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MAHPGQVPVYGCAWHPDRATAVRCVRCGRPVCPACMRSAPVGQQCVECVQQGAKSVRQVKPLQQVRAWIT WALIAVNVLVYTATVSDGVGGDVTGSQLFRELVLYLPWVAQGELWRTVTTGFLHLGLMHIAVNMLSLAMI GPGLERAFGGQRYAAIYGTALLGSSAAAMWLSPNAVVAGASGAIYGLLGAALVLSLRERLNPQTIIIVLL LNIGLSISLPGISLAGHMGGLLFGVLSAGALLYYREVCRGIGMPDLARKASTPWVLAAVVAALSVALIMA KVLAYAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0026 | - | - | 100% (287) | rhomboid family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0114 | - | 2e-37 | 37.85% (214) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1071 | - | 2e-49 | 41.56% (243) | rhomboid family protein |
| M. tuberculosis H37Rv | Rv0110 | - | 2e-37 | 37.85% (214) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0300 | - | 4e-43 | 38.82% (255) | serine protease |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5036 | - | 3e-31 | 37.44% (219) | rhomboid family protein |
| M. thermoresistible (build 8) | TH_2145 | - | 5e-46 | 43.04% (237) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4822 | - | 3e-34 | 38.18% (220) | serine protease |
| M. vanbaalenii PYR-1 | Mvan_5753 | - | 3e-46 | 40.16% (249) | rhomboid family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0114|M.bovis_AF2122/97 ----------------------------------------MRVGPVGHQC
Rv0110|M.tuberculosis_H37Rv ----------------------------------------MRVGPVGHQC
MMAR_0300|M.marinum_M MSGPSA-PESPA----CYRHPGRPTYVRCTRCDRYICGDCMRSGAVGHQC
MUL_4822|M.ulcerans_Agy99 ----------------------------------------MRSGAVGHQC
MSMEG_5036|M.smegmatis_MC2_155 ----------------------------------------MRTAAVGHQC
TH_2145|M.thermoresistible__bu MSMPST-PHVPAGTPTCYRHPDRTTYVRCTRCGRYICPECMRAAAVGHQC
Mflv_1071|M.gilvum_PYR-GCK MSSPYP--YPAQQIPTCYRHPDRQTYVRCTRCNRFICPECMRDAAVGHQC
Mvan_5753|M.vanbaalenii_PYR-1 MTYPYPPGAPYQQVPTCFRHPDRQTYVRCTRCNRFICPECMHDAAVGHQC
MAB_0026|M.abscessus_ATCC_1997 -----MAHPGQVPVYGCAWHPDRATAVRCVRCGRPVCPACMRSAPVGQQC
*: ..**:**
Mb0114|M.bovis_AF2122/97 AECVREGARAVRQPRTPFGGR-QRSATPVVTYTLISLNALVFVMQVTVMG
Rv0110|M.tuberculosis_H37Rv AECVREGARAVRQPRTPFGGR-QRSATPVVTYTLISLNALVFVMQVTVMG
MMAR_0300|M.marinum_M VECVRADARTVRQPRTQFGGR-QRSVTPVVTFSLIAVSVLVFVLQLVVAG
MUL_4822|M.ulcerans_Agy99 VECVRADARTVRQPRTQFGGR-QRSVTPVVTFSLIAVSVLVFVLQLVVAG
MSMEG_5036|M.smegmatis_MC2_155 VDCVNAAARTVPEPRTRFGGK-VREGAPVLTYTLIAVNVLMFVLQIAGGD
TH_2145|M.thermoresistible__bu VECVAAAARTVRRPTTPFGGR-ISTGPPVLTYTLIAVNVLMYVLQRASTG
Mflv_1071|M.gilvum_PYR-GCK IDCVGEGMRSVRPVK---------TLTPVVTYALIGINLLAFALQMASPG
Mvan_5753|M.vanbaalenii_PYR-1 PDCVGEGARSVRPVTNAVGARPARSTTPVVTYALIGLNLLMFALQMASPD
MAB_0026|M.abscessus_ATCC_1997 VECVQQGAKSVRQVKPLQQVR------AWITWALIAVNVLVYTATVSDGV
:** ::* . :*::**.:. * :.
Mb0114|M.bovis_AF2122/97 --------LERQLALWPPAVASG-QTYRLVTSAFLHYGAMHLLLNMWALY
Rv0110|M.tuberculosis_H37Rv --------LERQLALWPPAVASG-QTYRLVTSAFLHYGAMHLLLNMWALY
MMAR_0300|M.marinum_M --------LGPHLALWPPAVADG-QLYRLVTSAFMHYGTLHLVFNMWALY
MUL_4822|M.ulcerans_Agy99 --------LGPHLALWPPAVADG-QLYRLVTSAFMHYGRLHLVFNMWALY
MSMEG_5036|M.smegmatis_MC2_155 --------LESRLTLWPPALALHDEYYRLVTSMFLHYGAMHLLFNMWALY
TH_2145|M.thermoresistible__bu --------FTEAFVLWAPAVAAG-EYYRLVTSAFLHFGLMHLLFNMFALY
Mflv_1071|M.gilvum_PYR-GCK --------LQRAFGLWSPAVADG-EMYRLLTSAFLHFGLTHLAFNMLALY
Mvan_5753|M.vanbaalenii_PYR-1 --------LDRALGLWPPAAADG-ELYRLLTSAFLHFSVTHIAFNMLALY
MAB_0026|M.abscessus_ATCC_1997 GGDVTGSQLFRELVLYLPWVAQG-ELWRTVTTGFLHLGLMHIAVNMLSLA
: : *: * * : :* :*: *:* . *: .** :*
Mb0114|M.bovis_AF2122/97 VVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGL
Rv0110|M.tuberculosis_H37Rv VVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGL
MMAR_0300|M.marinum_M IVGPPLEMWLGRLRFGGLYALSALGGSVLVYLIAPLNTATAGASGAIFGL
MUL_4822|M.ulcerans_Agy99 VVGPPLEMWLGRLRFGGLYALSALGGSVLVYLIAPLNTATAGASGAIFGL
MSMEG_5036|M.smegmatis_MC2_155 VVGPPLEKWLGLTRFGVLYALSGLGGSVLVYMLSPLNSATAGASGAIFGL
TH_2145|M.thermoresistible__bu VIGGPLEAALGRLRFGLLYALSALGGSVLVYLLA-MN-PTAGASGAVFGL
Mflv_1071|M.gilvum_PYR-GCK FVGPPLEAALGRARFITLYLVSALGGSVLVYLLT-LNALTAGASGAVFGL
Mvan_5753|M.vanbaalenii_PYR-1 FVGAPLEFALGRLRFVALYLFSALGGSVLVYLLT-FNALTAGASGAVFGL
MAB_0026|M.abscessus_ATCC_1997 MIGPGLERAFGGQRYAAIYGTALLGSSAAAMWLS-PNAVVAGASGAIYGL
.:* ** :* *: :* : **.*. . :: * .******::**
Mb0114|M.bovis_AF2122/97 FGATFMVARRLHLDVRWVVALIVINLAFTFLAPAI-----SWQGHVGGLV
Rv0110|M.tuberculosis_H37Rv FGATFMVARRLHLDVRWVVALIVINLAFTFLAPAI-----SWQGHVGGLV
MMAR_0300|M.marinum_M FGATFVVAKRLNLDIRWVVALIAINLAITFVAPAVGSQLISWQGHVGGLI
MUL_4822|M.ulcerans_Agy99 FGATFVVAKRLNLDIRWVVALIAINLAITFVAPAVGSQLISWQGHVGGLI
MSMEG_5036|M.smegmatis_MC2_155 FGAIFVVARHLNLDVRAIGVIVVINLVFTFVGPALG-TAISWQGHIGGLV
TH_2145|M.thermoresistible__bu FAATYVVAKRLNLDVRFVTGLIVVNLVITFVVPGI-----SWQGHLGGLL
Mflv_1071|M.gilvum_PYR-GCK FGATFVVGRKLNMDVRSVMAIIVLNLAFTFLIPLFTSQNISWQGHIGGLV
Mvan_5753|M.vanbaalenii_PYR-1 FGATFVVGKRLNMDVRSVVMIIGLNLAFTFLIPLFTSQNISWQGHIGGLV
MAB_0026|M.abscessus_ATCC_1997 LGAALVLSLRERLNPQTIIIVLLLNIGLSISLPGIS-----LAGHMGGLL
:.* ::. : .:: : : :: :*: ::: * . **:***:
Mb0114|M.bovis_AF2122/97 TGALVAATYVYAPRERRNLIQATVTITVLVAFVVLIGWRTVDLLALFGGR
Rv0110|M.tuberculosis_H37Rv TGALVAATYVYAPRERRNLIQATVTITVLVAFVVLIGWRTVDLLALFGGR
MMAR_0300|M.marinum_M TGALVAAAYVYAPRERRNFIQGAVTLTVAVAFVVLIWWRTSELLAMFGGH
MUL_4822|M.ulcerans_Agy99 TGALVAAAYVYAPRERRNFIQGAVTLTVAVAFVVLIWWRTSELLAMFGGH
MSMEG_5036|M.smegmatis_MC2_155 TGALVASAFVYAPRERRTATAAGVTVAFAMLFAALIFWRTDRLLFLLGAG
TH_2145|M.thermoresistible__bu TGALVAAAFAYPPPARRNAVQAATVVTLVLLFAVLIWVRTDVLLATWMTH
Mflv_1071|M.gilvum_PYR-GCK TGALVAAAFAYAPRAQRTLIQAGAVGAILVVFVGLIVWRTAELRTLMGLG
Mvan_5753|M.vanbaalenii_PYR-1 TGAVVAAAFVYAPRQQRNLVQAGAAVALLVLFVALVAWRTVELRTMLGLG
MAB_0026|M.abscessus_ATCC_1997 FGVLSAGALLYYREVCRGIGMPDLARKASTPWVLAAVVAALSVALIMAKV
*.: *.: * * . :. : :
Mb0114|M.bovis_AF2122/97 LNLS-
Rv0110|M.tuberculosis_H37Rv LNLS-
MMAR_0300|M.marinum_M LNLG-
MUL_4822|M.ulcerans_Agy99 LNLG-
MSMEG_5036|M.smegmatis_MC2_155 -----
TH_2145|M.thermoresistible__bu F----
Mflv_1071|M.gilvum_PYR-GCK -----
Mvan_5753|M.vanbaalenii_PYR-1 -----
MAB_0026|M.abscessus_ATCC_1997 LAYAG