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M. ulcerans Agy99 MUL_3388 (pgsA3)

annotation: PGP synthase PgsA3
coordinates: 3756738 - 3757406
length: 222

TFGHEKTVSTSAAGRLVNRYSVAVSGQPQTGQVPGTVGIANLANVLTGLRFVLVPIFLYLLFYDGGHQTT
FRIAAWAVFAVASITDRFDGLLARNYGMATEFGAFVDPIADKALIGAALIGLSMLNDLPWWVTVLILSRE
LGVTMLRLAVIRRGVIPASWGGKLKTVVQAVAIGLFVLPLSGPLHMAAVVVMAAAIVLTVVTGIDYVAST
VREIRAGKRAS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_3388pgsA3-100% (222)PGP synthase PgsA3
M. ulcerans Agy99MUL_3041pgsA24e-1126.15% (130) CDP-diacylglycerol--glycerol-3-phosphate 3-

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2767cpgsA33e-8880.61% (196) CDP-diacylglycerol--glycerol-3-phosphate
M. gilvum PYR-GCKMflv_3989-7e-6964.50% (200) CDP-diacylglycerol--glycerol-3-phosphate
M. tuberculosis H37RvRv2746cpgsA33e-8880.61% (196) CDP-diacylglycerol--glycerol-3-phosphate
M. leprae Br4923MLBr_00979-1e-7476.37% (182) CDP-diacylglycerol--glycerol-3-phosphate
M. abscessus ATCC 19977MAB_3071c-7e-6057.53% (186) PGP synthase PgsA3 (phosphatidylglycerophosphate synthase)
M. marinum MMMAR_1969pgsA31e-10299.47% (189) PGP synthase PgsA3
M. avium 104MAV_3637pgsA4e-7375.00% (184) CDP-diacylglycerol--glycerol-3-phosphate
M. smegmatis MC2 155MSMEG_2692pgsA7e-6866.67% (195) CDP-diacylglycerol--glycerol-3-phosphate
M. thermoresistible (build 8)TH_0577pgsA31e-6468.33% (180) PROBABLE PGP SYNTHASE PGSA3
M. vanbaalenii PYR-1Mvan_2395-8e-6967.53% (194) CDP-diacylglycerol--glycerol-3-phosphate

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3989|M.gilvum_PYR-GCK          ----------------MCNQYSVAVPGQPHTDPVVPRARVANIANVLTGI
Mvan_2395|M.vanbaalenii_PYR-1       ----------------------MAVPGQPHTDPVVPRARVANLANLLTGI
MSMEG_2692|M.smegmatis_MC2_155      ------------------------MPGQPSTDPVVPRARVANLANVLTGI
TH_0577|M.thermoresistible__bu      ---------------------------------------VANLANALTGV
MUL_3388|M.ulcerans_Agy99           MTFGHEKTVSTSAAGRLVNRYSVAVSGQPQTGQVPGTVGIANLANVLTGL
MMAR_1969|M.marinum_M               ---------------------------------MPGTAGIANLANVLTGL
Mb2767c|M.bovis_AF2122/97           --------MSRS------TRYSVAVSAQPETGQIAGRARIANLANILTLL
Rv2746c|M.tuberculosis_H37Rv        --------MSRS------TRYSVAVSAQPETGQIAGRARIANLANILTLL
MLBr_00979|M.leprae_Br4923          ---------------------------------MVDCVRIANLANILTGL
MAV_3637|M.avium_104                ---------------------------------MVGRANIANLANTLTLL
MAB_3071c|M.abscessus_ATCC_199      --------------------MPMPPETQPDSAASAAPVPVLNIANILTVL
                                                                           : *:** ** :

Mflv_3989|M.gilvum_PYR-GCK          RMALVPVFLVALFVGDGHETFWRLTAFTIFLVAVITDRLDGALARSYGMV
Mvan_2395|M.vanbaalenii_PYR-1       RMALVPVFLFALFAGDGQETSWRITAFVVFAVAVITDRFDGALARSYGMV
MSMEG_2692|M.smegmatis_MC2_155      RMALVPVFLVFLFTDGGHEFFWRMAAFTVFAVAVITDRFDGALARSYGMV
TH_0577|M.thermoresistible__bu      RLLLVPVFLILLFVGDGHETSWRIGAFAVFAVAVITDRFDGALARSYGMV
MUL_3388|M.ulcerans_Agy99           RFVLVPIFLYLLFYDGGHQTTFRIAAWAVFAVASITDRFDGLLARNYGMA
MMAR_1969|M.marinum_M               RFVLVPIFLYLLFYDGGHQTTFRIAAWAVFAVASITDRFDGLLARNYGMA
Mb2767c|M.bovis_AF2122/97           RLVMVPVFLLALFYGGGHHSAARVVAWAIFATACITDRFDGLLARNYGMA
Rv2746c|M.tuberculosis_H37Rv        RLVMVPVFLLALFYGGGHHSAARVVAWAIFATACITDRFDGLLARNYGMA
MLBr_00979|M.leprae_Br4923          RLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLLARRYGMA
MAV_3637|M.avium_104                RLVLVPVFLLALFAGDGHETGFRILAFLIFAFACITDRLDGLLARNYGMA
MAB_3071c|M.abscessus_ATCC_199      RIVLVPVFVVVLFTEGGHQSSWRIAAFGVFALAIATDRYDGILARRYGLI
                                    *: :**:*:  **  .*:.   *: *: :*  *  *** ** *** **: 

Mflv_3989|M.gilvum_PYR-GCK          TEFGTLADPIADKMLIGSALVGLSILGDLPWWVTVVILVREVAVTVLRLV
Mvan_2395|M.vanbaalenii_PYR-1       TEFGTLADPIADKALIGSALVGLSVLGDLPWWVTVVILVRELGVTLLRLV
MSMEG_2692|M.smegmatis_MC2_155      TEFGALADPIADKALIGAALIGLSMLGDLPWWVTAVVLAREIGITLMRLA
TH_0577|M.thermoresistible__bu      TEFGTLADPIADKALIGAALIGLSLLGDLPWWVTAVILVREIGITALRFA
MUL_3388|M.ulcerans_Agy99           TEFGAFVDPIADKALIGAALIGLSMLNDLPWWVTVLILSRELGVTMLRLA
MMAR_1969|M.marinum_M               TEFGAFVDPIADKALIGAALIGLSMLNDLPWWVTVLILSRELGVTMLRLA
Mb2767c|M.bovis_AF2122/97           TEFGAFVDPIADKTLIGSALIGLSMLGDLPWWVTVLILTRELGVTVLRLA
Rv2746c|M.tuberculosis_H37Rv        TEFGAFVDPIADKTLIGSALIGLSMLGDLPWWVTVLILTRELGVTVLRLA
MLBr_00979|M.leprae_Br4923          TEFGAFVDPIADKTLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLA
MAV_3637|M.avium_104                TEFGAFVDPIADKTLVGSALIGLSMLGELPWWITVLILAREFGVTVLRLA
MAB_3071c|M.abscessus_ATCC_199      TPFGQLADPIADKALICAALVGLSLLGDLSWWVTAVILVREIGITVLRFS
                                    * ** :.****** *: :**:***:*.:*.**:*.::: **..:* :*: 

Mflv_3989|M.gilvum_PYR-GCK          VLRRGVIPASRGGKIKTLVQAVAIGLFVMPLS---GAWLTGAWVIMAAAG
Mvan_2395|M.vanbaalenii_PYR-1       VLRRGVIPASRGGKLKTLVQAVAIGLFVLPLS---DGWLTGAWVIMLAAV
MSMEG_2692|M.smegmatis_MC2_155      VLRHGVIPASRGGKLKTTVQAVAIGLFVMPLYAWSPVWTTVAWAIMWAAV
TH_0577|M.thermoresistible__bu      VLRHGVIPASRGGKLKTLAQAVAIGLFVLPLANWAPVWSTVAWGIMAVAV
MUL_3388|M.ulcerans_Agy99           VIRRGVIPASWGGKLKTVVQAVAIGLFVLPLSG---PLHMAAVVVMAAAI
MMAR_1969|M.marinum_M               VIRRGVIPASWGGKLKTVVQAVAIGLFVLPLSG---PLHMAAVVVMAAAI
Mb2767c|M.bovis_AF2122/97           VIRRGVIPASWGGKLKTFVQAVAIGLFVLPLSG---PLHVAAVVVMAAAI
Rv2746c|M.tuberculosis_H37Rv        VIRRGVIPASWGGKLKTFVQAVAIGLFVLPLSG---PLHVAAVVVMAAAI
MLBr_00979|M.leprae_Br4923          VIHRGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAAVVMAVAV
MAV_3637|M.avium_104                VIRRGVIPASWGGKLKTVVQVFAIGLFVLPWAGTPGPFRVGAAVVMGAAI
MAB_3071c|M.abscessus_ATCC_199      VLRHGVIPANRGGKLKTLVQSLAIAGYLLPLTG---HWHTAALILMGLAV
                                    *:::*****. ***:** .* .**. :::*           *  :*  * 

Mflv_3989|M.gilvum_PYR-GCK          VLTVLTGVDYFVSAVRDWRRQSPGR-
Mvan_2395|M.vanbaalenii_PYR-1       ALTVTTGVDYFVSAVRDWRGRSAGQ-
MSMEG_2692|M.smegmatis_MC2_155      VLTVLTGADYVVSAIRDSRGRPADN-
TH_0577|M.thermoresistible__bu      VLTVFTGVDYVVSAVRDSRGRSAGH-
MUL_3388|M.ulcerans_Agy99           VLTVVTGIDYVASTVREIRAGKRAS-
MMAR_1969|M.marinum_M               VLTVVTGIDYVASTVREIRAGKRAS-
Mb2767c|M.bovis_AF2122/97           LLTVITGVDYVARALRDIGGIRQTAS
Rv2746c|M.tuberculosis_H37Rv        LLTVITGVDYVARALRDIGGIRQTAS
MLBr_00979|M.leprae_Br4923          VLTVVTGVDYVAGTIRAVRGVHQTAS
MAV_3637|M.avium_104                VLTVITGIDYVVSTVREVR---RTAA
MAB_3071c|M.abscessus_ATCC_199      ALTVITGIDYLVQALRPRPKTP----
                                     *** ** **.. ::*