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MRVGPVGHQCAECVREGARAVRQPRTPFGGRQRSATPVVTYTLISLNALVFVMQVTVMGLERQLALWPPA VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTAT AGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVYAPRE RRNLIQATVTITVLVAFVVLIGWRTVDLLALFGGRLNLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0114 | - | - | 100% (249) | integral membrane protein |
| M. bovis AF2122 / 97 | Mb1372 | - | 6e-06 | 25.82% (213) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1071 | - | 4e-78 | 61.69% (248) | rhomboid family protein |
| M. tuberculosis H37Rv | Rv0110 | - | 1e-141 | 100.00% (249) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0026 | - | 2e-37 | 37.85% (214) | rhomboid family protein |
| M. marinum M | MMAR_0300 | - | 1e-113 | 77.87% (253) | serine protease |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5036 | - | 3e-88 | 64.11% (248) | rhomboid family protein |
| M. thermoresistible (build 8) | TH_2145 | - | 2e-82 | 62.92% (240) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4822 | - | 1e-113 | 78.26% (253) | serine protease |
| M. vanbaalenii PYR-1 | Mvan_5753 | - | 3e-80 | 61.04% (249) | rhomboid family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1071|M.gilvum_PYR-GCK MSSPYP--YPAQQIPTCYRHPDRQTYVRCTRCNRFICPECMRDAAVGHQC
Mvan_5753|M.vanbaalenii_PYR-1 MTYPYPPGAPYQQVPTCFRHPDRQTYVRCTRCNRFICPECMHDAAVGHQC
Mb0114|M.bovis_AF2122/97 ----------------------------------------MRVGPVGHQC
Rv0110|M.tuberculosis_H37Rv ----------------------------------------MRVGPVGHQC
MMAR_0300|M.marinum_M MSGPSA-PESPA----CYRHPGRPTYVRCTRCDRYICGDCMRSGAVGHQC
MUL_4822|M.ulcerans_Agy99 ----------------------------------------MRSGAVGHQC
MSMEG_5036|M.smegmatis_MC2_155 ----------------------------------------MRTAAVGHQC
TH_2145|M.thermoresistible__bu MSMPST-PHVPAGTPTCYRHPDRTTYVRCTRCGRYICPECMRAAAVGHQC
MAB_0026|M.abscessus_ATCC_1997 -----MAHPGQVPVYGCAWHPDRATAVRCVRCGRPVCPACMRSAPVGQQC
*: ..**:**
Mflv_1071|M.gilvum_PYR-GCK IDCVGEGMRSVRPVK---------TLTPVVTYALIGINLLAFALQMASPG
Mvan_5753|M.vanbaalenii_PYR-1 PDCVGEGARSVRPVTNAVGARPARSTTPVVTYALIGLNLLMFALQMASPD
Mb0114|M.bovis_AF2122/97 AECVREGARAVRQPRTPFGGR-QRSATPVVTYTLISLNALVFVMQVTVMG
Rv0110|M.tuberculosis_H37Rv AECVREGARAVRQPRTPFGGR-QRSATPVVTYTLISLNALVFVMQVTVMG
MMAR_0300|M.marinum_M VECVRADARTVRQPRTQFGGR-QRSVTPVVTFSLIAVSVLVFVLQLVVAG
MUL_4822|M.ulcerans_Agy99 VECVRADARTVRQPRTQFGGR-QRSVTPVVTFSLIAVSVLVFVLQLVVAG
MSMEG_5036|M.smegmatis_MC2_155 VDCVNAAARTVPEPRTRFGGK-VREGAPVLTYTLIAVNVLMFVLQIAGGD
TH_2145|M.thermoresistible__bu VECVAAAARTVRRPTTPFGGR-ISTGPPVLTYTLIAVNVLMYVLQRASTG
MAB_0026|M.abscessus_ATCC_1997 VECVQQGAKSVRQVKPLQQVR------AWITWALIAVNVLVYTATVSDGV
:** ::* . :*::**.:. * :.
Mflv_1071|M.gilvum_PYR-GCK --------LQRAFGLWSPAVADG-EMYRLLTSAFLHFGLTHLAFNMLALY
Mvan_5753|M.vanbaalenii_PYR-1 --------LDRALGLWPPAAADG-ELYRLLTSAFLHFSVTHIAFNMLALY
Mb0114|M.bovis_AF2122/97 --------LERQLALWPPAVASG-QTYRLVTSAFLHYGAMHLLLNMWALY
Rv0110|M.tuberculosis_H37Rv --------LERQLALWPPAVASG-QTYRLVTSAFLHYGAMHLLLNMWALY
MMAR_0300|M.marinum_M --------LGPHLALWPPAVADG-QLYRLVTSAFMHYGTLHLVFNMWALY
MUL_4822|M.ulcerans_Agy99 --------LGPHLALWPPAVADG-QLYRLVTSAFMHYGRLHLVFNMWALY
MSMEG_5036|M.smegmatis_MC2_155 --------LESRLTLWPPALALHDEYYRLVTSMFLHYGAMHLLFNMWALY
TH_2145|M.thermoresistible__bu --------FTEAFVLWAPAVAAG-EYYRLVTSAFLHFGLMHLLFNMFALY
MAB_0026|M.abscessus_ATCC_1997 GGDVTGSQLFRELVLYLPWVAQG-ELWRTVTTGFLHLGLMHIAVNMLSLA
: : *: * * : :* :*: *:* . *: .** :*
Mflv_1071|M.gilvum_PYR-GCK FVGPPLEAALGRARFITLYLVSALGGSVLVYLLT-LNALTAGASGAVFGL
Mvan_5753|M.vanbaalenii_PYR-1 FVGAPLEFALGRLRFVALYLFSALGGSVLVYLLT-FNALTAGASGAVFGL
Mb0114|M.bovis_AF2122/97 VVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGL
Rv0110|M.tuberculosis_H37Rv VVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGL
MMAR_0300|M.marinum_M IVGPPLEMWLGRLRFGGLYALSALGGSVLVYLIAPLNTATAGASGAIFGL
MUL_4822|M.ulcerans_Agy99 VVGPPLEMWLGRLRFGGLYALSALGGSVLVYLIAPLNTATAGASGAIFGL
MSMEG_5036|M.smegmatis_MC2_155 VVGPPLEKWLGLTRFGVLYALSGLGGSVLVYMLSPLNSATAGASGAIFGL
TH_2145|M.thermoresistible__bu VIGGPLEAALGRLRFGLLYALSALGGSVLVYLLA-MN-PTAGASGAVFGL
MAB_0026|M.abscessus_ATCC_1997 MIGPGLERAFGGQRYAAIYGTALLGSSAAAMWLS-PNAVVAGASGAIYGL
.:* ** :* *: :* : **.*. . :: * .******::**
Mflv_1071|M.gilvum_PYR-GCK FGATFVVGRKLNMDVRSVMAIIVLNLAFTFLIPLFTSQNISWQGHIGGLV
Mvan_5753|M.vanbaalenii_PYR-1 FGATFVVGKRLNMDVRSVVMIIGLNLAFTFLIPLFTSQNISWQGHIGGLV
Mb0114|M.bovis_AF2122/97 FGATFMVARRLHLDVRWVVALIVINLAFTFLAPAI-----SWQGHVGGLV
Rv0110|M.tuberculosis_H37Rv FGATFMVARRLHLDVRWVVALIVINLAFTFLAPAI-----SWQGHVGGLV
MMAR_0300|M.marinum_M FGATFVVAKRLNLDIRWVVALIAINLAITFVAPAVGSQLISWQGHVGGLI
MUL_4822|M.ulcerans_Agy99 FGATFVVAKRLNLDIRWVVALIAINLAITFVAPAVGSQLISWQGHVGGLI
MSMEG_5036|M.smegmatis_MC2_155 FGAIFVVARHLNLDVRAIGVIVVINLVFTFVGPALG-TAISWQGHIGGLV
TH_2145|M.thermoresistible__bu FAATYVVAKRLNLDVRFVTGLIVVNLVITFVVPGI-----SWQGHLGGLL
MAB_0026|M.abscessus_ATCC_1997 LGAALVLSLRERLNPQTIIIVLLLNIGLSISLPGIS-----LAGHMGGLL
:.* ::. : .:: : : :: :*: ::: * . **:***:
Mflv_1071|M.gilvum_PYR-GCK TGALVAAAFAYAPRAQRTLIQAGAVGAILVVFVGLIVWRTAELRTLMGLG
Mvan_5753|M.vanbaalenii_PYR-1 TGAVVAAAFVYAPRQQRNLVQAGAAVALLVLFVALVAWRTVELRTMLGLG
Mb0114|M.bovis_AF2122/97 TGALVAATYVYAPRERRNLIQATVTITVLVAFVVLIGWRTVDLLALFGGR
Rv0110|M.tuberculosis_H37Rv TGALVAATYVYAPRERRNLIQATVTITVLVAFVVLIGWRTVDLLALFGGR
MMAR_0300|M.marinum_M TGALVAAAYVYAPRERRNFIQGAVTLTVAVAFVVLIWWRTSELLAMFGGH
MUL_4822|M.ulcerans_Agy99 TGALVAAAYVYAPRERRNFIQGAVTLTVAVAFVVLIWWRTSELLAMFGGH
MSMEG_5036|M.smegmatis_MC2_155 TGALVASAFVYAPRERRTATAAGVTVAFAMLFAALIFWRTDRLLFLLGAG
TH_2145|M.thermoresistible__bu TGALVAAAFAYPPPARRNAVQAATVVTLVLLFAVLIWVRTDVLLATWMTH
MAB_0026|M.abscessus_ATCC_1997 FGVLSAGALLYYREVCRGIGMPDLARKASTPWVLAAVVAALSVALIMAKV
*.: *.: * * . :. : :
Mflv_1071|M.gilvum_PYR-GCK -----
Mvan_5753|M.vanbaalenii_PYR-1 -----
Mb0114|M.bovis_AF2122/97 LNLS-
Rv0110|M.tuberculosis_H37Rv LNLS-
MMAR_0300|M.marinum_M LNLG-
MUL_4822|M.ulcerans_Agy99 LNLG-
MSMEG_5036|M.smegmatis_MC2_155 -----
TH_2145|M.thermoresistible__bu F----
MAB_0026|M.abscessus_ATCC_1997 LAYAG