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MTDEMDRAYLRRPVGDPAPLPADRSLAVLIVIENGHDPVQSCLHSVAEQLPGLPVYVYDNNAQGYPGRQE LAAGHPAVHWISGPADVGFAAACNALARQSPGDSDLLLLKADARLRGPLTRTRQLLRQPGVAAVSPLVRD EAAPDRPPWDIATQRLTLVRGVVEATGLSSSLRATPISPLYPQRPRESQSFSGYLKATCLAISRAAWNAV GGFDEEYFSHGAPADWQARARAAGWRVLLADELGAQQGGAPPTGAETGPTVTAGERRRTRDVIRANDALL LEHQCSVHHADAYLATTKVLQRLRRAQRRAIRNTDAGKRRPAIVIATNRLVYGGAERQKALLAAELDRRG YPVTIVCVQRFGPLIKEIPDTVRVVRQPWWAPIVDVGPGPAVLISGDTNTETGFATLWRAAGRRRRWLVA AHIPPLEDGPIYSRPLTAAMRRADGFIVLAQLHWDMLTPYHRLGGPRFVAPNGVAVTDRPAGRSRPAGAP PHLVMLSRIVEHKNPHQLIEALSGITELPWTLSIFGDGPDRERLQARTPERLRDRVHWRGWSPGPGPALA DADLLCVPSRSEAFPLVILEAMARAVPVAASAICAVPEMLDFGGAGFVVEPVTVSAWQERLAQILADPGG LPAVGQRGFARMRKHYTVAAMTDAYLDAIHAVL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4676 | - | - | 100% (663) | glycosyltransferase |
| M. ulcerans Agy99 | MUL_2611 | wbbL1 | 4e-10 | 29.29% (198) | dTDP-rha:A-D-GlcNAc-diphosphoryl polyprenol A-3- |
| M. ulcerans Agy99 | MUL_1919 | - | 1e-08 | 29.18% (233) | transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3293c | wbbL1 | 3e-10 | 28.43% (204) | dTDP-RHA:A-D-GlcNAc-diphosphoryl polyprenol |
| M. gilvum PYR-GCK | Mflv_1501 | - | 5e-09 | 26.78% (183) | glycosyl transferase, group 1 |
| M. tuberculosis H37Rv | Rv3265c | wbbL1 | 4e-10 | 28.43% (204) | dTDP-RHA:A-D-GlcNAc-diphosphoryl polyprenol |
| M. leprae Br4923 | MLBr_00752 | wbbL | 3e-09 | 35.45% (110) | putative dTDP-rhamnosyl transferase |
| M. abscessus ATCC 19977 | MAB_3612c | - | 4e-13 | 30.40% (227) | putative dTDP-rhamnosyltransferase |
| M. marinum M | MMAR_4505 | - | 0.0 | 96.53% (663) | glycosyltransferase |
| M. avium 104 | MAV_4230 | - | 2e-11 | 29.82% (218) | dTDP-RhA:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl |
| M. smegmatis MC2 155 | MSMEG_1826 | - | 4e-12 | 26.75% (228) | dTDP-RhA:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl |
| M. thermoresistible (build 8) | TH_0780 | wbbL | 6e-10 | 26.09% (207) | PROBABLE dTDP-RHA:A-D-GlcNAc-DIPHOSPHORYL POLYPRENOL, |
| M. vanbaalenii PYR-1 | Mvan_5245 | - | 1e-08 | 25.86% (232) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4676|M.ulcerans_Agy99 MTDEMDRAYLRRPVGDPAPLPADRSLAVLIVIENGHDPVQSCLHSVAEQL
MMAR_4505|M.marinum_M MTEEMDRAYLQRPVGDLAPLPAERSLAVLIVIGNGHDPVQSCLHSVAEQL
Mb3293c|M.bovis_AF2122/97 ---------------------------MVAVTYSPGPHLERFLASLSLAT
Rv3265c|M.tuberculosis_H37Rv ---------------------------MVAVTYSPGPHLERFLASLSLAT
MLBr_00752|M.leprae_Br4923 ---------------------MTDVLPVVAVTYSPGPHLERFLASLALAT
MAV_4230|M.avium_104 ------------------------MLPVVTVTYSPGPHLERFLASLSLAT
MSMEG_1826|M.smegmatis_MC2_155 --------------------------MVVTVTYSPGPHLDRFLSSLSLAT
TH_0780|M.thermoresistible__bu ---------------------VSDHLVVVTVTYSPGPHLERFLASLEHAT
MAB_3612c|M.abscessus_ATCC_199 ----------MLDPHRVSDSPAIGQVAVVTVTYSPGEHLHRFLRTLRHAT
Mflv_1501|M.gilvum_PYR-GCK ----------------------MNRRHVTYLVSRFPVTSETFIVRELEAL
Mvan_5245|M.vanbaalenii_PYR-1 ----------------------MSRRDVVYLVSRFPVTSETFIVREIEAL
: : . :
MUL_4676|M.ulcerans_Agy99 PGLPVYVYDNNAQGYPGRQELAAGHPAVHWISGPADVGFAAACN-ALARQ
MMAR_4505|M.marinum_M PGLPVYVYDNSGQGYPGRQELAAGHPAVHWISGPADVGFAAACN-ALAQR
Mb3293c|M.bovis_AF2122/97 ERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQL
Rv3265c|M.tuberculosis_H37Rv ERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQL
MLBr_00752|M.leprae_Br4923 DRPVSVVLADNGSTDGTPQVAVERYVNVRLFETGANLGYGTAANLAIAQF
MAV_4230|M.avium_104 EREVCVLLADNGSTDGTPQAAVERYPNVRLFHTGANLGYGTAVNRAVAQL
MSMEG_1826|M.smegmatis_MC2_155 DRPVTVIMADNGSTDGTPEEAEQRYPNVRLLRTGANLGYGSAVNRAVAQL
TH_0780|M.thermoresistible__bu ERPVTVIMADNGSTDGAPEEALERYPNVRLMRTGANLGYGTAINRAVAEH
MAB_3612c|M.abscessus_ATCC_199 DLPLRVILADNGSTDGAPEAAAEE-PDVELLRTGGNVGYGKAANLGVAQV
Mflv_1501|M.gilvum_PYR-GCK DRSGEFELEIR-SLFPSPDRAVHEIARRWNEHLVRPSAFDAAAGVTWALL
Mvan_5245|M.vanbaalenii_PYR-1 DRSGKFHVEIR-SLFPSPDEPVHDIARRWSRHLVRPTARDAATGLAWALL
. : . * . *
MUL_4676|M.ulcerans_Agy99 SPGDS--------DLLLLKADARLRGP---LTRTRQLLRQPGVAAVSPLV
MMAR_4505|M.marinum_M SPGDS--------DLLLLKADARLRGP---LTRTRQLLRQPGVAAVSPLV
Mb3293c|M.bovis_AF2122/97 GEMAGDAGEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLI
Rv3265c|M.tuberculosis_H37Rv GEMAGDAGEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLI
MLBr_00752|M.leprae_Br4923 FEEGGATGQPWVDDWVIVANPDVQWGPGSIDALLDAAARWPRAGALGPLI
MAV_4230|M.avium_104 DR-GG--------EWVIVANPDVQWGPGSIDALLDAAARWPRAGALGPLV
MSMEG_1826|M.smegmatis_MC2_155 TAGEG-------TDFLVVANPDVQWGPKAIDLLLEASDRWPHAGAFGPLI
TH_0780|M.thermoresistible__bu LADTDP------SDFFVVANPDVQWGPNSIDNLLAAAARWPRAAALGPLI
MAB_3612c|M.abscessus_ATCC_199 DP---------AAEWVVIANPDVQWGPGSIDAMLEVAQRWPAAGAVGPLI
Mflv_1501|M.gilvum_PYR-GCK TRPIALMT-----ILANVVAGYRRRLPLLVRALMTVPLACAHARDLARRA
Mvan_5245|M.vanbaalenii_PYR-1 TRPIAVMS-----VLATVTSGYLRRPPLLVRALTTVPIACAHARDLARRG
: * . . ..
MUL_4676|M.ulcerans_Agy99 RDEAAPDRPPWDIATQRLTLVRGVVEATGLSSSLRATPISPLYPQR-PRE
MMAR_4505|M.marinum_M RDEAAPDRPPWDIATQRLTLVRGVVEATGLSSWLRATRISPLYPQR-PRE
Mb3293c|M.bovis_AF2122/97 RD---PDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQER-LEP
Rv3265c|M.tuberculosis_H37Rv RD---PDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQER-LEP
MLBr_00752|M.leprae_Br4923 RD---PDGSVYPSARHLPSLVRGGMHAVLGPVWPRNPWTAAYRQER-LEL
MAV_4230|M.avium_104 RD---PDGSVYPSARHLPSLVRGGMHAVVGPFWKNNPWSTAYRQER-LEP
MSMEG_1826|M.smegmatis_MC2_155 RD---PDGAIYPSARHQPSLLRGGLHAVVGPFWKNNPWTAAYRQDR-QEP
TH_0780|M.thermoresistible__bu RD---ADGSVYPSAREQPSLIRGGMHAVIGPLWPGNPWTAAYRQDR-MEP
MAB_3612c|M.abscessus_ATCC_199 RE---PDGTVYPSARVVPTLTGGALHALLGSVWSTNPWTAAYRQDR-MEP
Mflv_1501|M.gilvum_PYR-GCK QP-----CHVHAHYATYPALAAWVCHRLAGTSYSFTVHAHDLYVDTSMLD
Mvan_5245|M.vanbaalenii_PYR-1 RP-----CHVHAHYATYPALAAWVCRRLAGISYSFTVHAHDLYVDMSMLD
: :* . :
MUL_4676|M.ulcerans_Agy99 SQSFSGYLKATCLAISRAAWNAVGGFDEEYFSHGAPADWQ-----ARARA
MMAR_4505|M.marinum_M SQSVSGYLKATCLAISRAAWNAIGGFDEEYLNHGGPADWQ-----ARARA
Mb3293c|M.bovis_AF2122/97 SERPVGWLSGSCLLVRRSAFGQVGGFDERYFMYMEDVDLG-----DRLGK
Rv3265c|M.tuberculosis_H37Rv SERPVGWLSGSCLLVRRSAFGQVGGFDERYFMYMEDVDLG-----DRLGK
MLBr_00752|M.leprae_Br4923 TERPVGWLSGSCLLVRRSAFREVGGFDERYFMYMEDVDLG-----DRLGK
MAV_4230|M.avium_104 SERPVGWLSGSCLLVRRSAFERVGGFDERYFMYMEDVDLG-----DRLGK
MSMEG_1826|M.smegmatis_MC2_155 SERPVGWLSGSCLLLRRNAFDAIGGFDERYFMYMEDVDLG-----DRLDR
TH_0780|M.thermoresistible__bu TERPVGWLSGSCLLLRKAAFDEVDGFDERYFMYMEDVDLG-----DRLAK
MAB_3612c|M.abscessus_ATCC_199 SERVVGWLSGSCLLLRRTAFDAIGGFDPRYFMYMEDVDLG-----DRLAR
Mflv_1501|M.gilvum_PYR-GCK RKIAEARYVVTISHYNRALLERHNPAGIPVRVVHAGIDTGRYHFRPRGIP
Mvan_5245|M.vanbaalenii_PYR-1 RKIADACYVVTISQYNRALLEQHNSMGTPIRVVHAGIDVGAYRFRARGVP
: . : : . . * *
MUL_4676|M.ulcerans_Agy99 AGWRVLLADELGAQQGGAPPTGAETGPTVTAGERRRTRDVIRANDALLLE
MMAR_4505|M.marinum_M AGWRVLLADELGAQQGGAPPTGAETGPTVTAGERRRTRDVIRANDALLLE
Mb3293c|M.bovis_AF2122/97 AGWLSVYVPSAEVLHHKAHSTGRDP-----------------------AS
Rv3265c|M.tuberculosis_H37Rv AGWLSVYVPSAEVLHHKAHSTGRDP-----------------------AS
MLBr_00752|M.leprae_Br4923 AGWLSVYVPSAEVLHHKGHSTGRDP-----------------------VS
MAV_4230|M.avium_104 AGWLSVYVPSAEVLHHKGHSTGADP-----------------------AS
MSMEG_1826|M.smegmatis_MC2_155 AGWQNIYVPSAEVLHYKGHSTGRDP-----------------------AR
TH_0780|M.thermoresistible__bu AGWQNIYVPSSEILHYKGHAAGRDP-----------------------AR
MAB_3612c|M.abscessus_ATCC_199 AGWQNVYAPSSEVVHAKGHAAGRDP-----------------------AR
Mflv_1501|M.gilvum_PYR-GCK TEGPVRALTVASLQQYKGHAVLLEALAIGGPA----------------VE
Mvan_5245|M.vanbaalenii_PYR-1 AEGEVRALTVASLQQYKGHAVLLEALAMGGPE----------------VD
: : . .. :.
MUL_4676|M.ulcerans_Agy99 HQCSVHHADAYLATTKVLQRLRRAQRRAIRNT---DAGKRRPAIVIATNR
MMAR_4505|M.marinum_M HQCSVHHADAYLATTKVLQRLRRAQRRAIRNT---GAGKRRPAIVIATNR
Mb3293c|M.bovis_AF2122/97 HLAAHHKSTYIFLADRHSGWWRAPLRWTLR-----GSLALRSHLMVR---
Rv3265c|M.tuberculosis_H37Rv HLAAHHKSTYIFLADRHSGWWRAPLRWTLR-----GSLALRSHLMVRSSL
MLBr_00752|M.leprae_Br4923 HLAAHHKSTYIFLADRHSGWWRAPLRWMLR-----GSLVVRSRLMVRSSR
MAV_4230|M.avium_104 HLAAHHRSTYMFLADRYSGWMRAPLRWALR-----ASLAVRARLMVR---
MSMEG_1826|M.smegmatis_MC2_155 NLAAHHRSTYTFLADRYPATWQAPLRWAIR-----GALAVRAGLVVG---
TH_0780|M.thermoresistible__bu NLVAHHRSTYTFLADRYPRWWQSPLRWTIR-----GALAVRANLAVG---
MAB_3612c|M.abscessus_ATCC_199 SLGAHHDSVYIFQSDRHPHWWQAPLRWSIR-----GALAARSAIVVR---
Mflv_1501|M.gilvum_PYR-GCK RITLDLIGDGVLRPHLEALVERWGLRERVRFRGSCSEDVVRAALDAADLF
Mvan_5245|M.vanbaalenii_PYR-1 RITLDLIGDGVLRGDLEALVDRLGLRDRVRFLGSCSEEAVRAALDAADLF
. : : * :* *. :
MUL_4676|M.ulcerans_Agy99 LVYGGAERQKALLAAELDRRGYPVTIVCVQRFGPLIKEIPDTVRVVRQPW
MMAR_4505|M.marinum_M LVYGGAERQKALLAAELDRRGYPVTIVCVQRFGPLIKEIPDTVRVVRQPW
Mb3293c|M.bovis_AF2122/97 --RSRRRKLKLVEGRH----------------------------------
Rv3265c|M.tuberculosis_H37Rv R-RSRRRKLKLVEGRH----------------------------------
MLBr_00752|M.leprae_Br4923 RKQAAKQARQLAEGRR----------------------------------
MAV_4230|M.avium_104 --SALRESGRRVEGRH----------------------------------
MSMEG_1826|M.smegmatis_MC2_155 --NSRRK--RANKG----------------AW------------------
TH_0780|M.thermoresistible__bu --NSRRKQARVRPGEERPARNPARNTDMGTTW------------------
MAB_3612c|M.abscessus_ATCC_199 --AAIRANRRRDKQGG----------------------------------
Mflv_1501|M.gilvum_PYR-GCK VLPSLVADDGQMEGLPVVLMEALACGVPTVATDLSG--------------
Mvan_5245|M.vanbaalenii_PYR-1 VLPSIVADDGQMEGLPVALMEALACGVPAVSTKLSG--------------
.
MUL_4676|M.ulcerans_Agy99 WAPIVDVGPGPAVLISGDTNTETGFATLWRAAGRRRRWLVAAHIPPLEDG
MMAR_4505|M.marinum_M WAPIVDVGPGPAVLISGDTNTETGFATLWRAAGRRRRWLVAAHIPPLEVG
Mb3293c|M.bovis_AF2122/97 --------------------------------------------------
Rv3265c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00752|M.leprae_Br4923 --------------------------------------------------
MAV_4230|M.avium_104 --------------------------------------------------
MSMEG_1826|M.smegmatis_MC2_155 --------------------------------------------------
TH_0780|M.thermoresistible__bu --------------------------------------------------
MAB_3612c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1501|M.gilvum_PYR-GCK IPEIVVDGVTGLLAQPGDAASLNRALTAMIERGGDAEVFTGPGRELVTRE
Mvan_5245|M.vanbaalenii_PYR-1 IPEIVVDGVTGLLATPGDAASLNATLTAMVQRGTAAVEFADAGRALVSRE
MUL_4676|M.ulcerans_Agy99 PIYSRPLTAAMRRADGFIVLAQLHWDMLTPYHRLGGPRFVAPNGVAVTDR
MMAR_4505|M.marinum_M PIYSGPLTAAMRRADGFIVLAQRHWDMLTPYHRLGGPRFVAPNGVAVTDR
Mb3293c|M.bovis_AF2122/97 --------------------------------------------------
Rv3265c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00752|M.leprae_Br4923 --------------------------------------------------
MAV_4230|M.avium_104 --------------------------------------------------
MSMEG_1826|M.smegmatis_MC2_155 --------------------------------------------------
TH_0780|M.thermoresistible__bu --------------------------------------------------
MAB_3612c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1501|M.gilvum_PYR-GCK FDLRESIDALTGLLDEYVPALPAQR-------------------------
Mvan_5245|M.vanbaalenii_PYR-1 FDLRESIAALTGLLDEYLPPVAS---------------------------
MUL_4676|M.ulcerans_Agy99 PAGRSRPAGAPPHLVMLSRIVEHKNPHQLIEALSGITELPWTLSIFGDGP
MMAR_4505|M.marinum_M PAGRSRPAGAPPHLVMLSRIVEHKNPHLLIEALSGITELPWTLSIFGDGP
Mb3293c|M.bovis_AF2122/97 --------------------------------------------------
Rv3265c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00752|M.leprae_Br4923 --------------------------------------------------
MAV_4230|M.avium_104 --------------------------------------------------
MSMEG_1826|M.smegmatis_MC2_155 --------------------------------------------------
TH_0780|M.thermoresistible__bu --------------------------------------------------
MAB_3612c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1501|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5245|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4676|M.ulcerans_Agy99 DRERLQARTPERLRDRVHWRGWSPGPGPALADADLLCVPSRSEAFPLVIL
MMAR_4505|M.marinum_M DRERLQARTPERLRDRVHWRGWSPGPGPALADADLLCVPSRSEAFPLVIL
Mb3293c|M.bovis_AF2122/97 --------------------------------------------------
Rv3265c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00752|M.leprae_Br4923 --------------------------------------------------
MAV_4230|M.avium_104 --------------------------------------------------
MSMEG_1826|M.smegmatis_MC2_155 --------------------------------------------------
TH_0780|M.thermoresistible__bu --------------------------------------------------
MAB_3612c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1501|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5245|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4676|M.ulcerans_Agy99 EAMARAVPVAASAICAVPEMLDFGGAGFVVEPVTVSAWQERLAQILADPG
MMAR_4505|M.marinum_M EAMARAVPVAASAICAVPEMLDFGGAGFVVEPVTVSAWRERLAQILADPG
Mb3293c|M.bovis_AF2122/97 --------------------------------------------------
Rv3265c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00752|M.leprae_Br4923 --------------------------------------------------
MAV_4230|M.avium_104 --------------------------------------------------
MSMEG_1826|M.smegmatis_MC2_155 --------------------------------------------------
TH_0780|M.thermoresistible__bu --------------------------------------------------
MAB_3612c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1501|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5245|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4676|M.ulcerans_Agy99 GLPAVGQRGFARMRKHYTVAAMTDAYLDAIHAVL
MMAR_4505|M.marinum_M ELPAVGQRGFARMRKHYTVAAMTDAYLDAIHAVL
Mb3293c|M.bovis_AF2122/97 ----------------------------------
Rv3265c|M.tuberculosis_H37Rv ----------------------------------
MLBr_00752|M.leprae_Br4923 ----------------------------------
MAV_4230|M.avium_104 ----------------------------------
MSMEG_1826|M.smegmatis_MC2_155 ----------------------------------
TH_0780|M.thermoresistible__bu ----------------------------------
MAB_3612c|M.abscessus_ATCC_199 ----------------------------------
Mflv_1501|M.gilvum_PYR-GCK ----------------------------------
Mvan_5245|M.vanbaalenii_PYR-1 ----------------------------------