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MGSASEQRVTLTNADKVLYPATGTTKSDIFDYYAGVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLAL SAPPWLSRATVAHRSGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPGSGELNPGPATRLVFDLDP GEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHLYTPLDEPVSSRGATVLAKRVAQRLEQAMPAL VTSTMTKSLRAGKVFVDWSQNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIARD GDLLERLDADAPVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTFVIQEHHARRPHYDFRLECDGVLVS WAVPKNLPDNTSVNHLAIHTEDHPLEYATFEGAIPSGEYGAGKVIIWDSGTYDTEKFHDDPHTGEVIVNL HGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTVAGLKASQWAFEGKWDGYRLLVE ADHGAVRLRSRSGRDVTAEYPQLRALAEDLADHHVVLDGEAVVLDSSGVPSFSQMQNRGRDTRVEFWAFD LLYLDGRALLGTRYQDRRKLLETLANATSLTVPELLPGDGAQAFACSRKHGWEGVIAKRRDSRYQPGRRC ASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGSLLMGIPGPGGLQFAGRVGTGLSERELANLKEMLAPLHT DESPFDVPLPARDAKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0938 | - | - | 100% (759) | ATP-dependent DNA ligase |
M. tuberculosis H37Rv | Rv0269c | - | 2e-35 | 32.01% (328) | hypothetical protein Rv0269c |
M. tuberculosis H37Rv | Rv3730c | - | 3e-26 | 31.15% (260) | hypothetical protein Rv3730c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0963 | - | 0.0 | 99.87% (759) | ATP-dependent DNA ligase |
M. gilvum PYR-GCK | Mflv_1828 | - | 0.0 | 68.38% (759) | ATP-dependent DNA ligase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1033 | - | 0.0 | 67.20% (753) | ATP-dependent DNA ligase |
M. marinum M | MMAR_4573 | - | 0.0 | 81.54% (764) | ATP dependent DNA ligase |
M. avium 104 | MAV_1056 | - | 0.0 | 79.16% (758) | ATP-dependent DNA ligase |
M. smegmatis MC2 155 | MSMEG_5570 | - | 0.0 | 68.99% (761) | ATP-dependent DNA ligase |
M. thermoresistible (build 8) | TH_3391 | - | 0.0 | 68.64% (759) | PUTATIVE ATP dependent DNA ligase |
M. ulcerans Agy99 | MUL_4434 | - | 0.0 | 81.15% (764) | ATP-dependent DNA ligase |
M. vanbaalenii PYR-1 | Mvan_4915 | - | 0.0 | 70.80% (767) | ATP-dependent DNA ligase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1828|M.gilvum_PYR-GCK MVDRYDR------------VKLTNPDKVLYPASG-----TTKAQVFEYYV Mvan_4915|M.vanbaalenii_PYR-1 MVDRYER------------VKLTNPDKVLYPATGDRRRAVTKAEVFDYYV MSMEG_5570|M.smegmatis_MC2_155 -MERYER------------VRLTNPDKVLYPATG-----TTKAEVFDYYL TH_3391|M.thermoresistible__bu -MERYER------------VKLTNPDKVLYPASG-----TTKAEVFEYYI Rv0938|M.tuberculosis_H37Rv ---MGSASEQ--------RVTLTNADKVLYPATG-----TTKSDIFDYYA Mb0963|M.bovis_AF2122/97 ---MGSASEQ--------RVTLTNADKVLYPATG-----TTKSDIFDYYA MMAR_4573|M.marinum_M ---MGSAQAWPPGQANGPQVTLTNADKVLYPATG-----TTKSDVFGYYT MUL_4434|M.ulcerans_Agy99 ---MGSAQAWPPGQANGPQVTLTNADKVLYPATG-----TTKSDVFGYYT MAV_1056|M.avium_104 ---MNAPRAWPAEPTATPRVKLTNADKVLYPATG-----TTKADVFDYYT MAB_1033|M.abscessus_ATCC_1997 ---------------------------MLYPATDTSP-ATTKADVFGYYT :****:. .**:::* ** Mflv_1828|M.gilvum_PYR-GCK NVAEGMLPHIAGRAVTRKRWPNGVEESSFFEKQLASSAPDWLDRGTIAHK Mvan_4915|M.vanbaalenii_PYR-1 NVAAAMLPHIAGRAVTRKRWPNGVTEESFFEKQLASSAPDWLGRGTIVHK MSMEG_5570|M.smegmatis_MC2_155 SIAQVMVPHIAGRPVTRKRWPNGVAEEAFFEKQLASSAPSWLERGSITHK TH_3391|M.thermoresistible__bu EIADAMLPHIAGRPVTRKRWPNGVHEASFFEKQLASSAPDWLARGTITHK Rv0938|M.tuberculosis_H37Rv GVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHR Mb0963|M.bovis_AF2122/97 GVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHR MMAR_4573|M.marinum_M GIAEVMIPHIAGRPATRKRWPNGVDQASFFEKQLASSAPDWLPRASVVHR MUL_4434|M.ulcerans_Agy99 GIAEVMIPHIAGRPATRKRWPNGVDQASFFEKQLASSAPDWLPRASVVHR MAV_1056|M.avium_104 RIADVMIPHIAGRPVTRKRWPNGVDQESFFEKQLASSAPDWLPRASVTHR MAB_1033|M.abscessus_ATCC_1997 AIAPFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSAPDWLPRRRIEHK :* *: *****..********: : :****:** *** ** * : *: Mflv_1828|M.gilvum_PYR-GCK SGTTTYPVIDTVEGLAWIAQQAALEVHVPQWRFTRGGQSGAADGGDGKPG Mvan_4915|M.vanbaalenii_PYR-1 SGTTTYPVIDTVEGLAWIAQQAALEVHVPQWRFV-----------DGSVG MSMEG_5570|M.smegmatis_MC2_155 SGTTTYPIINTREGLAWVAQQASLEVHVPQWRFEDGDQ-----------G TH_3391|M.thermoresistible__bu SRTTTYPIIDTREGLAWIAQQAALEVHVPQWRFVAGGRSGR--DGKLTMG Rv0938|M.tuberculosis_H37Rv SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPG---SGE--LNPG Mb0963|M.bovis_AF2122/97 SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPG---SGE--LNPG MMAR_4573|M.marinum_M SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWT---SKGEILTPG MUL_4434|M.ulcerans_Agy99 SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWT---SKGEILTPG MAV_1056|M.avium_104 SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTR--SRAEELKPG MAB_1033|M.abscessus_ATCC_1997 SRYVSYPLIDTSVALAWIAQQAALEVHVPQWRFAGENP-----------G * .:**:*:: .***:****:********** * Mflv_1828|M.gilvum_PYR-GCK PATRIVFDLDPGEGVTFRQLCEVAHEVRELITDIGLTTFPLTSGSKGLHL Mvan_4915|M.vanbaalenii_PYR-1 PATRIVFDLDPGEGVTFRQLCEVANEVRDLLADIGLRTFPLTSGSKGLHL MSMEG_5570|M.smegmatis_MC2_155 PATRIVFDLDPGEGVTMTQLCEIAHEVRALMTDLDLETYPLTSGSKGLHL TH_3391|M.thermoresistible__bu PATRIVFDLDPGEGVTMRELCRVAHEVRDLITDIGLDTFPLTSGSKGLHL Rv0938|M.tuberculosis_H37Rv PATRLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHL Mb0963|M.bovis_AF2122/97 PATRLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHL MMAR_4573|M.marinum_M PATRLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHL MUL_4434|M.ulcerans_Agy99 PATRLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHF MAV_1056|M.avium_104 PATRLVFDLDPGEGVTMAQLAEVARAVRDLIDGIGLQTFPLTSGSKGLHL MAB_1033|M.abscessus_ATCC_1997 PATRLVFDLDPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLHL ****:********** : :*..:*. :* :: .:.* * *:********: Mflv_1828|M.gilvum_PYR-GCK YVPLEDPISSRGASVLAKRVAQQLEQSMPKRVTATMTKSLRDGKVFLDWS Mvan_4915|M.vanbaalenii_PYR-1 YVPLDEPISSRGASVLAKRVAQQLEQAMPMQVTATMTKSLRTGKVFVDWS MSMEG_5570|M.smegmatis_MC2_155 YVPLAEPISSRGASVLARRVAQQLEQAMPKLVTATMTKSLRAGKVFLDWS TH_3391|M.thermoresistible__bu YVPLDEPISSQGASVLAKRVALQLEKAMPTLVTATMTKSVRTGKVFLDWS Rv0938|M.tuberculosis_H37Rv YTPLDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWS Mb0963|M.bovis_AF2122/97 YTPLDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWS MMAR_4573|M.marinum_M YTPLDEPVSSKGATVLAKRVAQQLETVMPALVTATMTKSLRAGKVFLDWS MUL_4434|M.ulcerans_Agy99 YTPLDEPVSSKGATVLAKRVAQQLETVMPALVTATMTKSLRAGKVFLDWS MAV_1056|M.avium_104 YTPLTEPVSSKGATVLAKRVAQQLEKTMPKLVTSTMTKSLRAGKIFVDWS MAB_1033|M.abscessus_ATCC_1997 YVPLAQPASSSGAVAVAKKVAVQLEQVMPDLVTATMTRQLRAGKVFVDWS *.** :* ** ** .:*::** :** ** **:***:.:* **:*:*** Mflv_1828|M.gilvum_PYR-GCK QNNGNKTTIAPYSLRGRERPTVAAPRTWDEIEDPDLRHLTFDEVLDRLER Mvan_4915|M.vanbaalenii_PYR-1 QNNANKTTIAPYSLRGREHPTVAAPRTWEEISDPDLRQLTFDEVLDRLDR MSMEG_5570|M.smegmatis_MC2_155 QNNAAKTTIAPYSLRGRDHPTVAAPRTWDEIADPELRHLRFDEVLDRLDE TH_3391|M.thermoresistible__bu QNNAAKTTIAPYSLRGREHPTVAAPRTWDEIDDPDLRHLTFTEVLDRVDR Rv0938|M.tuberculosis_H37Rv QNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIAR Mb0963|M.bovis_AF2122/97 QNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIAR MMAR_4573|M.marinum_M QNSGSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYDEVLARLTR MUL_4434|M.ulcerans_Agy99 QNSGSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYDEVLARLTR MAV_1056|M.avium_104 QNNGSKTTIAPYSLRGRDHPTVAAPRTWDELDDPALRHLRYDEVLTRVAR MAB_1033|M.abscessus_ATCC_1997 QNSGSKTTVAPYSLRGRAVPTVAAPRTWEELDDPGLRQLRYDEVLTRAQR **.. ***:******** *******:* *: ** **:* : *** * . Mflv_1828|M.gilvum_PYR-GCK DGDLLADLDPP---LPATDKLTRYRSMRDRTKTPEPVPAEPPETGANDKF Mvan_4915|M.vanbaalenii_PYR-1 DGDLLAGLDPP---VPVPDRLTRYRSMRDTAKTPEPIPGDAPTTGNNDKF MSMEG_5570|M.smegmatis_MC2_155 YGDLLAPLDAD---APIADKLTTYRSMRDASKTPEPVPKEIPKTGNNDKF TH_3391|M.thermoresistible__bu LGDLLAPMDAD---APVADRLSSYRSMRDPARTPEPVPKTVAATGDDNRF Rv0938|M.tuberculosis_H37Rv DGDLLERLDAD---APVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTF Mb0963|M.bovis_AF2122/97 DGDLLERLDAD---APVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTF MMAR_4573|M.marinum_M DGDLIAALDAD---LPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTF MUL_4434|M.ulcerans_Agy99 DGDLIAALDAD---LPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTF MAV_1056|M.avium_104 DGDLLAELDASDNQTPVPDRLTKYRSMRDASKTPEPVPAAKPAAGRGNTF MAB_1033|M.abscessus_ATCC_1997 DGDLLAGLDDV---EIAEDRLSTYRSMRDPTRTPEPVPAVKPEAGQDNSF ***: :* *:* ** **: ::****:* . .* .: * Mflv_1828|M.gilvum_PYR-GCK VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPSVNHLAVHTEDHPMD Mvan_4915|M.vanbaalenii_PYR-1 VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPSVNHLAVHTEDHPME MSMEG_5570|M.smegmatis_MC2_155 VIQEHHARRLHYDLRLERDGVLVSFAVPKNLPETTAENRLAVHTEDHPIE TH_3391|M.thermoresistible__bu VIQEHHARRLHYDLRLERDGVLVSWAIPKNLPDDPSVNHLAVHTEDHPLE Rv0938|M.tuberculosis_H37Rv VIQEHHARRPHYDFRLECDGVLVSWAVPKNLPDNTSVNHLAIHTEDHPLE Mb0963|M.bovis_AF2122/97 VIQEHHARRPHYDFRLERDGVLVSWAVPKNLPDNTSVNHLAIHTEDHPLE MMAR_4573|M.marinum_M VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLE MUL_4434|M.ulcerans_Agy99 VIQEHHARRLHDDFRLERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLE MAV_1056|M.avium_104 VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPAVNHLAVHTEDHPLE MAB_1033|M.abscessus_ATCC_1997 VIQEHHATALHYDFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLE ******* * *:*** ******:*:***** .: *:**:******:: Mflv_1828|M.gilvum_PYR-GCK YIDFAGEIPKGEYGGGEVHIWDTGTYETEKFR---DNPPDGPAKGGEVIV Mvan_4915|M.vanbaalenii_PYR-1 YLTFAGEIPRGEYGGGEVYIWDTGTYETEKFR---DNPPDGPDRGGEVIV MSMEG_5570|M.smegmatis_MC2_155 YLAFHGSIPKGEYGAGDMVIWDSGSYETEKFRVP-EELDNPDDSHGEIIV TH_3391|M.thermoresistible__bu YLTFHGEIPEGEYGGGKMLIWDTGTYEAEKFN---DVGPDEDAEGGEVII Rv0938|M.tuberculosis_H37Rv YATFEGAIPSGEYGAGKVIIWDSGTYDTEKFH----DDPHTG----EVIV Mb0963|M.bovis_AF2122/97 YATFEGAIPSGEYGAGKVIIWDSGTYDTEKFH----DDPHTG----EVIV MMAR_4573|M.marinum_M YATFEGNIPKGEYGAGKVIIWDSGTYDTEKFR----DDSRNGSEKGEVIV MUL_4434|M.ulcerans_Agy99 YATFEGNIPKGEYGAGKVIIWDSGTYDTEKFR----DDSRNGAEKGEVIV MAV_1056|M.avium_104 YGGFEGVIPKGEYGAGRVVIWDSGTYDAEKFQ----DD--------EVIV MAB_1033|M.abscessus_ATCC_1997 YGSFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADGGQKGEVIV * * * ** ****.* : ***:*:*::*** *:*: Mflv_1828|M.gilvum_PYR-GCK TLHGQKIEGRYALIQTDGKNWLAHRMKDQQ---KPTAADLAPMLTTEGSV Mvan_4915|M.vanbaalenii_PYR-1 TLHGEKIDGRYALIQTDGKNWLAHRMKDQQ---RPTAADLAPMLTTHGSV MSMEG_5570|M.smegmatis_MC2_155 TLHGEKVDGRYALIQTKGKNWLAHRMKDQK---NARPEDFAPMLATEGSV TH_3391|M.thermoresistible__bu TLHGEKISGRYALIQTDGKNWLAHKMKDQKPRTEIRPEDFTPMLATHGSV Rv0938|M.tuberculosis_H37Rv NLHGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTV Mb0963|M.bovis_AF2122/97 NLHGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTV MMAR_4573|M.marinum_M NLHGSRISGRYALIQTNGDQWLAHRMK---DQTAFDFDTLAPMLTSHGSV MUL_4434|M.ulcerans_Agy99 NLHGSRISGRYALIQTNGDQWLAHRMK---DQTAFDFDTLAPMLTSHGSV MAV_1056|M.avium_104 NLHGRKISGRYALIQTEGDQWLAHRMK---DQNVFDFDTIAPMLATHGSV MAB_1033|M.abscessus_ATCC_1997 TLHGKRITGRYALIRTNGKQWLVHRMKDQRPAGSMPVG-LAPMLPTTGSV .*** :: ******:*.*..**.*::* ::***.: *:* Mflv_1828|M.gilvum_PYR-GCK ERLTRGQWAFEGKWDGYRLLVDADHGKLTLRSRRGRDVTAEYPQLKALAA Mvan_4915|M.vanbaalenii_PYR-1 QRLTKGQWAFEGKWDGYRLLVEADHGRLALRSRNGRDVTAEYPQLQALAA MSMEG_5570|M.smegmatis_MC2_155 AKYKAKQWAFEGKWDGYRVIIDADHGQLQIRSRTGREVTGEYPQFKALAA TH_3391|M.thermoresistible__bu ARLSAETHAFEGKWDGYRLLVHIDHGKLCLRSRSGRDVTKEFPTLQAMAA Rv0938|M.tuberculosis_H37Rv AGLKASQWAFEGKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAE Mb0963|M.bovis_AF2122/97 AGLKASQWAFEGKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAE MMAR_4573|M.marinum_M AGLESGQWAFEGKWDGYRLLVEADHGALRLRSRSGRDVTAEYPQLRSLAA MUL_4434|M.ulcerans_Agy99 AGLESGQWAFEGKWDGYRLLVEADHGALRLRSRSGRDVTTEYPQLRSLAA MAV_1056|M.avium_104 SALKASQWAFEGKWDGYRLLVEADHGTLRVRSRRGREVTGEYRELRSLAK MAB_1033|M.abscessus_ATCC_1997 AGLTAEEWAFEGKWDGYRLILECDRGQLRALARSGRDVTAEFPALQRLAH **********:::. *:* : :* **:** *: :: :* Mflv_1828|M.gilvum_PYR-GCK DLADHHVILDGEAVALDEDGVPSFGEMQNRARSTRVEFWAFDILFLDGRL Mvan_4915|M.vanbaalenii_PYR-1 DLADHHVILDGEAVALDESGVPSFREMQNRARSTRVEFWAFDILFLDGRS MSMEG_5570|M.smegmatis_MC2_155 DLAEHHVVLDGEAVALDESGVPSFGQMQNRARSTRVEFWAFDILWLDGRS TH_3391|M.thermoresistible__bu DLADHQVVLDGEVVALDGSGVPSFGEMQNRARATHIEFWAFDILWLDGRS Rv0938|M.tuberculosis_H37Rv DLADHHVVLDGEAVVLDSSGVPSFSQMQNRGRDTRVEFWAFDLLYLDGRA Mb0963|M.bovis_AF2122/97 DLADHHVVLDGEAVVLDSSGVPSFSQMQNRGRDTRVEFWAFDLLYLDGRA MMAR_4573|M.marinum_M DLADHHVVLDGELVALDSSGVPSFNEMQNRVRATRIEFWAFDLLFLDGRS MUL_4434|M.ulcerans_Agy99 DLADHHVVLDGELVALDSSGVPSFNEMQNRVRATRIEFWAFDLLFLDGRS MAV_1056|M.avium_104 ALEEHHAVLDGEAVVLDKRGVPNFHEMQNRGKSARVEFWAFDLLYLDGRS MAB_1033|M.abscessus_ATCC_1997 ELSDHRVVLDGEVVVPDRKGLPSFALLQNRTPGADIRFWAFDLLYLDGKS * :*:.:**** *. * *:*.* :*** : :.*****:*:***: Mflv_1828|M.gilvum_PYR-GCK LTKATYTDRRKLLEALAEG-GGLIVPPALEGD-GPEALEYARSQRWEGVI Mvan_4915|M.vanbaalenii_PYR-1 LLRAKYTDRRRVLEALADG-GGLIVPPLIGADTGAEALETARKRGWEGVV MSMEG_5570|M.smegmatis_MC2_155 LLRAKYSDRRKILEALADG-GGLIVPDQLPGD-GPEAMEHVRKKRFEGVV TH_3391|M.thermoresistible__bu LLRAKHSDRRRVLLALAEK-DGLIVPDLLPGDTGAEALEYARERGFEGVV Rv0938|M.tuberculosis_H37Rv LLGTRYQDRRKLLETLANA-TSLTVPELLPGD-GAQAFACSRKHGWEGVI Mb0963|M.bovis_AF2122/97 LLGTRYQDRRKLLETLANA-TSLTVPELLPGD-GAQAFACSRKHGWEGVI MMAR_4573|M.marinum_M LLRARYRDRRKLLETLGSA-GNLIVPELLPGD-GAEALAYSHKRGWEGVI MUL_4434|M.ulcerans_Agy99 LLRARYRDRRKLLETLGSA-GNLIVPELLPGD-GAEALAYSHKRGWEGVI MAV_1056|M.avium_104 LLRARYRDRRKLLEMLASG-GDLTVPELLPGD-GDQALRQSAERGWEGVI MAB_1033|M.abscessus_ATCC_1997 LLRTKYRDRRRLLEVLVTGTESMTVPQQLSGD-GAAALAYSQDQGWEGVV * : : ***::* * .: ** : .* * *: .: :***: Mflv_1828|M.gilvum_PYR-GCK AKKRDSTYQPGRRSSAWIKDKIWNTQEVVIGGWRQGEGGRTSGIGALVLG Mvan_4915|M.vanbaalenii_PYR-1 AKKRDSTYQPGRRSSSWIKDKLWNTQEVVIGGWRQGEGGRTSGIGALMLG MSMEG_5570|M.smegmatis_MC2_155 AKKWDSTYQPGRRSSSWIKDKIWNTQEVVIGGWRQGEGGRSSGIGALVLG TH_3391|M.thermoresistible__bu AKRHDSIYQPGRRSKAWIKDKIWNMQEVVIGGWRKGEGGRSSGIGALVLG Rv0938|M.tuberculosis_H37Rv AKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGSLLMG Mb0963|M.bovis_AF2122/97 AKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGSLLMG MMAR_4573|M.marinum_M AKRRDSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGSLLMG MUL_4434|M.ulcerans_Agy99 AKRRDSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGSLLMG MAV_1056|M.avium_104 AKRRDSTYQPGRRSSSWIKDKHWNTQEVVIGGWKAGEGGRSSGIGSLLMG MAB_1033|M.abscessus_ATCC_1997 AKRLDSTYVPG-RTQSWIKAKNWSSQEVVIGGWRKGQGGRSSGIGSLLMG **: ** * ** * :*:* * *. ********: *:***:**:*:*::* Mflv_1828|M.gilvum_PYR-GCK VPDD---DGLHFVGRVGTGFTDKQLASLKKTLEPLRTDESPFAAELPKQD Mvan_4915|M.vanbaalenii_PYR-1 IPAGGVAGGLQFVGRVGTGFTEKELASLKETLAPLHTDESPFATELPKQD MSMEG_5570|M.smegmatis_MC2_155 IPGP---EGLQFVGRVGTGFTEKELSKLKDMLKPLHTDESPFNAPLPKVD TH_3391|M.thermoresistible__bu IPTE---GGLQFVGRVGTGFTDKQLAELKQLLAPLETDESPFVDPLPRPD Rv0938|M.tuberculosis_H37Rv IPGP---GGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPLPARD Mb0963|M.bovis_AF2122/97 IPGP---GGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPLPARD MMAR_4573|M.marinum_M IPGP---SGLHFAGRVGTGFTERDLANLKKTLAPLHTDESPFDAALPARE MUL_4434|M.ulcerans_Agy99 IPGP---SGLHFAGRVGTGFTERDLANLKKTLAPLHTDESPFDAALPARE MAV_1056|M.avium_104 IPGP---GGLHFAGRVGTGFTERDLANLKKTLAPLRTDQSPFDAPLPRSE MAB_1033|M.abscessus_ATCC_1997 IPVE---GGLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPLSTVE :* **::.******:::::*:.**. * **. :*** *. : Mflv_1828|M.gilvum_PYR-GCK AKGVTFVRPELVGEVRYSERTSDGRLRQASWRGLRDDKVPEDVRWEG- Mvan_4915|M.vanbaalenii_PYR-1 AKGVTFVRPELVGEVRYSERTSDNRLRQPSWRGLRTDKTPDEVVWE-- MSMEG_5570|M.smegmatis_MC2_155 ARGVTFVRPELVGEVRYSERTSDGRLRQPSWRGLRPDKTPDEVVWE-- TH_3391|M.thermoresistible__bu AKGVTYVRPELVGEVRYSERTADNRLRQPSWRGLRPDKSPDEVRWE-- Rv0938|M.tuberculosis_H37Rv AKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE-- Mb0963|M.bovis_AF2122/97 AKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE-- MMAR_4573|M.marinum_M AKGVTFVAPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE-- MUL_4434|M.ulcerans_Agy99 AKGVTFVVPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE-- MAV_1056|M.avium_104 AKGVTFVEPVLVGEVRYSEWTPDDRLRQSSWRGLRPDKEASEVVRE-- MAB_1033|M.abscessus_ATCC_1997 AKDVQFVEPVLVAEVRYGDRTPGGILKHSSWRGLRTDKSVRDVELDLG *:.: :* * **.****.: *. . *::.****** ** :* :