For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv0938 (-)

annotation: ATP-dependent DNA ligase
coordinates: 1046136 - 1048415
length: 759

MGSASEQRVTLTNADKVLYPATGTTKSDIFDYYAGVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLAL
SAPPWLSRATVAHRSGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPGSGELNPGPATRLVFDLDP
GEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHLYTPLDEPVSSRGATVLAKRVAQRLEQAMPAL
VTSTMTKSLRAGKVFVDWSQNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIARD
GDLLERLDADAPVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTFVIQEHHARRPHYDFRLECDGVLVS
WAVPKNLPDNTSVNHLAIHTEDHPLEYATFEGAIPSGEYGAGKVIIWDSGTYDTEKFHDDPHTGEVIVNL
HGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTVAGLKASQWAFEGKWDGYRLLVE
ADHGAVRLRSRSGRDVTAEYPQLRALAEDLADHHVVLDGEAVVLDSSGVPSFSQMQNRGRDTRVEFWAFD
LLYLDGRALLGTRYQDRRKLLETLANATSLTVPELLPGDGAQAFACSRKHGWEGVIAKRRDSRYQPGRRC
ASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGSLLMGIPGPGGLQFAGRVGTGLSERELANLKEMLAPLHT
DESPFDVPLPARDAKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0938--100% (759)ATP-dependent DNA ligase
M. tuberculosis H37RvRv0269c-2e-3532.01% (328) hypothetical protein Rv0269c
M. tuberculosis H37RvRv3730c-3e-2631.15% (260) hypothetical protein Rv3730c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0963-0.099.87% (759) ATP-dependent DNA ligase
M. gilvum PYR-GCKMflv_1828-0.068.38% (759) ATP-dependent DNA ligase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1033-0.067.20% (753) ATP-dependent DNA ligase
M. marinum MMMAR_4573-0.081.54% (764) ATP dependent DNA ligase
M. avium 104MAV_1056-0.079.16% (758) ATP-dependent DNA ligase
M. smegmatis MC2 155MSMEG_5570-0.068.99% (761) ATP-dependent DNA ligase
M. thermoresistible (build 8)TH_3391-0.068.64% (759) PUTATIVE ATP dependent DNA ligase
M. ulcerans Agy99MUL_4434-0.081.15% (764) ATP-dependent DNA ligase
M. vanbaalenii PYR-1Mvan_4915-0.070.80% (767) ATP-dependent DNA ligase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1828|M.gilvum_PYR-GCK          MVDRYDR------------VKLTNPDKVLYPASG-----TTKAQVFEYYV
Mvan_4915|M.vanbaalenii_PYR-1       MVDRYER------------VKLTNPDKVLYPATGDRRRAVTKAEVFDYYV
MSMEG_5570|M.smegmatis_MC2_155      -MERYER------------VRLTNPDKVLYPATG-----TTKAEVFDYYL
TH_3391|M.thermoresistible__bu      -MERYER------------VKLTNPDKVLYPASG-----TTKAEVFEYYI
Rv0938|M.tuberculosis_H37Rv         ---MGSASEQ--------RVTLTNADKVLYPATG-----TTKSDIFDYYA
Mb0963|M.bovis_AF2122/97            ---MGSASEQ--------RVTLTNADKVLYPATG-----TTKSDIFDYYA
MMAR_4573|M.marinum_M               ---MGSAQAWPPGQANGPQVTLTNADKVLYPATG-----TTKSDVFGYYT
MUL_4434|M.ulcerans_Agy99           ---MGSAQAWPPGQANGPQVTLTNADKVLYPATG-----TTKSDVFGYYT
MAV_1056|M.avium_104                ---MNAPRAWPAEPTATPRVKLTNADKVLYPATG-----TTKADVFDYYT
MAB_1033|M.abscessus_ATCC_1997      ---------------------------MLYPATDTSP-ATTKADVFGYYT
                                                               :****:.     .**:::* ** 

Mflv_1828|M.gilvum_PYR-GCK          NVAEGMLPHIAGRAVTRKRWPNGVEESSFFEKQLASSAPDWLDRGTIAHK
Mvan_4915|M.vanbaalenii_PYR-1       NVAAAMLPHIAGRAVTRKRWPNGVTEESFFEKQLASSAPDWLGRGTIVHK
MSMEG_5570|M.smegmatis_MC2_155      SIAQVMVPHIAGRPVTRKRWPNGVAEEAFFEKQLASSAPSWLERGSITHK
TH_3391|M.thermoresistible__bu      EIADAMLPHIAGRPVTRKRWPNGVHEASFFEKQLASSAPDWLARGTITHK
Rv0938|M.tuberculosis_H37Rv         GVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHR
Mb0963|M.bovis_AF2122/97            GVAEVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHR
MMAR_4573|M.marinum_M               GIAEVMIPHIAGRPATRKRWPNGVDQASFFEKQLASSAPDWLPRASVVHR
MUL_4434|M.ulcerans_Agy99           GIAEVMIPHIAGRPATRKRWPNGVDQASFFEKQLASSAPDWLPRASVVHR
MAV_1056|M.avium_104                RIADVMIPHIAGRPVTRKRWPNGVDQESFFEKQLASSAPDWLPRASVTHR
MAB_1033|M.abscessus_ATCC_1997      AIAPFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSAPDWLPRRRIEHK
                                     :*  *: *****..********: : :****:** *** ** *  : *:

Mflv_1828|M.gilvum_PYR-GCK          SGTTTYPVIDTVEGLAWIAQQAALEVHVPQWRFTRGGQSGAADGGDGKPG
Mvan_4915|M.vanbaalenii_PYR-1       SGTTTYPVIDTVEGLAWIAQQAALEVHVPQWRFV-----------DGSVG
MSMEG_5570|M.smegmatis_MC2_155      SGTTTYPIINTREGLAWVAQQASLEVHVPQWRFEDGDQ-----------G
TH_3391|M.thermoresistible__bu      SRTTTYPIIDTREGLAWIAQQAALEVHVPQWRFVAGGRSGR--DGKLTMG
Rv0938|M.tuberculosis_H37Rv         SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPG---SGE--LNPG
Mb0963|M.bovis_AF2122/97            SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPG---SGE--LNPG
MMAR_4573|M.marinum_M               SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWT---SKGEILTPG
MUL_4434|M.ulcerans_Agy99           SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWT---SKGEILTPG
MAV_1056|M.avium_104                SGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTR--SRAEELKPG
MAB_1033|M.abscessus_ATCC_1997      SRYVSYPLIDTSVALAWIAQQAALEVHVPQWRFAGENP-----------G
                                    *  .:**:*::  .***:****:**********                *

Mflv_1828|M.gilvum_PYR-GCK          PATRIVFDLDPGEGVTFRQLCEVAHEVRELITDIGLTTFPLTSGSKGLHL
Mvan_4915|M.vanbaalenii_PYR-1       PATRIVFDLDPGEGVTFRQLCEVANEVRDLLADIGLRTFPLTSGSKGLHL
MSMEG_5570|M.smegmatis_MC2_155      PATRIVFDLDPGEGVTMTQLCEIAHEVRALMTDLDLETYPLTSGSKGLHL
TH_3391|M.thermoresistible__bu      PATRIVFDLDPGEGVTMRELCRVAHEVRDLITDIGLDTFPLTSGSKGLHL
Rv0938|M.tuberculosis_H37Rv         PATRLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHL
Mb0963|M.bovis_AF2122/97            PATRLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHL
MMAR_4573|M.marinum_M               PATRLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHL
MUL_4434|M.ulcerans_Agy99           PATRLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHF
MAV_1056|M.avium_104                PATRLVFDLDPGEGVTMAQLAEVARAVRDLIDGIGLQTFPLTSGSKGLHL
MAB_1033|M.abscessus_ATCC_1997      PATRLVFDLDPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLHL
                                    ****:********** : :*..:*. :* :: .:.* * *:********:

Mflv_1828|M.gilvum_PYR-GCK          YVPLEDPISSRGASVLAKRVAQQLEQSMPKRVTATMTKSLRDGKVFLDWS
Mvan_4915|M.vanbaalenii_PYR-1       YVPLDEPISSRGASVLAKRVAQQLEQAMPMQVTATMTKSLRTGKVFVDWS
MSMEG_5570|M.smegmatis_MC2_155      YVPLAEPISSRGASVLARRVAQQLEQAMPKLVTATMTKSLRAGKVFLDWS
TH_3391|M.thermoresistible__bu      YVPLDEPISSQGASVLAKRVALQLEKAMPTLVTATMTKSVRTGKVFLDWS
Rv0938|M.tuberculosis_H37Rv         YTPLDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWS
Mb0963|M.bovis_AF2122/97            YTPLDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWS
MMAR_4573|M.marinum_M               YTPLDEPVSSKGATVLAKRVAQQLETVMPALVTATMTKSLRAGKVFLDWS
MUL_4434|M.ulcerans_Agy99           YTPLDEPVSSKGATVLAKRVAQQLETVMPALVTATMTKSLRAGKVFLDWS
MAV_1056|M.avium_104                YTPLTEPVSSKGATVLAKRVAQQLEKTMPKLVTSTMTKSLRAGKIFVDWS
MAB_1033|M.abscessus_ATCC_1997      YVPLAQPASSSGAVAVAKKVAVQLEQVMPDLVTATMTRQLRAGKVFVDWS
                                    *.** :* ** ** .:*::** :**  **  **:***:.:* **:*:***

Mflv_1828|M.gilvum_PYR-GCK          QNNGNKTTIAPYSLRGRERPTVAAPRTWDEIEDPDLRHLTFDEVLDRLER
Mvan_4915|M.vanbaalenii_PYR-1       QNNANKTTIAPYSLRGREHPTVAAPRTWEEISDPDLRQLTFDEVLDRLDR
MSMEG_5570|M.smegmatis_MC2_155      QNNAAKTTIAPYSLRGRDHPTVAAPRTWDEIADPELRHLRFDEVLDRLDE
TH_3391|M.thermoresistible__bu      QNNAAKTTIAPYSLRGREHPTVAAPRTWDEIDDPDLRHLTFTEVLDRVDR
Rv0938|M.tuberculosis_H37Rv         QNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIAR
Mb0963|M.bovis_AF2122/97            QNSGSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIAR
MMAR_4573|M.marinum_M               QNSGSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYDEVLARLTR
MUL_4434|M.ulcerans_Agy99           QNSGSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYDEVLARLTR
MAV_1056|M.avium_104                QNNGSKTTIAPYSLRGRDHPTVAAPRTWDELDDPALRHLRYDEVLTRVAR
MAB_1033|M.abscessus_ATCC_1997      QNSGSKTTVAPYSLRGRAVPTVAAPRTWEELDDPGLRQLRYDEVLTRAQR
                                    **.. ***:********  *******:* *: ** **:* : *** *  .

Mflv_1828|M.gilvum_PYR-GCK          DGDLLADLDPP---LPATDKLTRYRSMRDRTKTPEPVPAEPPETGANDKF
Mvan_4915|M.vanbaalenii_PYR-1       DGDLLAGLDPP---VPVPDRLTRYRSMRDTAKTPEPIPGDAPTTGNNDKF
MSMEG_5570|M.smegmatis_MC2_155      YGDLLAPLDAD---APIADKLTTYRSMRDASKTPEPVPKEIPKTGNNDKF
TH_3391|M.thermoresistible__bu      LGDLLAPMDAD---APVADRLSSYRSMRDPARTPEPVPKTVAATGDDNRF
Rv0938|M.tuberculosis_H37Rv         DGDLLERLDAD---APVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTF
Mb0963|M.bovis_AF2122/97            DGDLLERLDAD---APVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTF
MMAR_4573|M.marinum_M               DGDLIAALDAD---LPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTF
MUL_4434|M.ulcerans_Agy99           DGDLIAALDAD---LPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTF
MAV_1056|M.avium_104                DGDLLAELDASDNQTPVPDRLTKYRSMRDASKTPEPVPAAKPAAGRGNTF
MAB_1033|M.abscessus_ATCC_1997      DGDLLAGLDDV---EIAEDRLSTYRSMRDPTRTPEPVPAVKPEAGQDNSF
                                     ***:  :*         *:*  ** **: ::****:*   . .* .: *

Mflv_1828|M.gilvum_PYR-GCK          VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPSVNHLAVHTEDHPMD
Mvan_4915|M.vanbaalenii_PYR-1       VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPSVNHLAVHTEDHPME
MSMEG_5570|M.smegmatis_MC2_155      VIQEHHARRLHYDLRLERDGVLVSFAVPKNLPETTAENRLAVHTEDHPIE
TH_3391|M.thermoresistible__bu      VIQEHHARRLHYDLRLERDGVLVSWAIPKNLPDDPSVNHLAVHTEDHPLE
Rv0938|M.tuberculosis_H37Rv         VIQEHHARRPHYDFRLECDGVLVSWAVPKNLPDNTSVNHLAIHTEDHPLE
Mb0963|M.bovis_AF2122/97            VIQEHHARRPHYDFRLERDGVLVSWAVPKNLPDNTSVNHLAIHTEDHPLE
MMAR_4573|M.marinum_M               VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLE
MUL_4434|M.ulcerans_Agy99           VIQEHHARRLHDDFRLERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLE
MAV_1056|M.avium_104                VIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPAVNHLAVHTEDHPLE
MAB_1033|M.abscessus_ATCC_1997      VIQEHHATALHYDFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLE
                                    *******   * *:*** ******:*:*****  .: *:**:******::

Mflv_1828|M.gilvum_PYR-GCK          YIDFAGEIPKGEYGGGEVHIWDTGTYETEKFR---DNPPDGPAKGGEVIV
Mvan_4915|M.vanbaalenii_PYR-1       YLTFAGEIPRGEYGGGEVYIWDTGTYETEKFR---DNPPDGPDRGGEVIV
MSMEG_5570|M.smegmatis_MC2_155      YLAFHGSIPKGEYGAGDMVIWDSGSYETEKFRVP-EELDNPDDSHGEIIV
TH_3391|M.thermoresistible__bu      YLTFHGEIPEGEYGGGKMLIWDTGTYEAEKFN---DVGPDEDAEGGEVII
Rv0938|M.tuberculosis_H37Rv         YATFEGAIPSGEYGAGKVIIWDSGTYDTEKFH----DDPHTG----EVIV
Mb0963|M.bovis_AF2122/97            YATFEGAIPSGEYGAGKVIIWDSGTYDTEKFH----DDPHTG----EVIV
MMAR_4573|M.marinum_M               YATFEGNIPKGEYGAGKVIIWDSGTYDTEKFR----DDSRNGSEKGEVIV
MUL_4434|M.ulcerans_Agy99           YATFEGNIPKGEYGAGKVIIWDSGTYDTEKFR----DDSRNGAEKGEVIV
MAV_1056|M.avium_104                YGGFEGVIPKGEYGAGRVVIWDSGTYDAEKFQ----DD--------EVIV
MAB_1033|M.abscessus_ATCC_1997      YGSFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADGGQKGEVIV
                                    *  * * ** ****.* : ***:*:*::***               *:*:

Mflv_1828|M.gilvum_PYR-GCK          TLHGQKIEGRYALIQTDGKNWLAHRMKDQQ---KPTAADLAPMLTTEGSV
Mvan_4915|M.vanbaalenii_PYR-1       TLHGEKIDGRYALIQTDGKNWLAHRMKDQQ---RPTAADLAPMLTTHGSV
MSMEG_5570|M.smegmatis_MC2_155      TLHGEKVDGRYALIQTKGKNWLAHRMKDQK---NARPEDFAPMLATEGSV
TH_3391|M.thermoresistible__bu      TLHGEKISGRYALIQTDGKNWLAHKMKDQKPRTEIRPEDFTPMLATHGSV
Rv0938|M.tuberculosis_H37Rv         NLHGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTV
Mb0963|M.bovis_AF2122/97            NLHGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTV
MMAR_4573|M.marinum_M               NLHGSRISGRYALIQTNGDQWLAHRMK---DQTAFDFDTLAPMLTSHGSV
MUL_4434|M.ulcerans_Agy99           NLHGSRISGRYALIQTNGDQWLAHRMK---DQTAFDFDTLAPMLTSHGSV
MAV_1056|M.avium_104                NLHGRKISGRYALIQTEGDQWLAHRMK---DQNVFDFDTIAPMLATHGSV
MAB_1033|M.abscessus_ATCC_1997      TLHGKRITGRYALIRTNGKQWLVHRMKDQRPAGSMPVG-LAPMLPTTGSV
                                    .*** :: ******:*.*..**.*::*            ::***.: *:*

Mflv_1828|M.gilvum_PYR-GCK          ERLTRGQWAFEGKWDGYRLLVDADHGKLTLRSRRGRDVTAEYPQLKALAA
Mvan_4915|M.vanbaalenii_PYR-1       QRLTKGQWAFEGKWDGYRLLVEADHGRLALRSRNGRDVTAEYPQLQALAA
MSMEG_5570|M.smegmatis_MC2_155      AKYKAKQWAFEGKWDGYRVIIDADHGQLQIRSRTGREVTGEYPQFKALAA
TH_3391|M.thermoresistible__bu      ARLSAETHAFEGKWDGYRLLVHIDHGKLCLRSRSGRDVTKEFPTLQAMAA
Rv0938|M.tuberculosis_H37Rv         AGLKASQWAFEGKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAE
Mb0963|M.bovis_AF2122/97            AGLKASQWAFEGKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAE
MMAR_4573|M.marinum_M               AGLESGQWAFEGKWDGYRLLVEADHGALRLRSRSGRDVTAEYPQLRSLAA
MUL_4434|M.ulcerans_Agy99           AGLESGQWAFEGKWDGYRLLVEADHGALRLRSRSGRDVTTEYPQLRSLAA
MAV_1056|M.avium_104                SALKASQWAFEGKWDGYRLLVEADHGTLRVRSRRGREVTGEYRELRSLAK
MAB_1033|M.abscessus_ATCC_1997      AGLTAEEWAFEGKWDGYRLILECDRGQLRALARSGRDVTAEFPALQRLAH
                                            **********:::. *:* :   :* **:** *:  :: :* 

Mflv_1828|M.gilvum_PYR-GCK          DLADHHVILDGEAVALDEDGVPSFGEMQNRARSTRVEFWAFDILFLDGRL
Mvan_4915|M.vanbaalenii_PYR-1       DLADHHVILDGEAVALDESGVPSFREMQNRARSTRVEFWAFDILFLDGRS
MSMEG_5570|M.smegmatis_MC2_155      DLAEHHVVLDGEAVALDESGVPSFGQMQNRARSTRVEFWAFDILWLDGRS
TH_3391|M.thermoresistible__bu      DLADHQVVLDGEVVALDGSGVPSFGEMQNRARATHIEFWAFDILWLDGRS
Rv0938|M.tuberculosis_H37Rv         DLADHHVVLDGEAVVLDSSGVPSFSQMQNRGRDTRVEFWAFDLLYLDGRA
Mb0963|M.bovis_AF2122/97            DLADHHVVLDGEAVVLDSSGVPSFSQMQNRGRDTRVEFWAFDLLYLDGRA
MMAR_4573|M.marinum_M               DLADHHVVLDGELVALDSSGVPSFNEMQNRVRATRIEFWAFDLLFLDGRS
MUL_4434|M.ulcerans_Agy99           DLADHHVVLDGELVALDSSGVPSFNEMQNRVRATRIEFWAFDLLFLDGRS
MAV_1056|M.avium_104                ALEEHHAVLDGEAVVLDKRGVPNFHEMQNRGKSARVEFWAFDLLYLDGRS
MAB_1033|M.abscessus_ATCC_1997      ELSDHRVVLDGEVVVPDRKGLPSFALLQNRTPGADIRFWAFDLLYLDGKS
                                     * :*:.:**** *. *  *:*.*  :***   : :.*****:*:***: 

Mflv_1828|M.gilvum_PYR-GCK          LTKATYTDRRKLLEALAEG-GGLIVPPALEGD-GPEALEYARSQRWEGVI
Mvan_4915|M.vanbaalenii_PYR-1       LLRAKYTDRRRVLEALADG-GGLIVPPLIGADTGAEALETARKRGWEGVV
MSMEG_5570|M.smegmatis_MC2_155      LLRAKYSDRRKILEALADG-GGLIVPDQLPGD-GPEAMEHVRKKRFEGVV
TH_3391|M.thermoresistible__bu      LLRAKHSDRRRVLLALAEK-DGLIVPDLLPGDTGAEALEYARERGFEGVV
Rv0938|M.tuberculosis_H37Rv         LLGTRYQDRRKLLETLANA-TSLTVPELLPGD-GAQAFACSRKHGWEGVI
Mb0963|M.bovis_AF2122/97            LLGTRYQDRRKLLETLANA-TSLTVPELLPGD-GAQAFACSRKHGWEGVI
MMAR_4573|M.marinum_M               LLRARYRDRRKLLETLGSA-GNLIVPELLPGD-GAEALAYSHKRGWEGVI
MUL_4434|M.ulcerans_Agy99           LLRARYRDRRKLLETLGSA-GNLIVPELLPGD-GAEALAYSHKRGWEGVI
MAV_1056|M.avium_104                LLRARYRDRRKLLEMLASG-GDLTVPELLPGD-GDQALRQSAERGWEGVI
MAB_1033|M.abscessus_ATCC_1997      LLRTKYRDRRRLLEVLVTGTESMTVPQQLSGD-GAAALAYSQDQGWEGVV
                                    *  : : ***::*  *     .: **  : .* *  *:    .: :***:

Mflv_1828|M.gilvum_PYR-GCK          AKKRDSTYQPGRRSSAWIKDKIWNTQEVVIGGWRQGEGGRTSGIGALVLG
Mvan_4915|M.vanbaalenii_PYR-1       AKKRDSTYQPGRRSSSWIKDKLWNTQEVVIGGWRQGEGGRTSGIGALMLG
MSMEG_5570|M.smegmatis_MC2_155      AKKWDSTYQPGRRSSSWIKDKIWNTQEVVIGGWRQGEGGRSSGIGALVLG
TH_3391|M.thermoresistible__bu      AKRHDSIYQPGRRSKAWIKDKIWNMQEVVIGGWRKGEGGRSSGIGALVLG
Rv0938|M.tuberculosis_H37Rv         AKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGSLLMG
Mb0963|M.bovis_AF2122/97            AKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGSLLMG
MMAR_4573|M.marinum_M               AKRRDSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGSLLMG
MUL_4434|M.ulcerans_Agy99           AKRRDSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGSLLMG
MAV_1056|M.avium_104                AKRRDSTYQPGRRSSSWIKDKHWNTQEVVIGGWKAGEGGRSSGIGSLLMG
MAB_1033|M.abscessus_ATCC_1997      AKRLDSTYVPG-RTQSWIKAKNWSSQEVVIGGWRKGQGGRSSGIGSLLMG
                                    **: ** * ** *  :*:* * *. ********: *:***:**:*:*::*

Mflv_1828|M.gilvum_PYR-GCK          VPDD---DGLHFVGRVGTGFTDKQLASLKKTLEPLRTDESPFAAELPKQD
Mvan_4915|M.vanbaalenii_PYR-1       IPAGGVAGGLQFVGRVGTGFTEKELASLKETLAPLHTDESPFATELPKQD
MSMEG_5570|M.smegmatis_MC2_155      IPGP---EGLQFVGRVGTGFTEKELSKLKDMLKPLHTDESPFNAPLPKVD
TH_3391|M.thermoresistible__bu      IPTE---GGLQFVGRVGTGFTDKQLAELKQLLAPLETDESPFVDPLPRPD
Rv0938|M.tuberculosis_H37Rv         IPGP---GGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPLPARD
Mb0963|M.bovis_AF2122/97            IPGP---GGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPLPARD
MMAR_4573|M.marinum_M               IPGP---SGLHFAGRVGTGFTERDLANLKKTLAPLHTDESPFDAALPARE
MUL_4434|M.ulcerans_Agy99           IPGP---SGLHFAGRVGTGFTERDLANLKKTLAPLHTDESPFDAALPARE
MAV_1056|M.avium_104                IPGP---GGLHFAGRVGTGFTERDLANLKKTLAPLRTDQSPFDAPLPRSE
MAB_1033|M.abscessus_ATCC_1997      IPVE---GGLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPLSTVE
                                    :*      **::.******:::::*:.**. * **.  :***   *.  :

Mflv_1828|M.gilvum_PYR-GCK          AKGVTFVRPELVGEVRYSERTSDGRLRQASWRGLRDDKVPEDVRWEG-
Mvan_4915|M.vanbaalenii_PYR-1       AKGVTFVRPELVGEVRYSERTSDNRLRQPSWRGLRTDKTPDEVVWE--
MSMEG_5570|M.smegmatis_MC2_155      ARGVTFVRPELVGEVRYSERTSDGRLRQPSWRGLRPDKTPDEVVWE--
TH_3391|M.thermoresistible__bu      AKGVTYVRPELVGEVRYSERTADNRLRQPSWRGLRPDKSPDEVRWE--
Rv0938|M.tuberculosis_H37Rv         AKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE--
Mb0963|M.bovis_AF2122/97            AKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE--
MMAR_4573|M.marinum_M               AKGVTFVAPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE--
MUL_4434|M.ulcerans_Agy99           AKGVTFVVPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE--
MAV_1056|M.avium_104                AKGVTFVEPVLVGEVRYSEWTPDDRLRQSSWRGLRPDKEASEVVRE--
MAB_1033|M.abscessus_ATCC_1997      AKDVQFVEPVLVAEVRYGDRTPGGILKHSSWRGLRTDKSVRDVELDLG
                                    *:.: :* * **.****.: *. . *::.****** **   :*  :