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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1441 | - | 100% (1065) | PROBABLE ATP-DEPENDENT DNA HELICASE | |
M. thermoresistible (build 8) | TH_1135 | uvrD2 | 8e-36 | 29.92% (498) | PROBABLE ATP-DEPENDENT DNA HELICASE II UVRD2 |
M. thermoresistible (build 8) | TH_3022 | - | 2e-06 | 24.88% (414) | PUTATIVE acyl transferase domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3226c | - | 0.0 | 72.08% (849) | ATP-dependent DNA helicase |
M. gilvum PYR-GCK | Mflv_4665 | - | 0.0 | 76.79% (840) | UvrD/REP helicase |
M. tuberculosis H37Rv | Rv3201c | - | 0.0 | 72.08% (849) | ATP-dependent DNA helicase |
M. leprae Br4923 | MLBr_00153 | uvrD | 2e-40 | 25.41% (799) | putative ATP-dependent DNA helicase |
M. abscessus ATCC 19977 | MAB_3515c | - | 0.0 | 64.47% (836) | ATP-dependent DNA helicase |
M. marinum M | MMAR_1359 | - | 0.0 | 71.16% (853) | ATP-dependent DNA helicase |
M. avium 104 | MAV_4147 | - | 0.0 | 72.56% (849) | superfamily protein I DNA and RNA helicases |
M. smegmatis MC2 155 | MSMEG_1943 | - | 0.0 | 78.82% (831) | ATP-dependent DNA helicase |
M. ulcerans Agy99 | MUL_2520 | - | 0.0 | 70.81% (853) | ATP-dependent DNA helicase |
M. vanbaalenii PYR-1 | Mvan_1802 | - | 0.0 | 75.58% (860) | UvrD/REP helicase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3226c|M.bovis_AF2122/97 --------MTQTAAPARYSPAELACALGLFPPTAEQAAVIAAPPGPLVVI Rv3201c|M.tuberculosis_H37Rv --------MTQTAAPARYSPAELACALGLFPPTAEQAAVIAAPPGPLVVI MMAR_1359|M.marinum_M -------------MNPRYSPDEIASALGIFPPTDEQAAVIAAPPGPLVVI MUL_2520|M.ulcerans_Agy99 -------------MNPRYSPDEIASALGIFPPTDEQAAVIAAPPGPLVVI MAV_4147|M.avium_104 -------------MSDRYSPRELACALGLFPPTEEQAAVIAAPPGPLVVI Mflv_4665|M.gilvum_PYR-GCK ------------MSTPLYSPAELSRALGLFEPTEEQAAVIAAPPGPLVVI Mvan_1802|M.vanbaalenii_PYR-1 ------------MTTPRYSPAELSRALGLFEPTDEQAAVIAAEPGPLVVI MSMEG_1943|M.smegmatis_MC2_155 -------------MQARYSPVELSAALGLFPPTDEQAAVIAAPPGPLVVI TH_1441|M.thermoresistible__bu LSGAGRAGRIGAAVTARHSPADLAEALGLFPPTEEQAAVIAAPPGPLVVI MAB_3515c|M.abscessus_ATCC_199 --------------MNAYSPAELSRVLGLFEPTDEQAAVIGAPPGPMVVI MLBr_00153|M.leprae_Br4923 ---------MSVHTTDAKPDSEVDRLLDGLNPQQRQAVVHEGSP--LLIV . :: *. : * .**.* . * :::: Mb3226c|M.bovis_AF2122/97 AGAGAGKTETMAARVVWLVANGYAEPGQVLGLTFTRKAAGQLLRRVRSRL Rv3201c|M.tuberculosis_H37Rv AGAGAGKTETMAARVVWLVANGYAEPGQVLGLTFTRKAAGQLLRRVRSRL MMAR_1359|M.marinum_M AGAGAGKTETMAARVVWLVANGYAEPGQVLGLTFTRKAAGQLLRRVRSRL MUL_2520|M.ulcerans_Agy99 AGAGAGKTETMAARVVWLVANGYAEPGQVLGLTFTRKAAGQLLRRVRSRL MAV_4147|M.avium_104 AGAGAGKTETMAARVVWLIANGYAHPGQVLGLTFTRKAAGQLLRRVRSRL Mflv_4665|M.gilvum_PYR-GCK AGAGAGKTETMAARVVWLVANGYATPGEVLGLTFTRKAAGQLLRRVRSRL Mvan_1802|M.vanbaalenii_PYR-1 AGAGAGKTETMAARVVWLVANGYARPGEVLGLTFTRKAAGQLLRRVRARL MSMEG_1943|M.smegmatis_MC2_155 AGAGAGKTETMAARVVWLVANGFATPSQVLGLTFTRKAAGQLLRRVRTRL TH_1441|M.thermoresistible__bu AGAGAGKTETMAARVVWLVANGYARPDQVLGLTFTRKAAGQLLRRVRSRL MAB_3515c|M.abscessus_ATCC_199 AGAGAGKTETMAARVVWLVANGYATPGQVLGLTFTRKAAAQLLRRVRSRL MLBr_00153|M.leprae_Br4923 AGAGSGKTTVLARRIAYLIAARSVGVSQILAITFTNKAAAEMRERVARLV ****:*** .:* *:.:*:* . .::*.:***.***.:: .** : Mb3226c|M.bovis_AF2122/97 ARLAGIGLGCG------DPAACAPVVSTYHAFAGSLLRDYGLLLPLEPDT Rv3201c|M.tuberculosis_H37Rv ARLAGIGLGCG------DPAACAPVVSTYHAFAGSLLRDYGLLLPLEPDT MMAR_1359|M.marinum_M ARLAGTTVGVAV-----GEAAGAPTVSTYHAFAGSLLRDHGLLLPIEPDT MUL_2520|M.ulcerans_Agy99 ARLAGTTVGVAV-----GEAAGAPTVSTYHAFAGSLLRDHGLLLPIEPDT MAV_4147|M.avium_104 ARLAGVGLGAASPNHGAVDPEAAPVVSTYHAFAGSLLRDYGLLLPVEPDT Mflv_4665|M.gilvum_PYR-GCK ARLAGAGLTIPAA--GADLADDPVTIGTYHAFAGTLLREFGLMLPVEPDT Mvan_1802|M.vanbaalenii_PYR-1 ARLAGAGLMIPTG--GADFADDPVTISTYHAFAGNLLREFGLLLPVEPDT MSMEG_1943|M.smegmatis_MC2_155 ARLAGAGLAP-----GSGASDESATVSTYHAFAGTLLREHGLLLPVEPDT TH_1441|M.thermoresistible__bu ARLAGTGLVPANS--APDWTTESVTVSTYHAFAGTLLREHGLLLPVEPDT MAB_3515c|M.abscessus_ATCC_199 ARLAGSGILAP-----VAADEPDPVIATYHAYAGTLLREHGLLLPMEPNA MLBr_00153|M.leprae_Br4923 GDHTGP----------------SMWVSTFHSTCVRILRNQASLIGGLNSN . :* :.*:*: . :**: . :: . Mb3226c|M.bovis_AF2122/97 RLLSETELWQLAFDVVSGYDGVLCTDKSPAAVTSIVVRLWGQLGEHLVDT Rv3201c|M.tuberculosis_H37Rv RLLSETELWQLAFDVVSGYDGVLCTDKSPAAVTSIVVRLWGQLGEHLVDT MMAR_1359|M.marinum_M RLLSETELWQLAFEVVNGYRGELCTQKTPAAVTATVLRLWGQLAEHLVDT MUL_2520|M.ulcerans_Agy99 RLLSETELWQLAFEVVNGYRGELCTQKTPAAVTATVLRLWGQLAEHLVDT MAV_4147|M.avium_104 RLLSETELWQLAFDVVNRYRGPLRTDKTPAAVTSMVLRLWGQLAEHLVDT Mflv_4665|M.gilvum_PYR-GCK RLLGETELWQLAFRVVCEHPAALDTDKSPASITAMVLRLAGQLSEHLVDT Mvan_1802|M.vanbaalenii_PYR-1 RLLGETELWQLAFRVVCAHPAALDTEKSPASITDMVLRLAGQLSEHLVDT MSMEG_1943|M.smegmatis_MC2_155 RLLSETELWQLAYDVVCAHPGHLDTEKTPAAVTAMVLRLSGALAEHLVDT TH_1441|M.thermoresistible__bu RLIGETELWQLAYRVVCEHPGPLDTDKTPAAITAMVLRLAGQLAEHLVDT MAB_3515c|M.abscessus_ATCC_199 RLLTETQLWQLAFRLVCDFDGDLDTEKTPGAVTAQVLALAGQLSEHLVNT MLBr_00153|M.leprae_Br4923 FSIYDVDDSRSLLQMIGQDMGLDIKRYSPRLMANAISNLKNELIDAESAV : :.: : :: . . :* :: : * . * : . Mb3226c|M.bovis_AF2122/97 RALRDTHVELERLVHALPAGRYQRDRGPSQWLLRMLATQTQRAELVPLLD Rv3201c|M.tuberculosis_H37Rv RALRDTHVELERLVHALPAGRYQRDRGPSQWLLRMLATQTQRAELVPLLD MMAR_1359|M.marinum_M RQLRDTHIELERLVHALPAGPNQRDSGPNQWLLRMLATQTERAELVPLLD MUL_2520|M.ulcerans_Agy99 RQLRDTHIELERLVHALPAGPNQRDSGPNQWLLRMLVTQTERAELVPLLD MAV_4147|M.avium_104 SQLRETHLELERLVHALPAGPYQRDRGPSQWLRRLSGTQSERAELVPLLE Mflv_4665|M.gilvum_PYR-GCK EQLRDTHVELDRLVHTLPAGRYQRDRGPSQWLLRMLATQTERTMLVPLID Mvan_1802|M.vanbaalenii_PYR-1 AALRDTHVELERLVLNLPAGRYQRDRGPSQWLLRMLATQTERTMLVPLVD MSMEG_1943|M.smegmatis_MC2_155 DQLRDTHVELERLVHTLPAGPYQRDRGPSQWLLRMLATQTERTELVPLID TH_1441|M.thermoresistible__bu DQLRDTHVELERLVHTLPAGPYQRDRGPSQWLLNMLATQTERAALVPLID MAB_3515c|M.abscessus_ATCC_199 TDLLSSHDELERLILTLPPGPRQREGGPSAWLLRLIETQRERTQLMAIVE MLBr_00153|M.leprae_Br4923 ANLSSDTDDLARTVATVYG------------------------------- * . :* * : : Mb3226c|M.bovis_AF2122/97 ALGERMHAGKVMDFAMQMASAARLAATSPQVGQDLRRRYRVVLLDEYQDT Rv3201c|M.tuberculosis_H37Rv ALGERMHAGKVMDFAMQMASAARLAATSPQVGQDLRRRYRVVLLDEYQDT MMAR_1359|M.marinum_M ALHERMRAAKVMDFGMQMAAAARLAATCPQVGEELRSRYRVVLLDEYQDT MUL_2520|M.ulcerans_Agy99 ALHERMRAAKVMDFGMQMAAAARLAATCPQVGGELRSRYRVVLLDEYQDT MAV_4147|M.avium_104 ALDERMRAVKVMDFGMQMASAARLAAAFPQVGADLRGRYRVVLLDEYQDT Mflv_4665|M.gilvum_PYR-GCK ALHRRMREERVMDFGMQMASAARLASTHPAVGEQLRQRYRVVLLDEYQDT Mvan_1802|M.vanbaalenii_PYR-1 ALHRRMREERVMDFGMQMASAARLAAQFPQVGAQLRQRYRVVLLDEYQDT MSMEG_1943|M.smegmatis_MC2_155 ALHQRMRAEKVMDFGMQMAAAARLAARFPQVGEQLRQRFRVVLLDEYQDT TH_1441|M.thermoresistible__bu AVHRRMRAEKVMDFGMQMAAAARLASEHPQVGAALRQRFRVVLLDEYQDT MAB_3515c|M.abscessus_ATCC_199 QLIALMRTRGVLDFGAQMALSARLAADHPIVGQTQRERYRVVLLDEYQDT MLBr_00153|M.leprae_Br4923 EYQRRLRTANALDFDDLIGETVGILQAFPQIAEHYRRRFRHVLVDEYQDT :: .:** :. :. : * :. * *:* **:****** Mb3226c|M.bovis_AF2122/97 GHAQRVVLSSLFGGGVDDG------LALTAVGDPIQSIYGWRGASATNLP Rv3201c|M.tuberculosis_H37Rv GHAQRVVLSSLFGGGVDDG------LALTAVGDPIQSIYGWRGASATNLP MMAR_1359|M.marinum_M GHSQRVALSALFGGGVDDG------LALTAVGDPIQSIYGWRGASATNLP MUL_2520|M.ulcerans_Agy99 GHSQRIALSALFGGGVDDG------LALTAVGDPIQSIYGWRGASATNLP MAV_4147|M.avium_104 GHAQRIALSALFGGGVDDG------LALTAVGDPIQSIYGWRGASATNLP Mflv_4665|M.gilvum_PYR-GCK GHAQRVALSSLFGGGADDG------LALTAVGDPIQSIYGWRGASATNLP Mvan_1802|M.vanbaalenii_PYR-1 GHAQRVALSSLFGGGADDG------LALTAVGDPIQSIYGWRGASATNLP MSMEG_1943|M.smegmatis_MC2_155 GHAQRIALSSLFGGGADDG------LALTAVGDPIQSIYGWRGASATNLP TH_1441|M.thermoresistible__bu GHAQRIALSALFGGGVDDD------LALTAVGDPIQSIYGWRGASATNLP MAB_3515c|M.abscessus_ATCC_199 GHAQRILLSSLFGRGVDPD------LALTAVGDPIQSIYGWRGASATNLP MLBr_00153|M.leprae_Br4923 NHAQYVLVRELVGHGARNSPDDMPPGELCVVGDADQSIYAFRGSTISNIE .*:* : : *.* *. . * .***. ****.:**:: :*: Mb3226c|M.bovis_AF2122/97 RFTTDFPLSDGTPAPVLELLTSWRNPPQALRVANGISAEARRRSVAVRAL Rv3201c|M.tuberculosis_H37Rv RFTTDFPLSDGTPAPVLELLTSWRNPPQALRVANGISAEARRRSVAVRAL MMAR_1359|M.marinum_M RFSTDFALSDGAPAPVLELRTSWRNPPRALHLANAISAEARRRSVAVHAL MUL_2520|M.ulcerans_Agy99 RFSTDFALSDGAPAPVLELRTSWRNPPRALHLANAISAEPRRRSVAVHAL MAV_4147|M.avium_104 RFTTDFPRSDGTPAPVLELRTSWRNPPRTLRVANAISAEARRRSVAVHAL Mflv_4665|M.gilvum_PYR-GCK RFTTDFPLSDGTPAPTLELRTSWRNPPEVLHLANAASVDARRRSVEVRSL Mvan_1802|M.vanbaalenii_PYR-1 RFTTDFPLSDGTPAPTLELRTSWRNPPEVLHLANEVSVDARRRSVAVRAL MSMEG_1943|M.smegmatis_MC2_155 RFTTDFPYSDGTPAPTLELRTSWRNPPSTLHVANAVSEEARRRSVAVRAL TH_1441|M.thermoresistible__bu RFATDFPHSDGSPAPTLELRTSWRNPPRTLHLANAISAEARRRSVAVRAL MAB_3515c|M.abscessus_ATCC_199 RFTTDFPLPDGSPAPTRELRTSWRNPPEALHLANSVSEEARRRSVAVRPL MLBr_00153|M.leprae_Br4923 DFERDYP-----DTTTILLEQNYRSTQNILSAANSVIARNFGR----RDK * *:. :.. * .:*.. * ** * : Mb3226c|M.bovis_AF2122/97 RPRPDAPPGAVRCALLPDVQA-EREWIADHLRMRYQRAEADGVKPPTAAV Rv3201c|M.tuberculosis_H37Rv RPRPDAPPGAVRCALLPDVQA-EREWIADHLRMRYQRAEADGVKPPTAAV MMAR_1359|M.marinum_M RSRPDAPAGTVRCALLADVQA-ERDWIADQLQGHYQRAAADGVSPPTAAV MUL_2520|M.ulcerans_Agy99 RSRPDAPAGTVRCALLADVQA-ERDWIADQLQGHYQRAAADGVSPPTAAV MAV_4147|M.avium_104 CPRPDAPPGTVRCALLPDMVA-EREWIADHIDAHYRRARADGVSPPTAAV Mflv_4665|M.gilvum_PYR-GCK QPRPNAEPGSVRAALLSDVEA-ERDWVADQVAHRWHGGLAASGTAPTAAV Mvan_1802|M.vanbaalenii_PYR-1 QPRPGAEPGSVRCALLSDVER-ERDWVADQIARRWHAGIEADGAAPTAAV MSMEG_1943|M.smegmatis_MC2_155 RPRPDAEPGTIRCALLNNVAA-ERDWVADHLARAYHGAIGRGEAAPTAAV TH_1441|M.thermoresistible__bu RPRPDAEPGTIRCALLDDVQS-EREWVAEQLAALYRHARDAGDTPPTAAV MAB_3515c|M.abscessus_ATCC_199 LPRPDAASGRIACALLGDIAA-EREWVATQLAAVYEQAHREGNRPPSSAV MLBr_00153|M.leprae_Br4923 RLWTDAGKGELIVGYVSDNEHDEAKFIADEIDALVGGGE---ITYDDVAV ..* * : . : : * .::* .: . ** Mb3226c|M.bovis_AF2122/97 LVRRNADAAAIADTLRARGIPAEVVGLAGLLSIPEVAEVVAMLRLVADPT Rv3201c|M.tuberculosis_H37Rv LVRRNADAAAIADTLRARGIPAEVVGLAGLLSIPEVAEVVAMLRLVADPT MMAR_1359|M.marinum_M LVRRNADAAPIADALVARGIPVEVVGLAGLLSIPEVADLVAMLRLVGDPT MUL_2520|M.ulcerans_Agy99 LVRRNADAAPIADALVARGIPVEVVGLAGLLSIPEVADLVAMLRLVGDPT MAV_4147|M.avium_104 LVRRNADAAPIADALRARGIPVEVVGLAGLLSVPEVAELVAMLRLVADPT Mflv_4665|M.gilvum_PYR-GCK LVRRNADAAPMADALSRRGVPVEVVGLAGLLAVPEVADVVAMLRVAVDPT Mvan_1802|M.vanbaalenii_PYR-1 LVRRNADAAPMADALTRRGVAVEVVGLAGLLAVPEVADVVAMLRLAADPT MSMEG_1943|M.smegmatis_MC2_155 LVRRNADAAPMAEALTARGVPVEVVGVAGLLAVPEVADLVAMLRLIADPT TH_1441|M.thermoresistible__bu LVRRNADAAPMAQALTARGVPVEVVGLAGLLAVPEVADVVAMLRLAADPT MAB_3515c|M.abscessus_ATCC_199 LVRRNSDAAPMAEALAAQGVPAEVVGLTGLLGLPEVADTVAMLRLVADPT MLBr_00153|M.leprae_Br4923 LYRANNLSRSLEEVFIPTGIPYKVVGGFCFYESKEIRDLIAYLRVLDNPG * * * : .: :.: *:. :*** : *: : :* **: :* Mb3226c|M.bovis_AF2122/97 AGAAAMRVLTGPRWRLGARDLAALWRRALTLSG-----ESPSTASPESIA Rv3201c|M.tuberculosis_H37Rv AGAAAMRVLTGPRWRLGARDLAALWRRALTLSG-----ESPSTASPESIA MMAR_1359|M.marinum_M AGAAAMRVLTGPRWRLGGSDVAALWRRAVALVGGP---QVGASASPGAVA MUL_2520|M.ulcerans_Agy99 AGAAAMRVLTGPRWRLGGSDVAALWRRAVALVGGP---QVGASVSPGAVA MAV_4147|M.avium_104 AGAAAMRVLTGPRWRLGARDLAALWQRARALGGAG---TAGGPATAEAIA Mflv_4665|M.gilvum_PYR-GCK AGAAAVRVLTGPRWRLGARDLTALWRRAVTLVDTGP-SASDAVSATAEIV Mvan_1802|M.vanbaalenii_PYR-1 AGAAAVRVLTGPRWRLGARDVAALWRRAVALVEPG--ASSDGESATAGIV MSMEG_1943|M.smegmatis_MC2_155 AGSAVMRILTGPRWRFGARDIAALWRRAVELDDRP-----KGELGTADIV TH_1441|M.thermoresistible__bu AGSAAVRILTGPRWRLGARDLTALWRRAVELGTVEPPGARPDTDGVEQIL MAB_3515c|M.abscessus_ATCC_199 AGPAALRVLTGPRWRLGAHDLVVLWRRATGFGRGG----------APAVG MLBr_00153|M.leprae_Br4923 DAVSMRRILNTPRRGIGDR-------------------------AEACVS . : *:*. ** :* : Mb3226c|M.bovis_AF2122/97 MAASA---DADNPCLADAISDPGSAEGYSVAGYGRIGALAGELSALRGRL Rv3201c|M.tuberculosis_H37Rv MAASA---DADNPCLADAISDPGSAEGYSVAGYGRIGALAGELSALRGRL MMAR_1359|M.marinum_M AAAGP---DTDTACLADAICDPGPADWYSSAGYERIGALAAELNALRGHL MUL_2520|M.ulcerans_Agy99 AAAGP---DTDTACLADAICDPGPADWYSSAGYERIGALAAELNALRGHL MAV_4147|M.avium_104 SAADPRNVEADAVCLADAIADPGPAEGYSAAGYARIAALAAELSALRAHL Mflv_4665|M.gilvum_PYR-GCK AKLEP---DADDACLADAVCDPGPAAAYSPTGYARIVALGRELTALRAHL Mvan_1802|M.vanbaalenii_PYR-1 AQLGP---DADAACLADAICDPGPATAYSEAGHARIVALGRELTGLRAHL MSMEG_1943|M.smegmatis_MC2_155 AQAAP---DADTACVADAICDPGDAERYSPAGYERIVALGRELTMLRAHL TH_1441|M.thermoresistible__bu AGIGP---DADEPCLADAICDPGDAAAYSEEGYRRITALAQELTALRAHL MAB_3515c|M.abscessus_ATCC_199 PDVGE---EADIPCLADAISDPGTPDEYSPEGWKRLTALRRELSALRARL MLBr_00153|M.leprae_Br4923 VYAEN---TGTSFADALQAVAEGKVPMLNTRSVKAIAGFVALLDDLRCRV . * * . . : .: * ** :: Mb3226c|M.bovis_AF2122/97 GHSLPDLVAEVRRVLGVDCEVRASAPVSGGWAGPEHLDAFADVVAGYAER Rv3201c|M.tuberculosis_H37Rv GHSLPDLVAEVRRVLGVDCEVRASAPVSGGWAGPEHLDAFADVVAGYAER MMAR_1359|M.marinum_M GHWLPDLVAEVRRVLGLDCDVRAAATASGAWAGAEHLDAFADVVADYAER MUL_2520|M.ulcerans_Agy99 GHWLPDLVAEVRRVLGLDCDVRAAATASGAWAGAEHLDAFADVVADYAER MAV_4147|M.avium_104 DHPLGDLVAEVRRVMDLDCEVRAAAAAG--WAGTEHLDAFADVVAGYAER Mflv_4665|M.gilvum_PYR-GCK SSPLPDLVAEIRRTLGIDAEVRAAQPISAGWSGTEHLDRFGDVVAEFASR Mvan_1802|M.vanbaalenii_PYR-1 QSPLPDLLAEVRRVLGIDTEVRAAQPVSAGWSGTEHLDAFGDVVADFAAR MSMEG_1943|M.smegmatis_MC2_155 GHPLPELVAEVRRVLGLDAEARAARPVAAGWAGTENLDRFSDLVSDFAGH TH_1441|M.thermoresistible__bu HHPLPDLIAEIRRILGVDAEARAGQPVAAGWAGTENLDAFADVVAEFAVR MAB_3515c|M.abscessus_ATCC_199 GMPLTDLIAEVQRVLALDVELVAGRRGE----GLDQLRAFTDVAAGFAES MLBr_00153|M.leprae_Br4923 DDDLGELVESVLERSGYLRELESS-TDPQELARLDNLNELVSFAHEFSTE * :*: .: . : :. ::* : ... :: Mb3226c|M.bovis_AF2122/97 -----ASARSSEASVAGLLAYLDVAEVVENGLPPAELTVACDRVQVLTVH Rv3201c|M.tuberculosis_H37Rv -----ASARSSEASVAGLLAYLDVAEVVENGLPPAELTVACDRVQVLTVH MMAR_1359|M.marinum_M AAISAGSALSTKASVDGLLAYLDVAAEVENGLPPAQLTVARDRVQVLTVH MUL_2520|M.ulcerans_Agy99 TAISAGSALSTKASVDGLLAYLDVAAEVENGLPPAQLTVARDGVQVLTVH MAV_4147|M.avium_104 ADTG-GTDASASASVAGLLAFLDVAESVENGLPAAPLAVARDRVQVLTVH Mflv_4665|M.gilvum_PYR-GCK ----------GTPTASGLLAYLDTAEQVENGLAPAEVTVSSDRVQILTVH Mvan_1802|M.vanbaalenii_PYR-1 ----------GGATVSALLGYLDIAEQVENGLAPAEVTVSADRVQILTVH MSMEG_1943|M.smegmatis_MC2_155 ----------AGASVSALLAYLDAAVEVENGLAPAELTVSHDRVQILTVH TH_1441|M.thermoresistible__bu ----------PNATVPALLGYLSAAMEVENGLAPADVTVATDRVQILTVH MAB_3515c|M.abscessus_ATCC_199 -----ADQSDPVGVVSAFLQYLDAAWEIEKGLAPVEVAASPGRVQILTVH MLBr_00153|M.leprae_Br4923 -----------QANAAALAKSLHTPEDED--------------------- . .: * . : Mb3226c|M.bovis_AF2122/97 AAKGLEWQVVAVAHLSRGVFPSTVSRSSWLTDPAELPPLLRGDRASAG-A Rv3201c|M.tuberculosis_H37Rv AAKGLEWQVVAVAHLSRGVFPSTVSRSSWLTDPAELPPLLRGDRASAG-A MMAR_1359|M.marinum_M AAKGLEWQVVAVAHLSAGVFPSTASRSSWLTDPGELPPLLRGDRASVG-A MUL_2520|M.ulcerans_Agy99 AAKGLEWQVVAVAHLSAGVFPSTASRSSWLTDPGELPPLLRGDRASVG-A MAV_4147|M.avium_104 SAKGLEWQLVAVAHLSGGVFPSTTAKTTWLTDAAELPPLLRGDRARPG-A Mflv_4665|M.gilvum_PYR-GCK AAKGLEWQIVAVPHLVGRVFPSTASPRTWLTDAADLPPLLRGDCATVS-A Mvan_1802|M.vanbaalenii_PYR-1 AAKGLEWQIVAVPHLSGRVFPSTASPRTWLTDAADLPPLLRGDCATVS-E MSMEG_1943|M.smegmatis_MC2_155 AAKGLEWQVVAVPHLSARVFPSTTQARTWLTDASDLPPLLRGDRATES-E TH_1441|M.thermoresistible__bu AAKGLEWEVVAVPHLSRRVFPSTASPRTWLTDAGELPPLLRGDRATTS-E MAB_3515c|M.abscessus_ATCC_199 SAKGLEWDVVAVPHLSAGVFPSGVAAPTWLTSATELPPLVRGDRASQGDQ MLBr_00153|M.leprae_Br4923 -------------VPDTGALAAFLEKVSLMSDTDQIPENNSGVVTLMT-L .:.: : ::.. ::* * : Mb3226c|M.bovis_AF2122/97 HGIPVLDTSAVADRKQLSDKISEHRRLLDRRRVDEERRLLYVAVTRAEDT Rv3201c|M.tuberculosis_H37Rv HGIPVLDTSAVADRKQLSDKISEHRRLLDRRRVDEERRLLYVAVTRAEDT MMAR_1359|M.marinum_M LGIPVLDTSAVTNRKQLSDTISAHREQLDQRRVDEERRLLYVGVTRAEDT MUL_2520|M.ulcerans_Agy99 LGIPVLDTSAVTNRKQLSDTISAHREQLDQRRVDEERRLLYVGVTRAEDT MAV_4147|M.avium_104 LGIPVLDTSDVTNRKQLSDKISEHRRQLEQRRVDEERRLLYVAVTRAEDT Mflv_4665|M.gilvum_PYR-GCK HGVPVLDTSDVSDRKGLSDKIAAHKSSLDQRRTDEERRLLYVAITRAEHT Mvan_1802|M.vanbaalenii_PYR-1 HGVPVLDTSDVSDRKGLSDKIYDHKRSLEQRRTDEERRLLYVAITRAEHT MSMEG_1943|M.smegmatis_MC2_155 IGVPVLDTSDIYDRKILSDKISDHKKSLDQRRVDEERRLLYVAITRAEDT TH_1441|M.thermoresistible__bu HGVPVLDTADVNDRKALSDKIAEHKNRLAQRRTDEERRLLYVAVTRAEDT MAB_3515c|M.abscessus_ATCC_199 FGVPQLDTEGITNRKQLADAIARHKDSLATRRIDEERRLLYVAVTRCAEQ MLBr_00153|M.leprae_Br4923 HAAKGLEFPVVFVTGWEDGMLPHMRTLGDPTELSEERRLAYVGITRARQR . *: : . : : . .***** **.:**. . Mb3226c|M.bovis_AF2122/97 LLVSGHHWGPTGTKPRGPSEFLCELKDIIDRSAAAGDPCGVVEQWASAPA Rv3201c|M.tuberculosis_H37Rv LLVSGHHWGPTGTKPRGPSEFLCELKDIIDRSAAAGDPCGVVEQWASAPA MMAR_1359|M.marinum_M VLVSGHHWGATGLKPRGPSDFLCELKDIIERSAAAGDPCGTVDQWDPAPV MUL_2520|M.ulcerans_Agy99 VLVSGHHWGATGLKPRGPSDFLCELKDIIERSAAAGDPCGTVDQWDRAPV MAV_4147|M.avium_104 LLVSGHHWAATGIKPRGPSDFLCEIKDVIDASAAAGDPCGTVEQWAPAPA Mflv_4665|M.gilvum_PYR-GCK LLVSGHHWGATESKPRGPSTFLTEIKDVIDASIEEGRPCGSIAVWADAPA Mvan_1802|M.vanbaalenii_PYR-1 LLVSGHHWGATESKPRGPSTFLCELKDVIDASVQSGSPCGAVDVWADAPA MSMEG_1943|M.smegmatis_MC2_155 LLLSGHHWGATESKPRGPSEFLCELKTILEEATAAGTPCGEIEHWAPDPA TH_1441|M.thermoresistible__bu LLVSGHHWGATESKPRGPSEFLLEIKDVIDRSAEAGDPCGTIDLWAPEPP MAB_3515c|M.abscessus_ATCC_199 LFVSGHHWGQTGLKPKGPSDFLVELRDVIESAAAEGVPCGTVERWAPEPP MLBr_00153|M.leprae_Br4923 LYLS---------------------------------RAITRSSWGQPIL : :* . * Mb3226c|M.bovis_AF2122/97 GDERNPLCDNAIEAVWPADPLAARRGDVERGAALVAAAMSADLPGSTTDI Rv3201c|M.tuberculosis_H37Rv GDERNPLCDNAIEAVWPADPLAARRGDVERGAALVAAAMSADLPGSTTDI MMAR_1359|M.marinum_M AGERNPLLDDVVEAVWPTDPLATRRGDVERGARLVAEAISADA-GVEAPA MUL_2520|M.ulcerans_Agy99 AGERNPLLDDVVEAVWPTDPLATRRGDVERGARLVAEAISADA-GVEAPA MAV_4147|M.avium_104 DGERNPLRDNAVEAVWPADPLASRRGEVERGAALVRQAMAAEP------- Mflv_4665|M.gilvum_PYR-GCK DGETNPIRDRVVEAVWPVDPVAGRRGPVDRGAHLVAEALSGECPEV---- Mvan_1802|M.vanbaalenii_PYR-1 DGEPNPLRDRVVEAVWPEDPLAGRRAHTDHGARLVTTAMSTAGGAG---- MSMEG_1943|M.smegmatis_MC2_155 PGETNPLRDQVVEALWP--PVASADDHVHRGAQLVAAAMAGEVSA----- TH_1441|M.thermoresistible__bu DGTPNPLRDKAFEVLWPAPPXXXPAGPPPPVSPRITTPSAGGA------- MAB_3515c|M.abscessus_ATCC_199 AGERNPMLDQTVEAQWPADPLAGRRDDIEAGARLVRAALADGAALTME-- MLBr_00153|M.leprae_Br4923 NPESRFLR------EIPPELIDWRR------------------------- . : * Mb3226c|M.bovis_AF2122/97 DHPPRPGDAPWSTDVDALLAERAHAARGAPARGLPNHLSVSSLVELVGDP Rv3201c|M.tuberculosis_H37Rv DHPPRPGDAPWSTDVDALLAERAHAARGAPARGLPNHLSVSSLVELVGDP MMAR_1359|M.marinum_M GGAAVADIEGWTADVDALLAERARAVG-PPTRALPNQLSVSGLVELARDP MUL_2520|M.ulcerans_Agy99 GGAAVADIEGWTADVDALLAERARAVG-PPTRALPNQLSVSGLVELARDP MAV_4147|M.avium_104 -GDPGADVEGWAADVDALLVERARVTG-PPPQVLPGQLSVSSLVGLARDP Mflv_4665|M.gilvum_PYR-GCK ---GSDDDHGWVADVDALLAERDLAAQ-RAVPSLPAQLSVSAMVELGRDP Mvan_1802|M.vanbaalenii_PYR-1 ---PQPDVHGWTADVDALLAERELAAQ-RPVPPLPLQLSVSAMVELGRDP MSMEG_1943|M.smegmatis_MC2_155 ----EADQEGWAADVDALLAERERPPQ-QEDTELPGQLSVSTLVELSRDP TH_1441|M.thermoresistible__bu ----QPNRRRLIAGVAGVAA-----------VAVLGGLAFWLLSPSGTDQ MAB_3515c|M.abscessus_ATCC_199 ---DDDDTDGWEADVDALLREREQGHR-RPEMTLPQHLSVTSLVELRQDP MLBr_00153|M.leprae_Br4923 ----------------------------------------SILTDSYSTP : Mb3226c|M.bovis_AF2122/97 VGARQRLMCRLPKRPDPHAWLGDAFHAWVQQFYGAELLFDLGDLPGAADR Rv3201c|M.tuberculosis_H37Rv VGARQRLMCRLPKRPDPHAWLGDAFHAWVQQFYGAELLFDLGDLPGAADR MMAR_1359|M.marinum_M VGARQRLVHRLPTRPDPHAQLGNAFHTWVQQFYGAELLFDLGDLPGAADS MUL_2520|M.ulcerans_Agy99 VGARQRLVHRLPTRPDPHAQLGNIFHTWVQQFYGAELLFDLGDLPGAADS MAV_4147|M.avium_104 ARAAQRLRHRLPSRPEPHALLGNAFHAWVQKFYGAECLFELGDLPGAADS Mflv_4665|M.gilvum_PYR-GCK EAVAHRLQRRLPRRPDSHALLGTAFHEWVQRYFQAEKLFDLDDLPGAVDA Mvan_1802|M.vanbaalenii_PYR-1 EAVAQRLQRRLPRRPDAQALLGTAFHEWVQRYFQAEKLFDLDDLPGAVDA MSMEG_1943|M.smegmatis_MC2_155 KAALTRLRRRLPQRPDPHALLGTTFHEWVQRYFHAERLFDLDDLPGAVDS TH_1441|M.thermoresistible__bu ADGARADDTAETTSPPRDTAAENRLLTMLPPGYSAGACGPVPAPEGALAQ MAB_3515c|M.abscessus_ATCC_199 QALARRLARPRPTRPDLDARRGTAFHSWVQRHYGSVRLIDFEDLPGDGYG MLBr_00153|M.leprae_Br4923 ASGASRFGRVRPSSIRSG-------------------------------- . Mb3226c|M.bovis_AF2122/97 E--VGDPEELAALQRAFTASSWAARTPAAVEVPFEMPIGDTVVRGRIDAV Rv3201c|M.tuberculosis_H37Rv E--VGDPEELAALQRAFTASSWAARTPAAVEVPFEMPIGDTVVRGRIDAV MMAR_1359|M.marinum_M D--VGQVEDLAPLQEAFAGSPWAARTPIAVEVPFEMPVGDTVVRGRIDAV MUL_2520|M.ulcerans_Agy99 D--VGQVEDLAPLQEAFAGSPWAARTPIAVEVPFEMPVGDTVVRGRIDAV MAV_4147|M.avium_104 D--VGDTAELAELQAAFLESPWAARTPVAVEVPFEMPIGDTLVRGRIDAV Mflv_4665|M.gilvum_PYR-GCK D--RQDRGELDELQTAFAVSPWAARTPIDVEVPFDMMLAGRIVRGRIDAI Mvan_1802|M.vanbaalenii_PYR-1 D--RQDRGELEELQAAFALSPWAARTPIDVEVPFDMMIAGRVVRGRIDAV MSMEG_1943|M.smegmatis_MC2_155 DSGRAVEESLAELQDAFVKSPWAARTPVEVEVPFDMVLGETVVRGRIDAV TH_1441|M.thermoresistible__bu VVCRENTDPGGPPTATYT----LARDEAAMQRAFDEIIAASATVN--CPN MAB_3515c|M.abscessus_ATCC_199 S--FEDAEDLAALQSAFLESEWADRTPVEVEVPFEISVAGIVVRGRIDAV MLBr_00153|M.leprae_Br4923 ----------------------ASKRALLVLAPGDRVTHDKYGLGRVEEV : : . : . Mb3226c|M.bovis_AF2122/97 FV--DPDGGATVVDWKTGKPPHGPAAMRQAAVQLAVYRLAWAALRGCPTS Rv3201c|M.tuberculosis_H37Rv FV--DPDGGATVVDWKTGKPPHGPAAMRQAAVQLAVYRLAWAALRGCPTS MMAR_1359|M.marinum_M FE--DPDGGATVVDWKTGEPPRGPEAMRQAAVQLAVYRMAWAALRGCPES MUL_2520|M.ulcerans_Agy99 FE--DPDGGATVVDWKTGEPPRGPEAMRQAAVQLAVYRMAWAALRGCPES MAV_4147|M.avium_104 FA--ESDGGATVVDWKTGAPPDSPEAMRQAAVQLAVYRLAWAALAKVPES Mflv_4665|M.gilvum_PYR-GCK FA--DGDGSFTVVDWKTGEMPTDPEVLAHNALQLAVYRLAWARLHGCPTS Mvan_1802|M.vanbaalenii_PYR-1 FA--DGDG-VMVVDWKTGEPPATEEELQHNAVQLAVYRLAWARLHDCPVS MSMEG_1943|M.smegmatis_MC2_155 FA--EPDGTTMVLDWKTGDPPETPEAKEHAAVQLAVYRLAWAAMRGCPPE TH_1441|M.thermoresistible__bu FI--QSPG-----PWRRNATPDRISGTLFCGIQQNEPLVAWTDDANLVVS MAB_3515c|M.abscessus_ATCC_199 FGPDSAEDTWTVVDWKTGHEPAG-DEMKAAALQLAVYRRAWASLREIDPA MLBr_00153|M.leprae_Br4923 SG--VGESAISLIDFGSS-----------GRIKLMHNHAPVTKL------ . : . :: . : Mb3226c|M.bovis_AF2122/97 SVRTAFYYVRSGITVVPDELPAPGELAMLLTDCAGRRSDT----- Rv3201c|M.tuberculosis_H37Rv SVRTAFYYVRSGITVVPDELPAPGELAMLLTDCAGRRSDT----- MMAR_1359|M.marinum_M SVRTAFHYVRTGVTVIPDELPDGMALAELLADSDPPCSC------ MUL_2520|M.ulcerans_Agy99 SVRTAFHYVRTGVTVIPDELPDGMALAELLADSDPPCSC------ MAV_4147|M.avium_104 SVRTAFHYVRARTTVVPEALPTSDQLAGLLAPTAPV--------- Mflv_4665|M.gilvum_PYR-GCK AVRAAFHYVRSGRTVMPDALPEEDDLIALLADRDDEDAA------ Mvan_1802|M.vanbaalenii_PYR-1 SVRAAFHYVRSGRTVVPDGLPDADDLAALLADPPAA--------- MSMEG_1943|M.smegmatis_MC2_155 SVRAAFHYVRSGQTVIPETLPGAEELVKLLAAAPTETAEEADRIT TH_1441|M.thermoresistible__bu AVHSG---------------PQGPTLDELYAWWTTHS-------- MAB_3515c|M.abscessus_ATCC_199 RVRAVFHYVRSGRTVAPTELPDLPHAEELAELTRD---------- MLBr_00153|M.leprae_Br4923 ---------------------------------------------