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MKPVLAQNRVLTVPNLLSAIRLALIPVFVYVMLIAPAHGWAVAILMFSGASDWADGKIARLLNQSSRLGV LLDPAVDRLYMITVPIVLGLSGIVPWWFIAALLARDAALALTLPALWGRGVSALPVTYVGKAATFALMAG FPALLLGQWDALWSRALKACGWAFLIWGLYAYLWAFVLYIVQMTMVVRRIPKIKHRTFQPVGRNAGGDG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3041 | pgsA2 | - | 100% (209) | CDP-diacylglycerol--glycerol-3-phosphate 3- phosphatidyltransferase PgsA2 |
| M. ulcerans Agy99 | MUL_3388 | pgsA3 | 4e-11 | 26.15% (130) | PGP synthase PgsA3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1853 | pgsA2 | 8e-93 | 77.03% (209) | CDP-diacylglycerol--glycerol-3-phosphate |
| M. gilvum PYR-GCK | Mflv_3407 | - | 2e-71 | 63.49% (189) | CDP-alcohol phosphatidyltransferase |
| M. tuberculosis H37Rv | Rv1822 | pgsA2 | 9e-93 | 77.03% (209) | CDP-diacylglycerol--glycerol-3-phosphate |
| M. leprae Br4923 | MLBr_02081 | pgsA2 | 1e-88 | 76.53% (196) | CDP-diacylglycerol-glycerol-3-phosphate |
| M. abscessus ATCC 19977 | MAB_2398 | - | 2e-73 | 63.02% (192) | putative phosphatidylglycerophosphate synthase PgsA2 |
| M. marinum M | MMAR_2699 | pgsA2 | 1e-118 | 99.04% (209) | CDP-diacylglycerol--glycerol-3-phosphate 3- |
| M. avium 104 | MAV_2893 | - | 9e-92 | 78.50% (200) | CDP-alcohol phosphatidyltransferase |
| M. smegmatis MC2 155 | MSMEG_3652 | - | 3e-76 | 68.78% (189) | CDP-diacylglycerol-glycerol-3-phosphate |
| M. thermoresistible (build 8) | TH_0577 | pgsA3 | 7e-15 | 28.49% (179) | PROBABLE PGP SYNTHASE PGSA3 |
| M. vanbaalenii PYR-1 | Mvan_3140 | - | 6e-68 | 66.67% (186) | CDP-alcohol phosphatidyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3407|M.gilvum_PYR-GCK MDHAP---VRDRVMTVPNALSVIRLVLVPVFLYLLLV--ADLTGWAV---
Mvan_3140|M.vanbaalenii_PYR-1 MDHAP---VRDRVLTVPNALSVIRLVLVPVFLYLLLA--AGATGWAV---
MSMEG_3652|M.smegmatis_MC2_155 MPAADE--GRDRVLTVPNVLSFVRLLLVPVFLYLLLV--AHAQGWAV---
MUL_3041|M.ulcerans_Agy99 MKPVL---AQNRVLTVPNLLSAIRLALIPVFVYVMLI--APAHGWAV---
MMAR_2699|M.marinum_M MKPVL---AQNRVLTVPNLLSAIRLALIPVFVYVMLI--APAHGWAV---
Mb1853|M.bovis_AF2122/97 MEPVL---TQNRVLTVPNMLSVIRLALIPAFVYVVLS--AHANGWGV---
Rv1822|M.tuberculosis_H37Rv MEPVL---TQNRVLTVPNMLSVIRLALIPAFVYVVLS--AHANGWGV---
MLBr_02081|M.leprae_Br4923 MESVC---PPNRVLTVPNLLSAVRLALIPAFVYVLLV--MHADGWAV---
MAV_2893|M.avium_104 MEPVL---PPNRVLTVPNALSAVRLALVPVFVYALLV--AHANGWAV---
MAB_2398|M.abscessus_ATCC_1997 MGTAEPSTGDDRIVTVPNLLSVIRLAFIPLFLYLLLV--RHADGWAV---
TH_0577|M.thermoresistible__bu ------------VANLANALTGVRLLLVPVFLILLFVGDGHETSWRIGAF
: .:.* *: :** ::* *: :: .* :
Mflv_3407|M.gilvum_PYR-GCK AVLMFSGASDWADGKIARLCANQSSRLGELLDPAVDRIYMITVPVSMAVA
Mvan_3140|M.vanbaalenii_PYR-1 AILMFSGASDWADGKIARLFDGQSSRLGELLDPLVDRIYMVVVPISMAAV
MSMEG_3652|M.smegmatis_MC2_155 AVLMFSGFSDWADGKIARLVANQSSRLGELLDPLVDRIYMVTVPVALALY
MUL_3041|M.ulcerans_Agy99 AILMFSGASDWADGKIARLLN-QSSRLGVLLDPAVDRLYMITVPIVLGLS
MMAR_2699|M.marinum_M AILMFSGASDWADGKIARLLN-QSSRLGVLLDPAVDRLYMITVPIVLGLS
Mb1853|M.bovis_AF2122/97 AILVFSGVSDWADGKIARLLN-QSSRLGALLDPAVDRLYMVTVPIVFGLS
Rv1822|M.tuberculosis_H37Rv AILVFSGVSDWADGKIARLLN-QSSRLGALLDPAVDRLYMVTVPIVFGLS
MLBr_02081|M.leprae_Br4923 VILVFSGVSDWADGKIARLLD-QYSRLGVLLDPAVDRLYMVTIPVVLALS
MAV_2893|M.avium_104 AILMFSGASDWADGKIARLLN-QSSRLGVLLDPAVDRLYMVVVPVVLALS
MAB_2398|M.abscessus_ATCC_1997 AILMLSGFTDWADGKIARLMN-QSSHLGTLLDPAADRLYMVTTPIAFAIR
TH_0577|M.thermoresistible__bu AVFAVAVITDRFDGALARSYG-MVTEFGTLADPIADKALIGAALIGLSLL
.:: .: :* ** :** :.:* * ** .*: : . : :.
Mflv_3407|M.gilvum_PYR-GCK GVIPWWVVGLLLGRDAVLAATLPLLRGRGLTALPVTYIGKAATFALMSGL
Mvan_3140|M.vanbaalenii_PYR-1 GFVPWWVVALLLGRDLVLAGTLPLLRRRGLTALPVTYIGKAATFALMSGL
MSMEG_3652|M.smegmatis_MC2_155 GAVPWWLVLTLLGRDAVLAATLPVLRSRGLAALPVTYIGKAATFALMSGF
MUL_3041|M.ulcerans_Agy99 GIVPWWFIAALLARDAALALTLPALWGRGVSALPVTYVGKAATFALMAGF
MMAR_2699|M.marinum_M GIVPWWFIAALLARDAALALTLPALWSRGVSALPVTYVGKAATFALMAGF
Mb1853|M.bovis_AF2122/97 GIVPWWFVLTLLTRDALLAGTLPLLWSRGLSALPVTYVGKAATFGFMVGF
Rv1822|M.tuberculosis_H37Rv GIVPWWFVLTLLTRDALLAGTLPLLWSRGLSALPVTYVGKAATFGFMVGF
MLBr_02081|M.leprae_Br4923 GIVPWWFVVALLARDVLLTATLPLLWSRGLLSLPVTYIGKAATFSLMVGF
MAV_2893|M.avium_104 GIVPWWFVVVLLVRDGLLAATLPLLWSRGLSALPVTYIGKAATFALMCGF
MAB_2398|M.abscessus_ATCC_1997 DIVPWWIVITLLARDLILTLGLPVVRRRGIEALPVIYIGKAATFALMSAF
TH_0577|M.thermoresistible__bu GDLPWWVTAVILVREIGITALRFAVLRHG--VIPASRGGKLKTLAQAVAI
. :***. :* *: :: : :* :*. ** *:. .:
Mflv_3407|M.gilvum_PYR-GCK PLVLLGQLDGQWSRVVLAIGWGFLVWGMAMYVWSGILYLLQVGMVMRTMP
Mvan_3140|M.vanbaalenii_PYR-1 PLVLLGQVDAQWARVVLALGWGFLIWGLAMYLWSGALYLVQVGMVMRTLP
MSMEG_3652|M.smegmatis_MC2_155 PLVLLGQWDALWSRVVLACGWAFLIWGLLLYLWSAVLYLMQVVLVVRRMD
MUL_3041|M.ulcerans_Agy99 PALLLGQWDALWSRALKACGWAFLIWGLYAYLWAFVLYIVQMTMVVRRIP
MMAR_2699|M.marinum_M PVLLLGQWDALWSRALKACGWAFLIWGLYAYLWAFVLYIVQMTMVVRRIP
Mb1853|M.bovis_AF2122/97 PTILLGQCDPLWSHVLLACGWAFLIWGMYAYLWAFVLYAVQMTMVVRQMP
Rv1822|M.tuberculosis_H37Rv PTILLGQCDPLWSHVLLACGWAFLIWGMYAYLWAFVLYAVQMTMVVRQMP
MLBr_02081|M.leprae_Br4923 PFVLLGTWDTLWSRVLGACGWAFLIWGTYAYLWAFVLYVVQMTMVVRWMP
MAV_2893|M.avium_104 PLVLLGTWDALWSRVVGACGWAFLIWGLYAYLWAFAQYAVQMTLVVRRMP
MAB_2398|M.abscessus_ATCC_1997 PLILIGEWDSLWGRVIGPCGWAFLIWGLGMYLWTFVLYVAQIVMIVRRLP
TH_0577|M.thermoresistible__bu GLFVLPLAN--WAPVWSTVAWGIMAVAVVLTVFTGVDYVVSAVRDSRGRS
.:: : *. . . .*.:: . ::: * . *
Mflv_3407|M.gilvum_PYR-GCK RVRR--------------
Mvan_3140|M.vanbaalenii_PYR-1 PS----------------
MSMEG_3652|M.smegmatis_MC2_155 PVR---------------
MUL_3041|M.ulcerans_Agy99 KIKHRTFQPVGRNAGGDG
MMAR_2699|M.marinum_M KIKHRTFQPVGRNAGGDG
Mb1853|M.bovis_AF2122/97 KLKGRAHRPAAQNAGERG
Rv1822|M.tuberculosis_H37Rv KLKGRAHRPAAQNAGERG
MLBr_02081|M.leprae_Br4923 KIKHQAHRQFAGKAR---
MAV_2893|M.avium_104 KVHRASRPSTMAKVVDHG
MAB_2398|M.abscessus_ATCC_1997 KVDT--------------
TH_0577|M.thermoresistible__bu AGH---------------