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VTDACQAEYAIAAMSTVEMDQAAPESAAHHPLPDPGESVPRLALPTIGIFLATLTAFVGSTTAYISGWIP FWVTIPVNAAVTFVMFTVVHDASHYAISSIRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQ DPDTFASHGSLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAIVTGNFWTLAIV FLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNRVGAEWLFTPVLLSQNYHLVHHLHPSVPFYRY LRTWRRNEEAYLERNAAISTVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVDP ITADATLVTFAVPEALRDAFRFEPGQHVTVRTDLGGQGIRRNYSICAPATRAQLRIAVKHIPGGAFSTFV ANELKAGDVLELMTPTGRFGTPLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKES TMFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTLRPAGVDEWFICGPLAMATA VRETLIEHGVDSERIHLELFYGFDTPPATRPSYAGATVTFTLSGQRAIFDLVPGDSILEGALGLRSDAPY ACMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAVDYDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3554 | fdxB | - | 100% (685) | POSSIBLE ELECTRON TRANSFER PROTEIN FDXB |
| M. tuberculosis H37Rv | Rv3571 | hmp | 2e-38 | 32.96% (358) | hemoglobine-like protein |
| M. tuberculosis H37Rv | Rv3230c | - | 5e-21 | 28.87% (291) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3584 | fdxB | 0.0 | 100.00% (685) | electron transfer protein FdxB |
| M. gilvum PYR-GCK | Mflv_2468 | - | 1e-45 | 32.84% (335) | ferredoxin |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0910 | - | 1e-72 | 43.27% (349) | putative phenylacetic acid degradation protein |
| M. marinum M | MMAR_5043 | fdxB | 0.0 | 86.18% (673) | electron transfer protein FdxB |
| M. avium 104 | MAV_0590 | - | 1e-38 | 32.31% (359) | oxidoreductase, electron transfer component |
| M. smegmatis MC2 155 | MSMEG_0295 | - | 2e-42 | 33.93% (336) | oxidoreductase, FAD-binding |
| M. thermoresistible (build 8) | TH_1743 | - | 6e-40 | 31.84% (358) | POSSIBLE HEMOGLOBINE-RELATED PROTEIN HMP |
| M. ulcerans Agy99 | MUL_4117 | fdxB | 0.0 | 84.99% (673) | electron transfer protein FdxB |
| M. vanbaalenii PYR-1 | Mvan_4186 | - | 1e-44 | 32.54% (335) | ferredoxin |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3554|M.tuberculosis_H37Rv MTDACQAEYAIAAMSTVEMD-QAAPESAAHHPLPDPGESVPRLALPTIGI
Mb3584|M.bovis_AF2122/97 MTDACQAEYAIAAMSTVEMD-QAAPESAAHHPLPDPGESVPRLALPTIGI
MMAR_5043|M.marinum_M -------------MSTIDAVNRAAPDSSAHHALPDPGETVPKLALPTLGI
MUL_4117|M.ulcerans_Agy99 -------------MSTIDAVNRAAPDSSAHHALPDAGETVPKLALPTLGI
MAB_0910|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_1743|M.thermoresistible__bu --------------------------------------------------
Rv3554|M.tuberculosis_H37Rv FLATLTAFVGSTTAYISGWIPFWVTIPVNAAVTFVMFTVVHDASHYAISS
Mb3584|M.bovis_AF2122/97 FLATLTAFVGSTTAYISGWIPFWVTIPVNAAVTFVMFTVVHDASHYAISS
MMAR_5043|M.marinum_M FLAALGSFVLTTVGYIDGWVPFWVTIPVNAAVTFVMFTVVHDASHYSVSS
MUL_4117|M.ulcerans_Agy99 FLAALGSFVLTTVGYIDGWVPSWVTIPVNAAVTFVMFTVVHYASHYSVSS
MAB_0910|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_1743|M.thermoresistible__bu --------------------------------------------------
Rv3554|M.tuberculosis_H37Rv IRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQDPDTFASHG
Mb3584|M.bovis_AF2122/97 IRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQDPDTFASHG
MMAR_5043|M.marinum_M VRWVNGLFGRLAFLFVGPVVAFPAFGYIHIQHHRHSNDDVEDPDTFASHG
MUL_4117|M.ulcerans_Agy99 VRWVNGLFGRLAFLFVGPVVAFPAFGYIHIQHHRHSNDDVEDPDTFASHG
MAB_0910|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_1743|M.thermoresistible__bu --------------------------------------------------
Rv3554|M.tuberculosis_H37Rv SLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAI
Mb3584|M.bovis_AF2122/97 SLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAI
MMAR_5043|M.marinum_M SPWLLPLRWSLVEYYYLKYYIPRARSRPVVEFAETLFMFALSITGLTIAI
MUL_4117|M.ulcerans_Agy99 SPWLLPLRWSLVEYYYLKYYIPRARSRPVVEFAETLFMFALSITGLTIAI
MAB_0910|M.abscessus_ATCC_1997 ------------------------------------------MTTELSAP
Mflv_2468|M.gilvum_PYR-GCK ------------------------------------------MVEELS--
Mvan_4186|M.vanbaalenii_PYR-1 ------------------------------------------MAEELTDP
MSMEG_0295|M.smegmatis_MC2_155 -----------------------------------------MAAMETSTA
MAV_0590|M.avium_104 ----------------------------------MTEADSAQALDEP---
TH_1743|M.thermoresistible__bu ------------------------------------------VTDEP---
Rv3554|M.tuberculosis_H37Rv VTGNFWTLAIVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNR
Mb3584|M.bovis_AF2122/97 VTGNFWTLAIVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNR
MMAR_5043|M.marinum_M VTGNFWTLAVVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRTNRYRATRNR
MUL_4117|M.ulcerans_Agy99 VTGNFWTLAVVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRTNRYRATRNR
MAB_0910|M.abscessus_ATCC_1997 TTG-----------------------------------------RGMRNR
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 PLDE----------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_1743|M.thermoresistible__bu --------------------------------------------------
Rv3554|M.tuberculosis_H37Rv VGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYLRTWRRNEEAYLERNAAIS
Mb3584|M.bovis_AF2122/97 VGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYLRTWRRNEEAYLERNAAIS
MMAR_5043|M.marinum_M VGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYVRTWKRNEEAYLERNAAIS
MUL_4117|M.ulcerans_Agy99 VGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYVRTWKRNEEAYLERNAAIS
MAB_0910|M.abscessus_ATCC_1997 P---------------------------FRTVR-----------------
Mflv_2468|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4186|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0295|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
TH_1743|M.thermoresistible__bu --------------------------------------------------
Rv3554|M.tuberculosis_H37Rv TVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVD
Mb3584|M.bovis_AF2122/97 TVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVD
MMAR_5043|M.marinum_M TVFGQQLNPDEYRQWKELNGRLAKLLPVRMPARSSSPHAVLHRIPVASVD
MUL_4117|M.ulcerans_Agy99 TVFGQQLNPDEYREWKELNGRLAKLLPVRMPVRSSSPHAVLHRIPVASVD
MAB_0910|M.abscessus_ATCC_1997 ---------------------------------------------VAEVQ
Mflv_2468|M.gilvum_PYR-GCK -------------------------------------VDGFAPLRIKRVV
Mvan_4186|M.vanbaalenii_PYR-1 -------------------------------------AEGFAPLRIRRVV
MSMEG_0295|M.smegmatis_MC2_155 -------------------------------PAGLTDADGFTPLRVKDVI
MAV_0590|M.avium_104 ------------------------------------LGDHVLELQIAEVI
TH_1743|M.thermoresistible__bu ------------------------------------LGSHVLELQVAEVV
: *
Rv3554|M.tuberculosis_H37Rv PITADATLVTFAVPEA------LRDAFRFEPGQHVTVRTDLGGQ-GIRRN
Mb3584|M.bovis_AF2122/97 PITADATLVTFAVPEA------LRDAFRFEPGQHVTVRTDLGGQ-GIRRN
MMAR_5043|M.marinum_M PITTDSTLVTFAVPED------LQDAFRFEPGQHVTVRTDLGGQ-GVRRN
MUL_4117|M.ulcerans_Agy99 PITTDSTLVTFAVPED------LQDAFRFEPGQHVTVRTDLGGQ-GVRRN
MAB_0910|M.abscessus_ATCC_1997 QLCADAAAITFAVPDQ------YIDEFGFAPGQSITVRRNVDGV-EQRRT
Mflv_2468|M.gilvum_PYR-GCK RETSDAVSLVLDVPED------CSHRFRYKAGQFLTVRVSVDGR-DLRRC
Mvan_4186|M.vanbaalenii_PYR-1 RETADAVSLVLDVPEC------CSHRFQYKAGQFLTLRVSVGGR-DLRRC
MSMEG_0295|M.smegmatis_MC2_155 RETTDAVSLILDVPEL------IEDRFRYTAGQFVTVKTTIRGE-EHRRC
MAV_0590|M.avium_104 AETDDARSLVFAVPDDDGDPDIPPERLRYAPGQFLTLRVPSERTGSVARC
TH_1743|M.thermoresistible__bu EETADARSLVFTVPDG---VDIPPERLRYAPGQFLTLRVPSDRTGSVARC
*: : : **: . : : .** :*:: *
Rv3554|M.tuberculosis_H37Rv YSI-CAPATRAQLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGT
Mb3584|M.bovis_AF2122/97 YSI-CAPATRAQLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGT
MMAR_5043|M.marinum_M YSI-CAPATRAQLRIAVKHIPGGAFSTFVANDLKAGDVLELMTPTGQFGT
MUL_4117|M.ulcerans_Agy99 YSI-CAPATRAQLRIAVKHIPGGAFSTFVANDRKAGDVLELMTPTGQFGT
MAB_0910|M.abscessus_ATCC_1997 YSI-CSPLG-ARPRIGVREVPGGACSGWLVHQLSAGDEIEVQPPSGNF--
Mflv_2468|M.gilvum_PYR-GCK YSMSSAP-VEEELRITVKRDPGGLVSNWINDTAAEGDELHASPPEGRFTL
Mvan_4186|M.vanbaalenii_PYR-1 YSMSSAP-VEDELRITVKRDPGGVVSNWINDTAAAGDELHAAPPEGRFTL
MSMEG_0295|M.smegmatis_MC2_155 YSMSSSPHVGPDLRITVKRDRDGVVSNWINDTAAAGDRLLTAPPDGRFVL
MAV_0590|M.avium_104 YSLCSSPFTDDALTVTVKRTADGYASNWLCDNARPGMRIHVLAPSGNFVP
TH_1743|M.thermoresistible__bu YSLCSSPFTGDPMTVTVKRTEDGYASNWLCDNAHPGMRIHVLAPSGTFVP
**: .:* : *:. .* * :: . * : .* * *
Rv3554|M.tuberculosis_H37Rv PLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKEST
Mb3584|M.bovis_AF2122/97 PLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKEST
MMAR_5043|M.marinum_M PLNPLERKHYVGLVAGSGITPVLSILATTLEIEAESRFTLIYGNRTKEST
MUL_4117|M.ulcerans_Agy99 PLNPLERKHYVGLVAGSGTTPVLSILATTLEIEAESRFTLIYGNRTKEST
MAB_0910|M.abscessus_ATCC_1997 VADATTPAHHVLIAAGSGITPLLSIAASVLAQP-DSRVTLLYGNRRANTV
Mflv_2468|M.gilvum_PYR-GCK AEGVSSPRPLIAFAGGSGITPIMSLVRAALADT-ARPVRLFYANRARGSV
Mvan_4186|M.vanbaalenii_PYR-1 TESDSSPRELVAFAGGSGITPIMSLVRAALAGS-DRTVKLFYANRGRDSV
MSMEG_0295|M.smegmatis_MC2_155 T---TADRDVVTFAGGSGVTPVFSLVNTTLATT-GRRVRMFYANRDADSV
MAV_0590|M.avium_104 K---TLGDDFLLMAAGSGITPIMSIAKSALSEG-SGRVTLLYANRDERSV
TH_1743|M.thermoresistible__bu K---SLDADFLLLAAGSGITPMMAICKSALAEG-SGQVVLVYANRDENSV
: :..*** **:::: :.* . :.*.** :.
Rv3554|M.tuberculosis_H37Rv MFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTL
Mb3584|M.bovis_AF2122/97 MFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTL
MMAR_5043|M.marinum_M MFRAELDRLESRYADRLEILHVMSNEPLHTPELRGRIDTEKLNRWLTSNL
MUL_4117|M.ulcerans_Agy99 MFRAELDRLESRYADRLEILHVMSNEPLHTPELRGRIDTEKLNRWLTSNL
MAB_0910|M.abscessus_ATCC_1997 MFADELADLKDTYHSRLQLVHVLSREPRTVELFSGRLDHQRIRVLLQQLV
Mflv_2468|M.gilvum_PYR-GCK IFSEPLARLTEQHADRLTVAHHFDED-------AGVVTATAVASFAES--
Mvan_4186|M.vanbaalenii_PYR-1 IFSEPLARLAEQHADRLTVEHHYDED-------AGVVTASAVESFAAR--
MSMEG_0295|M.smegmatis_MC2_155 IFRDALTRLTDSHSDRLHVHHHLDTR-------DGVVSARHITEFLGAST
MAV_0590|M.avium_104 IFADALRELSAKYPDRLTVLHWLESL-------QGLPSVTALAQLAAP--
TH_1743|M.thermoresistible__bu IFSAALRDLAAKYPDRLTVVHWLESV-------QGLPTVAALTGLVRP--
:* * * : .** : * . * :
Rv3554|M.tuberculosis_H37Rv RPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYGFDTPPATRP
Mb3584|M.bovis_AF2122/97 RPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYGFDTPPATRP
MMAR_5043|M.marinum_M SPETVDEWFICGPMEMTTTVRDSLIEHGVDTEHIHLELFFGYNTAPATDH
MUL_4117|M.ulcerans_Agy99 SPETVDEWFICGPMEMTTTVRDSLIEHGVDTEHIHLELFFGYNTAPATDH
MAB_0910|M.abscessus_ATCC_1997 PIAAVDHVWLCGPFGMVTDAQAALRELGVEDSRIHQELFFVEDAAPPQAE
Mflv_2468|M.gilvum_PYR-GCK --AGDADYYICGPAPFMDTVEASLLDSGVPKQRLNLERFTIAEVPPGVTD
Mvan_4186|M.vanbaalenii_PYR-1 --VGDADFYVCGPTPFMDTVETALLGAGVPKQRLHLERFTVAAAPDTVTD
MSMEG_0295|M.smegmatis_MC2_155 VSTAEADFYICGPAPFMDTVERVLLDAGVPAQRVHLERFTVTPADP-AVE
MAV_0590|M.avium_104 --YTDRPVYICGPGAFMDSAREALETLKVPAAQIHIEVFKSLDSDPFAAV
TH_1743|M.thermoresistible__bu --YAAHDAFICGPAPFMAAAEEALTNVGAPADRIHIEVFKSLESDPFATV
::*** : .. * . ::: * *
Rv3554|M.tuberculosis_H37Rv SYAGAT----------VTFTLSGQRAIFDLVPGDSILEGALGLRSDAPYA
Mb3584|M.bovis_AF2122/97 SYAGAT----------VTFTLSGQRAIFDLVPGDSILEGALGLRSDAPYA
MMAR_5043|M.marinum_M GYEGAT----------VTFTLSGRQDTFDLTPGDSILEGALQRRSDAPYA
MUL_4117|M.ulcerans_Agy99 GYEGAT----------VTFTLSGRQDTFDLTPGDSILEVALQRRSDAPYA
MAB_0910|M.abscessus_ATCC_1997 HRDGVAS----GPVSEVTIVLDGATSTMALPRNVSVLDAAQRSRDDLPFA
Mflv_2468|M.gilvum_PYR-GCK NT--------DDACEEIVIELDRQKVTAAYRQGETLLQTARQKGLKAPAS
Mvan_4186|M.vanbaalenii_PYR-1 GD--------AQACEEVVIELQRQKVTAAYRQGDTLLQTARLQGLKAPSS
MSMEG_0295|M.smegmatis_MC2_155 AE--------SAATEEVTIVLGRTTVTQPYRAGTTLLQTARLAGLKAPSS
MAV_0590|M.avium_104 KI--EDTAEGDEPPATAVVELDGETHTVSWPRNAKLLDVLLAKGLDAPFS
TH_1743|M.thermoresistible__bu VVDYDEAGEGGEGPATAIVTLDGQTHEVTWPRSAKLLDVLLDKGLDAPFS
. * . .:*: . * :
Rv3554|M.tuberculosis_H37Rv CMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAV
Mb3584|M.bovis_AF2122/97 CMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAV
MMAR_5043|M.marinum_M CMGGACGTCRAKLIEGNVEMDHNFALGQAELDAGYILTCQSHPTTPFVAV
MUL_4117|M.ulcerans_Agy99 CMGGACGTCRAKLIEGNVEMDHNFALGQAELDAGYILTCQSHPTTPFVAV
MAB_0910|M.abscessus_ATCC_1997 CKGGVCGTCRAKVTGGAVDMRRNYALEPDEIDAGFVLTCQSYPTTDSLTV
Mflv_2468|M.gilvum_PYR-GCK CETGSCGTCMARIVEGSARMRINDALDEDEVEEGWVLTCQSLPTSRKVHV
Mvan_4186|M.vanbaalenii_PYR-1 CETGSCGTCMARIVEGSARMLNNDALEPDEVEEGWVVTCQALPTSSKVHM
MSMEG_0295|M.smegmatis_MC2_155 CEVGTCGTCIGQVVEGSARLLNNDALDDDEIAEGWVVTCQALPTSHTVKV
MAV_0590|M.avium_104 CREGHCGACACTLRKGQVSMEVNDVLEQQDLDEGLILACQSHPESDSVEV
TH_1743|M.thermoresistible__bu CREGHCGACAVVKKSGEVEMEVNDVLEQSDLDEGLILGCQARPLSDSVEV
* * **:* * . : * .* :: * :: **: * : : :
Rv3554|M.tuberculosis_H37Rv DYDA
Mb3584|M.bovis_AF2122/97 DYDA
MMAR_5043|M.marinum_M DYDS
MUL_4117|M.ulcerans_Agy99 DYDS
MAB_0910|M.abscessus_ATCC_1997 DFDA
Mflv_2468|M.gilvum_PYR-GCK VYE-
Mvan_4186|M.vanbaalenii_PYR-1 IYE-
MSMEG_0295|M.smegmatis_MC2_155 VYE-
MAV_0590|M.avium_104 TYDD
TH_1743|M.thermoresistible__bu TYDE
::