For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MDLDLDEETLAFQGEVREFLAANAEVMPTKSYDNAQGFAQHRVWDRVLFDAGLSVITWPKQYGGRDAPLL HWVIFEEEYFRAGAPGRASANGTSMLAPTLFAHGTAEQLDRILLKMASGEQIWAQTWSEPESGSDLASLR STATKTDGGWLLNGQKIWSSRAPFADMGFGLFRSDPSAQRHRGLTYFMFDLKAKGITVRPIVQLGGDTGF GEIFLDDVFVPDQDVIGAPNDGWRAAMSTSSNERGMSLRSPARFMAAAQKLVQLWKDAGSPPEFANRVAD AWIKAQAYRLQTFGTVTRLAAGGELGAGSSVTKVFWSDLDVDIHQTALDIRGADAELVSPWTEGLLFALG GPIYAGTNEIQRNIISERLLGLPREKK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4127 | fadE31 | - | 100% (377) | acyl-CoA dehydrogenase FadE31 |
| M. ulcerans Agy99 | MUL_4125 | fadE30 | 7e-63 | 37.01% (381) | acyl-CoA dehydrogenase FadE30 |
| M. ulcerans Agy99 | MUL_2892 | fadE17 | 2e-55 | 35.65% (359) | acyl-CoA dehydrogenase FadE17 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3592 | fadE31 | 0.0 | 89.89% (376) | acyl-CoA dehydrogenase FADE31 |
| M. gilvum PYR-GCK | Mflv_1479 | - | 1e-179 | 81.07% (375) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3562 | fadE31 | 0.0 | 89.89% (376) | acyl-CoA dehydrogenase FADE31 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 3e-20 | 25.30% (332) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0595c | - | 1e-163 | 72.53% (375) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_5051 | fadE31 | 0.0 | 99.47% (377) | acyl-CoA dehydrogenase FadE31 |
| M. avium 104 | MAV_0599 | - | 0.0 | 87.23% (376) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6014 | - | 0.0 | 82.93% (375) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_2586 | - | 1e-175 | 78.39% (384) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. vanbaalenii PYR-1 | Mvan_5287 | - | 1e-179 | 80.53% (375) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4127|M.ulcerans_Agy99 ----------MDLDLDEETLAFQGEVREFLAANAEVMPTKSYDNAQGFAQ
MMAR_5051|M.marinum_M ----------MDLDLDEETLAFQGEVREFLAANAEVMPTKSYDNAQGFAQ
Mb3592|M.bovis_AF2122/97 ----------MDLNFDDETLAFQAEVREFLAANAASIPTKSYDNAEGFAQ
Rv3562|M.tuberculosis_H37Rv ----------MDLNFDDETLAFQAEVREFLAANAASIPTKSYDNAEGFAQ
MAV_0599|M.avium_104 ----------MDLDLDEGTLAFRDEVRQFLSANAEAIPTKSYDNAEGFEQ
Mflv_1479|M.gilvum_PYR-GCK ----------MDLTFDDATLDFQAEVREFLAANKGSFPTKSYDTADGFEQ
Mvan_5287|M.vanbaalenii_PYR-1 ----------MDLTFDDATSEFRAEVRDFLAANKSAFPTKSYDTAEGFEQ
TH_2586|M.thermoresistible__bu ----------MDLHIDDATEEFRAEVREFLANNRKWFPTKSYDTAEGFEQ
MSMEG_6014|M.smegmatis_MC2_155 ----------MDLKFDEETEAFRAEVREFLAANRENFPTKSYDTKEGFEQ
MAB_0595c|M.abscessus_ATCC_199 ----------MDLLLDDETEAFRAEVREFLVSNVPNPPLPSYDSPEGAAA
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP---HAADVDQRARF
: : : :: :* : : : * :
MUL_4127|M.ulcerans_Agy99 HRVWDRVLFDAGLSVITWPKQYGGRDAPLLHWVIFEEEYFRAGAPGRASA
MMAR_5051|M.marinum_M HRVWDRVLFDAGLSVITWPKQYGGRDAPLLHWVIFEEEYFRAGAPGRASA
Mb3592|M.bovis_AF2122/97 HRYWDRVLFDAGLSVITWPAKYGGRDAPLLHWIVFEEEYFRAGAPGRASA
Rv3562|M.tuberculosis_H37Rv HRYWDRVLFDAGLSVITWPAKYGGRDAPLLHWIVFEEEYFRAGAPGRASA
MAV_0599|M.avium_104 HRRWDRVLYDAGLSVITWPKKYGGRDAPLLHWVVFEEEYFRAGAPGRASA
Mflv_1479|M.gilvum_PYR-GCK HRRWDKVLFDAGLSVITWPEKYGGRDASLLQWIVYEEEYFRAGAPGRASA
Mvan_5287|M.vanbaalenii_PYR-1 HRRWDKVLFDAGLSVITWPEKYGGRDASLLQWIVYEEEYFRAGAPGRASA
TH_2586|M.thermoresistible__bu HRQWDRVLYDARLSVITWPEKYGGRDATLLQWVVFEEEYFRAGAPGRASA
MSMEG_6014|M.smegmatis_MC2_155 HRRWDKALFDAGLSVIAWPKKYGGRDATLLQWVVFEEEYFRAGAPGRASA
MAB_0595c|M.abscessus_ATCC_199 HRQWERTLYDAGFSAVSWPKEYGGRDVTPLQWVIFEEEYFKAGAPARISQ
MLBr_00737|M.leprae_Br4923 PEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIP
. .* : :..: * :***:.. : : ** :..*..
MUL_4127|M.ulcerans_Agy99 NGTSMLAPTLFAHGTAEQLDRILLKMASGEQIWAQTWSEPESGSDLASLR
MMAR_5051|M.marinum_M NGTSMLAPTLFAHGTAEQLDRILLKMASGEQIWAQAWSEPESGSDLASLR
Mb3592|M.bovis_AF2122/97 NGTSMLAPTLFAHGTAEQLDRILPKMASGEQIWAQAWSEPESGSDLASLR
Rv3562|M.tuberculosis_H37Rv NGTSMLAPTLFAHGTAEQLDRILPKMASGEQIWAQAWSEPESGSDLASLR
MAV_0599|M.avium_104 NGTSMLAPTLFAHGTEEQRDRILPKMASGEEIWAQAWSEPESGSDLASLR
Mflv_1479|M.gilvum_PYR-GCK NGTSMLAPTLFAHGTEEQRDRILPKMASGEEIWAQAWSEPESGSDLASLR
Mvan_5287|M.vanbaalenii_PYR-1 NGTSMLAPTLFAHGTEEQLDRILPKMASGEEIWAQAWSEPESGSDLASLR
TH_2586|M.thermoresistible__bu NGTSMLAPTLFAHGTEEQLDRVLPKMATGEEIWAQAWSEPESGSDLASLR
MSMEG_6014|M.smegmatis_MC2_155 NGTSMLAPTLFAHGTSEQLDRVLPKMASGEEIWAQAWSEPESGSDLASLR
MAB_0595c|M.abscessus_ATCC_199 NGMFLLGPTLFAHGSKDQLDRVLPKMANGEEIWAQAWSEPESGSDLASLR
MLBr_00737|M.leprae_Br4923 AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
: *: :*: : .::* .:* : : : ** *:*** **:*
MUL_4127|M.ulcerans_Agy99 STATKTDGGWLLNGQKIWSSRAPFADMGFGLFRSDPSAQRHRGLTYFMFD
MMAR_5051|M.marinum_M STATKTDGGWLLNGQKIWSSRAPFADMGFGLFRSDPSAQRHRGLTYFMFD
Mb3592|M.bovis_AF2122/97 STASKVDGGWLLNGQKIWSSRAPFADMGFGLFRSDPAVERHRGLTYFMFD
Rv3562|M.tuberculosis_H37Rv STASKVDGGWLLNGQKIWSSRAPFADMGFGLFRSDPAVERHRGLTYFMFD
MAV_0599|M.avium_104 STATPTDGGWLLNGQKIWSSRAPFAERGFGLFRSDPSAERHHGLTYFMFD
Mflv_1479|M.gilvum_PYR-GCK STATRTEGGWLLNGQKIWSSRAVFGERAFGLFRSDPAAQRHKGLTYFMFD
Mvan_5287|M.vanbaalenii_PYR-1 STATRTDGGWLLNGQKIWSSRAVFGERAFGLFRSDPEAQRHKGLTYFMFD
TH_2586|M.thermoresistible__bu STATKTDGGWLLNGQKIWSSRAVFGERAFGLFRSDPQAQRHKGLTYFMFD
MSMEG_6014|M.smegmatis_MC2_155 STATKTDGGWLLNGQKIWSSRAVFGERGFGLFRSDPEAQRHKGLTYFMFD
MAB_0595c|M.abscessus_ATCC_199 SPARKVDGGWRLSGQKIWSSRAPFADRAFGLFRSDPDAQRHQGLTYFMFD
MLBr_00737|M.leprae_Br4923 TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDP-DKGANGISAFIVH
: * ..* *.* * * :.. . : :** : .*:: *:..
MUL_4127|M.ulcerans_Agy99 LKAKGITVRPIVQLGGDTG--FGEIFLDDVFVPDQDVIGAPNDGWRAAMS
MMAR_5051|M.marinum_M LKAKGITVRPIVQLGGDTG--FGEIFLDDVFVPDQDVIGAPNDGWRAAMS
Mb3592|M.bovis_AF2122/97 LKAKGVTVRPIAQLGGDTG--FGEIFLDDVFVPDRDVIGAPNDGWRAAMS
Rv3562|M.tuberculosis_H37Rv LKAKGVTVRPIAQLGGDTG--FGEIFLDDVFVPDRDVIGAPNDGWRAAMS
MAV_0599|M.avium_104 LKAEGVTVRPIVQLGGDTG--FGEIFLDDVFVPDRDVIGTPHQGWRAAMS
Mflv_1479|M.gilvum_PYR-GCK LKADGVTVRPIAQLGGDTG--FGEIFLDDVFVPDDDVIGEVHDGWRAAMS
Mvan_5287|M.vanbaalenii_PYR-1 LKAKGVTVRPIAQLGGDTG--FGEIFLDDVFVPDQDVIGGVHDGWRAAMS
TH_2586|M.thermoresistible__bu LRADGVTVRPIAQLGGDTG--FGEIFLDNVFVPDNDVIGEVNEGWRAAMS
MSMEG_6014|M.smegmatis_MC2_155 LKAQGVTVRPIAQLGGDTG--FGEIFFDDVFVPDNDVIGGVHDGWRAAMS
MAB_0595c|M.abscessus_ATCC_199 LKAEGITVRPIPQLDGDPG--FAEIFLDDVFVPDEDVIGAVHDGWRVAMS
MLBr_00737|M.leprae_Br4923 KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALA
.*.:: * : * * *:::*. :*. :** *::.*::
MUL_4127|M.ulcerans_Agy99 TSSNER--------GMSLRSPARFMAAAQKLVQLWKDAGSPPEFANRVAD
MMAR_5051|M.marinum_M TSSNER--------GMSLRSPARFMAAAQKLVQLWKDAGSPPEFANRVAD
Mb3592|M.bovis_AF2122/97 TSSNER--------GMSLRSPARFLASAERLVQLWKDRGSPPEFADRVAD
Rv3562|M.tuberculosis_H37Rv TSSNER--------GMSLRSPARFLASAERLVQLWKDRGSPPEFADRVAD
MAV_0599|M.avium_104 TSSNER--------GMSLRSPARFLATAERVVRLWQDRGSPAEFADRVAD
Mflv_1479|M.gilvum_PYR-GCK TSSNER--------GMSLRSPARFLAPAERLVAQWKDNPDP-VFTDRVAD
Mvan_5287|M.vanbaalenii_PYR-1 TSSNER--------GMSLRSPARFLAPAERLVAQWKDNPDP-AFTDRVAD
TH_2586|M.thermoresistible__bu TSSNER--------GMSLRSPARFLAPAERLVRLWKQNPDP-AFEERVAD
MSMEG_6014|M.smegmatis_MC2_155 TSSNER--------GMSLRSPARFLAPAERLVERWKENPDP-AFTDRVAD
MAB_0595c|M.abscessus_ATCC_199 TSSNER--------GMSLRSPGRFLATADRLVELWKSVPENEFASERVAD
MLBr_00737|M.leprae_Br4923 TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLAD
* .: * *:: : :. :. :. :**
MUL_4127|M.ulcerans_Agy99 AWIKAQAYRLQTFGTVTRLAAGG-ELGAGSSVTKVFWSDLDVDIHQTALD
MMAR_5051|M.marinum_M AWIKAQAYRLQTFGTVTRLAAGG-ELGAESSVTKVFWSDLDVDIHQTALD
Mb3592|M.bovis_AF2122/97 AWIKAQAYRLQTFGTVTRLAAGG-ELGAESSVTKVFWSELDVHLHQTALD
Rv3562|M.tuberculosis_H37Rv AWIKAQAYRLQTFGTVTRLAAGG-ELGAESSVTKVFWSELDVHLHQTALD
MAV_0599|M.avium_104 GWIKAQAYRLQTFGTVTRLAAGG-ELGAESSVTKVFWSDLDVELHQTALD
Mflv_1479|M.gilvum_PYR-GCK AWIKAQAYRLHTFGTVTRVAGGG-ELGAESSITKVFWSDLDVALHQTALD
Mvan_5287|M.vanbaalenii_PYR-1 AWIKAQAYRLHTFGTVTRVSNGG-ELGAESSITKVFWSELDVALHQTALD
TH_2586|M.thermoresistible__bu AWIKAQAYRLHTFGTVSRLARGG-ELGAESSVTKVFWSELDVALHQTALD
MSMEG_6014|M.smegmatis_MC2_155 AWIKAQAYRLHTFGTVTRLANGG-ELGAESSVTKVFWSDLDVALHQTALD
MAB_0595c|M.abscessus_ATCC_199 AWIAAQAYRLHTFGTVTRLAGGG-ELGAESSITKVFWSELDVALHETAID
MLBr_00737|M.leprae_Br4923 MAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQ
: .:* ** .:.:.:* * :** *: :* * *:: : : *::
MUL_4127|M.ulcerans_Agy99 IRGADAELVSPW---------TEGLLFALGGPIYAGTNEIQRNIISERLL
MMAR_5051|M.marinum_M IRGADAELVSPW---------TEGLLFALGGPIYAGTNEIQRNIISERLL
Mb3592|M.bovis_AF2122/97 LRGADGELAGPW---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
Rv3562|M.tuberculosis_H37Rv LRGADGELAGPW---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
MAV_0599|M.avium_104 ILAADGELAGPW---------TEGLLFALGGPIYAGTNEIQRNIISERLL
Mflv_1479|M.gilvum_PYR-GCK LRGADGELMDPV---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
Mvan_5287|M.vanbaalenii_PYR-1 LRGADGELTDSV---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
TH_2586|M.thermoresistible__bu LRGPDAELADSADRDEDGYSWTDGLLFALGGPIYAGTNEIQRNIIAERLL
MSMEG_6014|M.smegmatis_MC2_155 LAGADGELVGNW---------TEGLLFALGGPIYAGTNEIQRNIIAERLL
MAB_0595c|M.abscessus_ATCC_199 LRGAEGELTNAW---------TDGYLFSLGGPIYAGTNEIQRNIIAERIL
MLBr_00737|M.leprae_Br4923 LFGGAGYTSDFP--------VERFMRDAKITQIYEGTNQIQRVVMSRALL
: . . . : ** ***:*** :::. :*
MUL_4127|M.ulcerans_Agy99 GLPREKK---------
MMAR_5051|M.marinum_M GLPREKK---------
Mb3592|M.bovis_AF2122/97 GLPREKT---------
Rv3562|M.tuberculosis_H37Rv GLPREKT---------
MAV_0599|M.avium_104 GLPREKSGSKK-----
Mflv_1479|M.gilvum_PYR-GCK GLPRK-----------
Mvan_5287|M.vanbaalenii_PYR-1 GLPRK-----------
TH_2586|M.thermoresistible__bu GLPRK-----------
MSMEG_6014|M.smegmatis_MC2_155 GLPRESAGKSK-----
MAB_0595c|M.abscessus_ATCC_199 GLPRESSASARTGGAK
MLBr_00737|M.leprae_Br4923 R---------------