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AVPFLGSEAVAGGEVRKSALRTRYHRLFPDVYIRCDAELSPQARARAGWLWSRRRGIVTGLSASALHGAR WVDPDAPLDILHVNRNPRPGIRARGDRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDSLMRA ADVGRAQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLLLLDDGLPRPQTQIRVADEWGELVA YLDMGWEELMVAVEYDGEQHRNDRRQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4100 | - | - | 100% (237) | hypothetical protein MUL_4100 |
| M. ulcerans Agy99 | MUL_4737 | - | 4e-58 | 47.21% (233) | hypothetical protein MUL_4737 |
| M. ulcerans Agy99 | MUL_2811 | - | 1e-54 | 44.73% (237) | hypothetical protein MUL_2811 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3546 | - | 2e-71 | 54.51% (233) | hypothetical protein Mb3546 |
| M. gilvum PYR-GCK | Mflv_4708 | - | 2e-60 | 48.94% (235) | hypothetical protein Mflv_4708 |
| M. tuberculosis H37Rv | Rv3517 | - | 2e-71 | 54.51% (233) | hypothetical protein Rv3517 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1570 | - | 2e-67 | 54.85% (237) | hypothetical protein MAB_1570 |
| M. marinum M | MMAR_5026 | - | 1e-137 | 98.73% (237) | hypothetical protein MMAR_5026 |
| M. avium 104 | MAV_3351 | - | 6e-90 | 66.67% (237) | hypothetical protein MAV_3351 |
| M. smegmatis MC2 155 | MSMEG_5917 | - | 5e-65 | 49.79% (237) | hypothetical protein MSMEG_5917 |
| M. thermoresistible (build 8) | TH_1775 | - | 6e-63 | 50.21% (233) | conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_1656 | - | 2e-54 | 46.12% (232) | hypothetical protein Mvan_1656 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4100|M.ulcerans_Agy99 ----MAVPFLGSEAVAGGEVRKSALRTRYHRLFPDVYIRCDAELSPQARA
MMAR_5026|M.marinum_M ----MAVPFLGSEAVASGEVRKSALRTRYHRLFPDVYIRCDAELSPQARA
MAV_3351|M.avium_104 ----MVEPFIGSEAVADGEVVKSALRTRYKRLFRDVYIHPGAELSALTRA
MAB_1570|M.abscessus_ATCC_1997 ----MGEPFVGSEAVRSGRLTAYALRTRYVAIHPDVYLPRGAQLTPLVRA
Mb3546|M.bovis_AF2122/97 ----MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRA
Rv3517|M.tuberculosis_H37Rv ----MIEPFLGSEAIASGALTRHRLRSAYATIHPDVYVSPGADLTAWSRA
Mflv_4708|M.gilvum_PYR-GCK ----MGEPFIGSEALRAGRLTRHQLRTAHIAVYPDVYVPVATTLTAVAKA
MSMEG_5917|M.smegmatis_MC2_155 ----MGDPVIGTEAVAAGFATPYQLRSRYWPVYPGIYVPKDTQPTAALRA
TH_1775|M.thermoresistible__bu MAAPFSEPFLGSEALTSGALTRHQLRTRYRAIHRDVYIANDAELDAVLRA
Mvan_1656|M.vanbaalenii_PYR-1 ----MGRVFIGSEALAAGALTRSALRWNYRRILPDVYVPAASQLSLRDRT
: .:*:**: * ** : : .:*: : ::
MUL_4100|M.ulcerans_Agy99 RAGWLWSRRRGIVTGLSASALHGARWVDPDAPLDILHVNRNPRPGIRARG
MMAR_5026|M.marinum_M RAGWLWSRRRGIVAGLAASALHGARWVDPDAPLDILHVNRNPRPGIRARG
MAV_3351|M.avium_104 RAGWLWSRRRGVIAGLSAAAVHGARWVDATAPLEILHSNRNPLPGLRIHS
MAB_1570|M.abscessus_ATCC_1997 QASWLWTGRRGILAGHSASALHGARWIDAARNAEIVHDNRHRQPGITVWS
Mb3546|M.bovis_AF2122/97 QAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWS
Rv3517|M.tuberculosis_H37Rv QAAWLWSRRRGVIAGQSAAAMHGAKWVDARQAAELLYDHRRPPAGIHTWS
Mflv_4708|M.gilvum_PYR-GCK KAASLWTGREGIIAGQSAAAIHGARWVDARRPAEVLWHNRRAPRGVLVWS
MSMEG_5917|M.smegmatis_MC2_155 KAAWLWSDRRAVLAGRSASALHRSRWLDPRAPAELIHDNRRPPCGIKTWL
TH_1775|M.thermoresistible__bu KACWLRSRGHGVLAGFSASALHGAKYVDPRRPATVIDTNRRRTPGILTWG
Mvan_1656|M.vanbaalenii_PYR-1 IAAWLWSGRGAVVAGAAAAALHGAKWVDAEVPIELIWRCGRPPPGVVVRN
* * : .:::* :*:*:* ::::*. :: . *:
MUL_4100|M.ulcerans_Agy99 DRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDSLMRAADVGR
MMAR_5026|M.marinum_M DRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDSLMRAADVGR
MAV_3351|M.avium_104 DRLESDEYALVDGVPVTTPARTAVDLGCWHPVNDAVAVIDDLLRATDCKV
MAB_1570|M.abscessus_ATCC_1997 GEIAPDEICVVRGMRATTAARTALDLACRCPRGRAVAAIDALCRATELQI
Mb3546|M.bovis_AF2122/97 DRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKL
Rv3517|M.tuberculosis_H37Rv DRVADDEIQPISGMNTTTPARTALDLARRYPVGKAVAAIDALARATDLKL
Mflv_4708|M.gilvum_PYR-GCK DRVADDEVTTVRGVRVTTPERTALDIACRYPQRRAVAAIDALARAAHMKL
MSMEG_5917|M.smegmatis_MC2_155 DRFEDDEITVVDGIRVTTPARTAVDLACRYPLDTAVTLIDALGNATRLKM
TH_1775|M.thermoresistible__bu HTLDEDEICEIDGMRLTTPARTAVDLACRYPVGTSVAAIDALARAARLKV
Mvan_1656|M.vanbaalenii_PYR-1 ERIDGDEVTGVAGMLVTTPERTAFDLARHLRRNPAVARLDALANATDVKA
. ** : *: **. ***.*:. :*: :* * .*:
MUL_4100|M.ulcerans_Agy99 AQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLLLLDDGLPRP
MMAR_5026|M.marinum_M AQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLLLLDDGLPRP
MAV_3351|M.avium_104 AECQLLADRYPGRRGMQSARAAIGLADAGAQSPKETWLRLLLIRAGLPRP
MAB_1570|M.abscessus_ATCC_1997 SEALELASRHAGMRGIRRARTAFELVDAGAQSPKETWLRLLLRDAGLPPV
Mb3546|M.bovis_AF2122/97 ADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRP
Rv3517|M.tuberculosis_H37Rv ADVEMLAERYRGSRGIRNARIALDLVDPGAESPRETWLRLLLIRAGFPRP
Mflv_4708|M.gilvum_PYR-GCK ADVELLVDRHTGRRGIRAARAALNLVDPGAESPQETYLRLTVIGNHFPPP
MSMEG_5917|M.smegmatis_MC2_155 ADVELLVDRYRGRRGIKNARHVLDLVDGGAESPRETWLRLEVIRGGFPRP
TH_1775|M.thermoresistible__bu ADIEAAAQRHPGRHGLRRAREAIALVDPGAESPRETALRLLIVRAGYPPP
Mvan_1656|M.vanbaalenii_PYR-1 VDVLTLAQRYPGARGMRRAVKSLSLMDGGAQSPRESRLRLLLVDTWLDPV
: *: : :: * . * **:**:*: *** :
MUL_4100|M.ulcerans_Agy99 QTQIRVADEWGELVAYLDMGWEELMVAVEYDGEQHRNDRRQ---------
MMAR_5026|M.marinum_M QTQIRVADEWGELVAYLDMGWEELMVAVEYDGEQHRNDRRQYSWDIRRKE
MAV_3351|M.avium_104 QTQIPVSDEFGGVTYYLDMGWEDFMVAAEYDGEQHRRDRWQYTWDIRRRE
MAB_1570|M.abscessus_ATCC_1997 STQILVHNGDFVALAYIDMGWEDVMVGIEYDGDQHRSDRRQYLKDIRRLE
Mb3546|M.bovis_AF2122/97 QTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAE
Rv3517|M.tuberculosis_H37Rv QTQIPVYDEYGQLVAVIDMGWAGIKVGVDYEGDHHRTDRRTFNKDIKRAE
Mflv_4708|M.gilvum_PYR-GCK QTQIPVWD-CGALVAELDMGWEHMMIGLDYEGDHHRTTREAFNKGIRRHD
MSMEG_5917|M.smegmatis_MC2_155 QTQIPVHDEYGVLVGVFDMGWEDAMVGLDYEGDQHRTDRRRFNRDIHKSE
TH_1775|M.thermoresistible__bu ETQLPIHNEFGVLIGVVDMGWRDRRIAVEYEGRHHFTSRRAINRDIRRHD
Mvan_1656|M.vanbaalenii_PYR-1 RTQIKVGE--GRDVAYLDMGYDEPMIGLDYEGAHHNEDRKTYVYDIGRAE
**: : : .***: :. :*:* :* *
MUL_4100|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5026|M.marinum_M ILERLGWTVIRVLAGDRPTDILRRVRAALVRRASR---------------
MAV_3351|M.avium_104 TLERLGWIVIQVVAGDRPADIVSRVSAALARRGVTLA-------------
MAB_1570|M.abscessus_ATCC_1997 MLEGMGWLIVRVVAEDHPHDIIRRVREALARRV-----------------
Mb3546|M.bovis_AF2122/97 ALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------------
Rv3517|M.tuberculosis_H37Rv ALTELGWTDVRVTVEDTEGGIIWRVSAAWQRRT-----------------
Mflv_4708|M.gilvum_PYR-GCK AVTELGWTDIRVTCNDTEGAIIARLTTAWRQRLCALGENPDAGPPWTHVR
MSMEG_5917|M.smegmatis_MC2_155 DVRRLGWTHIRVTAQDGEADILKRIEAAGVPRGPRV--------------
TH_1775|M.thermoresistible__bu DMLEMGWTVLRVTAADTDGGFLRRLETAWSRPAEHSPAQHSPAQRSPAQR
Mvan_1656|M.vanbaalenii_PYR-1 RIESRGWIDIKVVKEHSSEFIQARVTEAFARRGYTPRLRPLPRKRRRRRP
MUL_4100|M.ulcerans_Agy99 ------
MMAR_5026|M.marinum_M ------
MAV_3351|M.avium_104 ------
MAB_1570|M.abscessus_ATCC_1997 ------
Mb3546|M.bovis_AF2122/97 ------
Rv3517|M.tuberculosis_H37Rv ------
Mflv_4708|M.gilvum_PYR-GCK RQRPGQ
MSMEG_5917|M.smegmatis_MC2_155 ------
TH_1775|M.thermoresistible__bu S-----
Mvan_1656|M.vanbaalenii_PYR-1 ------