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AEELTDPAEGFAPLRIRRVVRETADAVSLVLDVPECCSHRFQYKAGQFLTLRVSVGGRDLRRCYSMSSAP VEDELRITVKRDPGGVVSNWINDTAAAGDELHAAPPEGRFTLTESDSSPRELVAFAGGSGITPIMSLVRA ALAGSDRTVKLFYANRGRDSVIFSEPLARLAEQHADRLTVEHHYDEDAGVVTASAVESFAARVGDADFYV CGPTPFMDTVETALLGAGVPKQRLHLERFTVAAAPDTVTDGDAQACEEVVIELQRQKVTAAYRQGDTLLQ TARLQGLKAPSSCETGSCGTCMARIVEGSARMLNNDALEPDEVEEGWVVTCQALPTSSKVHMIYE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4186 | - | - | 100% (346) | ferredoxin |
| M. vanbaalenii PYR-1 | Mvan_2893 | - | 3e-54 | 35.71% (336) | ferredoxin |
| M. vanbaalenii PYR-1 | Mvan_5309 | - | 3e-54 | 37.72% (342) | ferredoxin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3602 | hmp | 8e-58 | 39.53% (344) | hemoglobine-like protein |
| M. gilvum PYR-GCK | Mflv_2468 | - | 1e-160 | 80.35% (346) | ferredoxin |
| M. tuberculosis H37Rv | Rv3571 | hmp | 8e-58 | 39.53% (344) | hemoglobine-like protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0583c | - | 5e-61 | 37.21% (344) | putative oxidoreductase |
| M. marinum M | MMAR_5066 | hmp | 2e-56 | 38.37% (344) | flavodoxin reductase Hmp |
| M. avium 104 | MAV_3963 | - | 4e-80 | 57.98% (257) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0295 | - | 1e-117 | 61.38% (347) | oxidoreductase, FAD-binding |
| M. thermoresistible (build 8) | TH_2828 | - | 1e-122 | 64.06% (345) | PUTATIVE ferredoxin |
| M. ulcerans Agy99 | MUL_4142 | hmp | 5e-57 | 38.66% (344) | flavodoxin reductase Hmp |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4186|M.vanbaalenii_PYR-1 ----MAEELTDP----------AEGFAPLRIRRVVRETADAVSLVLDVPE
Mflv_2468|M.gilvum_PYR-GCK ----MVEELS------------VDGFAPLRIKRVVRETSDAVSLVLDVPE
TH_2828|M.thermoresistible__bu ----MSEETV--------------GFAPLRIKRVVRETRDAVSLVLDVPP
MSMEG_0295|M.smegmatis_MC2_155 ---MAAMETSTAPLDEPAGLTDADGFTPLRVKDVIRETTDAVSLILDVPE
MAV_3963|M.avium_104 ----MAEQRT--------------------------ATHDGP--------
Mb3602|M.bovis_AF2122/97 MTEAIGDEPLG------------DHVLELQIAEVVDETDEARSLVFAVPD
Rv3571|M.tuberculosis_H37Rv MTEAIGDEPLG------------DHVLELQIAEVVDETDEARSLVFAVPD
MMAR_5066|M.marinum_M MTDAIPDEPLG------------SHVLELQIAEVVAETDDARSLVFAVPD
MUL_4142|M.ulcerans_Agy99 MTDAIPDEPLG------------SHVLELQIAEVVAETDDARSLVFAVPD
MAB_0583c|M.abscessus_ATCC_199 ----MTDVPLG------------KHVLEVRIAEVIEETADSRSLVFEIPD
* :.
Mvan_4186|M.vanbaalenii_PYR-1 CCSH------RFQYKAGQFLTLRVSV-GGRDLRRCYSMSSAPVED-ELRI
Mflv_2468|M.gilvum_PYR-GCK DCSH------RFRYKAGQFLTVRVSV-DGRDLRRCYSMSSAPVEE-ELRI
TH_2828|M.thermoresistible__bu ECSD------RFRYRAGQFLTLQVEI-AGGRHRRCYSMSSSPHNGSDLQI
MSMEG_0295|M.smegmatis_MC2_155 LIED------RFRYTAGQFVTVKTTI-RGEEHRRCYSMSSSPHVGPDLRI
MAV_3963|M.avium_104 -------------------ATVTAPE-SGG--------------------
Mb3602|M.bovis_AF2122/97 GSDDPEIPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAV
Rv3571|M.tuberculosis_H37Rv GSDDPEIPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAV
MMAR_5066|M.marinum_M GSDDPRIPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTV
MUL_4142|M.ulcerans_Agy99 GSDDPRIPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTV
MAB_0583c|M.abscessus_ATCC_199 GAAD------KFAYAPGQYLTLRIPSDRTGSVARCYSLSSSPHLDDRLAV
*:
Mvan_4186|M.vanbaalenii_PYR-1 TVKRDPGGVVSNWINDTAAAGDELHAAPPEGRFTLTESDSSPRELVAFAG
Mflv_2468|M.gilvum_PYR-GCK TVKRDPGGLVSNWINDTAAEGDELHASPPEGRFTLAEGVSSPRPLIAFAG
TH_2828|M.thermoresistible__bu TVKRDPGGLVSNYLNDTAAAGVEIYASPPDGRFVLG---AADRDVVAFAG
MSMEG_0295|M.smegmatis_MC2_155 TVKRDRDGVVSNWINDTAAAGDRLLTAPPDGRFVLT---TADRDVVTFAG
MAV_3963|M.avium_104 --------------TDTAGPGGRLYALPPRGRFVLT---DTDRQLVAFAG
Mb3602|M.bovis_AF2122/97 TVKRTADGYASNWLCDHAQVGMRIHVLAPSGNFVPT---TLDADFLLLAA
Rv3571|M.tuberculosis_H37Rv TVKRTADGYASNWLCDHAQVGMRIHVLAPSGNFVPT---TLDADFLLLAA
MMAR_5066|M.marinum_M TVKRTADGYASNWLCDNAHQGMRIHVLAPSGNFVPK---TLDDDFLLLAA
MUL_4142|M.ulcerans_Agy99 TVKRTADGYASNWLCDNAHQGMRIHVLAPSGNFVPK---TLDDDFLLLAA
MAB_0583c|M.abscessus_ATCC_199 TVKRTADGYGSNWICDNAHAGMHMHVLAPSGVFVPK---QLDNDFLLLAG
* * * .: . .* * *. .: :*.
Mvan_4186|M.vanbaalenii_PYR-1 GSGITPIMSLVRAALAGSDRTVKLFYANRGRDSVIFSEPLARLAEQHADR
Mflv_2468|M.gilvum_PYR-GCK GSGITPIMSLVRAALADTARPVRLFYANRARGSVIFSEPLARLTEQHADR
TH_2828|M.thermoresistible__bu GSGITPVYSLIEYALATTDRRVKLFYANRSRDSVIFGAALEELVAAHPRR
MSMEG_0295|M.smegmatis_MC2_155 GSGVTPVFSLVNTTLATTGRRVRMFYANRDADSVIFRDALTRLTDSHSDR
MAV_3963|M.avium_104 GSGITPVFSLLRTALTAGTRRARLFYANRSRDAVIFDEDLADLQRRHAER
Mb3602|M.bovis_AF2122/97 GSGITPIMSICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDR
Rv3571|M.tuberculosis_H37Rv GSGITPIMSICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDR
MMAR_5066|M.marinum_M GSGITPIMSICKSTLAEGSGQVTLLYANRDERSVIFADALRELSAKYPDR
MUL_4142|M.ulcerans_Agy99 GSGITPIMSICKSALAEGGGQVTLLYANRDERSVIFADALRELSAKYPDR
MAB_0583c|M.abscessus_ATCC_199 GSGVTPMMAICKSALSQGSGKVVLIYANRDEQSVIFGAALRELAAKYPDR
***:**: :: . :*: . ::**** :*** * * :. *
Mvan_4186|M.vanbaalenii_PYR-1 LTVEHHYDEDAGVVTASAVESF--AARVG--DADFYVCGPTPFMDTVETA
Mflv_2468|M.gilvum_PYR-GCK LTVAHHFDEDAGVVTATAVASF--AESAG--DADYYICGPAPFMDTVEAS
TH_2828|M.thermoresistible__bu LSIVHHFDDESGVVRPAAVEAF--AEAVGGDGADFYICGPGPFMDTVEQT
MSMEG_0295|M.smegmatis_MC2_155 LHVHHHLDTRDGVVSARHITEFLGASTVSTAEADFYICGPAPFMDTVERV
MAV_3963|M.avium_104 FTLHHHLDDQRGFATQEDISAF--IATAG--DADFYVCGPNEFMDTVCTA
Mb3602|M.bovis_AF2122/97 LTVLHWLESLQGLPSASALAKL----VAPYTDRPVFICGPGPFMQAARDA
Rv3571|M.tuberculosis_H37Rv LTVLHWLESLQGLPSASALAKL----VAPYTDRPVFICGPGPFMQAARDA
MMAR_5066|M.marinum_M LTVVHWLESLQGLPSATALAQL----AAPFTGRTAFICGPGPFMEAARVA
MUL_4142|M.ulcerans_Agy99 LTVVHWLESLQGLPSATALAQL----AAPFTGRTAFICGPGPFMEAARVA
MAB_0583c|M.abscessus_ATCC_199 LTVIHWLESVQGLPSQQQLATL----TAPFAEHEAFICGPGPFMDASEAA
: : * : *. : : . ::*** **::
Mvan_4186|M.vanbaalenii_PYR-1 LLGAGVPKQRLHLERFTVAAAPDTVTDGDAQACE------EVVIELQRQK
Mflv_2468|M.gilvum_PYR-GCK LLDSGVPKQRLNLERFTIAEVPPGVTDNTDDACE------EIVIELDRQK
TH_2828|M.thermoresistible__bu LVNRGVPRDRLHLERFELTPASGAAIQ-AGEQTE------EVIIELDRKT
MSMEG_0295|M.smegmatis_MC2_155 LLDAGVPAQRVHLERFTVTPADP-AVEAESAATE------EVTIVLGRTT
MAV_3963|M.avium_104 LRDAGIAAERVHVEHFDVTDVGAAAPAEGQVQPG------EVTIVLDGAT
Mb3602|M.bovis_AF2122/97 LAALKVPAQQVHIEVFKSLESDPFAAVKVDDSGD--EAPATAVVELDGQT
Rv3571|M.tuberculosis_H37Rv LAALKVPAQQVHIEVFKSLESDPFAAVKVDDSGD--EAPATAVVELDGQT
MMAR_5066|M.marinum_M LQTLDVPAGQVHIEVFKSLESDPFAAVTVEDSAA--EPPATAVVELDGQT
MUL_4142|M.ulcerans_Agy99 LQTLDVPAGQVHIEVFKSLESDPFAAVTVEDSAA--EPPATAVVELDGQT
MAB_0583c|M.abscessus_ATCC_199 LKGNGMPHDRVHIEVFRSLESDPFAEVVLAEPSDDDEPPATATVELDGET
* :. ::::* * . : * .
Mvan_4186|M.vanbaalenii_PYR-1 VTAAYRQGDTLLQTARLQGLKAPSSCETGSCGTCMARIVEGSARMLNNDA
Mflv_2468|M.gilvum_PYR-GCK VTAAYRQGETLLQTARQKGLKAPASCETGSCGTCMARIVEGSARMRINDA
TH_2828|M.thermoresistible__bu TTAPYRSGNTLLQTARIAGLRAPSSCETGSCGTCMARLVAGSARMLNNDA
MSMEG_0295|M.smegmatis_MC2_155 VTQPYRAGTTLLQTARLAGLKAPSSCEVGTCGTCIGQVVEGSARLLNNDA
MAV_3963|M.avium_104 TTAPYQAGNTLLQTARMAGLRAPSSCEIGSCGTCMARLTQGSARMINNDA
Mb3602|M.bovis_AF2122/97 HTVSWPRTAKLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDV
Rv3571|M.tuberculosis_H37Rv HTVSWPRTAKLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDV
MMAR_5066|M.marinum_M HTVSWPRSAKLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDV
MUL_4142|M.ulcerans_Agy99 HTVSWPRSAKLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDV
MAB_0583c|M.abscessus_ATCC_199 HEVSWPRSTVLLDVLLAKGLDAPFSCREGHCMTCACVLKDGKVRMLVNDA
.: **:. ** ** **. * * :* : *...: **.
Mvan_4186|M.vanbaalenii_PYR-1 LEPDEVEEGWVVTCQALPTSSKVHMIYE-
Mflv_2468|M.gilvum_PYR-GCK LDEDEVEEGWVLTCQSLPTSRKVHVVYE-
TH_2828|M.thermoresistible__bu LDGDEVAEGWVLTCQALPTSRSVHVRYE-
MSMEG_0295|M.smegmatis_MC2_155 LDDDEIAEGWVVTCQALPTSHTVKVVYE-
MAV_3963|M.avium_104 LDPEEVDDGWVLTCQALPTSPTVRVVYE-
Mb3602|M.bovis_AF2122/97 LEQQDLDEGLILACQSRPESDSVEVTYDE
Rv3571|M.tuberculosis_H37Rv LEQQDLDEGLILACQSRPESDSVEVTYDE
MMAR_5066|M.marinum_M LEQQDLDDGLILACQSHPESDSVEVTYDE
MUL_4142|M.ulcerans_Agy99 LEQQDLDDGLILACQSHPESDSVEVTYDE
MAB_0583c|M.abscessus_ATCC_199 LSQNDIDDGYILACQAVPETDDVNVTFDE
*. ::: :* :::**: * : *.: ::