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M. bovis AF2122 / 97 Mb0645c (recD)

annotation: exonuclease V alpha chain
coordinates: 721251 - 722978
length: 575

VKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLSI
ARVAGHDDLPWPDPADWLAAVRASPLLADPPVLHLYDDRLLYLDRYWREEEQVCADLLALLTSRRPAGVP
DLRRLFPTGFDEQRRAAEIALSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEPRPRIALAAPTGKA
AARLAEAVRREMAKLDATDRARLGDLHAVTLHRLLGAKPGARFRQDRQNRLPHNVIVVDETSMVSLTLMA
RLAEAVRPGARLILVGDADQLASVEAGAVLADLVDGFSVRDDALVAQLRTSHRFGKVIGTLAEAIRAGDG
DAVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVL
HWNRRVQAWLAEETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTGLRAVISGASGPLDVATG
RLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVARAKRKVRVVGSEASVRAAIARRAV
RASGLRMRLQSTGCG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0645crecD-100% (575)exonuclease V alpha chain
M. bovis AF2122 / 97Mb1283c-5e-0824.53% (428) hypothetical protein Mb1283c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5131-0.066.12% (552) exodeoxyribonuclease V, alpha subunit
M. tuberculosis H37RvRv0629crecD0.099.83% (575) exonuclease V alpha chain
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0398c-0.067.62% (559) exodeoxyribonuclease V, alpha subunit (RecD)
M. marinum MMMAR_0956recD0.066.84% (573) exodeoxyribonuclease V (alpha chain), RecD
M. avium 104MAV_4544recD0.071.40% (563) exodeoxyribonuclease V, alpha subunit
M. smegmatis MC2 155MSMEG_1325recD0.070.04% (554) exodeoxyribonuclease V, alpha subunit
M. thermoresistible (build 8)TH_1441-8e-0537.86% (103) PROBABLE ATP-DEPENDENT DNA HELICASE
M. ulcerans Agy99MUL_0707recD0.066.84% (573) exodeoxyribonuclease V (alpha chain), RecD
M. vanbaalenii PYR-1Mvan_1208-0.066.31% (558) exodeoxyribonuclease V, alpha subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mb0645c|M.bovis_AF2122/97           -----------------------------MKLTDVDFAVEASGMVRAFNQ
Rv0629c|M.tuberculosis_H37Rv        -----------------------------MKLTDVDFAVEASGMVRAFNQ
MAV_4544|M.avium_104                ------------------------------MLPER---VFDAGPLRPFAD
Mflv_5131|M.gilvum_PYR-GCK          ------------------------------------------MSLDAF--
Mvan_1208|M.vanbaalenii_PYR-1       ------------------------------------------MTVEAF--
MAB_0398c|M.abscessus_ATCC_199      -----------------------------------------MSLVEAF--
MSMEG_1325|M.smegmatis_MC2_155      -----------------------------------------MSLLEAF--
MMAR_0956|M.marinum_M               ------------------------MTIDVVDPADWRQAASASGPLRTFNE
MUL_0707|M.ulcerans_Agy99           ------------------------MTIEVVDPADWRQAASASGPLRTFNE
TH_1441|M.thermoresistible__bu      LSGAGRAGRIGAAVTARHSPADLAEALGLFPPTEEQAAVIAAPPGPLVVI
                                                                                   .  

Mb0645c|M.bovis_AF2122/97           AGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLS-I
Rv0629c|M.tuberculosis_H37Rv        AGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLS-I
MAV_4544|M.avium_104                AGIFEAADIHVAQRLTALTGESDDRVALAVALLVRALRGGSVCVDLRA-V
Mflv_5131|M.gilvum_PYR-GCK          AEVFEPADIHVAQRLTELGRDSDPTVALAVALAVRAVRSGSVCVDLRT-V
Mvan_1208|M.vanbaalenii_PYR-1       SELFEPADLHVAQRLTTLGKEGDDSVALAVALAVRALRGGSVCVDLRA-I
MAB_0398c|M.abscessus_ATCC_199      GEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRA-V
MSMEG_1325|M.smegmatis_MC2_155      AEILEPADVHVAQRLTVLADEPDASVELAVALAVRALRGGSVCVDLRS-V
MMAR_0956|M.marinum_M               AGVIDAADVHVAQRLAAMSGESDPVVLLAIAFVVRALRGGSVCVDLST-I
MUL_0707|M.ulcerans_Agy99           ARVIDAADVHVAQRLAAMSGESDPVVLLAIAFVVRALRGGSVCVDLST-I
TH_1441|M.thermoresistible__bu      AGAGAGKTETMAARVVWLVANGYARPDQVLGLTFTRKAAGQLLRRVRSRL
                                    .         :* *:  :  :       .:.. .    .*.:   : : :

Mb0645c|M.bovis_AF2122/97           ARVAGHDDLPWPDPADWLAA---------VRASPLLADPPVLHLYDDR-L
Rv0629c|M.tuberculosis_H37Rv        ARVAGHDDLPWPDPADWLAA---------VRASPLLADPPVLHLYDDR-L
MAV_4544|M.avium_104                PAQVGAADLPWPAAGDWLAA---------VRASPLLGPPPVLRFFGD--L
Mflv_5131|M.gilvum_PYR-GCK          AAQVGVPELPWPDPDGWLST---------VGASPLAEHK-VVRLDGD--L
Mvan_1208|M.vanbaalenii_PYR-1       ATQVGMPELPWPEPDRWLAA---------VGASPLADER-VLRMHGD--L
MAB_0398c|M.abscessus_ATCC_199      AAQVDMPSLPWPAADDWLAA---------VRASPLAGEPPVLRLFGD--L
MSMEG_1325|M.smegmatis_MC2_155      AGQVELPDLPWPDPDAWLAA---------LAASPLLGQPPVLRLFGD--L
MMAR_0956|M.marinum_M               EAQVGIADLPWPAAGEWLAA---------VRASPLVGSPAVLRLHEDN-L
MUL_0707|M.ulcerans_Agy99           EAQVGIADLPWPAAGEWLAA---------VRASPLVGSPAVLRLHEDN-L
TH_1441|M.thermoresistible__bu      ARLAGTGLVPANSAPDWTTESVTVSTYHAFAGTLLREHGLLLPVEPDTRL
                                       .    :*   .  * :          . .: *     :: .  *  *

Mb0645c|M.bovis_AF2122/97           LYLDRYWREEEQVCADLLALLT--SRRPAGVPDLRRLFPTGFD-----EQ
Rv0629c|M.tuberculosis_H37Rv        LYLDRYWREEEQVCADLLALLT--SRRPAGVPDLRRLFPTGFD-----EQ
MAV_4544|M.avium_104                LYFDRYWLEEEQVCTDLLALSA--PAGDVESSCYERLFPPGYE-----EQ
Mflv_5131|M.gilvum_PYR-GCK          LYLDRYWREEEQVRDDVVALLS--SPPRTAVPGLERLFPAGWE-----EQ
Mvan_1208|M.vanbaalenii_PYR-1       LYLDRYWREEQQVCDDVLALLA--SPLPATAPSIERLFPAGWE-----EQ
MAB_0398c|M.abscessus_ATCC_199      LYLDRYWREEQQVCTDVQALMAA-AQPRTEVPTYERLFPQGFE-----EQ
MSMEG_1325|M.smegmatis_MC2_155      LYLDRYWLEEQQVCDDVLALVS--ARPGGAVPDVSRLFGAGFE-----EQ
MMAR_0956|M.marinum_M               VYLDRYWREEQQVADDILALLAARASASGPAIEVNRLFPPGYE-----EQ
MUL_0707|M.ulcerans_Agy99           VYLDRYWREEQQVADDILALLAARASASGPAIEVNRLFPPGYE-----EQ
TH_1441|M.thermoresistible__bu      IGETELWQLAYRVVCEHPGPLDTDKTPAAITAMVLRLAGQLAEHLVDTDQ
                                    :   . *    :*  :  .                **     :     :*

Mb0645c|M.bovis_AF2122/97           RRAAEIALSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEP------
Rv0629c|M.tuberculosis_H37Rv        RRAAEIALSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEP------
MAV_4544|M.avium_104                RAAARIAVSQALTVLTGGPGTGKTTTVARLLALLVEQAERAGEP------
Mflv_5131|M.gilvum_PYR-GCK          RAAAEAALTRSLTVLTGGPGTGKTTTVARLLAAFAEQAELAGGP------
Mvan_1208|M.vanbaalenii_PYR-1       REAAKVALRQSLTVLTGGPGTGKTTTVARLLASIAEQAESAGGA------
MAB_0398c|M.abscessus_ATCC_199      RAAADIALSQGLTVLTGGPGTGKTTTVARLLALLADQASSASAA------
MSMEG_1325|M.smegmatis_MC2_155      RAAAKVALSQGLTVLTGGPGTGKTTTVARLLALLAEQAALAGKP------
MMAR_0956|M.marinum_M               RAAAKIALAQGLTVLTGGPGTGKTTTVARLLALFAEQAQLAGKA------
MUL_0707|M.ulcerans_Agy99           RAAAKIALAQGLTVLTGGPGTGKTTTVARLLALFAEQAQLAGKA------
TH_1441|M.thermoresistible__bu      LRDTHVELERLVHTLPAGPYQRDRGPSQWLLNMLATQTERAALVPLIDAV
                                       :   : : : .*..**   .  .   **  .. *:  *.        

Mb0645c|M.bovis_AF2122/97           ------------RPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGD
Rv0629c|M.tuberculosis_H37Rv        ------------RPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGD
MAV_4544|M.avium_104                ------------RPRIALAAPTGKAAARLAEAVAAEIEHLDPADRARLAG
Mflv_5131|M.gilvum_PYR-GCK          ------------PPRMALAAPTGKAAARLQDAVQAEVDRLSAVDRARLAG
Mvan_1208|M.vanbaalenii_PYR-1       ------------PPRMALAAPTGKAAARLQDAVHAEVGKLPAVDQGRLAG
MAB_0398c|M.abscessus_ATCC_199      ------------PLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAG
MSMEG_1325|M.smegmatis_MC2_155      ------------SPRIALAAPTGKAAARLQEAVQLEIDQLDLIERRRLTG
MMAR_0956|M.marinum_M               ------------RLRIALAAPTGKAAARLHEAVQSQIDKLDAIDQQRVRG
MUL_0707|M.ulcerans_Agy99           ------------RLRIALAAPTGKAAARLHEAVQSQIDKLDAIDQQRVRG
TH_1441|M.thermoresistible__bu      HRRMRAEKVMDFGMQMAAAARLASEHPQVGAALRQRFRVVLLDEYQDTGH
                                                  ::* **  ..  .::  *:  ..  :   :      

Mb0645c|M.bovis_AF2122/97           LHAVTLHRLLGAKP--GARFRQDRQ----------------NRLPHNVIV
Rv0629c|M.tuberculosis_H37Rv        LHAVTLHRLLGAKP--GARFRQDRQ----------------NRLPHNVIV
MAV_4544|M.avium_104                LTGTTLHRLLGPRPDTSVRFKHNRG----------------NRLPHDIIV
Mflv_5131|M.gilvum_PYR-GCK          LRATTMHRLLGSRPDTSSRFRHHRG----------------NRLPHDVIV
Mvan_1208|M.vanbaalenii_PYR-1       LRATTLHRLLGSRPDTSSRFRHHRD----------------NRLPHDVIV
MAB_0398c|M.abscessus_ATCC_199      LQATTLHRLLGSRPDTSSRFKHDRG----------------NRLPHDVIV
MSMEG_1325|M.smegmatis_MC2_155      LHATTLHRLLGPRPDTSSRFRHHRA----------------NRLPHDVIV
MMAR_0956|M.marinum_M               LQATTLHRLLGSRPDTSSRFRHHRG----------------NRLPHDVIV
MUL_0707|M.ulcerans_Agy99           LQATTLHRLLGSRPDTSSRFRHHRG----------------NRLPHDVIV
TH_1441|M.thermoresistible__bu      AQRIALSALFGGGVDDDLALTAVGDPIQSIYGWRGASATNLPRFATDFPH
                                        ::  *:*     .  :                      *:. :.  

Mb0645c|M.bovis_AF2122/97           VDETSMVSLTLMARLAEAVR-----------PGARLILVGDADQLASVEA
Rv0629c|M.tuberculosis_H37Rv        VDETSMVSLTLMARLAEAVR-----------PGARLILVGDADQLASVEA
MAV_4544|M.avium_104                VDETSMVSLTMMARLAEAVR-----------PDTRLILVGDPDQLASVEA
Mflv_5131|M.gilvum_PYR-GCK          VDETSMVSLTMMARLLEAVR-----------PDTRLLFVGDPDQLASVDA
Mvan_1208|M.vanbaalenii_PYR-1       VDETSMVSLTMMARLLEAVR-----------PDTRLLFVGDPDQLASVDA
MAB_0398c|M.abscessus_ATCC_199      VDETSMVSLTMMARLLEAVR-----------PQARLLLVGDPDQLASVEA
MSMEG_1325|M.smegmatis_MC2_155      VDETSMVSLTMMARLLEAVR-----------PQTRLVLVGDPDQLASVEA
MMAR_0956|M.marinum_M               IDETSMVSLTMMARLLEAVR-----------PQTRLLLVGDPDQLASVEA
MUL_0707|M.ulcerans_Agy99           IDETSMVSLTMMARLLEAVR-----------PQTRLLLVGDPDQLASVEA
TH_1441|M.thermoresistible__bu      SDGSPAPTLELRTSWRNPPRTLHLANAISAEARRRSVAVRALRPRPDAEP
                                     * :.  :* : :   :. *           .  * : *      ...:.

Mb0645c|M.bovis_AF2122/97           GAVLADLVDGFSVRDDALVAQLRTSHRFGKVIG-----TLAEAIRAGDGD
Rv0629c|M.tuberculosis_H37Rv        GAVLADLVDGFSVRDDALVAQLRTSHRFGKVIG-----TLAEAIRAGDGD
MAV_4544|M.avium_104                GAVLADLVDGLAGRAGVRVAALATPHRFGSAIG-----ALAAAIRAGDAD
Mflv_5131|M.gilvum_PYR-GCK          GAVLADLVDGLGEAG---VVELTTSHRFGERIG-----ALALAIRSGDAD
Mvan_1208|M.vanbaalenii_PYR-1       GAVLADLVEGLGDAG---VVELKTPHRFGETIG-----SLAEAIRAGDAD
MAB_0398c|M.abscessus_ATCC_199      GAVLADLVEGLESER---VAALRTSHRFGAAIG-----ALAAAVRDGDAD
MSMEG_1325|M.smegmatis_MC2_155      GAVLADLVEGLGSRG---VAELKTSHRFGESIG-----ALASAIRTGDAD
MMAR_0956|M.marinum_M               GAVLADLVDGLGARHDTHVAALRRLHRFGESIG-----QLAAAIRGGDAD
MUL_0707|M.ulcerans_Agy99           GAVLADLVDGLGARHDTHVAALRRLHRFGESIG-----QLAAAIRGGDAD
TH_1441|M.thermoresistible__bu      GTIRCALLDDVQSEREWVAEQLAALYRHARDAGDTPPTAAVLVRRNADAA
                                    *:: . *::..       .  *   :*..   *       . . * .*. 

Mb0645c|M.bovis_AF2122/97           AVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALA
Rv0629c|M.tuberculosis_H37Rv        AVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALA
MAV_4544|M.avium_104                RVVELLAAGGEHIEWVDSERPADRLREVLVSHALRLRSAALLGAAQAALA
Mflv_5131|M.gilvum_PYR-GCK          ATVEVLRAGGDAIGWLDTDDAADALRGPLVDRAADLREAALLGDGETALR
Mvan_1208|M.vanbaalenii_PYR-1       TAVQLLRAGGDAVAWLDTDDPSDALRATLVARADELRRAALLGDARAALG
MAB_0398c|M.abscessus_ATCC_199      RALEVLASGDPHVEWS-TDS--EGLRDVLVPQALALRAASLSGDATAALA
MSMEG_1325|M.smegmatis_MC2_155      AALAVLAAGGEHIEWV-HEDPVEQLREVVVPHAMRLRQAAILGDQREALA
MMAR_0956|M.marinum_M               RVVEILRAGDDHIEWINAADPTPQLRNVLLPHALELRRAGALGDTAAALA
MUL_0707|M.ulcerans_Agy99           RVVEILRAGDDHIEWINAADPTPQLRNVLLPHALELRRAGALGDTAAALA
TH_1441|M.thermoresistible__bu      PMAQALTARGVPVEVVGLAGLLAVPEVADVVAMLRLAADPTAGSAAVRIL
                                         * :    :            .   :     *      *     : 

Mb0645c|M.bovis_AF2122/97           TLDEHRL-------------------------------------------
Rv0629c|M.tuberculosis_H37Rv        TLDEHRL-------------------------------------------
MAV_4544|M.avium_104                TLDEHRL-------------------------------------------
Mflv_5131|M.gilvum_PYR-GCK          ILDGHRL-------------------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       VLDGHRL-------------------------------------------
MAB_0398c|M.abscessus_ATCC_199      VLDEHRM-------------------------------------------
MSMEG_1325|M.smegmatis_MC2_155      TLDEHRL-------------------------------------------
MMAR_0956|M.marinum_M               TLDEQRL-------------------------------------------
MUL_0707|M.ulcerans_Agy99           TLDEQRL-------------------------------------------
TH_1441|M.thermoresistible__bu      TGPRWRLGARDLTALWRRAVELGTVEPPGARPDTDGVEQILAGIGPDADE
                                         *:                                           

Mb0645c|M.bovis_AF2122/97           ---------------------------------LCAHRDGPTG--VLHWN
Rv0629c|M.tuberculosis_H37Rv        ---------------------------------LCAHRDGPTG--VLHWN
MAV_4544|M.avium_104                ---------------------------------LCAHRDGPHG--AVRWN
Mflv_5131|M.gilvum_PYR-GCK          ---------------------------------LCAHRRGPFG--VAHWN
Mvan_1208|M.vanbaalenii_PYR-1       ---------------------------------LCAHRRGPFG--VTHWN
MAB_0398c|M.abscessus_ATCC_199      ---------------------------------LCAHRHGPFG--VTHWN
MSMEG_1325|M.smegmatis_MC2_155      ---------------------------------LCAHRRGPAG--VDHWN
MMAR_0956|M.marinum_M               ---------------------------------LCAHRRGPYG--IAHWN
MUL_0707|M.ulcerans_Agy99           ---------------------------------LCAHRRGPYG--IAHWN
TH_1441|M.thermoresistible__bu      PCLADAICDPGDAAAYSEEGYRRITALAQELTALRAHLHHPLPDLIAEIR
                                                                     * **   *      . .

Mb0645c|M.bovis_AF2122/97           RRVQAWLAEETGQPPWTPWYAGR--------------------PLLVTAN
Rv0629c|M.tuberculosis_H37Rv        RRVQAWLAEETGQPPWTPWYAGR--------------------PLLVTAN
MAV_4544|M.avium_104                TLVHNWIAEETGQPAWSQWYAGR--------------------PLLVTAN
Mflv_5131|M.gilvum_PYR-GCK          RQIERWLAERTGQSIWSQPYAGR--------------------PLLVTAN
Mvan_1208|M.vanbaalenii_PYR-1       RQVERWLADKTGQPMWSQWYPGR--------------------PLLVTAN
MAB_0398c|M.abscessus_ATCC_199      RQVERWITEETGEPHWAPWYAGR--------------------PILVTAN
MSMEG_1325|M.smegmatis_MC2_155      RQVQRWLGEETGEPLWGSWYVGR--------------------PILVTAN
MMAR_0956|M.marinum_M               HQVQRWLTEATGEPIWSSWYAGR--------------------PVLVTAN
MUL_0707|M.ulcerans_Agy99           HQVQRWLTEATGEPIWSSWYAGR--------------------PVLVTAN
TH_1441|M.thermoresistible__bu      RILGVDAEARAGQPVAAGWAGTENLDAFADVVAEFAVRPNATVPALLGYL
                                      :       :*:.        .                    * *:   

Mb0645c|M.bovis_AF2122/97           DYGLRVYNGDTGVVLAG---------------------------------
Rv0629c|M.tuberculosis_H37Rv        DYGLRVYNGDTGVVLAG---------------------------------
MAV_4544|M.avium_104                DYGLRLYNGDTGVTVAG---------------------------------
Mflv_5131|M.gilvum_PYR-GCK          DYGLGVYNGDTGVVVAA---------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       DYGLGVYNGDTGVVVAA---------------------------------
MAB_0398c|M.abscessus_ATCC_199      DYGLRLYNGDTGVTVAG---------------------------------
MSMEG_1325|M.smegmatis_MC2_155      DYGLKLYNGDTGVVVAT---------------------------------
MMAR_0956|M.marinum_M               DYGLGVYNGDTGVAVLDGTN--------------------------RAAA
MUL_0707|M.ulcerans_Agy99           DYGLGVYNGDTGVAVLDGTN--------------------------RAAA
TH_1441|M.thermoresistible__bu      SAAMEVENGLAPADVTVATDRVQILTVHAAKGLEWEVVAVPHLSRRVFPS
                                    . .: : ** : . :                                   

Mb0645c|M.bovis_AF2122/97           PTGLRAVISGASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQ
Rv0629c|M.tuberculosis_H37Rv        PTGLRAVISGASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQ
MAV_4544|M.avium_104                ADGLRAVIAGAAGPLDFATSRLGEVETMHAMTIHKSQGSQADEVTVLIPP
Mflv_5131|M.gilvum_PYR-GCK          PEGLRAHIGTPASSRELAVGRLGEVETMFAMTIHKSQGSQADEVTVLMPP
Mvan_1208|M.vanbaalenii_PYR-1       PDGLRAHVG----SLQFAPGRLGEVETMFAMTIHKSQGSQADEVTVLLPP
MAB_0398c|M.abscessus_ATCC_199      PDGLRAVIG----AASFATSRLVEVETMHAMTIHKSQGSQANEVTVLLPS
MSMEG_1325|M.smegmatis_MC2_155      PDGMRAVIGD---AGTFATGRLTDVETMHAMTIHKSQGSQADEVTVLLPS
MMAR_0956|M.marinum_M               PGALRVLIAGAQEPLKFATSRLSDVETMHAMTIHKSQGSQADDVTVLLPP
MUL_0707|M.ulcerans_Agy99           PGALRVVIAGAQEPLKFATSRLSDVETMHAMTIHKSQGSQADDVTVLLPP
TH_1441|M.thermoresistible__bu      TASPRTWLTDAGELPPLLRGDRATTSEHGVPVLDTADVNDRKALSDKIAE
                                    . . *. :        .  .    ..   . .:..:: .: . ::  :. 

Mb0645c|M.bovis_AF2122/97           EDSRLLTR------ELLYTAVARAKRKVRVVGSEA---------------
Rv0629c|M.tuberculosis_H37Rv        EDSRLLTR------ELLYTAVTRAKRKVRVVGSEA---------------
MAV_4544|M.avium_104                EDSRLLTR------ELFYTAVTRAKSRVRVVGPEA---------------
Mflv_5131|M.gilvum_PYR-GCK          QDSRLLTR------ELFYTAVTRAKERVQVVGTEA---------------
Mvan_1208|M.vanbaalenii_PYR-1       QDSRLLTR------ELFYTAVTRAKKHVRVVGTEA---------------
MAB_0398c|M.abscessus_ATCC_199      EDSRLLTR------ELFYTAVTRAKQRVRVVGSEA---------------
MSMEG_1325|M.smegmatis_MC2_155      EDSRLLTR------ELFYTAVTRAKTRVRVVGAEA---------------
MMAR_0956|M.marinum_M               ADSRLLTR------ELFYTAVTRAARKVRIVGPEC---------------
MUL_0707|M.ulcerans_Agy99           ADSRLLTR------ELFYTAVTRAARKVRIVGPEC---------------
TH_1441|M.thermoresistible__bu      HKNRLAQRRTDEERRLLYVAVTRAEDTLLVSGHHWGATESKPRGPSEFLL
                                     ..**  *      .*:*.**:**   : : * .                

Mb0645c|M.bovis_AF2122/97           SVRAAIARRAVR--------------ASGLRMRLQSTGCG----------
Rv0629c|M.tuberculosis_H37Rv        SVRAAIARRAVR--------------ASGLRMRLQSTGCG----------
MAV_4544|M.avium_104                SVRAAIERRAIR--------------ATGLRQRLRVVG------------
Mflv_5131|M.gilvum_PYR-GCK          SVRAAVGRRAVR--------------ASGLARRLSTAR------------
Mvan_1208|M.vanbaalenii_PYR-1       SVRTAIGRRATR--------------ASGLAQRLRTRP------------
MAB_0398c|M.abscessus_ATCC_199      EVRAAIQRQAVR--------------ASGLGRRLRHSPN-----------
MSMEG_1325|M.smegmatis_MC2_155      EVRAAIERQAVR--------------ATGLRKRLRPAGV-----------
MMAR_0956|M.marinum_M               DVRAAIARRAIR--------------ATGLRSRLQP--------------
MUL_0707|M.ulcerans_Agy99           DVRAAIARRAIR--------------ATGLRSRLQP--------------
TH_1441|M.thermoresistible__bu      EIKDVIDRSAEAGDPCGTIDLWAPEPPDGTPNPLRDKAFEVLWPAPPXXX
                                    .:: .: * *                . *    *                

Mb0645c|M.bovis_AF2122/97           --------------------------------------------------
Rv0629c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4544|M.avium_104                --------------------------------------------------
Mflv_5131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0398c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_1325|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0956|M.marinum_M               --------------------------------------------------
MUL_0707|M.ulcerans_Agy99           --------------------------------------------------
TH_1441|M.thermoresistible__bu      PAGPPPPVSPRITTPSAGGAQPNRRRLIAGVAGVAAVAVLGGLAFWLLSP
                                                                                      

Mb0645c|M.bovis_AF2122/97           --------------------------------------------------
Rv0629c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4544|M.avium_104                --------------------------------------------------
Mflv_5131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0398c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_1325|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0956|M.marinum_M               --------------------------------------------------
MUL_0707|M.ulcerans_Agy99           --------------------------------------------------
TH_1441|M.thermoresistible__bu      SGTDQADGARADDTAETTSPPRDTAAENRLLTMLPPGYSAGACGPVPAPE
                                                                                      

Mb0645c|M.bovis_AF2122/97           --------------------------------------------------
Rv0629c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4544|M.avium_104                --------------------------------------------------
Mflv_5131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0398c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_1325|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0956|M.marinum_M               --------------------------------------------------
MUL_0707|M.ulcerans_Agy99           --------------------------------------------------
TH_1441|M.thermoresistible__bu      GALAQVVCRENTDPGGPPTATYTLARDEAAMQRAFDEIIAASATVNCPNF
                                                                                      

Mb0645c|M.bovis_AF2122/97           --------------------------------------------------
Rv0629c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4544|M.avium_104                --------------------------------------------------
Mflv_5131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0398c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_1325|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0956|M.marinum_M               --------------------------------------------------
MUL_0707|M.ulcerans_Agy99           --------------------------------------------------
TH_1441|M.thermoresistible__bu      IQSPGPWRRNATPDRISGTLFCGIQQNEPLVAWTDDANLVVSAVHSGPQG
                                                                                      

Mb0645c|M.bovis_AF2122/97           --------------
Rv0629c|M.tuberculosis_H37Rv        --------------
MAV_4544|M.avium_104                --------------
Mflv_5131|M.gilvum_PYR-GCK          --------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------
MAB_0398c|M.abscessus_ATCC_199      --------------
MSMEG_1325|M.smegmatis_MC2_155      --------------
MMAR_0956|M.marinum_M               --------------
MUL_0707|M.ulcerans_Agy99           --------------
TH_1441|M.thermoresistible__bu      PTLDELYAWWTTHS