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VPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAI AGAFAVLFLPYSLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLAR FVASGLSAALPHVVPREQVVTMNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIAL LWSLRFGPRVLGPDDTERAIHGSAVYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLV RHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAAAATIQVAAAGLLVPVMVVC GFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAI YLAGLVVHTIVGRRGQPVIGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0038c | - | - | 100% (441) | integral membrane protein |
| M. bovis AF2122 / 97 | Mb1288c | - | 3e-07 | 23.98% (392) | integral membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0849 | - | 1e-164 | 65.48% (420) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0037c | - | 0.0 | 100.00% (441) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4929 | - | 1e-134 | 59.12% (411) | hypothetical protein MAB_4929 |
| M. marinum M | MMAR_0052 | - | 0.0 | 84.32% (421) | integral membrane protein |
| M. avium 104 | MAV_0051 | - | 0.0 | 80.14% (428) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_6922 | - | 1e-157 | 66.11% (419) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | TH_1986 | - | 2e-06 | 21.55% (413) | tetracycline-resistance determinant TetV |
| M. ulcerans Agy99 | MUL_0051 | - | 0.0 | 83.61% (421) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_6058 | - | 1e-166 | 66.03% (421) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0038c|M.bovis_AF2122/97 ----------------MPRVEVGLVIHSRMHARAPVDVWRSVR--SLPDF
Rv0037c|M.tuberculosis_H37Rv ----------------MPRVEVGLVIHSRMHARAPVDVWRSVR--SLPDF
MMAR_0052|M.marinum_M -----------------------------MHASAPVELWRSVR--SLPDF
MUL_0051|M.ulcerans_Agy99 -----------------------------MHASAPVELWRSVR--SLPDF
MAV_0051|M.avium_104 ------------------------MIPTRMQSSAPVEIWRSVR--ALPDF
Mflv_0849|M.gilvum_PYR-GCK MANERSPVAYLYCGSGSARPHPPQDVTPVPDDRAPRTSWRAVQ--ALPQF
Mvan_6058|M.vanbaalenii_PYR-1 ----------------------------MPDDRAPRTLWRSVR--ALPEF
MSMEG_6922|M.smegmatis_MC2_155 -------------------------MIFVVDARAPIALWRSLR--AMTEF
MAB_4929|M.abscessus_ATCC_1997 ----------------------------MTARHSPLSLWRAIH--DLPDF
TH_1986|M.thermoresistible__bu ----------------------VSTQYDIEPSAGTSGGWRVLAPFRIREY
.. ** : : ::
Mb0038c|M.bovis_AF2122/97 WRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYS
Rv0037c|M.tuberculosis_H37Rv WRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYS
MMAR_0052|M.marinum_M WRLLQVRIASQFGDGLFQAGLAGALLFNPDRAADPMAIARAFAVLFLPYS
MUL_0051|M.ulcerans_Agy99 WRLLQVRIASQFGDGLFQAGLAGALLFNPDRAADPMAIARAFAVLFLPYS
MAV_0051|M.avium_104 WRLLQVRVASQFGDGLFQAALAGALLFNPDRAADPLAIARAFTVLFLPYS
Mflv_0849|M.gilvum_PYR-GCK RRLLELRAVSQFAEGLFQAGIAGALLFNPEREADPWAIAGAFAALFLPYS
Mvan_6058|M.vanbaalenii_PYR-1 RRLLELRAVSQFGDGLFQAGIAGAILFNPEREAEPWAIAAAFAVLFLPYS
MSMEG_6922|M.smegmatis_MC2_155 RRLLELRAVSQFGDGLFQAGLAGAILFNVERAAGPWQIAGSFAVLFLPYS
MAB_4929|M.abscessus_ATCC_1997 GRLVWVRLLTQFSDGLFQAGLAGALLFNPEREAEPWAIAGAFAVLFLPYS
TH_1986|M.thermoresistible__bu RLLITAVAITIFAEGMWAVVMALQVIAIDNDPASLSLVATCMGVGLVAFV
*: : *.:*:: . :* :: : * :* .: . ::.:
Mb0038c|M.bovis_AF2122/97 LLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGA
Rv0037c|M.tuberculosis_H37Rv LLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGA
MMAR_0052|M.marinum_M LLGPFAGALMDRWDRRLVIVGANIGRLILIAGIGTILAFEAGDLLLLFVA
MUL_0051|M.ulcerans_Agy99 LLGPFAGALMDRWDRRLVIVGANIGRLILIAGIGTILAFEAGDLLLLFVA
MAV_0051|M.avium_104 LLGPFAGALMDRWDRRLVLVGANVGRLVLIAAIGTILAVRAGDLSLLLGA
Mflv_0849|M.gilvum_PYR-GCK LLGPFAGALLDRWDRRLVLIGANTGRVAIVLLVGVLLAAGAGDIPILLSA
Mvan_6058|M.vanbaalenii_PYR-1 LLGPFAGALLDRWDRRLVLIGANCGRLVVILVVGALLSAGLSDIPILLSA
MSMEG_6922|M.smegmatis_MC2_155 ALGPFAGALLDRWDRRLVMIGANLGRLLLVVLVGVLLALGAGDLEILCCA
MAB_4929|M.abscessus_ATCC_1997 AIGPFAGALLDRWDRRAVLICANLIRVLLVALVGFELAFSADDVVLLLGA
TH_1986|M.thermoresistible__bu LVG---GITADRINQRTIIIAVEAVNAVTVAVVAMLGLTGQLRIWHLAVA
:* * ** ::* ::: .: . : :. : * *
Mb0038c|M.bovis_AF2122/97 LVANGLAR-FVASGLSAALPHVVPREQVVTMNSVAIASGAVSAFLGANFM
Rv0037c|M.tuberculosis_H37Rv LVANGLAR-FVASGLSAALPHVVPREQVVTMNSVAIASGAVSAFLGANFM
MMAR_0052|M.marinum_M LLANGLAR-FVASGLSASLPHVVPREQVVTMNSVATASGAVAAFVGANFM
MUL_0051|M.ulcerans_Agy99 LLANGLAR-FVASGLSASLPHVVPREQVVTMNSVATASGAVAAFVGANFM
MAV_0051|M.avium_104 LFANGLAR-FVGSGLSASLPHVVPREQVVTMNAVATAAGAVAAFLGANFM
Mflv_0849|M.gilvum_PYR-GCK LVANGFTR-FVSSGLSAALPHVVPREQVIPMNSVANLISSIGAFAGAVFM
Mvan_6058|M.vanbaalenii_PYR-1 LLANGFTR-FVSSGLSAALPHVVPRDQVIAMNSVATATTSIAAFAGAIFM
MSMEG_6922|M.smegmatis_MC2_155 LIINGFTR-FVSSGLSAALPDVVPRGQVVAMNSVATATGAAAAFLGANFM
MAB_4929|M.abscessus_ATCC_1997 LIVNGVTR-FVTSGLSAALPHVVPRDQVATMNSVATAVGATATFIGANFM
TH_1986|M.thermoresistible__bu AAVLGIAAAFFFPAYSALLPRILPPEQLLAANGVEGVVR--PVFQRAVGP
*.: *. .. ** ** ::* *: . *.* .* *
Mb0038c|M.bovis_AF2122/97 LLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIH
Rv0037c|M.tuberculosis_H37Rv LLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIH
MMAR_0052|M.marinum_M LLPRWLAGGGDHGAAAVIFTAMIPVAISLLLALRFAPRVLGPDDTKRAIH
MUL_0051|M.ulcerans_Agy99 LLPRWLAGGGDHGAAAVIFTAMIPVAISLLLALRFAPRVLGPDDTKRAIH
MAV_0051|M.avium_104 LVPRFLFGAGDRGAAAIVFLTVVPVSIALLLSWRFAPRALGPDDTWRAIH
Mflv_0849|M.gilvum_PYR-GCK LGPRWLFGAGDSGASITILMVTVPVGLALWLSMRFPPRLLGPDDSKRAVH
Mvan_6058|M.vanbaalenii_PYR-1 LLPRWLFGAGDSGASVIIFMVAVPVSVALWLSMRFPPRLLGPDDSARAVH
MSMEG_6922|M.smegmatis_MC2_155 LLPRWLFGAGDAGASVVIFIVLIPVALALWLSVRFGPHVLGPHESKRAIH
MAB_4929|M.abscessus_ATCC_1997 LMLRAAFGAGDLGSATVIFLVIVPTTAAAWVASGFPGDRLGPDDSVRAVH
TH_1986|M.thermoresistible__bu AVAGMLVGATFPSLGSAVVATLFGVGLVLLVATRPP--------ASPSVP
*. . . :. . . . : : ::
Mb0038c|M.bovis_AF2122/97 GSAVYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVR
Rv0037c|M.tuberculosis_H37Rv GSAVYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVR
MMAR_0052|M.marinum_M GSAVYAVITGWMHGVRTVVQLPTVAAALSGLAAHRMVVGVNSLLILLLVH
MUL_0051|M.ulcerans_Agy99 GSAVYAVITGWMHGVRTVVQIPTVAAALSGLAAHRMVVGVNSLLILLLVH
MAV_0051|M.avium_104 GPVLYAVITGWLHGARTVAQRPTVAATLSGLAAHRMVVGINSLLVLLLVH
Mflv_0849|M.gilvum_PYR-GCK GSVMYAVATGWLYGARTVLAVPTAASTLAGLAAHRMVFGINTLLMLVIVR
Mvan_6058|M.vanbaalenii_PYR-1 GSVLYAVATGWLHGARTVLAVPSVSSTLSGLAAHRMVFGVNTLLVLVMVR
MSMEG_6922|M.smegmatis_MC2_155 GSVAYAVSTGWLHGARTVASVRTVAATLGGLAAHRAAFGINTLIVLVLVR
MAB_4929|M.abscessus_ATCC_1997 GSAFYAVATGWLHGARTIVGTPSVFDALIGLAAHRMVFGVNTLLVLVLVR
TH_1986|M.thermoresistible__bu GEHRSRVLRDLRDGFMFMVATPWLLWTLLFASVFVLVVLGPIEVLLPFIA
* * . * : * :.. .. ::* ::
Mb0038c|M.bovis_AF2122/97 HVTARAVGG---LGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGA
Rv0037c|M.tuberculosis_H37Rv HVTARAVGG---LGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGA
MMAR_0052|M.marinum_M HMRDVDVEG---LGTALLFFAATGLGAFLANVLTPGLIRRWGRYATTNGA
MUL_0051|M.ulcerans_Agy99 HMRDVDVEG---LGTALLFFAATGLGAFLANVLTPGLIRRWGRYATTNGA
MAV_0051|M.avium_104 HLPGLEGGG---FGTALLFFGAAGLGAFLANVLTPPAIRRWGRYATANGA
Mflv_0849|M.gilvum_PYR-GCK HTETATVAG---FGTTVLFVIAGGAGQFVATIATPALVTRWGRYAAPNGA
Mvan_6058|M.vanbaalenii_PYR-1 HTEAATVAG---FGTTVLFVSAGGAGQFLATVVTPTLVKKWGRYATPNGA
MSMEG_6922|M.smegmatis_MC2_155 HTDTPTQVAGVGLGTAVVFVGATGAGTFLATLVMPAVVARFGRYATANGA
MAB_4929|M.abscessus_ATCC_1997 SNES-VFAG---IGAAALFLACTGIGSFLGTVSTPALLRRFGRGRTLGMA
TH_1986|M.thermoresistible__bu QERFTDGAR---MYGFVLAAFGVGSAVGALTVSSRQMPRRYLTVMMLMWA
: : * . .: :: *
Mb0038c|M.bovis_AF2122/97 LAAAATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALR
Rv0037c|M.tuberculosis_H37Rv LAAAATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALR
MMAR_0052|M.marinum_M LAAAAVIQLAGAGLLLPVMVVCGFLLGVAGQVVKLCADSAMQIDVDDALR
MUL_0051|M.ulcerans_Agy99 LAAAAVTQLAGAGLLLPVMVVCGFLLGVAGQVVKLCADSAMQIDVDGALR
MAV_0051|M.avium_104 LAASAIIEVAGAELLLPVMVVCGFLLGVTGQMVKLCADSAMQMDVDDALR
Mflv_0849|M.gilvum_PYR-GCK LALAAVVQVCAATLQLPVMIVCGFVLGAAGQVVKLCADSAMQIDVDDALR
Mvan_6058|M.vanbaalenii_PYR-1 LAFAAAVQLCGATLNLPVMIVCGFLLGAAGQVVKLCADTAMQIDVEDALR
MSMEG_6922|M.smegmatis_MC2_155 LAFAALVQAVALSLHLPVMLVCGFLLGAAGQFVKLCADSAMQIDVDDALR
MAB_4929|M.abscessus_ATCC_1997 LGGAVVLQLIASGLYIPILLASAFGLGMAGQVIKLCADVGMQTDVDDALR
TH_1986|M.thermoresistible__bu LG-SVPLLVIGFTWSFLLMSAASFAIGVTDGAGMVIWGTLLQRRVPRELL
*. :. . . :: ...* :* :. : . :* * *
Mb0038c|M.bovis_AF2122/97 GHVFAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVH
Rv0037c|M.tuberculosis_H37Rv GHVFAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVH
MMAR_0052|M.marinum_M GHVFAVQDALFWVSYIVSVTVAAALIPDDGRAPVFVLVGSVIYLIGLCVH
MUL_0051|M.ulcerans_Agy99 GHVFAVQDALFWVSYIVSVTVAAALIPDDGRAPVFVLVGSLIYLLGLCVH
MAV_0051|M.avium_104 GHVFAVQDALFWVAFIVAITVAGMVIPDDGHAPVFALFGSVLYLVGLAVH
Mflv_0849|M.gilvum_PYR-GCK GHMFAVQDSLFWVAFIVAITGAAAVIPADGHSPALAVAGTGLYLAGLAAH
Mvan_6058|M.vanbaalenii_PYR-1 GHLFAVQDALFWLAFIVAISAAAFVIPPDGRSVGLAVAGVGTYLAGLAVH
MSMEG_6922|M.smegmatis_MC2_155 GHVFTVQDALFWMSFVCAIAVAALVIAPDGHSPGLVAAGSVIYLAGLGLH
MAB_4929|M.abscessus_ATCC_1997 GHVFAVQDSLFWVTFTGAMAVGAAFIT---HAHWLAFSGAMIYLAGLIVH
TH_1986|M.thermoresistible__bu GRVSSLDFFVSLVFMPVSFAIAGPLSKVVSMQTIFLVAGLAPLLFAVVAM
*:: ::: : : :.: .. . : * * .:
Mb0038c|M.bovis_AF2122/97 TIVGRRGQP--VIGR------------------------
Rv0037c|M.tuberculosis_H37Rv TIVGRRGQP--VIGR------------------------
MMAR_0052|M.marinum_M SIVGRRSSAANVEGG------------------------
MUL_0051|M.ulcerans_Agy99 SIVGRRSSASNVEGC------------------------
MAV_0051|M.avium_104 GIVGRRGE-------------------------------
Mflv_0849|M.gilvum_PYR-GCK AVMGRRGR-RG----------------------------
Mvan_6058|M.vanbaalenii_PYR-1 ATVGRRGRPRG----------------------------
MSMEG_6922|M.smegmatis_MC2_155 AFVASPRRA------------------------------
MAB_4929|M.abscessus_ATCC_1997 MTRTLWPSTLDTGSLPTQPNAGSLPTQPNPEGQARDLDR
TH_1986|M.thermoresistible__bu TAARMPRDELEHPLN------------------------