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M. ulcerans Agy99 MUL_4434 (-)

annotation: ATP-dependent DNA ligase
coordinates: 4917308 - 4919620
length: 770

GSAQAWPPGQANGPQVTLTNADKVLYPATGTTKSDVFGYYTGIAEVMIPHIAGRPATRKRWPNGVDQASF
FEKQLASSAPDWLPRASVVHRSGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTSKGEILTPGPA
TRLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHFYTPLDEPVSSKGATVLAKRVAQ
QLETVMPALVTATMTKSLRAGKVFLDWSQNSGSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYD
EVLARLTRDGDLIAALDADLPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTFVIQEHHARRLHDDFR
LERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLEYATFEGNIPKGEYGAGKVIIWDSGTYDTEKFRDDS
RNGAEKGEVIVNLHGSRISGRYALIQTNGDQWLAHRMKDQTAFDFDTLAPMLTSHGSVAGLESGQWAFEG
KWDGYRLLVEADHGALRLRSRSGRDVTTEYPQLRSLAADLADHHVVLDGELVALDSSGVPSFNEMQNRVR
ATRIEFWAFDLLFLDGRSLLRARYRDRRKLLETLGSAGNLIVPELLPGDGAEALAYSHKRGWEGVIAKRR
DSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGSLLMGIPGPSGLHFAGRVGTGFTERDLAN
LKKTLAPLHTDESPFDAALPAREAKGVTFVVPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4434--100% (770)ATP-dependent DNA ligase
M. ulcerans Agy99MUL_1190-2e-3832.67% (300) hypothetical protein MUL_1190
M. ulcerans Agy99MUL_4339-2e-2628.18% (291) hypothetical protein MUL_4339

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0963-0.081.28% (764) ATP-dependent DNA ligase
M. gilvum PYR-GCKMflv_1828-0.072.49% (756) ATP-dependent DNA ligase
M. tuberculosis H37RvRv0938-0.081.15% (764) ATP-dependent DNA ligase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1033-0.069.10% (754) ATP-dependent DNA ligase
M. marinum MMMAR_4573-0.099.35% (770) ATP dependent DNA ligase
M. avium 104MAV_1056-0.081.14% (774) ATP-dependent DNA ligase
M. smegmatis MC2 155MSMEG_5570-0.069.86% (763) ATP-dependent DNA ligase
M. thermoresistible (build 8)TH_3391-0.071.37% (758) PUTATIVE ATP dependent DNA ligase
M. vanbaalenii PYR-1Mvan_4915-0.073.07% (765) ATP-dependent DNA ligase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1828|M.gilvum_PYR-GCK          MVDRYDR------------VKLTNPDKVLYPASG-----TTKAQVFEYYV
Mvan_4915|M.vanbaalenii_PYR-1       MVDRYER------------VKLTNPDKVLYPATGDRRRAVTKAEVFDYYV
MSMEG_5570|M.smegmatis_MC2_155      -MERYER------------VRLTNPDKVLYPATG-----TTKAEVFDYYL
TH_3391|M.thermoresistible__bu      -MERYER------------VKLTNPDKVLYPASG-----TTKAEVFEYYI
MUL_4434|M.ulcerans_Agy99           ---MGSAQAWPPGQANGPQVTLTNADKVLYPATG-----TTKSDVFGYYT
MMAR_4573|M.marinum_M               ---MGSAQAWPPGQANGPQVTLTNADKVLYPATG-----TTKSDVFGYYT
Mb0963|M.bovis_AF2122/97            ---MGSASEQ--------RVTLTNADKVLYPATG-----TTKSDIFDYYA
Rv0938|M.tuberculosis_H37Rv         ---MGSASEQ--------RVTLTNADKVLYPATG-----TTKSDIFDYYA
MAV_1056|M.avium_104                ---MNAPRAWPAEPTATPRVKLTNADKVLYPATG-----TTKADVFDYYT
MAB_1033|M.abscessus_ATCC_1997      ---------------------------MLYPATDTSP-ATTKADVFGYYT
                                                               :****:.     .**:::* ** 

Mflv_1828|M.gilvum_PYR-GCK          NVAEGMLPHIAGRAVTRKRWPNGVEESSFFEKQLASSAPDWLDRGTIAHK
Mvan_4915|M.vanbaalenii_PYR-1       NVAAAMLPHIAGRAVTRKRWPNGVTEESFFEKQLASSAPDWLGRGTIVHK
MSMEG_5570|M.smegmatis_MC2_155      SIAQVMVPHIAGRPVTRKRWPNGVAEEAFFEKQLASSAPSWLERGSITHK
TH_3391|M.thermoresistible__bu      EIADAMLPHIAGRPVTRKRWPNGVHEASFFEKQLASSAPDWLARGTITHK
MUL_4434|M.ulcerans_Agy99           GIAEVMIPHIAGRPATRKRWPNGVDQASFFEKQLASSAPDWLPRASVVHR
MMAR_4573|M.marinum_M               GIAEVMIPHIAGRPATRKRWPNGVDQASFFEKQLASSAPDWLPRASVVHR
Mb0963|M.bovis_AF2122/97            GVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHR
Rv0938|M.tuberculosis_H37Rv         GVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHR
MAV_1056|M.avium_104                RIADVMIPHIAGRPVTRKRWPNGVDQESFFEKQLASSAPDWLPRASVTHR
MAB_1033|M.abscessus_ATCC_1997      AIAPFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSAPDWLPRRRIEHK
                                     :*  *: *****..********: : :****:** *** ** *  : *:

Mflv_1828|M.gilvum_PYR-GCK          SGTTTYPVIDTVEGLAWIAQQAALEVHVPQWRFTRGGQSGAADGGDGKPG
Mvan_4915|M.vanbaalenii_PYR-1       SGTTTYPVIDTVEGLAWIAQQAALEVHVPQWRFV-----------DGSVG
MSMEG_5570|M.smegmatis_MC2_155      SGTTTYPIINTREGLAWVAQQASLEVHVPQWRFEDGDQ-----------G
TH_3391|M.thermoresistible__bu      SRTTTYPIIDTREGLAWIAQQAALEVHVPQWRFVAGGRSGR--DGKLTMG
MUL_4434|M.ulcerans_Agy99           SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWT---SKGEILTPG
MMAR_4573|M.marinum_M               SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWT---SKGEILTPG
Mb0963|M.bovis_AF2122/97            SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPG---SGE--LNPG
Rv0938|M.tuberculosis_H37Rv         SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPG---SGE--LNPG
MAV_1056|M.avium_104                SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTR--SRAEELKPG
MAB_1033|M.abscessus_ATCC_1997      SRYVSYPLIDTSVALAWIAQQAALEVHVPQWRFAGENP-----------G
                                    *  .:**:*::  .***:****:**********                *

Mflv_1828|M.gilvum_PYR-GCK          PATRIVFDLDPGEGVTFRQLCEVAHEVRELITDIGLTTFPLTSGSKGLHL
Mvan_4915|M.vanbaalenii_PYR-1       PATRIVFDLDPGEGVTFRQLCEVANEVRDLLADIGLRTFPLTSGSKGLHL
MSMEG_5570|M.smegmatis_MC2_155      PATRIVFDLDPGEGVTMTQLCEIAHEVRALMTDLDLETYPLTSGSKGLHL
TH_3391|M.thermoresistible__bu      PATRIVFDLDPGEGVTMRELCRVAHEVRDLITDIGLDTFPLTSGSKGLHL
MUL_4434|M.ulcerans_Agy99           PATRLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHF
MMAR_4573|M.marinum_M               PATRLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHL
Mb0963|M.bovis_AF2122/97            PATRLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHL
Rv0938|M.tuberculosis_H37Rv         PATRLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHL
MAV_1056|M.avium_104                PATRLVFDLDPGEGVTMAQLAEVARAVRDLIDGIGLQTFPLTSGSKGLHL
MAB_1033|M.abscessus_ATCC_1997      PATRLVFDLDPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLHL
                                    ****:********** : :*..:*. :* :: .:.* * *:********:

Mflv_1828|M.gilvum_PYR-GCK          YVPLEDPISSRGASVLAKRVAQQLEQSMPKRVTATMTKSLRDGKVFLDWS
Mvan_4915|M.vanbaalenii_PYR-1       YVPLDEPISSRGASVLAKRVAQQLEQAMPMQVTATMTKSLRTGKVFVDWS
MSMEG_5570|M.smegmatis_MC2_155      YVPLAEPISSRGASVLARRVAQQLEQAMPKLVTATMTKSLRAGKVFLDWS
TH_3391|M.thermoresistible__bu      YVPLDEPISSQGASVLAKRVALQLEKAMPTLVTATMTKSVRTGKVFLDWS
MUL_4434|M.ulcerans_Agy99           YTPLDEPVSSKGATVLAKRVAQQLETVMPALVTATMTKSLRAGKVFLDWS
MMAR_4573|M.marinum_M               YTPLDEPVSSKGATVLAKRVAQQLETVMPALVTATMTKSLRAGKVFLDWS
Mb0963|M.bovis_AF2122/97            YTPLDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWS
Rv0938|M.tuberculosis_H37Rv         YTPLDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWS
MAV_1056|M.avium_104                YTPLTEPVSSKGATVLAKRVAQQLEKTMPKLVTSTMTKSLRAGKIFVDWS
MAB_1033|M.abscessus_ATCC_1997      YVPLAQPASSSGAVAVAKKVAVQLEQVMPDLVTATMTRQLRAGKVFVDWS
                                    *.** :* ** ** .:*::** :**  **  **:***:.:* **:*:***

Mflv_1828|M.gilvum_PYR-GCK          QNNGNKTTIAPYSLRGRERPTVAAPRTWDEIEDPDLRHLTFDEVLDRLER
Mvan_4915|M.vanbaalenii_PYR-1       QNNANKTTIAPYSLRGREHPTVAAPRTWEEISDPDLRQLTFDEVLDRLDR
MSMEG_5570|M.smegmatis_MC2_155      QNNAAKTTIAPYSLRGRDHPTVAAPRTWDEIADPELRHLRFDEVLDRLDE
TH_3391|M.thermoresistible__bu      QNNAAKTTIAPYSLRGREHPTVAAPRTWDEIDDPDLRHLTFTEVLDRVDR
MUL_4434|M.ulcerans_Agy99           QNSGSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYDEVLARLTR
MMAR_4573|M.marinum_M               QNSGSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYDEVLARLTR
Mb0963|M.bovis_AF2122/97            QNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIAR
Rv0938|M.tuberculosis_H37Rv         QNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIAR
MAV_1056|M.avium_104                QNNGSKTTIAPYSLRGRDHPTVAAPRTWDELDDPALRHLRYDEVLTRVAR
MAB_1033|M.abscessus_ATCC_1997      QNSGSKTTVAPYSLRGRAVPTVAAPRTWEELDDPGLRQLRYDEVLTRAQR
                                    **.. ***:********  *******:* *: ** **:* : *** *  .

Mflv_1828|M.gilvum_PYR-GCK          DGDLLADLDPP---LPATDKLTRYRSMRDRTKTPEPVPAEPPETGANDKF
Mvan_4915|M.vanbaalenii_PYR-1       DGDLLAGLDPP---VPVPDRLTRYRSMRDTAKTPEPIPGDAPTTGNNDKF
MSMEG_5570|M.smegmatis_MC2_155      YGDLLAPLDAD---APIADKLTTYRSMRDASKTPEPVPKEIPKTGNNDKF
TH_3391|M.thermoresistible__bu      LGDLLAPMDAD---APVADRLSSYRSMRDPARTPEPVPKTVAATGDDNRF
MUL_4434|M.ulcerans_Agy99           DGDLIAALDAD---LPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTF
MMAR_4573|M.marinum_M               DGDLIAALDAD---LPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTF
Mb0963|M.bovis_AF2122/97            DGDLLERLDAD---APVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTF
Rv0938|M.tuberculosis_H37Rv         DGDLLERLDAD---APVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTF
MAV_1056|M.avium_104                DGDLLAELDASDNQTPVPDRLTKYRSMRDASKTPEPVPAAKPAAGRGNTF
MAB_1033|M.abscessus_ATCC_1997      DGDLLAGLDDV---EIAEDRLSTYRSMRDPTRTPEPVPAVKPEAGQDNSF
                                     ***:  :*         *:*  ** **: ::****:*   . .* .: *

Mflv_1828|M.gilvum_PYR-GCK          VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPSVNHLAVHTEDHPMD
Mvan_4915|M.vanbaalenii_PYR-1       VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPSVNHLAVHTEDHPME
MSMEG_5570|M.smegmatis_MC2_155      VIQEHHARRLHYDLRLERDGVLVSFAVPKNLPETTAENRLAVHTEDHPIE
TH_3391|M.thermoresistible__bu      VIQEHHARRLHYDLRLERDGVLVSWAIPKNLPDDPSVNHLAVHTEDHPLE
MUL_4434|M.ulcerans_Agy99           VIQEHHARRLHDDFRLERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLE
MMAR_4573|M.marinum_M               VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLE
Mb0963|M.bovis_AF2122/97            VIQEHHARRPHYDFRLERDGVLVSWAVPKNLPDNTSVNHLAIHTEDHPLE
Rv0938|M.tuberculosis_H37Rv         VIQEHHARRPHYDFRLECDGVLVSWAVPKNLPDNTSVNHLAIHTEDHPLE
MAV_1056|M.avium_104                VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPAVNHLAVHTEDHPLE
MAB_1033|M.abscessus_ATCC_1997      VIQEHHATALHYDFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLE
                                    *******   * *:*** ******:*:*****  .: *:**:******::

Mflv_1828|M.gilvum_PYR-GCK          YIDFAGEIPKGEYGGGEVHIWDTGTYETEKFR---DNPPDGPAKGGEVIV
Mvan_4915|M.vanbaalenii_PYR-1       YLTFAGEIPRGEYGGGEVYIWDTGTYETEKFR---DNPPDGPDRGGEVIV
MSMEG_5570|M.smegmatis_MC2_155      YLAFHGSIPKGEYGAGDMVIWDSGSYETEKFRVP-EELDNPDDSHGEIIV
TH_3391|M.thermoresistible__bu      YLTFHGEIPEGEYGGGKMLIWDTGTYEAEKFN---DVGPDEDAEGGEVII
MUL_4434|M.ulcerans_Agy99           YATFEGNIPKGEYGAGKVIIWDSGTYDTEKFR----DDSRNGAEKGEVIV
MMAR_4573|M.marinum_M               YATFEGNIPKGEYGAGKVIIWDSGTYDTEKFR----DDSRNGSEKGEVIV
Mb0963|M.bovis_AF2122/97            YATFEGAIPSGEYGAGKVIIWDSGTYDTEKFH----DDPHTG----EVIV
Rv0938|M.tuberculosis_H37Rv         YATFEGAIPSGEYGAGKVIIWDSGTYDTEKFH----DDPHTG----EVIV
MAV_1056|M.avium_104                YGGFEGVIPKGEYGAGRVVIWDSGTYDAEKFQ----DD--------EVIV
MAB_1033|M.abscessus_ATCC_1997      YGSFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADGGQKGEVIV
                                    *  * * ** ****.* : ***:*:*::***               *:*:

Mflv_1828|M.gilvum_PYR-GCK          TLHGQKIEGRYALIQTDGKNWLAHRMKDQQ---KPTAADLAPMLTTEGSV
Mvan_4915|M.vanbaalenii_PYR-1       TLHGEKIDGRYALIQTDGKNWLAHRMKDQQ---RPTAADLAPMLTTHGSV
MSMEG_5570|M.smegmatis_MC2_155      TLHGEKVDGRYALIQTKGKNWLAHRMKDQK---NARPEDFAPMLATEGSV
TH_3391|M.thermoresistible__bu      TLHGEKISGRYALIQTDGKNWLAHKMKDQKPRTEIRPEDFTPMLATHGSV
MUL_4434|M.ulcerans_Agy99           NLHGSRISGRYALIQTNGDQWLAHRMK---DQTAFDFDTLAPMLTSHGSV
MMAR_4573|M.marinum_M               NLHGSRISGRYALIQTNGDQWLAHRMK---DQTAFDFDTLAPMLTSHGSV
Mb0963|M.bovis_AF2122/97            NLHGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTV
Rv0938|M.tuberculosis_H37Rv         NLHGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTV
MAV_1056|M.avium_104                NLHGRKISGRYALIQTEGDQWLAHRMK---DQNVFDFDTIAPMLATHGSV
MAB_1033|M.abscessus_ATCC_1997      TLHGKRITGRYALIRTNGKQWLVHRMKDQRPAGSMPVG-LAPMLPTTGSV
                                    .*** :: ******:*.*..**.*::*            ::***.: *:*

Mflv_1828|M.gilvum_PYR-GCK          ERLTRGQWAFEGKWDGYRLLVDADHGKLTLRSRRGRDVTAEYPQLKALAA
Mvan_4915|M.vanbaalenii_PYR-1       QRLTKGQWAFEGKWDGYRLLVEADHGRLALRSRNGRDVTAEYPQLQALAA
MSMEG_5570|M.smegmatis_MC2_155      AKYKAKQWAFEGKWDGYRVIIDADHGQLQIRSRTGREVTGEYPQFKALAA
TH_3391|M.thermoresistible__bu      ARLSAETHAFEGKWDGYRLLVHIDHGKLCLRSRSGRDVTKEFPTLQAMAA
MUL_4434|M.ulcerans_Agy99           AGLESGQWAFEGKWDGYRLLVEADHGALRLRSRSGRDVTTEYPQLRSLAA
MMAR_4573|M.marinum_M               AGLESGQWAFEGKWDGYRLLVEADHGALRLRSRSGRDVTAEYPQLRSLAA
Mb0963|M.bovis_AF2122/97            AGLKASQWAFEGKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAE
Rv0938|M.tuberculosis_H37Rv         AGLKASQWAFEGKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAE
MAV_1056|M.avium_104                SALKASQWAFEGKWDGYRLLVEADHGTLRVRSRRGREVTGEYRELRSLAK
MAB_1033|M.abscessus_ATCC_1997      AGLTAEEWAFEGKWDGYRLILECDRGQLRALARSGRDVTAEFPALQRLAH
                                            **********:::. *:* :   :* **:** *:  :: :* 

Mflv_1828|M.gilvum_PYR-GCK          DLADHHVILDGEAVALDEDGVPSFGEMQNRARSTRVEFWAFDILFLDGRL
Mvan_4915|M.vanbaalenii_PYR-1       DLADHHVILDGEAVALDESGVPSFREMQNRARSTRVEFWAFDILFLDGRS
MSMEG_5570|M.smegmatis_MC2_155      DLAEHHVVLDGEAVALDESGVPSFGQMQNRARSTRVEFWAFDILWLDGRS
TH_3391|M.thermoresistible__bu      DLADHQVVLDGEVVALDGSGVPSFGEMQNRARATHIEFWAFDILWLDGRS
MUL_4434|M.ulcerans_Agy99           DLADHHVVLDGELVALDSSGVPSFNEMQNRVRATRIEFWAFDLLFLDGRS
MMAR_4573|M.marinum_M               DLADHHVVLDGELVALDSSGVPSFNEMQNRVRATRIEFWAFDLLFLDGRS
Mb0963|M.bovis_AF2122/97            DLADHHVVLDGEAVVLDSSGVPSFSQMQNRGRDTRVEFWAFDLLYLDGRA
Rv0938|M.tuberculosis_H37Rv         DLADHHVVLDGEAVVLDSSGVPSFSQMQNRGRDTRVEFWAFDLLYLDGRA
MAV_1056|M.avium_104                ALEEHHAVLDGEAVVLDKRGVPNFHEMQNRGKSARVEFWAFDLLYLDGRS
MAB_1033|M.abscessus_ATCC_1997      ELSDHRVVLDGEVVVPDRKGLPSFALLQNRTPGADIRFWAFDLLYLDGKS
                                     * :*:.:**** *. *  *:*.*  :***   : :.*****:*:***: 

Mflv_1828|M.gilvum_PYR-GCK          LTKATYTDRRKLLEALAEG-GGLIVPPALEGD-GPEALEYARSQRWEGVI
Mvan_4915|M.vanbaalenii_PYR-1       LLRAKYTDRRRVLEALADG-GGLIVPPLIGADTGAEALETARKRGWEGVV
MSMEG_5570|M.smegmatis_MC2_155      LLRAKYSDRRKILEALADG-GGLIVPDQLPGD-GPEAMEHVRKKRFEGVV
TH_3391|M.thermoresistible__bu      LLRAKHSDRRRVLLALAEK-DGLIVPDLLPGDTGAEALEYARERGFEGVV
MUL_4434|M.ulcerans_Agy99           LLRARYRDRRKLLETLGSA-GNLIVPELLPGD-GAEALAYSHKRGWEGVI
MMAR_4573|M.marinum_M               LLRARYRDRRKLLETLGSA-GNLIVPELLPGD-GAEALAYSHKRGWEGVI
Mb0963|M.bovis_AF2122/97            LLGTRYQDRRKLLETLANA-TSLTVPELLPGD-GAQAFACSRKHGWEGVI
Rv0938|M.tuberculosis_H37Rv         LLGTRYQDRRKLLETLANA-TSLTVPELLPGD-GAQAFACSRKHGWEGVI
MAV_1056|M.avium_104                LLRARYRDRRKLLEMLASG-GDLTVPELLPGD-GDQALRQSAERGWEGVI
MAB_1033|M.abscessus_ATCC_1997      LLRTKYRDRRRLLEVLVTGTESMTVPQQLSGD-GAAALAYSQDQGWEGVV
                                    *  : : ***::*  *     .: **  : .* *  *:    .: :***:

Mflv_1828|M.gilvum_PYR-GCK          AKKRDSTYQPGRRSSAWIKDKIWNTQEVVIGGWRQGEGGRTSGIGALVLG
Mvan_4915|M.vanbaalenii_PYR-1       AKKRDSTYQPGRRSSSWIKDKLWNTQEVVIGGWRQGEGGRTSGIGALMLG
MSMEG_5570|M.smegmatis_MC2_155      AKKWDSTYQPGRRSSSWIKDKIWNTQEVVIGGWRQGEGGRSSGIGALVLG
TH_3391|M.thermoresistible__bu      AKRHDSIYQPGRRSKAWIKDKIWNMQEVVIGGWRKGEGGRSSGIGALVLG
MUL_4434|M.ulcerans_Agy99           AKRRDSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGSLLMG
MMAR_4573|M.marinum_M               AKRRDSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGSLLMG
Mb0963|M.bovis_AF2122/97            AKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGSLLMG
Rv0938|M.tuberculosis_H37Rv         AKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGSLLMG
MAV_1056|M.avium_104                AKRRDSTYQPGRRSSSWIKDKHWNTQEVVIGGWKAGEGGRSSGIGSLLMG
MAB_1033|M.abscessus_ATCC_1997      AKRLDSTYVPG-RTQSWIKAKNWSSQEVVIGGWRKGQGGRSSGIGSLLMG
                                    **: ** * ** *  :*:* * *. ********: *:***:**:*:*::*

Mflv_1828|M.gilvum_PYR-GCK          VPDD---DGLHFVGRVGTGFTDKQLASLKKTLEPLRTDESPFAAELPKQD
Mvan_4915|M.vanbaalenii_PYR-1       IPAGGVAGGLQFVGRVGTGFTEKELASLKETLAPLHTDESPFATELPKQD
MSMEG_5570|M.smegmatis_MC2_155      IPGP---EGLQFVGRVGTGFTEKELSKLKDMLKPLHTDESPFNAPLPKVD
TH_3391|M.thermoresistible__bu      IPTE---GGLQFVGRVGTGFTDKQLAELKQLLAPLETDESPFVDPLPRPD
MUL_4434|M.ulcerans_Agy99           IPGP---SGLHFAGRVGTGFTERDLANLKKTLAPLHTDESPFDAALPARE
MMAR_4573|M.marinum_M               IPGP---SGLHFAGRVGTGFTERDLANLKKTLAPLHTDESPFDAALPARE
Mb0963|M.bovis_AF2122/97            IPGP---GGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPLPARD
Rv0938|M.tuberculosis_H37Rv         IPGP---GGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPLPARD
MAV_1056|M.avium_104                IPGP---GGLHFAGRVGTGFTERDLANLKKTLAPLRTDQSPFDAPLPRSE
MAB_1033|M.abscessus_ATCC_1997      IPVE---GGLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPLSTVE
                                    :*      **::.******:::::*:.**. * **.  :***   *.  :

Mflv_1828|M.gilvum_PYR-GCK          AKGVTFVRPELVGEVRYSERTSDGRLRQASWRGLRDDKVPEDVRWEG-
Mvan_4915|M.vanbaalenii_PYR-1       AKGVTFVRPELVGEVRYSERTSDNRLRQPSWRGLRTDKTPDEVVWE--
MSMEG_5570|M.smegmatis_MC2_155      ARGVTFVRPELVGEVRYSERTSDGRLRQPSWRGLRPDKTPDEVVWE--
TH_3391|M.thermoresistible__bu      AKGVTYVRPELVGEVRYSERTADNRLRQPSWRGLRPDKSPDEVRWE--
MUL_4434|M.ulcerans_Agy99           AKGVTFVVPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE--
MMAR_4573|M.marinum_M               AKGVTFVAPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE--
Mb0963|M.bovis_AF2122/97            AKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE--
Rv0938|M.tuberculosis_H37Rv         AKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE--
MAV_1056|M.avium_104                AKGVTFVEPVLVGEVRYSEWTPDDRLRQSSWRGLRPDKEASEVVRE--
MAB_1033|M.abscessus_ATCC_1997      AKDVQFVEPVLVAEVRYGDRTPGGILKHSSWRGLRTDKSVRDVELDLG
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