441|M.thermoresistible__bu IGETELWQLAYRVVCEHPGPLDTDKTPAAITAMVLRLAGQLAEHLVDTDQ : . * :* : . ** : :* Mb0645c|M.bovis_AF2122/97 RRAAEIALSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEP------ Rv0629c|M.tuberculosis_H37Rv RRAAEIALSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEP------ MAV_4544|M.avium_104 RAAARIAVSQALTVLTGGPGTGKTTTVARLLALLVEQAERAGEP------ Mflv_5131|M.gilvum_PYR-GCK RAAAEAALTRSLTVLTGGPGTGKTTTVARLLAAFAEQAELAGGP------ Mvan_1208|M.vanbaalenii_PYR-1 REAAKVALRQSLTVLTGGPGTGKTTTVARLLASIAEQAESAGGA------ MAB_0398c|M.abscessus_ATCC_199 RAAADIALSQGLTVLTGGPGTGKTTTVARLLALLADQASSASAA------ MSMEG_1325|M.smegmatis_MC2_155 RAAAKVALSQGLTVLTGGPGTGKTTTVARLLALLAEQAALAGKP------ MMAR_0956|M.marinum_M RAAAKIALAQGLTVLTGGPGTGKTTTVARLLALFAEQAQLAGKA------ MUL_0707|M.ulcerans_Agy99 RAAAKIALAQGLTVLTGGPGTGKTTTVARLLALFAEQAQLAGKA------ TH_1441|M.thermoresistible__bu LRDTHVELERLVHTLPAGPYQRDRGPSQWLLNMLATQTERAALVPLIDAV : : : : .*..** . . ** .. *: *. Mb0645c|M.bovis_AF2122/97 ------------RPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGD Rv0629c|M.tuberculosis_H37Rv ------------RPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGD MAV_4544|M.avium_104 ------------RPRIALAAPTGKAAARLAEAVAAEIEHLDPADRARLAG Mflv_5131|M.gilvum_PYR-GCK ------------PPRMALAAPTGKAAARLQDAVQAEVDRLSAVDRARLAG Mvan_1208|M.vanbaalenii_PYR-1 ------------PPRMALAAPTGKAAARLQDAVHAEVGKLPAVDQGRLAG MAB_0398c|M.abscessus_ATCC_199 ------------PLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAG MSMEG_1325|M.smegmatis_MC2_155 ------------SPRIALAAPTGKAAARLQEAVQLEIDQLDLIERRRLTG MMAR_0956|M.marinum_M ------------RLRIALAAPTGKAAARLHEAVQSQIDKLDAIDQQRVRG MUL_0707|M.ulcerans_Agy99 ------------RLRIALAAPTGKAAARLHEAVQSQIDKLDAIDQQRVRG TH_1441|M.thermoresistible__bu HRRMRAEKVMDFGMQMAAAARLASEHPQVGAALRQRFRVVLLDEYQDTGH ::* ** .. .:: *: .. : : Mb0645c|M.bovis_AF2122/97 LHAVTLHRLLGAKP--GARFRQDRQ----------------NRLPHNVIV Rv0629c|M.tuberculosis_H37Rv LHAVTLHRLLGAKP--GARFRQDRQ----------------NRLPHNVIV MAV_4544|M.avium_104 LTGTTLHRLLGPRPDTSVRFKHNRG----------------NRLPHDIIV Mflv_5131|M.gilvum_PYR-GCK LRATTMHRLLGSRPDTSSRFRHHRG----------------NRLPHDVIV Mvan_1208|M.vanbaalenii_PYR-1 LRATTLHRLLGSRPDTSSRFRHHRD----------------NRLPHDVIV MAB_0398c|M.abscessus_ATCC_199 LQATTLHRLLGSRPDTSSRFKHDRG----------------NRLPHDVIV MSMEG_1325|M.smegmatis_MC2_155 LHATTLHRLLGPRPDTSSRFRHHRA----------------NRLPHDVIV MMAR_0956|M.marinum_M LQATTLHRLLGSRPDTSSRFRHHRG----------------NRLPHDVIV MUL_0707|M.ulcerans_Agy99 LQATTLHRLLGSRPDTSSRFRHHRG----------------NRLPHDVIV TH_1441|M.thermoresistible__bu AQRIALSALFGGGVDDDLALTAVGDPIQSIYGWRGASATNLPRFATDFPH :: *:* . : *:. :. Mb0645c|M.bovis_AF2122/97 VDETSMVSLTLMARLAEAVR-----------PGARLILVGDADQLASVEA Rv0629c|M.tuberculosis_H37Rv VDETSMVSLTLMARLAEAVR-----------PGARLILVGDADQLASVEA MAV_4544|M.avium_104 VDETSMVSLTMMARLAEAVR-----------PDTRLILVGDPDQLASVEA Mflv_5131|M.gilvum_PYR-GCK VDETSMVSLTMMARLLEAVR-----------PDTRLLFVGDPDQLASVDA Mvan_1208|M.vanbaalenii_PYR-1 VDETSMVSLTMMARLLEAVR-----------PDTRLLFVGDPDQLASVDA MAB_0398c|M.abscessus_ATCC_199 VDETSMVSLTMMARLLEAVR-----------PQARLLLVGDPDQLASVEA MSMEG_1325|M.smegmatis_MC2_155 VDETSMVSLTMMARLLEAVR-----------PQTRLVLVGDPDQLASVEA MMAR_0956|M.marinum_M IDETSMVSLTMMARLLEAVR-----------PQTRLLLVGDPDQLASVEA MUL_0707|M.ulcerans_Agy99 IDETSMVSLTMMARLLEAVR-----------PQTRLLLVGDPDQLASVEA TH_1441|M.thermoresistible__bu SDGSPAPTLELRTSWRNPPRTLHLANAISAEARRRSVAVRALRPRPDAEP * :. :* : : :. * . * : * ...:. Mb0645c|M.bovis_AF2122/97 GAVLADLVDGFSVRDDALVAQLRTSHRFGKVIG-----TLAEAIRAGDGD Rv0629c|M.tuberculosis_H37Rv GAVLADLVDGFSVRDDALVAQLRTSHRFGKVIG-----TLAEAIRAGDGD MAV_4544|M.avium_104 GAVLADLVDGLAGRAGVRVAALATPHRFGSAIG-----ALAAAIRAGDAD Mflv_5131|M.gilvum_PYR-GCK GAVLADLVDGLGEAG---VVELTTSHRFGERIG-----ALALAIRSGDAD Mvan_1208|M.vanbaalenii_PYR-1 GAVLADLVEGLGDAG---VVELKTPHRFGETIG-----SLAEAIRAGDAD MAB_0398c|M.abscessus_ATCC_199 GAVLADLVEGLESER---VAALRTSHRFGAAIG-----ALAAAVRDGDAD MSMEG_1325|M.smegmatis_MC2_155 GAVLADLVEGLGSRG---VAELKTSHRFGESIG-----ALASAIRTGDAD MMAR_0956|M.marinum_M GAVLADLVDGLGARHDTHVAALRRLHRFGESIG-----QLAAAIRGGDAD MUL_0707|M.ulcerans_Agy99 GAVLADLVDGLGARHDTHVAALRRLHRFGESIG-----QLAAAIRGGDAD TH_1441|M.thermoresistible__bu GTIRCALLDDVQSEREWVAEQLAALYRHARDAGDTPPTAAVLVRRNADAA *:: . *::.. . * :*.. * . . * .*. Mb0645c|M.bovis_AF2122/97 AVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALA Rv0629c|M.tuberculosis_H37Rv AVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALA MAV_4544|M.avium_104 RVVELLAAGGEHIEWVDSERPADRLREVLVSHALRLRSAALLGAAQAALA Mflv_5131|M.gilvum_PYR-GCK ATVEVLRAGGDAIGWLDTDDAADALRGPLVDRAADLREAALLGDGETALR Mvan_1208|M.vanbaalenii_PYR-1 TAVQLLRAGGDAVAWLDTDDPSDALRATLVARADELRRAALLGDARAALG MAB_0398c|M.abscessus_ATCC_199 RALEVLASGDPHVEWS-TDS--EGLRDVLVPQALALRAASLSGDATAALA MSMEG_1325|M.smegmatis_MC2_155 AALAVLAAGGEHIEWV-HEDPVEQLREVVVPHAMRLRQAAILGDQREALA MMAR_0956|M.marinum_M RVVEILRAGDDHIEWINAADPTPQLRNVLLPHALELRRAGALGDTAAALA MUL_0707|M.ulcerans_Agy99 RVVEILRAGDDHIEWINAADPTPQLRNVLLPHALELRRAGALGDTAAALA TH_1441|M.thermoresistible__bu PMAQALTARGVPVEVVGLAGLLAVPEVADVVAMLRLAADPTAGSAAVRIL * : : . : * * : Mb0645c|M.bovis_AF2122/97 TLDEHRL------------------------------------------- Rv0629c|M.tuberculosis_H37Rv TLDEHRL------------------------------------------- MAV_4544|M.avium_104 TLDEHRL------------------------------------------- Mflv_5131|M.gilvum_PYR-GCK ILDGHRL------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 VLDGHRL------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 VLDEHRM------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 TLDEHRL------------------------------------------- MMAR_0956|M.marinum_M TLDEQRL------------------------------------------- MUL_0707|M.ulcerans_Agy99 TLDEQRL------------------------------------------- TH_1441|M.thermoresistible__bu TGPRWRLGARDLTALWRRAVELGTVEPPGARPDTDGVEQILAGIGPDADE *: Mb0645c|M.bovis_AF2122/97 ---------------------------------LCAHRDGPTG--VLHWN Rv0629c|M.tuberculosis_H37Rv ---------------------------------LCAHRDGPTG--VLHWN MAV_4544|M.avium_104 ---------------------------------LCAHRDGPHG--AVRWN Mflv_5131|M.gilvum_PYR-GCK ---------------------------------LCAHRRGPFG--VAHWN Mvan_1208|M.vanbaalenii_PYR-1 ---------------------------------LCAHRRGPFG--VTHWN MAB_0398c|M.abscessus_ATCC_199 ---------------------------------LCAHRHGPFG--VTHWN MSMEG_1325|M.smegmatis_MC2_155 ---------------------------------LCAHRRGPAG--VDHWN MMAR_0956|M.marinum_M ---------------------------------LCAHRRGPYG--IAHWN MUL_0707|M.ulcerans_Agy99 ---------------------------------LCAHRRGPYG--IAHWN TH_1441|M.thermoresistible__bu PCLADAICDPGDAAAYSEEGYRRITALAQELTALRAHLHHPLPDLIAEIR * ** * . . Mb0645c|M.bovis_AF2122/97 RRVQAWLAEETGQPPWTPWYAGR--------------------PLLVTAN Rv0629c|M.tuberculosis_H37Rv RRVQAWLAEETGQPPWTPWYAGR--------------------PLLVTAN MAV_4544|M.avium_104 TLVHNWIAEETGQPAWSQWYAGR--------------------PLLVTAN Mflv_5131|M.gilvum_PYR-GCK RQIERWLAERTGQSIWSQPYAGR--------------------PLLVTAN Mvan_1208|M.vanbaalenii_PYR-1 RQVERWLADKTGQPMWSQWYPGR--------------------PLLVTAN MAB_0398c|M.abscessus_ATCC_199 RQVERWITEETGEPHWAPWYAGR--------------------PILVTAN MSMEG_1325|M.smegmatis_MC2_155 RQVQRWLGEETGEPLWGSWYVGR--------------------PILVTAN MMAR_0956|M.marinum_M HQVQRWLTEATGEPIWSSWYAGR--------------------PVLVTAN MUL_0707|M.ulcerans_Agy99 HQVQRWLTEATGEPIWSSWYAGR--------------------PVLVTAN TH_1441|M.thermoresistible__bu RILGVDAEARAGQPVAAGWAGTENLDAFADVVAEFAVRPNATVPALLGYL : :*:. . * *: Mb0645c|M.bovis_AF2122/97 DYGLRVYNGDTGVVLAG--------------------------------- Rv0629c|M.tuberculosis_H37Rv DYGLRVYNGDTGVVLAG--------------------------------- MAV_4544|M.avium_104 DYGLRLYNGDTGVTVAG--------------------------------- Mflv_5131|M.gilvum_PYR-GCK DYGLGVYNGDTGVVVAA--------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 DYGLGVYNGDTGVVVAA--------------------------------- MAB_0398c|M.abscessus_ATCC_199 DYGLRLYNGDTGVTVAG--------------------------------- MSMEG_1325|M.smegmatis_MC2_155 DYGLKLYNGDTGVVVAT--------------------------------- MMAR_0956|M.marinum_M DYGLGVYNGDTGVAVLDGTN--------------------------RAAA MUL_0707|M.ulcerans_Agy99 DYGLGVYNGDTGVAVLDGTN--------------------------RAAA TH_1441|M.thermoresistible__bu SAAMEVENGLAPADVTVATDRVQILTVHAAKGLEWEVVAVPHLSRRVFPS . .: : ** : . : Mb0645c|M.bovis_AF2122/97 PTGLRAVISGASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQ Rv0629c|M.tuberculosis_H37Rv PTGLRAVISGASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQ MAV_4544|M.avium_104 ADGLRAVIAGAAGPLDFATSRLGEVETMHAMTIHKSQGSQADEVTVLIPP Mflv_5131|M.gilvum_PYR-GCK PEGLRAHIGTPASSRELAVGRLGEVETMFAMTIHKSQGSQADEVTVLMPP Mvan_1208|M.vanbaalenii_PYR-1 PDGLRAHVG----SLQFAPGRLGEVETMFAMTIHKSQGSQADEVTVLLPP MAB_0398c|M.abscessus_ATCC_199 PDGLRAVIG----AASFATSRLVEVETMHAMTIHKSQGSQANEVTVLLPS MSMEG_1325|M.smegmatis_MC2_155 PDGMRAVIGD---AGTFATGRLTDVETMHAMTIHKSQGSQADEVTVLLPS MMAR_0956|M.marinum_M PGALRVLIAGAQEPLKFATSRLSDVETMHAMTIHKSQGSQADDVTVLLPP MUL_0707|M.ulcerans_Agy99 PGALRVVIAGAQEPLKFATSRLSDVETMHAMTIHKSQGSQADDVTVLLPP TH_1441|M.thermoresistible__bu TASPRTWLTDAGELPPLLRGDRATTSEHGVPVLDTADVNDRKALSDKIAE . . *. : . . .. . .:..:: .: . :: :. Mb0645c|M.bovis_AF2122/97 EDSRLLTR------ELLYTAVARAKRKVRVVGSEA--------------- Rv0629c|M.tuberculosis_H37Rv EDSRLLTR------ELLYTAVTRAKRKVRVVGSEA--------------- MAV_4544|M.avium_104 EDSRLLTR------ELFYTAVTRAKSRVRVVGPEA--------------- Mflv_5131|M.gilvum_PYR-GCK QDSRLLTR------ELFYTAVTRAKERVQVVGTEA--------------- Mvan_1208|M.vanbaalenii_PYR-1 QDSRLLTR------ELFYTAVTRAKKHVRVVGTEA--------------- MAB_0398c|M.abscessus_ATCC_199 EDSRLLTR------ELFYTAVTRAKQRVRVVGSEA--------------- MSMEG_1325|M.smegmatis_MC2_155 EDSRLLTR------ELFYTAVTRAKTRVRVVGAEA--------------- MMAR_0956|M.marinum_M ADSRLLTR------ELFYTAVTRAARKVRIVGPEC--------------- MUL_0707|M.ulcerans_Agy99 ADSRLLTR------ELFYTAVTRAARKVRIVGPEC--------------- TH_1441|M.thermoresistible__bu HKNRLAQRRTDEERRLLYVAVTRAEDTLLVSGHHWGATESKPRGPSEFLL ..** * .*:*.**:** : : * . Mb0645c|M.bovis_AF2122/97 SVRAAIARRAVR--------------ASGLRMRLQSTGCG---------- Rv0629c|M.tuberculosis_H37Rv SVRAAIARRAVR--------------ASGLRMRLQSTGCG---------- MAV_4544|M.avium_104 SVRAAIERRAIR--------------ATGLRQRLRVVG------------ Mflv_5131|M.gilvum_PYR-GCK SVRAAVGRRAVR--------------ASGLARRLSTAR------------ Mvan_1208|M.vanbaalenii_PYR-1 SVRTAIGRRATR--------------ASGLAQRLRTRP------------ MAB_0398c|M.abscessus_ATCC_199 EVRAAIQRQAVR--------------ASGLGRRLRHSPN----------- MSMEG_1325|M.smegmatis_MC2_155 EVRAAIERQAVR--------------ATGLRKRLRPAGV----------- MMAR_0956|M.marinum_M DVRAAIARRAIR--------------ATGLRSRLQP-------------- MUL_0707|M.ulcerans_Agy99 DVRAAIARRAIR--------------ATGLRSRLQP-------------- TH_1441|M.thermoresistible__bu EIKDVIDRSAEAGDPCGTIDLWAPEPPDGTPNPLRDKAFEVLWPAPPXXX .:: .: * * . * * Mb0645c|M.bovis_AF2122/97 -------------------------------------------------- Rv0629c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4544|M.avium_104 -------------------------------------------------- Mflv_5131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0956|M.marinum_M -------------------------------------------------- MUL_0707|M.ulcerans_Agy99 -------------------------------------------------- TH_1441|M.thermoresistible__bu PAGPPPPVSPRITTPSAGGAQPNRRRLIAGVAGVAAVAVLGGLAFWLLSP Mb0645c|M.bovis_AF2122/97 -------------------------------------------------- Rv0629c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4544|M.avium_104 -------------------------------------------------- Mflv_5131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0956|M.marinum_M -------------------------------------------------- MUL_0707|M.ulcerans_Agy99 -------------------------------------------------- TH_1441|M.thermoresistible__bu SGTDQADGARADDTAETTSPPRDTAAENRLLTMLPPGYSAGACGPVPAPE Mb0645c|M.bovis_AF2122/97 -------------------------------------------------- Rv0629c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4544|M.avium_104 -------------------------------------------------- Mflv_5131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0956|M.marinum_M -------------------------------------------------- MUL_0707|M.ulcerans_Agy99 -------------------------------------------------- TH_1441|M.thermoresistible__bu GALAQVVCRENTDPGGPPTATYTLARDEAAMQRAFDEIIAASATVNCPNF Mb0645c|M.bovis_AF2122/97 -------------------------------------------------- Rv0629c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4544|M.avium_104 -------------------------------------------------- Mflv_5131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0956|M.marinum_M -------------------------------------------------- MUL_0707|M.ulcerans_Agy99 -------------------------------------------------- TH_1441|M.thermoresistible__bu IQSPGPWRRNATPDRISGTLFCGIQQNEPLVAWTDDANLVVSAVHSGPQG Mb0645c|M.bovis_AF2122/97 -------------- Rv0629c|M.tuberculosis_H37Rv -------------- MAV_4544|M.avium_104 -------------- Mflv_5131|M.gilvum_PYR-GCK -------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------- MAB_0398c|M.abscessus_ATCC_199 -------------- MSMEG_1325|M.smegmatis_MC2_155 -------------- MMAR_0956|M.marinum_M -------------- MUL_0707|M.ulcerans_Agy99 -------------- TH_1441|M.thermoresistible__bu PTLDELYAWWTTHS