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PAAAEELDVDGIAVRVTNRDKVYFPKLGKQGTKGRLIDYYLAVGGGPMLTALRDRPTHLQRFPDGIDGEE IYQKRVPKHHPDYLRTCQVTFPSGRTADALRVTHPAAIVWAAQMGTVTLHPWQVRCPDTEHPDELRIDLD PQPGTGFAQARSVAVDVLKPVLDDLGLVGYPKTSGGRGIHVFLRIASDWDFIEVRRAGIALAREVERRAP EAVTTSWWKEERGQRIFIDFNQNARDRTMASAYSVRATPIATVSTPLTWDELAGADPDDYTMATVADLIA RRADPWAGMDDVAQSISGLLDMAEADAERGLGDMPYPRNYPKMPGEPKRVQPSRDTDLKPKNAHD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4339 | - | - | 100% (346) | hypothetical protein MUL_4339 |
| M. ulcerans Agy99 | MUL_1190 | - | 2e-75 | 46.15% (325) | hypothetical protein MUL_1190 |
| M. ulcerans Agy99 | MUL_4434 | - | 1e-26 | 28.18% (291) | ATP-dependent DNA ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3757c | - | 1e-178 | 85.42% (343) | hypothetical protein Mb3757c |
| M. gilvum PYR-GCK | Mflv_1274 | - | 1e-161 | 79.40% (335) | DNA primase, small subunit |
| M. tuberculosis H37Rv | Rv3730c | - | 1e-178 | 85.42% (343) | hypothetical protein Rv3730c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0280 | - | 1e-140 | 77.78% (306) | hypothetical protein MAB_0280 |
| M. marinum M | MMAR_5265 | - | 0.0 | 97.67% (343) | hypothetical protein MMAR_5265 |
| M. avium 104 | MAV_0362 | ligD | 1e-179 | 86.80% (341) | DNA polymerase LigD polymerase subunit |
| M. smegmatis MC2 155 | MSMEG_6301 | ligD | 1e-165 | 79.70% (335) | DNA polymerase LigD polymerase subunit |
| M. thermoresistible (build 8) | TH_1676 | - | 1e-168 | 81.60% (337) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_5542 | - | 1e-161 | 78.51% (335) | hypothetical protein Mvan_5542 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4339|M.ulcerans_Agy99 ---MPAAAEELDVDGIAVRVTNRDKVYFPKLGKQG-TKGRLIDYYLAVGG
MMAR_5265|M.marinum_M ---MPAAAEELDVDGIAVRVTNRDKVYFPKLGKQG-TKGRLIDYYLAVGG
Mb3757c|M.bovis_AF2122/97 ---MAAAAEELDVDGIAVRLTSPDRMYFPKLGSHG-TKRRLVEYYFAVAG
Rv3730c|M.tuberculosis_H37Rv ---MAAAAEELDVDGIAVRLTSPDRMYFPKLGSHG-TKRRLVEYYFAVAG
MAV_0362|M.avium_104 ----MAAAEEVDVDGIAVRLTNPDKVYFPKLGSKG-TKRHLIDYYRAVAG
MAB_0280|M.abscessus_ATCC_1997 ---MPTPAEELDVDGIAVRLSNPDKVYFPRLGADGGTKRHLAEYYRTVAV
Mflv_1274|M.gilvum_PYR-GCK ---MPSPATELDVDGVKVRFTNPDKPYFPKLGKNG-TKGKLLEYYLAVAD
Mvan_5542|M.vanbaalenii_PYR-1 ---MPSPATEIDVDGVKVRLTSPDKPYFPKLGKDG-TKGKLFEYYLAVAD
MSMEG_6301|M.smegmatis_MC2_155 --MMASAATELDVDGVKVRFTNPDKVYFPKLGKNG-TKGKLVEYYLSVAS
TH_1676|M.thermoresistible__bu MAQKHGAATELDIDGVKVRLTSPDKVYFPKIGAAG-TKAALVDYYRSVSG
.* *:*:**: **.:. *: ***::* * ** * :** :*.
MUL_4339|M.ulcerans_Agy99 GPMLTALRDRPTHLQRFPDGIDGEEIYQKRVPKHHPDYLRTCQVTFPSGR
MMAR_5265|M.marinum_M GPMLTALRDRPTHLQRFPDGIDGEEIYQKRVPKHHPDYLRTCQVTFPSGR
Mb3757c|M.bovis_AF2122/97 GPMLTALRDRPTHLQRFPDGVDGEQIYQKRIPRHRPDYLQTCRVTFPSGR
Rv3730c|M.tuberculosis_H37Rv GPMLTALRDRPTHLQRFPDGVDGEQIYQKRIPRHRPDYLQTCRVTFPSGR
MAV_0362|M.avium_104 GPMLDALRDRPTHLQRFPDGIDGEEIYQKRIPQHHPDYLQTCRVTFPSGR
MAB_0280|M.abscessus_ATCC_1997 GPMLHALRDRPAHLQRFPDGIDGEEIYQKRLPKHYPDYLDSCEVTFPSGR
Mflv_1274|M.gilvum_PYR-GCK -PMVTLLRDRPVHLQRFPDGIDGEEIYQKRVPQKHPDYLETCTVTFPSGR
Mvan_5542|M.vanbaalenii_PYR-1 -RMVALLRDRPVHLQRFPDGIDGEEIYQKRVPQKHPDYLHTCTVTFPSGR
MSMEG_6301|M.smegmatis_MC2_155 GPMLALLRDRPVHLQRFPDGIEGEEIYQKRVPQKHPDYLETCVVTFPSGR
TH_1676|M.thermoresistible__bu -PMVALLRDRPTHLQRFPDGIEGEEIYQKRIPQRHPDYLQTCRVTFPSGR
*: *****.********::**:*****:*:: **** :* *******
MUL_4339|M.ulcerans_Agy99 TADALRVTHPAAIVWAAQMGTVTLHPWQVRCPDTEHPDELRIDLDPQPGT
MMAR_5265|M.marinum_M TADALQVTHPAAIVWAAQMGTVTLHPWQVRCPDTEHPDELRIDLDPQPGT
Mb3757c|M.bovis_AF2122/97 MADALKVTHPAAIVWAAQMGTITLHPWQVRCPDTEHPDELRIDLDPQPGT
Rv3730c|M.tuberculosis_H37Rv MADALKVTHPAAIVWAAQMGTITLHPWQVRCPDTEHPDELRIDLDPQPGT
MAV_0362|M.avium_104 TADALKVTHPAAIVWAAQMGTVTLHPWQVRCPETDHPDELRIDLDPQPGV
MAB_0280|M.abscessus_ATCC_1997 TAEVLRVTKPAAIVWAAQMGTVTLHPWQVRYPDLDHPDELRIDLDPQPGT
Mflv_1274|M.gilvum_PYR-GCK TADALKITHPSAIAWAAQMGTVTLHPWQVRCPDTEHPDELRIDLDPQPGT
Mvan_5542|M.vanbaalenii_PYR-1 TADALKITHPSAIAWAAQMGTVTLHPWQVRCPDIEHPDELRIDLDPQPGT
MSMEG_6301|M.smegmatis_MC2_155 TADALKITHPSSIIWAAQMGTVTLHPWQVRCPDTEHPDELRVDLDPQPGT
TH_1676|M.thermoresistible__bu TADALQITHPAAIVWAAQMSTITFHPWQVRCPDTEHPDELRIDLDPQPGT
*:.*::*:*::* *****.*:*:****** *: :******:*******.
MUL_4339|M.ulcerans_Agy99 GFAQARSVAVDVLKPVLDDLGLVGYPKTSGGRGIHVFLRIASDWDFIEVR
MMAR_5265|M.marinum_M GFAQARSVAVDVLKPVLDELGLVGYPKTSGGRGIHVFLRIATDWDFIEVR
Mb3757c|M.bovis_AF2122/97 GFVEARTVAVDVLRSVLDDLGLVGYPKTSGGRGIHVFLRIATDWDFVEVR
Rv3730c|M.tuberculosis_H37Rv GFVEARTVAVDVLRSVLDDLGLVGYPKTSGGRGIHVFLRIATDWDFVEVR
MAV_0362|M.avium_104 AFAQARSVAVDVLRPLLDELGLVGYPKTSGGRGIHVFLRIATDWDFVEVR
MAB_0280|M.abscessus_ATCC_1997 GFEEAKVVALEVLRPLLEELGLVAYPKTSGGRGIHVYLRIAARWDFIEVR
Mflv_1274|M.gilvum_PYR-GCK GFTEAADVAVGVLKPLLDELGLVGYPKTSGGRGVHVFLRIKTDWDFIAVR
Mvan_5542|M.vanbaalenii_PYR-1 GFIEARSVAVDVLKPLLDELGLVGFPKTSGGRGVHVFLRIATDWDFIAVR
MSMEG_6301|M.smegmatis_MC2_155 GFKEARTVACDVLKPLLDELGLVGYPKTSGGRGVHVFLRIKPQWDFIEVR
TH_1676|M.thermoresistible__bu GFAEARTVAVDVLKPLLDELGLTGYPKTSGGRGIHIFLRIATDWDFIEVR
.* :* ** **:.:*::***..:********:*::*** . ***: **
MUL_4339|M.ulcerans_Agy99 RAGIALAREVERRAPEAVTTSWWKEERGQRIFIDFNQNARDRTMASAYSV
MMAR_5265|M.marinum_M RAGIALAREVERRAPEAVTTSWWKEERGQRIFIDFNQNARDRTMASAYSV
Mb3757c|M.bovis_AF2122/97 RAGIALAREVERRAPDAVTTSWWKEERGARIFIDFNQNARDRTMASAYSV
Rv3730c|M.tuberculosis_H37Rv RAGIALAREVERRAPDAVTTSWWKEERGARIFIDFNQNARDRTMASAYSV
MAV_0362|M.avium_104 RAGIALAREVERRAPDAVTTSWWKEERGARIFIDFNQNARDRTMASAYSV
MAB_0280|M.abscessus_ATCC_1997 RAGIALAREVERRAPKQVTTSWWKEERGERIFIDFNQNARDRTMASAYSV
Mflv_1274|M.gilvum_PYR-GCK RAGIALAREVERRAPDAVTTSWWKEERGKRLFIDYNQNARDRTFASPYSA
Mvan_5542|M.vanbaalenii_PYR-1 RAGIALAREIERRAPDAVTTSWWKEERGARLFVDYNQNARDRTFASAYSA
MSMEG_6301|M.smegmatis_MC2_155 RAGIALAREVERRAPDAVTTSWWKEERGERLFIDYNQNARDRTFASAYSV
TH_1676|M.thermoresistible__bu RAGIALAREIERRAPDLVTTSWWKEERGERIFIDFNQNARDRTFASPYSV
*********:*****. *********** *:*:*:********:**.**.
MUL_4339|M.ulcerans_Agy99 RATPIATVSTPLTWDELAGADPDDYTMATVADLIARRADPWAGMDDVAQS
MMAR_5265|M.marinum_M RATPIATVSTPLTWDELAGADPDDYTMATVADLIARRADPWAGMDDVAQS
Mb3757c|M.bovis_AF2122/97 RPTPIATVSMPLTWEELAGADPDDYTMTTVPELVKIRDDPWAGMDDVAQS
Rv3730c|M.tuberculosis_H37Rv RPTPIATVSMPLTWEELAGADPDDYTMTTVPELVKIRDDPWAGMDDVAQS
MAV_0362|M.avium_104 RRTPIATVSMPLTWDQLAGADPDDYTMATVPDLVSARENPWAAIDDVAQS
MAB_0280|M.abscessus_ATCC_1997 RRTPIATVSTPVTWEELVDAEPDDFTIATVPALLRKRPDPMAGMDDAPQS
Mflv_1274|M.gilvum_PYR-GCK RKTPIATVSTPLTWEELRDAEPDDYTIQTVPDFIAGRPDPWAGIDDNAQS
Mvan_5542|M.vanbaalenii_PYR-1 RKTPIATVSTPLTWEELRTAEPDDYTILTVPDFVAGRPDPWAGIDDTAQS
MSMEG_6301|M.smegmatis_MC2_155 RKTPIATVSMPLSWDELRNADPDDYTMNTVPDLLAGRDDPWADIDSVQQS
TH_1676|M.thermoresistible__bu RKTPIATVSTPLSWDELRDADPDDYTMATVPDLIAARPDPWAGIDSVAHS
* ******* *::*::* *:***:*: **. :: * :* * :*. :*
MUL_4339|M.ulcerans_Agy99 ISGLLDMAEADAERGLGDMPYPRNYPKMPGEPKRVQPSRDTDLKPKNAHD
MMAR_5265|M.marinum_M ITGLLDMAEADAERGLGDMPYPPNYPKMPGEPKRVQPSRNTDLNRKNKPE
Mb3757c|M.bovis_AF2122/97 IAPLLDLAAADEERGLGDMPYPPNYPKMPGEPKRVQPSRDTDLKGGNTSK
Rv3730c|M.tuberculosis_H37Rv IAPLLDLAAADEERGLGDMPYPPNYPKMPGEPKRVQPSRDTDLKGGNTSK
MAV_0362|M.avium_104 IGPLLRMAEADEERGLGDMPYPPNYPKMPGEPKRVQPSRDTEHKKKN---
MAB_0280|M.abscessus_ATCC_1997 IEPLLEMVE-----------------------------------------
Mflv_1274|M.gilvum_PYR-GCK IDTLLEMVHADEERGEGDLPYPPSYPKMPGEPPRVQPSKKVAAHWDEHGN
Mvan_5542|M.vanbaalenii_PYR-1 IDTLLEMVKADEERGLGDLPYPPSYPKMPGEPPRVQPSKKVAANWDEDGN
MSMEG_6301|M.smegmatis_MC2_155 LGPLLDLVAADEERGLGDLPYPPNYPKMPGEPPRVQPSKKVAEHWDEQGN
TH_1676|M.thermoresistible__bu LEPLLAMAEADQERGLGDLPYPPNYPKMPGEPKRVQPSR------DTDRK
: ** :.
MUL_4339|M.ulcerans_Agy99 ----
MMAR_5265|M.marinum_M ----
Mb3757c|M.bovis_AF2122/97 ----
Rv3730c|M.tuberculosis_H37Rv ----
MAV_0362|M.avium_104 ----
MAB_0280|M.abscessus_ATCC_1997 ----
Mflv_1274|M.gilvum_PYR-GCK RIAD
Mvan_5542|M.vanbaalenii_PYR-1 RVGE
MSMEG_6301|M.smegmatis_MC2_155 RKQ-
TH_1676|M.thermoresistible__bu ET--