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IPTRMQSSAPVEIWRSVRALPDFWRLLQVRVASQFGDGLFQAALAGALLFNPDRAADPLAIARAFTVLFL PYSLLGPFAGALMDRWDRRLVLVGANVGRLVLIAAIGTILAVRAGDLSLLLGALFANGLARFVGSGLSAS LPHVVPREQVVTMNAVATAAGAVAAFLGANFMLVPRFLFGAGDRGAAAIVFLTVVPVSIALLLSWRFAPR ALGPDDTWRAIHGPVLYAVITGWLHGARTVAQRPTVAATLSGLAAHRMVVGINSLLVLLLVHHLPGLEGG GFGTALLFFGAAGLGAFLANVLTPPAIRRWGRYATANGALAASAIIEVAGAELLLPVMVVCGFLLGVTGQ MVKLCADSAMQMDVDDALRGHVFAVQDALFWVAFIVAITVAGMVIPDDGHAPVFALFGSVLYLVGLAVHG IVGRRGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0051 | - | - | 100% (428) | transporter, major facilitator family protein |
| M. avium 104 | MAV_1406 | - | 5e-05 | 23.63% (402) | transporter, major facilitator family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0038c | - | 0.0 | 80.14% (428) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0849 | - | 1e-157 | 64.35% (418) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0037c | - | 0.0 | 80.14% (428) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4929 | - | 1e-127 | 55.96% (411) | hypothetical protein MAB_4929 |
| M. marinum M | MMAR_0052 | - | 0.0 | 80.05% (421) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_6922 | - | 1e-152 | 63.18% (421) | transporter, major facilitator family protein |
| M. thermoresistible (build 8) | TH_1317 | - | 7e-09 | 24.59% (366) | transmembrane transport protein |
| M. ulcerans Agy99 | MUL_0051 | - | 0.0 | 79.33% (421) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_6058 | - | 1e-162 | 66.51% (418) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0038c|M.bovis_AF2122/97 ----------------MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWR
Rv0037c|M.tuberculosis_H37Rv ----------------MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWR
MMAR_0052|M.marinum_M -----------------------------MHASAPVELWRSVRSLPDFWR
MUL_0051|M.ulcerans_Agy99 -----------------------------MHASAPVELWRSVRSLPDFWR
MAV_0051|M.avium_104 ------------------------MIPTRMQSSAPVEIWRSVRALPDFWR
Mflv_0849|M.gilvum_PYR-GCK MANERSPVAYLYCGSGSARPHPPQDVTPVPDDRAPRTSWRAVQALPQFRR
Mvan_6058|M.vanbaalenii_PYR-1 ----------------------------MPDDRAPRTLWRSVRALPEFRR
MSMEG_6922|M.smegmatis_MC2_155 -------------------------MIFVVDARAPIALWRSLRAMTEFRR
MAB_4929|M.abscessus_ATCC_1997 ----------------------------MTARHSPLSLWRAIHDLPDFGR
TH_1317|M.thermoresistible__bu ---LWIAQFVSNLGTWMQTVGAQWMLVSTPAAEVLVPLVQTATTLPIMLL
:: :. :
Mb0038c|M.bovis_AF2122/97 LLQVRVASQFGDG-----LFQAGLAGALLFNPDRAADPMAIAGAFAVLFL
Rv0037c|M.tuberculosis_H37Rv LLQVRVASQFGDG-----LFQAGLAGALLFNPDRAADPMAIAGAFAVLFL
MMAR_0052|M.marinum_M LLQVRIASQFGDG-----LFQAGLAGALLFNPDRAADPMAIARAFAVLFL
MUL_0051|M.ulcerans_Agy99 LLQVRIASQFGDG-----LFQAGLAGALLFNPDRAADPMAIARAFAVLFL
MAV_0051|M.avium_104 LLQVRVASQFGDG-----LFQAALAGALLFNPDRAADPLAIARAFTVLFL
Mflv_0849|M.gilvum_PYR-GCK LLELRAVSQFAEG-----LFQAGIAGALLFNPEREADPWAIAGAFAALFL
Mvan_6058|M.vanbaalenii_PYR-1 LLELRAVSQFGDG-----LFQAGIAGAILFNPEREAEPWAIAAAFAVLFL
MSMEG_6922|M.smegmatis_MC2_155 LLELRAVSQFGDG-----LFQAGLAGAILFNVERAAGPWQIAGSFAVLFL
MAB_4929|M.abscessus_ATCC_1997 LVWVRLLTQFSDG-----LFQAGLAGALLFNPEREAEPWAIAGAFAVLFL
TH_1317|M.thermoresistible__bu SLPSGVVADLVDRRRLLLATQSMMAAAVAILAALTAAQLTTPTVLLILLF
: ::: : *: :*.*: : * . : *::
Mb0038c|M.bovis_AF2122/97 PYSLLGPFAGALMDRWDRRWVLVG------------ANTGRLALIAGVGT
Rv0037c|M.tuberculosis_H37Rv PYSLLGPFAGALMDRWDRRWVLVG------------ANTGRLALIAGVGT
MMAR_0052|M.marinum_M PYSLLGPFAGALMDRWDRRLVIVG------------ANIGRLILIAGIGT
MUL_0051|M.ulcerans_Agy99 PYSLLGPFAGALMDRWDRRLVIVG------------ANIGRLILIAGIGT
MAV_0051|M.avium_104 PYSLLGPFAGALMDRWDRRLVLVG------------ANVGRLVLIAAIGT
Mflv_0849|M.gilvum_PYR-GCK PYSLLGPFAGALLDRWDRRLVLIG------------ANTGRVAIVLLVGV
Mvan_6058|M.vanbaalenii_PYR-1 PYSLLGPFAGALLDRWDRRLVLIG------------ANCGRLVVILVVGA
MSMEG_6922|M.smegmatis_MC2_155 PYSALGPFAGALLDRWDRRLVMIG------------ANLGRLLLVVLVGV
MAB_4929|M.abscessus_ATCC_1997 PYSAIGPFAGALLDRWDRRAVLIC------------ANLIRVLLVALVGF
TH_1317|M.thermoresistible__bu LIGCGQAFTAPAWQAIQPELVPREQIPAAAALTSMSLNAARAVGPAVAGV
. .*:.. : : . * * * *
Mb0038c|M.bovis_AF2122/97 ILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVVTMNSVAI
Rv0037c|M.tuberculosis_H37Rv ILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVVTMNSVAI
MMAR_0052|M.marinum_M ILAFEAGDLLLLFVALLANGLARFVASGLSASLPHVVPREQVVTMNSVAT
MUL_0051|M.ulcerans_Agy99 ILAFEAGDLLLLFVALLANGLARFVASGLSASLPHVVPREQVVTMNSVAT
MAV_0051|M.avium_104 ILAVRAGDLSLLLGALFANGLARFVGSGLSASLPHVVPREQVVTMNAVAT
Mflv_0849|M.gilvum_PYR-GCK LLAAGAGDIPILLSALVANGFTRFVSSGLSAALPHVVPREQVIPMNSVAN
Mvan_6058|M.vanbaalenii_PYR-1 LLSAGLSDIPILLSALLANGFTRFVSSGLSAALPHVVPRDQVIAMNSVAT
MSMEG_6922|M.smegmatis_MC2_155 LLALGAGDLEILCCALIINGFTRFVSSGLSAALPDVVPRGQVVAMNSVAT
MAB_4929|M.abscessus_ATCC_1997 ELAFSADDVVLLLGALIVNGVTRFVTSGLSAALPHVVPRDQVATMNSVAT
TH_1317|M.thermoresistible__bu LVAISGPTLVFTLNAVSFAGIVVVLLLWKRSSAEQTLAAERPLAALQAGH
:: : : *: *.. .: :: ..:. : . ..
Mb0038c|M.bovis_AF2122/97 ASGAVSAFLGANFMLLPRWLLGS----GDEGASAIVFLVAIPVSIALLWS
Rv0037c|M.tuberculosis_H37Rv ASGAVSAFLGANFMLLPRWLLGS----GDEGASAIVFLVAIPVSIALLWS
MMAR_0052|M.marinum_M ASGAVAAFVGANFMLLPRWLAGG----GDHGAAAVIFTAMIPVAISLLLA
MUL_0051|M.ulcerans_Agy99 ASGAVAAFVGANFMLLPRWLAGG----GDHGAAAVIFTAMIPVAISLLLA
MAV_0051|M.avium_104 AAGAVAAFLGANFMLVPRFLFGA----GDRGAAAIVFLTVVPVSIALLLS
Mflv_0849|M.gilvum_PYR-GCK LISSIGAFAGAVFMLGPRWLFGA----GDSGASITILMVTVPVGLALWLS
Mvan_6058|M.vanbaalenii_PYR-1 ATTSIAAFAGAIFMLLPRWLFGA----GDSGASVIIFMVAVPVSVALWLS
MSMEG_6922|M.smegmatis_MC2_155 ATGAAAAFLGANFMLLPRWLFGA----GDAGASVVIFIVLIPVALALWLS
MAB_4929|M.abscessus_ATCC_1997 AVGATATFIGANFMLMLRAAFGA----GDLGSATVIFLVIVPTTAAAWVA
TH_1317|M.thermoresistible__bu RYVRSSPVVRRILFRAALFILPASALWGLLPVVASSGLGLSSSGYGLMLG
... :: . * . . .
Mb0038c|M.bovis_AF2122/97 LRFGPRVLGPDDT----ERAIHGSAVYAVVTGWLHGARTVVQLPTVAAGL
Rv0037c|M.tuberculosis_H37Rv LRFGPRVLGPDDT----ERAIHGSAVYAVVTGWLHGARTVVQLPTVAAGL
MMAR_0052|M.marinum_M LRFAPRVLGPDDT----KRAIHGSAVYAVITGWMHGVRTVVQLPTVAAAL
MUL_0051|M.ulcerans_Agy99 LRFAPRVLGPDDT----KRAIHGSAVYAVITGWMHGVRTVVQIPTVAAAL
MAV_0051|M.avium_104 WRFAPRALGPDDT----WRAIHGPVLYAVITGWLHGARTVAQRPTVAATL
Mflv_0849|M.gilvum_PYR-GCK MRFPPRLLGPDDS----KRAVHGSVMYAVATGWLYGARTVLAVPTAASTL
Mvan_6058|M.vanbaalenii_PYR-1 MRFPPRLLGPDDS----ARAVHGSVLYAVATGWLHGARTVLAVPSVSSTL
MSMEG_6922|M.smegmatis_MC2_155 VRFGPHVLGPHES----KRAIHGSVAYAVSTGWLHGARTVASVRTVAATL
MAB_4929|M.abscessus_ATCC_1997 SGFPGDRLGPDDS----VRAVHGSAFYAVATGWLHGARTIVGTPSVFDAL
TH_1317|M.thermoresistible__bu ALGAGAVLGALTLSAWQSAFRQNTLLALAAVGFAAATAVAVLVPDVVVVL
**. :.. . .*: .. . . *
Mb0038c|M.bovis_AF2122/97 SGLAAHRMVVGINSLLILLLVRHVTARAVGG---------------LGTA
Rv0037c|M.tuberculosis_H37Rv SGLAAHRMVVGINSLLILLLVRHVTARAVGG---------------LGTA
MMAR_0052|M.marinum_M SGLAAHRMVVGVNSLLILLLVHHMRDVDVEG---------------LGTA
MUL_0051|M.ulcerans_Agy99 SGLAAHRMVVGVNSLLILLLVHHMRDVDVEG---------------LGTA
MAV_0051|M.avium_104 SGLAAHRMVVGINSLLVLLLVHHLPGLEGGG---------------FGTA
Mflv_0849|M.gilvum_PYR-GCK AGLAAHRMVFGINTLLMLVIVRHTETATVAG---------------FGTT
Mvan_6058|M.vanbaalenii_PYR-1 SGLAAHRMVFGVNTLLVLVMVRHTEAATVAG---------------FGTT
MSMEG_6922|M.smegmatis_MC2_155 GGLAAHRAAFGINTLIVLVLVRHTDTPTQVAG------------VGLGTA
MAB_4929|M.abscessus_ATCC_1997 IGLAAHRMVFGVNTLLVLVLVRSNES-VFAG---------------IGAA
TH_1317|M.thermoresistible__bu IGLTVGGMSWLLALATLNASMQLSLPAWVRARGLSVYLLIFMGGQALGST
**:. : : :: . :*::
Mb0038c|M.bovis_AF2122/97 LLFFAATGLGAFLANVLTPTAIRR------WGRYATANGALAAAATIQVA
Rv0037c|M.tuberculosis_H37Rv LLFFAATGLGAFLANVLTPTAIRR------WGRYATANGALAAAATIQVA
MMAR_0052|M.marinum_M LLFFAATGLGAFLANVLTPGLIRR------WGRYATTNGALAAAAVIQLA
MUL_0051|M.ulcerans_Agy99 LLFFAATGLGAFLANVLTPGLIRR------WGRYATTNGALAAAAVTQLA
MAV_0051|M.avium_104 LLFFGAAGLGAFLANVLTPPAIRR------WGRYATANGALAASAIIEVA
Mflv_0849|M.gilvum_PYR-GCK VLFVIAGGAGQFVATIATPALVTR------WGRYAAPNGALALAAVVQVC
Mvan_6058|M.vanbaalenii_PYR-1 VLFVSAGGAGQFLATVVTPTLVKK------WGRYATPNGALAFAAAVQLC
MSMEG_6922|M.smegmatis_MC2_155 VVFVGATGAGTFLATLVMPAVVAR------FGRYATANGALAFAALVQAV
MAB_4929|M.abscessus_ATCC_1997 ALFLACTGIGSFLGTVSTPALLRR------FGRGRTLGMALGGAVVLQLI
TH_1317|M.thermoresistible__bu MWGLVAGSTSTVVAMLISAGLLVVSGLSAWWWPLHPQTGQLDVSPSAHWP
. . . . .:. : . : : . * : .
Mb0038c|M.bovis_AF2122/97 AAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDAL
Rv0037c|M.tuberculosis_H37Rv AAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDAL
MMAR_0052|M.marinum_M GAGLLLPVMVVCGFLLGVAGQVVKLCADSAMQIDVDDALRGHVFAVQDAL
MUL_0051|M.ulcerans_Agy99 GAGLLLPVMVVCGFLLGVAGQVVKLCADSAMQIDVDGALRGHVFAVQDAL
MAV_0051|M.avium_104 GAELLLPVMVVCGFLLGVTGQMVKLCADSAMQMDVDDALRGHVFAVQDAL
Mflv_0849|M.gilvum_PYR-GCK AATLQLPVMIVCGFVLGAAGQVVKLCADSAMQIDVDDALRGHMFAVQDSL
Mvan_6058|M.vanbaalenii_PYR-1 GATLNLPVMIVCGFLLGAAGQVVKLCADTAMQIDVEDALRGHLFAVQDAL
MSMEG_6922|M.smegmatis_MC2_155 ALSLHLPVMLVCGFLLGAAGQFVKLCADSAMQIDVDDALRGHVFTVQDAL
MAB_4929|M.abscessus_ATCC_1997 ASGLYIPILLASAFGLGMAGQVIKLCADVGMQTDVDDALRGHVFAVQDSL
TH_1317|M.thermoresistible__bu EPALVFEPEPRDGPVLVLSTYRVAPEDEPAFLVAMQRQARSRQRTGAALW
* . . * : : : .: :: *.: :
Mb0038c|M.bovis_AF2122/97 FWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTI--------
Rv0037c|M.tuberculosis_H37Rv FWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTI--------
MMAR_0052|M.marinum_M FWVSYIVSVTVAAALIPDDGRAPVFVLVGSVIYLIGLCVHSI--------
MUL_0051|M.ulcerans_Agy99 FWVSYIVSVTVAAALIPDDGRAPVFVLVGSLIYLLGLCVHSI--------
MAV_0051|M.avium_104 FWVAFIVAITVAGMVIPDDGHAPVFALFGSVLYLVGLAVHGI--------
Mflv_0849|M.gilvum_PYR-GCK FWVAFIVAITGAAAVIPADGHSPALAVAGTGLYLAGLAAHAV--------
Mvan_6058|M.vanbaalenii_PYR-1 FWLAFIVAISAAAFVIPPDGRSVGLAVAGVGTYLAGLAVHAT--------
MSMEG_6922|M.smegmatis_MC2_155 FWMSFVCAIAVAALVIAPDGHSPGLVAAGSVIYLAGLGLHAF--------
MAB_4929|M.abscessus_ATCC_1997 FWVTFTGAMAVGAAFIT---HAHWLAFSGAMIYLAGLIVHMTRTLWPSTL
TH_1317|M.thermoresistible__bu RLYRHLEREHTFVEAFLVRSWDEHLRQHHVRLTLVDQRVEEEVR------
. : : * . .
Mb0038c|M.bovis_AF2122/97 ----------VGRR--GQPVIGR---------
Rv0037c|M.tuberculosis_H37Rv ----------VGRR--GQPVIGR---------
MMAR_0052|M.marinum_M ----------VGRRSSAANVEGG---------
MUL_0051|M.ulcerans_Agy99 ----------VGRRSSASNVEGC---------
MAV_0051|M.avium_104 ----------VGRR--GE--------------
Mflv_0849|M.gilvum_PYR-GCK ----------MGRRGR-RG-------------
Mvan_6058|M.vanbaalenii_PYR-1 ----------VGRRGRPRG-------------
MSMEG_6922|M.smegmatis_MC2_155 ----------VASPRRA---------------
MAB_4929|M.abscessus_ATCC_1997 DTGSLPTQPNAGSLPTQPNPEGQARDLDR---
TH_1317|M.thermoresistible__bu -------RYAEGPPLVEHLIAVNFDEITRRGV
.