For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMPSLPWPAAD DWLAAVRASPLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQPRTEVPTYERLFPQGFEEQRA AADIALSQGLTVLTGGPGTGKTTTVARLLALLADQASSASAAPLRIALAAPTGKAAARLQEAVQLEVNQL DAVDRSRLAGLQATTLHRLLGSRPDTSSRFKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLL LVGDPDQLASVEAGAVLADLVEGLESERVAALRTSHRFGAAIGALAAAVRDGDADRALEVLASGDPHVEW STDSEGLRDVLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGVTHWNRQVERWITEETGEPHW APWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMTIHKSQGSQANE VTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRASGLGRRLRHSPN*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0398c | - | - | 100% (552) | exodeoxyribonuclease V, alpha subunit (RecD) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0645c | recD | 0.0 | 67.62% (559) | exonuclease V alpha chain |
M. gilvum PYR-GCK | Mflv_5131 | - | 0.0 | 70.24% (551) | exodeoxyribonuclease V, alpha subunit |
M. tuberculosis H37Rv | Rv0629c | recD | 0.0 | 67.80% (559) | exonuclease V alpha chain |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | MMAR_0956 | recD | 0.0 | 69.34% (561) | exodeoxyribonuclease V (alpha chain), RecD |
M. avium 104 | MAV_4544 | recD | 0.0 | 74.55% (550) | exodeoxyribonuclease V, alpha subunit |
M. smegmatis MC2 155 | MSMEG_1325 | recD | 0.0 | 77.68% (551) | exodeoxyribonuclease V, alpha subunit |
M. thermoresistible (build 8) | TH_1237 | - | 8e-05 | 29.24% (171) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_0707 | recD | 0.0 | 69.52% (561) | exodeoxyribonuclease V (alpha chain), RecD |
M. vanbaalenii PYR-1 | Mvan_1208 | - | 0.0 | 73.14% (551) | exodeoxyribonuclease V, alpha subunit |
CLUSTAL 2.0.9 multiple sequence alignment Mb0645c|M.bovis_AF2122/97 -------MKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGES Rv0629c|M.tuberculosis_H37Rv -------MKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGES MAB_0398c|M.abscessus_ATCC_199 -------------------MSLVEAF--GEILEPADVHVAQRLTALASET MSMEG_1325|M.smegmatis_MC2_155 -------------------MSLLEAF--AEILEPADVHVAQRLTVLADEP Mflv_5131|M.gilvum_PYR-GCK --------------------MSLDAF--AEVFEPADIHVAQRLTELGRDS Mvan_1208|M.vanbaalenii_PYR-1 --------------------MTVEAF--SELFEPADLHVAQRLTTLGKEG MMAR_0956|M.marinum_M --MTIDVVDPADWRQAASASGPLRTFNEAGVIDAADVHVAQRLAAMSGES MUL_0707|M.ulcerans_Agy99 --MTIEVVDPADWRQAASASGPLRTFNEARVIDAADVHVAQRLAAMSGES MAV_4544|M.avium_104 -----------MLPERVFDAGPLRPFADAGIFEAADIHVAQRLTALTGES TH_1237|M.thermoresistible__bu VPAELRSAHPDIPGVPWWGAALIALTATALGFAFDAGSGSKELSVVFSGT : . : ::.* : Mb0645c|M.bovis_AF2122/97 DERVALAVAVAVRALRA----------------GSVCVDLLSIARVAGHD Rv0629c|M.tuberculosis_H37Rv DERVALAVAVAVRALRA----------------GSVCVDLLSIARVAGHD MAB_0398c|M.abscessus_ATCC_199 DESVELAIALAVRALRG----------------GSVCVDLRAVAAQVDMP MSMEG_1325|M.smegmatis_MC2_155 DASVELAVALAVRALRG----------------GSVCVDLRSVAGQVELP Mflv_5131|M.gilvum_PYR-GCK DPTVALAVALAVRAVRS----------------GSVCVDLRTVAAQVGVP Mvan_1208|M.vanbaalenii_PYR-1 DDSVALAVALAVRALRG----------------GSVCVDLRAIATQVGMP MMAR_0956|M.marinum_M DPVVLLAIAFVVRALRG----------------GSVCVDLSTIEAQVGIA MUL_0707|M.ulcerans_Agy99 DPVVLLAIAFVVRALRG----------------GSVCVDLSTIEAQVGIA MAV_4544|M.avium_104 DDRVALAVALLVRALRG----------------GSVCVDLRAVPAQVGAA TH_1237|M.thermoresistible__bu YMLGCLVAVLAVRPGRPPIVLFAAVPSAYFLFHGGQIRGLKDLAINCGYP *. .. **. * *. .* : Mb0645c|M.bovis_AF2122/97 DLP-WPDPA-DWLAAVRASP-LLADPPVLHLYDDRLLYLDRYWREEEQVC Rv0629c|M.tuberculosis_H37Rv DLP-WPDPA-DWLAAVRASP-LLADPPVLHLYDDRLLYLDRYWREEEQVC MAB_0398c|M.abscessus_ATCC_199 SLP-WPAAD-DWLAAVRASP-LAGEPPVLRLFGD-LLYLDRYWREEQQVC MSMEG_1325|M.smegmatis_MC2_155 DLP-WPDPD-AWLAALAASP-LLGQPPVLRLFGD-LLYLDRYWLEEQQVC Mflv_5131|M.gilvum_PYR-GCK ELP-WPDPD-GWLSTVGASP-LAEHK-VVRLDGD-LLYLDRYWREEEQVR Mvan_1208|M.vanbaalenii_PYR-1 ELP-WPEPD-RWLAAVGASP-LADER-VLRMHGD-LLYLDRYWREEQQVC MMAR_0956|M.marinum_M DLP-WPAAG-EWLAAVRASP-LVGSPAVLRLHEDNLVYLDRYWREEQQVA MUL_0707|M.ulcerans_Agy99 DLP-WPAAG-EWLAAVRASP-LVGSPAVLRLHEDNLVYLDRYWREEQQVA MAV_4544|M.avium_104 DLP-WPAAG-DWLAAVRASP-LLGPPPVLRFFGD-LLYFDRYWLEEEQVC TH_1237|M.thermoresistible__bu LIERFPVXXXPFYTATAANPEGMRRRRQFHSRGRQLTGFTDEILGRPDAG : :* : :: *.* .: * : . :. Mb0645c|M.bovis_AF2122/97 ADLLALLTS--RRPAGVPDLR--RLFPTGFDEQRRAAEIALSQGVTVLTG Rv0629c|M.tuberculosis_H37Rv ADLLALLTS--RRPAGVPDLR--RLFPTGFDEQRRAAEIALSQGVTVLTG MAB_0398c|M.abscessus_ATCC_199 TDVQALMAA-AQPRTEVPTYE--RLFPQGFEEQRAAADIALSQGLTVLTG MSMEG_1325|M.smegmatis_MC2_155 DDVLALVS--ARPGGAVPDVS--RLFGAGFEEQRAAAKVALSQGLTVLTG Mflv_5131|M.gilvum_PYR-GCK DDVVALLS--SPPRTAVPGLE--RLFPAGWEEQRAAAEAALTRSLTVLTG Mvan_1208|M.vanbaalenii_PYR-1 DDVLALLA--SPLPATAPSIE--RLFPAGWEEQREAAKVALRQSLTVLTG MMAR_0956|M.marinum_M DDILALLAARASASGPAIEVN--RLFPPGYEEQRAAAKIALAQGLTVLTG MUL_0707|M.ulcerans_Agy99 DDILALLAARASASGPAIEVN--RLFPPGYEEQRAAAKIALAQGLTVLTG MAV_4544|M.avium_104 TDLLALSAP--AGDVESSCYE--RLFPPGYEEQRAAARIAVSQALTVLTG TH_1237|M.thermoresistible__bu EDLTGDPDAALLAAINAPRGPGMRDIVATIQAEQDAVIRLDHPGVLVIEG *: . * : : :: *. .: *: * Mb0645c|M.bovis_AF2122/97 GPGTGKTTTVAR--LLALVAEQAELAGE----PRPRIALAAPTGKAAARL Rv0629c|M.tuberculosis_H37Rv GPGTGKTTTVAR--LLALVAEQAELAGE----PRPRIALAAPTGKAAARL MAB_0398c|M.abscessus_ATCC_199 GPGTGKTTTVAR--LLALLADQASSASA----APLRIALAAPTGKAAARL MSMEG_1325|M.smegmatis_MC2_155 GPGTGKTTTVAR--LLALLAEQAALAGK----PSPRIALAAPTGKAAARL Mflv_5131|M.gilvum_PYR-GCK GPGTGKTTTVAR--LLAAFAEQAELAGG----PPPRMALAAPTGKAAARL Mvan_1208|M.vanbaalenii_PYR-1 GPGTGKTTTVAR--LLASIAEQAESAGG----APPRMALAAPTGKAAARL MMAR_0956|M.marinum_M GPGTGKTTTVAR--LLALFAEQAQLAGK----ARLRIALAAPTGKAAARL MUL_0707|M.ulcerans_Agy99 GPGTGKTTTVAR--LLALFAEQAQLAGK----ARLRIALAAPTGKAAARL MAV_4544|M.avium_104 GPGTGKTTTVAR--LLALLVEQAERAGE----PRPRIALAAPTGKAAARL TH_1237|M.thermoresistible__bu GPGTGKTAVALHRVAYLLYTRRSQLSGSGVLVVGPNPTFLDHIGRVLPNL *******:.. : . :: :. . :: *:. ..* Mb0645c|M.bovis_AF2122/97 AEAVRREMAKLDATDRARLGDLHAVTLHRLLG-------AKP--GARFRQ Rv0629c|M.tuberculosis_H37Rv AEAVRREMAKLDATDRARLGDLHAVTLHRLLG-------AKP--GARFRQ MAB_0398c|M.abscessus_ATCC_199 QEAVQLEVNQLDAVDRSRLAGLQATTLHRLLG-------SRPDTSSRFKH MSMEG_1325|M.smegmatis_MC2_155 QEAVQLEIDQLDLIERRRLTGLHATTLHRLLG-------PRPDTSSRFRH Mflv_5131|M.gilvum_PYR-GCK QDAVQAEVDRLSAVDRARLAGLRATTMHRLLG-------SRPDTSSRFRH Mvan_1208|M.vanbaalenii_PYR-1 QDAVHAEVGKLPAVDQGRLAGLRATTLHRLLG-------SRPDTSSRFRH MMAR_0956|M.marinum_M HEAVQSQIDKLDAIDQQRVRGLQATTLHRLLG-------SRPDTSSRFRH MUL_0707|M.ulcerans_Agy99 HEAVQSQIDKLDAIDQQRVRGLQATTLHRLLG-------SRPDTSSRFRH MAV_4544|M.avium_104 AEAVAAEIEHLDPADRARLAGLTGTTLHRLLG-------PRPDTSVRFKH TH_1237|M.thermoresistible__bu GESDVVFMTPGDLVPGLRVTAQDSDDAARVKGSLEILDVLRAAVADRQRL :: : *: . *: * :. . * : Mb0645c|M.bovis_AF2122/97 ---------------------------DRQNRLPHNVIVVDETSMVSLTL Rv0629c|M.tuberculosis_H37Rv ---------------------------DRQNRLPHNVIVVDETSMVSLTL MAB_0398c|M.abscessus_ATCC_199 ---------------------------DRGNRLPHDVIVVDETSMVSLTM MSMEG_1325|M.smegmatis_MC2_155 ---------------------------HRANRLPHDVIVVDETSMVSLTM Mflv_5131|M.gilvum_PYR-GCK ---------------------------HRGNRLPHDVIVVDETSMVSLTM Mvan_1208|M.vanbaalenii_PYR-1 ---------------------------HRDNRLPHDVIVVDETSMVSLTM MMAR_0956|M.marinum_M ---------------------------HRGNRLPHDVIVIDETSMVSLTM MUL_0707|M.ulcerans_Agy99 ---------------------------HRGNRLPHDVIVIDETSMVSLTM MAV_4544|M.avium_104 ---------------------------NRGNRLPHDIIVVDETSMVSLTM TH_1237|M.thermoresistible__bu PEEPLPIELSDVTVRIDAETAQWARQEARDSGLPHNEARAVFADVVTWVL * . ***: :.:*: .: Mb0645c|M.bovis_AF2122/97 MARLAEAV------RPGARLILVGDADQLASVEAGAVLADLVDGFSVRDD Rv0629c|M.tuberculosis_H37Rv MARLAEAV------RPGARLILVGDADQLASVEAGAVLADLVDGFSVRDD MAB_0398c|M.abscessus_ATCC_199 MARLLEAV------RPQARLLLVGDPDQLASVEAGAVLADLVEGLES--- MSMEG_1325|M.smegmatis_MC2_155 MARLLEAV------RPQTRLVLVGDPDQLASVEAGAVLADLVEGLGS--- Mflv_5131|M.gilvum_PYR-GCK MARLLEAV------RPDTRLLFVGDPDQLASVDAGAVLADLVDGLGE--- Mvan_1208|M.vanbaalenii_PYR-1 MARLLEAV------RPDTRLLFVGDPDQLASVDAGAVLADLVEGLGD--- MMAR_0956|M.marinum_M MARLLEAV------RPQTRLLLVGDPDQLASVEAGAVLADLVDGLGARHD MUL_0707|M.ulcerans_Agy99 MARLLEAV------RPQTRLLLVGDPDQLASVEAGAVLADLVDGLGARHD MAV_4544|M.avium_104 MARLAEAV------RPDTRLILVGDPDQLASVEAGAVLADLVDGLAGRAG TH_1237|M.thermoresistible__bu TERAIARIGRGWLTRDDRAAWEELRADLLDELANNADYAAALDQLWPILT * : * .* * .: .* * :: : Mb0645c|M.bovis_AF2122/97 --ALVAQLRTSHRFGKVIGTLAEAIRAGDGDAVLGLLRSGEERIEFVDDE Rv0629c|M.tuberculosis_H37Rv --ALVAQLRTSHRFGKVIGTLAEAIRAGDGDAVLGLLRSGEERIEFVDDE MAB_0398c|M.abscessus_ATCC_199 --ERVAALRTSHRFGAAIGALAAAVRDGDADRALEVLASGDPHVEWS-TD MSMEG_1325|M.smegmatis_MC2_155 --RGVAELKTSHRFGESIGALASAIRTGDADAALAVLAAGGEHIEWV-HE Mflv_5131|M.gilvum_PYR-GCK --AGVVELTTSHRFGERIGALALAIRSGDADATVEVLRAGGDAIGWLDTD Mvan_1208|M.vanbaalenii_PYR-1 --AGVVELKTPHRFGETIGSLAEAIRAGDADTAVQLLRAGGDAVAWLDTD MMAR_0956|M.marinum_M --THVAALRRLHRFGESIGQLAAAIRGGDADRVVEILRAGDDHIEWINAA MUL_0707|M.ulcerans_Agy99 --THVAALRRLHRFGESIGQLAAAIRGGDADRVVEILRAGDDHIEWINAA MAV_4544|M.avium_104 --VRVAALATPHRFGSAIGALAAAIRAGDADRVVELLAAGGEHIEWVDSE TH_1237|M.thermoresistible__bu PQQLLADLYTSPERLRAVGADPALYRADGEAWTVSDVPLLDELIDLLGPD :. * . :* . * .. .: : : Mb0645c|M.bovis_AF2122/97 DPAPRLRAVLVPHALRLREAALLGASDVALATLDEHRLL----------- Rv0629c|M.tuberculosis_H37Rv DPAPRLRAVLVPHALRLREAALLGASDVALATLDEHRLL----------- MAB_0398c|M.abscessus_ATCC_199 S--EGLRDVLVPQALALRAASLSGDATAALAVLDEHRML----------- MSMEG_1325|M.smegmatis_MC2_155 DPVEQLREVVVPHAMRLRQAAILGDQREALATLDEHRLL----------- Mflv_5131|M.gilvum_PYR-GCK DAADALRGPLVDRAADLREAALLGDGETALRILDGHRLL----------- Mvan_1208|M.vanbaalenii_PYR-1 DPSDALRATLVARADELRRAALLGDARAALGVLDGHRLL----------- MMAR_0956|M.marinum_M DPTPQLRNVLLPHALELRRAGALGDTAAALATLDEQRLL----------- MUL_0707|M.ulcerans_Agy99 DPTPQLRNVLLPHALELRRAGALGDTAAALATLDEQRLL----------- MAV_4544|M.avium_104 RPADRLREVLVSHALRLRSAALLGAAQAALATLDEHRLL----------- TH_1237|M.thermoresistible__bu KPADDTAERERQKQAEYAAEVLESLVRREDLMDDEDRLLPTDMLFGEDLA : . * .*:* Mb0645c|M.bovis_AF2122/97 -------------------------------------------------- Rv0629c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_5131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_0956|M.marinum_M -------------------------------------------------- MUL_0707|M.ulcerans_Agy99 -------------------------------------------------- MAV_4544|M.avium_104 -------------------------------------------------- TH_1237|M.thermoresistible__bu ERFAERDHRDLAERAAADRDWVYGHIVVDEAQELSEMDWRALMRRCPSRS Mb0645c|M.bovis_AF2122/97 ------CAHRDGPTGVLHWNRRVQAWLAEETGQPPWTPWYAGRPLLVTAN Rv0629c|M.tuberculosis_H37Rv ------CAHRDGPTGVLHWNRRVQAWLAEETGQPPWTPWYAGRPLLVTAN MAB_0398c|M.abscessus_ATCC_199 ------CAHRHGPFGVTHWNRQVERWITEETGEPHWAPWYAGRPILVTAN MSMEG_1325|M.smegmatis_MC2_155 ------CAHRRGPAGVDHWNRQVQRWLGEETGEPLWGSWYVGRPILVTAN Mflv_5131|M.gilvum_PYR-GCK ------CAHRRGPFGVAHWNRQIERWLAERTGQSIWSQPYAGRPLLVTAN Mvan_1208|M.vanbaalenii_PYR-1 ------CAHRRGPFGVTHWNRQVERWLADKTGQPMWSQWYPGRPLLVTAN MMAR_0956|M.marinum_M ------CAHRRGPYGIAHWNHQVQRWLTEATGEPIWSSWYAGRPVLVTAN MUL_0707|M.ulcerans_Agy99 ------CAHRRGPYGIAHWNHQVQRWLTEATGEPIWSSWYAGRPVLVTAN MAV_4544|M.avium_104 ------CAHRDGPHGAVRWNTLVHNWIAEETGQPAWSQWYAGRPLLVTAN TH_1237|M.thermoresistible__bu FTVVGDLSQRRSAAGTTSWDSMFERYVPGRWVYRTLTVNYRTPAEIMAVA ::* .. * *: .. :: * . :::. Mb0645c|M.bovis_AF2122/97 DYGLRVYNGDTGVVLAG-------------PTGLRAVISGASGPLDVATG Rv0629c|M.tuberculosis_H37Rv DYGLRVYNGDTGVVLAG-------------PTGLRAVISGASGPLDVATG MAB_0398c|M.abscessus_ATCC_199 DYGLRLYNGDTGVTVAG-------------PDGLRAVIG----AASFATS MSMEG_1325|M.smegmatis_MC2_155 DYGLKLYNGDTGVVVAT-------------PDGMRAVIGD---AGTFATG Mflv_5131|M.gilvum_PYR-GCK DYGLGVYNGDTGVVVAA-------------PEGLRAHIGTPASSRELAVG Mvan_1208|M.vanbaalenii_PYR-1 DYGLGVYNGDTGVVVAA-------------PDGLRAHVG----SLQFAPG MMAR_0956|M.marinum_M DYGLGVYNGDTGVAVLDGTN------RAAAPGALRVLIAGAQEPLKFATS MUL_0707|M.ulcerans_Agy99 DYGLGVYNGDTGVAVLDGTN------RAAAPGALRVVIAGAQEPLKFATS MAV_4544|M.avium_104 DYGLRLYNGDTGVTVAG-------------ADGLRAVIAGAAGPLDFATS TH_1237|M.thermoresistible__bu AALLAEFAPGVAPPESVRASGVPPWSRRVTADELPAAVEEFVRAEADRPG * : ... . : . : . . Mb0645c|M.bovis_AF2122/97 R---LGDVETMHAMTIHKSQGSQVDEVTVLMPQ--EDSRLLTRELLYTAV Rv0629c|M.tuberculosis_H37Rv R---LGDVETMHAMTIHKSQGSQVDEVTVLMPQ--EDSRLLTRELLYTAV MAB_0398c|M.abscessus_ATCC_199 R---LVEVETMHAMTIHKSQGSQANEVTVLLPS--EDSRLLTRELFYTAV MSMEG_1325|M.smegmatis_MC2_155 R---LTDVETMHAMTIHKSQGSQADEVTVLLPS--EDSRLLTRELFYTAV Mflv_5131|M.gilvum_PYR-GCK R---LGEVETMFAMTIHKSQGSQADEVTVLMPP--QDSRLLTRELFYTAV Mvan_1208|M.vanbaalenii_PYR-1 R---LGEVETMFAMTIHKSQGSQADEVTVLLPP--QDSRLLTRELFYTAV MMAR_0956|M.marinum_M R---LSDVETMHAMTIHKSQGSQADDVTVLLPP--ADSRLLTRELFYTAV MUL_0707|M.ulcerans_Agy99 R---LSDVETMHAMTIHKSQGSQADDVTVLLPP--ADSRLLTRELFYTAV MAV_4544|M.avium_104 R---LGEVETMHAMTIHKSQGSQADEVTVLIPP--EDSRLLTRELFYTAV TH_1237|M.thermoresistible__bu TSVVIGPPDVPGAVAPSQTKGLEFDAVLVVEPERILADGPRGAAELYVAL : :. *:: :::* : : * *: * . :*.*: Mb0645c|M.bovis_AF2122/97 ARAKRKVRVVGSEASVRAAIARRAVRASGLRMRLQSTGCG Rv0629c|M.tuberculosis_H37Rv TRAKRKVRVVGSEASVRAAIARRAVRASGLRMRLQSTGCG MAB_0398c|M.abscessus_ATCC_199 TRAKQRVRVVGSEAEVRAAIQRQAVRASGLGRRLRHSPN- MSMEG_1325|M.smegmatis_MC2_155 TRAKTRVRVVGAEAEVRAAIERQAVRATGLRKRLRPAGV- Mflv_5131|M.gilvum_PYR-GCK TRAKERVQVVGTEASVRAAVGRRAVRASGLARRLSTAR-- Mvan_1208|M.vanbaalenii_PYR-1 TRAKKHVRVVGTEASVRTAIGRRATRASGLAQRLRTRP-- MMAR_0956|M.marinum_M TRAARKVRIVGPECDVRAAIARRAIRATGLRSRLQP---- MUL_0707|M.ulcerans_Agy99 TRAARKVRIVGPECDVRAAIARRAIRATGLRSRLQP---- MAV_4544|M.avium_104 TRAKSRVRVVGPEASVRAAIERRAIRATGLRQRLRVVG-- TH_1237|M.thermoresistible__bu TRATQRLGVLHIDPLPSALSGLTPLEDPAGTPAPA----- :** :: :: : : . . ..